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Partial list of Citations used for Recommendations or Conditions

Recent additions may not be included but will usually appear in 24 hrs or less.

Rational Source
Oral supplementation of healthy adults with 2`-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota. ✅
The British journal of nutrition (Br J Nutr ) Vol: 116 Issue 8 Pages: 1356-1368
Pub: 2016 Oct Epub: 2016 Oct 10 Authors Elison E , Vigsnaes LK , Rindom Krogsgaard L , Rasmussen J , Sørensen N , McConnell B , Hennet T , Sommer MO , Bytzer P ,
Oral supplementation of healthy adults with 2`-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota. ✅
The British journal of nutrition (Br J Nutr ) Vol: 116 Issue 8 Pages: 1356-1368
Pub: 2016 Oct Epub: 2016 Oct 10 Authors Elison E , Vigsnaes LK , Rindom Krogsgaard L , Rasmussen J , Sørensen N , McConnell B , Hennet T , Sommer MO , Bytzer P ,
Oral supplementation of healthy adults with 2`-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota. ✅
The British journal of nutrition (Br J Nutr ) Vol: 116 Issue 8 Pages: 1356-1368
Pub: 2016 Oct Epub: 2016 Oct 10 Authors Elison E , Vigsnaes LK , Rindom Krogsgaard L , Rasmussen J , Sørensen N , McConnell B , Hennet T , Sommer MO , Bytzer P ,
Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed. ✅ Go to Publication ✅
Journal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr ) Vol: 60 Issue 6 Pages: 825-33
Pub: 2015 Jun Epub: Authors Wang M , Li M , Wu S , Lebrilla CB , Chapkin RS , Ivanov I , Donovan SM ,
Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed. ✅ Go to Publication ✅
Journal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr ) Vol: 60 Issue 6 Pages: 825-33
Pub: 2015 Jun Epub: Authors Wang M , Li M , Wu S , Lebrilla CB , Chapkin RS , Ivanov I , Donovan SM ,
Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed. ✅ Go to Publication ✅
Journal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr ) Vol: 60 Issue 6 Pages: 825-33
Pub: 2015 Jun Epub: Authors Wang M , Li M , Wu S , Lebrilla CB , Chapkin RS , Ivanov I , Donovan SM ,
Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed. ✅ Go to Publication ✅
Journal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr ) Vol: 60 Issue 6 Pages: 825-33
Pub: 2015 Jun Epub: Authors Wang M , Li M , Wu S , Lebrilla CB , Chapkin RS , Ivanov I , Donovan SM ,
Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice. ✅ Go to Publication ✅
PloS one (PLoS One ) Vol: 14 Issue 7 Pages: e0219366
Pub: 2019 Epub: 2019 Jul 8 Authors Rogier R , Ederveen THA , Wopereis H , Hartog A , Boekhorst J , van Hijum SAFT , Knol J , Garssen J , Walgreen B , Helsen MM , van der Kraan PM , van Lent PLEM , van de Loo FAJ , Abdollahi-Roodsaz S , Koenders MI ,
Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice. ✅ Go to Publication ✅
PloS one (PLoS One ) Vol: 14 Issue 7 Pages: e0219366
Pub: 2019 Epub: 2019 Jul 8 Authors Rogier R , Ederveen THA , Wopereis H , Hartog A , Boekhorst J , van Hijum SAFT , Knol J , Garssen J , Walgreen B , Helsen MM , van der Kraan PM , van Lent PLEM , van de Loo FAJ , Abdollahi-Roodsaz S , Koenders MI ,
Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus. ✅ Go to Publication ✅
ACS infectious diseases (ACS Infect Dis ) Vol: 3 Issue 8 Pages: 595-605
Pub: 2017 Aug 11 Epub: 2017 Jun 13 Authors Ackerman DL , Doster RS , Weitkamp JH , Aronoff DM , Gaddy JA , Townsend SD ,
2`-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. ✅
Nutrients (Nutrients ) Vol: 12 Issue 4 Pages:
Pub: 2020 Apr 5 Epub: 2020 Apr 5 Authors Lee S , Goodson M , Vang W , Kalanetra K , Barile D , Raybould H ,
2`-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. ✅
Nutrients (Nutrients ) Vol: 12 Issue 4 Pages:
Pub: 2020 Apr 5 Epub: 2020 Apr 5 Authors Lee S , Goodson M , Vang W , Kalanetra K , Barile D , Raybould H ,
2`-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. ✅
Nutrients (Nutrients ) Vol: 12 Issue 4 Pages:
Pub: 2020 Apr 5 Epub: 2020 Apr 5 Authors Lee S , Goodson M , Vang W , Kalanetra K , Barile D , Raybould H ,
2`-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. ✅
Nutrients (Nutrients ) Vol: 12 Issue 4 Pages:
Pub: 2020 Apr 5 Epub: 2020 Apr 5 Authors Lee S , Goodson M , Vang W , Kalanetra K , Barile D , Raybould H ,
2`-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. ✅
Nutrients (Nutrients ) Vol: 12 Issue 4 Pages:
