Klebsiella pneumoniae subsp. rhinoscleromatis: NCBI 39831, [subspecies]

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1. Rhinoscleroma: The primary health impact of Klebsiella pneumoniae subsp. rhinoscleromatis is the development of rhinoscleroma. This condition typically manifests as nasal obstruction, nasal discharge, epistaxis (nosebleeds), and the formation of nodules or granulomatous lesions in the nasal passages. As the disease progresses, it can lead to deformities of the nasal structures and potentially affect nearby tissues and organs.

2. Chronic Infection: Rhinoscleroma is characterized by its chronic nature, with the lesions slowly progressing over time if left untreated. The chronic inflammation and tissue damage associated with rhinoscleroma can lead to significant morbidity and functional impairment, particularly in advanced cases.

3. Complications: In severe cases or when left untreated, rhinoscleroma can lead to complications such as secondary infections, septal perforation, destruction of nasal cartilage and bone, and even involvement of adjacent structures such as the larynx, trachea, and lungs. These complications can exacerbate the severity of symptoms and pose challenges for treatment.

4. Rare Occurrence: Rhinoscleroma is considered a rare disease, and cases are primarily reported in regions where the condition is endemic, such as certain parts of Africa, Asia, and Central and South America. However, with increased global travel and migration, cases may also occur in non-endemic regions.

5. Diagnostic Challenges: Diagnosing rhinoscleroma can be challenging, particularly in regions where the disease is not commonly encountered. It often requires a combination of clinical evaluation, imaging studies (such as computed tomography), and microbiological tests (such as culture and identification of Klebsiella pneumoniae subsp. rhinoscleromatis from nasal swabs or biopsy specimens).

6. Treatment: Treatment of rhinoscleroma typically involves prolonged antibiotic therapy, often with multiple antibiotics in combination to target the bacteria effectively. In some cases, surgical intervention may be necessary to remove obstructive lesions or correct structural deformities caused by the disease.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Klebsiella pneumoniae subsp. rhinoscleromatis impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart

Other bacteria of the same rank impacting Klebsiella pneumoniae subsp. rhinoscleromatis

R2	Slope	Tax Name	Parent Chart
0.26350417733192444	0.6011069416999817	Klebsiella variicola subsp. tropica	Parent Taxa
0.250457763671875	0.6201963424682617	Klebsiella pneumoniae subsp. pneumoniae	Parent Taxa