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🍽️ bufexamac,(prescription)

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  1. Dermatological Conditions: Bufexamac is commonly used to treat various dermatological conditions, including:

    • Eczema: It helps reduce inflammation, itching, and redness associated with eczematous skin conditions.
    • Contact Dermatitis: Bufexamac can alleviate symptoms of contact dermatitis, such as itching, burning, and swelling, caused by contact with irritants or allergens.
    • Allergic Skin Reactions: It may be used to relieve symptoms of allergic skin reactions, including hives (urticaria) and allergic dermatitis.

  2. Anti-inflammatory Action: Bufexamac exerts its therapeutic effects by inhibiting the synthesis of inflammatory mediators, such as prostaglandins and leukotrienes. By reducing inflammation in the skin, it helps alleviate symptoms of various dermatological conditions.

  3. Analgesic Effect: In addition to its anti-inflammatory properties, bufexamac has mild analgesic (pain-relieving) effects. It can help alleviate pain and discomfort associated with inflammatory skin conditions, providing symptomatic relief to patients.

  4. Topical Formulation: Bufexamac is typically available in topical formulations, such as creams, ointments, or gels, for external application to the affected skin area. Topical application allows for localized treatment of skin inflammation and reduces systemic exposure to the medication.

  5. Mild Side Effects: Common side effects associated with bufexamac use may include skin irritation, burning, stinging, or itching at the site of application. These side effects are usually mild and transient, and they often resolve with continued use or upon discontinuation of the medication.

  6. Allergic Reactions: Although rare, some individuals may experience allergic reactions to bufexamac, including severe skin irritation, rash, or swelling. Patients should discontinue use and seek medical attention if they experience signs of an allergic reaction.

  7. Contraindications: Bufexamac should not be used in individuals with known hypersensitivity to the drug or its components. It is contraindicated in patients with open wounds, broken skin, or infected skin lesions, as it may increase the risk of systemic absorption and adverse effects.

  8. Pregnancy and Lactation: The safety of bufexamac use during pregnancy and breastfeeding has not been well established. Pregnant or lactating women should consult with a healthcare professional before using bufexamac to weigh the potential benefits against the risks.

  9. Drug Interactions: Bufexamac is primarily used topically, which minimizes the risk of systemic drug interactions. However, patients should inform their healthcare providers about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of bufexamac,(prescription) On Probiotics

Rank Probiotic Impact
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces

Bacteria Impacted by bufexamac,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?

📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Escherichia genus Decreases
0 1 Roseburia genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bilophila genus Decreases
0 1 Coprococcus genus Decreases
0 1 Eggerthella genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Lachnospira genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Streptococcus genus Decreases
0 1 Veillonella genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Veillonella parvula species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Escherichia coli species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Coprococcus comes species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Roseburia hominis species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of bufexamac,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.3 0.3
Acne 0.6 0.6
ADHD 1.4 0.6 1.33
Age-Related Macular Degeneration and Glaucoma 0.5 0.5
Allergic Rhinitis (Hay Fever) 1.2 0.7 0.71
Allergies 2.4 0.6 3
Allergy to milk products 1 0.9 0.11
Alzheimer's disease 2.8 2.7 0.04
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.8 1 0.8
Ankylosing spondylitis 2.2 0.9 1.44
Anorexia Nervosa 0.3 1.4 -3.67
Antiphospholipid syndrome (APS) 0.7 0.3 1.33
Asthma 3.3 1.4 1.36
Atherosclerosis 1 0.8 0.25
Atrial fibrillation 1.5 1.2 0.25
Autism 3.5 3.8 -0.09
Autoimmune Disease 0.9 0.5 0.8
Barrett esophagus cancer 0.6 0.3 1
benign prostatic hyperplasia 0.6 0.3 1
Biofilm 1.5 1.5
Bipolar Disorder 1.5 1.4 0.07
Brain Trauma 0.3 0.8 -1.67
Breast Cancer 1.2 1.2
Cancer (General) 0.6 0.7 -0.17
Carcinoma 2.8 0.3 8.33
Celiac Disease 1.3 1.2 0.08
Cerebral Palsy 0.9 0.8 0.13
Chronic Fatigue Syndrome 2.5 1.4 0.79
Chronic Kidney Disease 1.5 1.4 0.07
Chronic Lyme 0.8 -0.8
Chronic Obstructive Pulmonary Disease (COPD) 1.9 2 -0.05
Chronic Urticaria (Hives) 1.6 0 0
Coagulation / Micro clot triggering bacteria 1.3 0.8 0.63
Cognitive Function 1.1 0.8 0.38
Colorectal Cancer 3.8 1.3 1.92
Constipation 1.6 0.5 2.2
Coronary artery disease 1.3 1.4 -0.08
COVID-19 3.1 2.2 0.41
Crohn's Disease 4.1 1.9 1.16
Cushing's Syndrome (hypercortisolism) 0.3 -0.3
cystic fibrosis 1 0.8 0.25
d-lactic acidosis (one form of brain fog) 0.4 0.4
deep vein thrombosis 2.4 1.1 1.18
Denture Wearers Oral Shifts 1.6 1.6
Depression 4.9 3.5 0.4
Dermatomyositis 0.3 0.3
Eczema 1.5 0.6 1.5
Endometriosis 1.9 1.8 0.06
Eosinophilic Esophagitis 0.3 0.6 -1
Epilepsy 1.9 0.3 5.33
erectile dysfunction 1.2 1.2
Fibromyalgia 0.8 1 -0.25
Functional constipation / chronic idiopathic constipation 2.2 1.2 0.83
gallstone disease (gsd) 1.4 0.8 0.75
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.1 0.6 0.83
Generalized anxiety disorder 2.5 1.4 0.79
Glioblastoma 0.3 -0.3
Gout 1.2 0.3 3
Graves' disease 0.6 1.7 -1.83
Gulf War Syndrome 0.6 0 0
Halitosis 1.6 0.3 4.33
Hashimoto's thyroiditis 1.4 0.9 0.56
Heart Failure 2.5 0.5 4
hemorrhagic stroke 0.3 0.3
Hidradenitis Suppurativa 1.4 0.3 3.67
High Histamine/low DAO 1 1
hypercholesterolemia (High Cholesterol) 0.4 0.4
hyperglycemia 1.9 0.3 5.33
Hyperlipidemia (High Blood Fats) 0.3 0.3
hypersomnia 0.3 -0.3
hypertension (High Blood Pressure 1.5 2 -0.33
Hypothyroidism 0.6 -0.6
Hypoxia 1.3 1.3
IgA nephropathy (IgAN) 1.2 1.6 -0.33
Inflammatory Bowel Disease 3.9 2.8 0.39
Insomnia 1.4 1.7 -0.21
Intelligence 1 1
Intracranial aneurysms 0.6 0.3 1
Irritable Bowel Syndrome 3.6 2 0.8
ischemic stroke 1.3 1.4 -0.08
Liver Cirrhosis 4.6 2.7 0.7
Long COVID 2.6 2.2 0.18
Low bone mineral density 1.1 -1.1
Lung Cancer 0.9 0.9
Lymphoma 0.9 0.9
Mast Cell Issues / mastitis 1.3 0.3 3.33
ME/CFS with IBS 0.3 0.5 -0.67
ME/CFS without IBS 1.2 0.3 3
membranous nephropathy 0.3 0.3
Menopause 0.3 0.5 -0.67
Metabolic Syndrome 3.4 2.4 0.42
Mood Disorders 5.1 3.7 0.38
multiple chemical sensitivity [MCS] 0.9 0.9
Multiple Sclerosis 3.1 1.6 0.94
Multiple system atrophy (MSA) 0.1 0.1
myasthenia gravis 0.9 0.5 0.8
neuropathic pain 0.3 1.2 -3
Neuropathy (all types) 0.6 1.1 -0.83
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.7 1.4 0.93
NonCeliac Gluten Sensitivity 0.6 0.3 1
Obesity 3.4 3.7 -0.09
obsessive-compulsive disorder 2.2 0.9 1.44
Osteoarthritis 1.2 0.6 1
Osteoporosis 2.2 0.6 2.67
pancreatic cancer 1.9 0.6 2.17
Parkinson's Disease 3.3 2.9 0.14
Polycystic ovary syndrome 2.3 1.4 0.64
Postural orthostatic tachycardia syndrome 0.3 -0.3
primary biliary cholangitis 0.6 0.6 0
Primary sclerosing cholangitis 1.8 0.3 5
Psoriasis 1 1.1 -0.1
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.3 1.7 0.94
Rosacea 0.5 -0.5
Schizophrenia 3.5 1.7 1.06
scoliosis 0.7 0.5 0.4
Sjögren syndrome 1.8 0.3 5
Sleep Apnea 0.9 1.4 -0.56
Slow gastric motility / Gastroparesis 1 1
Small Intestinal Bacterial Overgrowth (SIBO) 1.9 1.9
Stress / posttraumatic stress disorder 1.6 1.7 -0.06
Systemic Lupus Erythematosus 2.6 0.9 1.89
Tic Disorder 0.3 0.3
Tourette syndrome 0.3 0.3 0
Type 1 Diabetes 2.1 1.4 0.5
Type 2 Diabetes 3.4 2.5 0.36
Ulcerative colitis 3.3 1.5 1.2
Unhealthy Ageing 2.5 0.8 2.13
Vitiligo 0.9 0.2 3.5

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