Pub: 2020 Apr 5 Epub: 2020 Apr 5 Authors Lee S , Goodson M , Vang W , Kalanetra K , Barile D , Raybould H ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
Immunomodulatory and Prebiotic Effects of 2`-Fucosyllactose in Suckling Rats. ✅ Go to Publication ✅
Frontiers in immunology (Front Immunol ) Vol: 10 Issue Pages: 1773
Pub: 2019 Epub: 2019 Jul 31 Authors Azagra-Boronat I , Massot-Cladera M , Mayneris-Perxachs J , Knipping K , Van`t Land B , Tims S , Stahl B , Garssen J , Franch À , Castell M , Rodríguez-Lagunas MJ , Pérez-Cano FJ ,
The Protective Effects of 2`-Fucosyllactose against E. Coli O157 Infection Are Mediated by the Regulation of Gut Microbiota and the Inhibition of Pathogen Adhesion. ✅
Nutrients (Nutrients ) Vol: 12 Issue 5 Pages:
Pub: 2020 May 1 Epub: 2020 May 1 Authors Wang Y , Zou Y , Wang J , Ma H , Zhang B , Wang S ,
The Protective Effects of 2`-Fucosyllactose against E. Coli O157 Infection Are Mediated by the Regulation of Gut Microbiota and the Inhibition of Pathogen Adhesion. ✅
Nutrients (Nutrients ) Vol: 12 Issue 5 Pages:
Pub: 2020 May 1 Epub: 2020 May 1 Authors Wang Y , Zou Y , Wang J , Ma H , Zhang B , Wang S ,
The Protective Effects of 2`-Fucosyllactose against E. Coli O157 Infection Are Mediated by the Regulation of Gut Microbiota and the Inhibition of Pathogen Adhesion. ✅
Nutrients (Nutrients ) Vol: 12 Issue 5 Pages:
Pub: 2020 May 1 Epub: 2020 May 1 Authors Wang Y , Zou Y , Wang J , Ma H , Zhang B , Wang S ,
The Protective Effects of 2`-Fucosyllactose against E. Coli O157 Infection Are Mediated by the Regulation of Gut Microbiota and the Inhibition of Pathogen Adhesion. ✅
Nutrients (Nutrients ) Vol: 12 Issue 5 Pages:
Pub: 2020 May 1 Epub: 2020 May 1 Authors Wang Y , Zou Y , Wang J , Ma H , Zhang B , Wang S ,
2'-Fucosyllactose alleviates OVA-induced food allergy in mice by ameliorating intestinal microecology and regulating the imbalance of Th2/Th1 proportion. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 14 Issue 24 Pages: 10924-10940
Pub: 2023 Dec 11 Epub: 2023 Dec 11 Authors Kou R , Wang J , Li A , Wang Y , Fan D , Zhang B , Fu W , Liu J , Fu H , Wang S ,
2'-Fucosyllactose alleviates OVA-induced food allergy in mice by ameliorating intestinal microecology and regulating the imbalance of Th2/Th1 proportion. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 14 Issue 24 Pages: 10924-10940
Pub: 2023 Dec 11 Epub: 2023 Dec 11 Authors Kou R , Wang J , Li A , Wang Y , Fan D , Zhang B , Fu W , Liu J , Fu H , Wang S ,
Human milk oligosaccharides and the association with microbiota in colostrum: a pilot study. ✅ Go to Publication ✅
Archives of microbiology (Arch Microbiol ) Vol: 206 Issue 2 Pages: 58
Pub: 2024 Jan 8 Epub: 2024 Jan 8 Authors Sun W , Tao L , Qian C , Xue P , Tong X , Yang L , Lu F , Wan H , Tao Y ,
Human milk oligosaccharides and the association with microbiota in colostrum: a pilot study. ✅ Go to Publication ✅
Archives of microbiology (Arch Microbiol ) Vol: 206 Issue 2 Pages: 58
Pub: 2024 Jan 8 Epub: 2024 Jan 8 Authors Sun W , Tao L , Qian C , Xue P , Tong X , Yang L , Lu F , Wan H , Tao Y ,
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. ✅ Go to Publication ✅
Nature communications (Nat Commun ) Vol: 11 Issue 1 Pages: 3285
Pub: 2020 Jul 3 Epub: 2020 Jul 3 Authors Pichler MJ , Yamada C , Shuoker B , Alvarez-Silva C , Gotoh A , Leth ML , Schoof E , Katoh T , Sakanaka M , Katayama T , Jin C , Karlsson NG , Arumugam M , Fushinobu S , Abou Hachem M ,
Human milk oligosaccharides 2'-fucosyllactose and 3-fucosyllactose attenuate ovalbumin-induced food allergy through immunoregulation and gut microbiota modulation. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 16 Issue 4 Pages: 1267-1283
Pub: 2025 Feb 17 Epub: 2025 Feb 17 Authors Wu S , Chen H , Yu R , Li H , Zhao J , Stanton C , Paul Ross R , Chen W , Yang B ,
High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo. ✅ Go to Publication ✅
European journal of nutrition (Eur J Nutr ) Vol: 64 Issue 5 Pages: 215
Pub: 2025 Jun 9 Epub: 2025 Jun 9 Authors Li X , Li Y , Cheng K , Song T , Wang Y , Zhou H , Xu Y , Chaibou OZ , Wang B , Li H ,
High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo. ✅ Go to Publication ✅
European journal of nutrition (Eur J Nutr ) Vol: 64 Issue 5 Pages: 215
Pub: 2025 Jun 9 Epub: 2025 Jun 9 Authors Li X , Li Y , Cheng K , Song T , Wang Y , Zhou H , Xu Y , Chaibou OZ , Wang B , Li H ,

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