Collinsella: NCBI 102106, [genus]

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| Collinsella| Collinsella Kageyama et al. 1999 emend. Kageyama and Benno 2000

1. Abundance in the Gut Microbiota:

   • Collinsella is a member of the normal human gut microbiota, and its abundance can vary among individuals. The gut microbiota plays a crucial role in digestion, metabolism, and the modulation of the immune system.

2. Fermentation and Short-Chain Fatty Acid Production:

   • Like many other bacteria in the gut, Collinsella is involved in the fermentation of dietary fibers. This process produces short-chain fatty acids (SCFAs), including butyrate, acetate, and propionate. SCFAs are known for their potential benefits to gut health and overall well-being.

3. Butyrate Production:

   • Butyrate, in particular, is of interest due to its anti-inflammatory properties and its role in supporting the health of the colonic epithelium. Butyrate is an important energy source for the cells lining the colon.

4. Links to Diet:

   • The abundance and activity of Collinsella and other gut bacteria can be influenced by dietary factors. Diets rich in fiber provide substrates for the fermentation process carried out by these bacteria.

5. Associations with Health Conditions:

   • Changes in the abundance of Collinsella have been reported in studies of the gut microbiota in various health conditions. The specific associations can be both increases or decreases, and the significance of these changes in the context of health and disease is an area of ongoing research.

6. Inflammatory Bowel Disease (IBD) and Other Conditions:

   • Some studies have reported associations between the abundance of Collinsella and conditions such as inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. However, the nature of these associations and whether they are causative or consequential are still being investigated.

7. Immunomodulation:

   • The gut microbiota, including Collinsella, can influence the host's immune system. The interactions between gut bacteria and the immune system are complex and involve the regulation of immune responses in the gut.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Collinsella impacts on other bacteria of the same rank

Other bacteria of the same rank impacting Collinsella

R2	Slope	Tax Name	Parent Chart
0.6103550791740417	0.8992753624916077	Parolsenella	Parent Taxa
0.3339836597442627	0.5853127837181091	Parafannyhessea	Parent Taxa