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Symptom Association

The following is based on 3100+ uploaded samples annotated with symptoms and diagnosis. This is not based on bacteria, just symptom self-declarations. All of the raw data is available at Microbiome Prescription Citizen Science Data Share with KEGG: Kyoto Encyclopedia of Genes and Genomes used to estimate Enzymes and Metabolites. This site was originally focused on ME/CFS and then Long COVID, there is some bias towards those conditions.

All items listed are P < 0.005 (or 1 in 200+ chance of happening at random). Using one or more of the following statistical methods:

For background on the need to use multiple processing labs see see The taxonomy nightmare before Christmas….

To see the bacteria shifts for any of these see Bacteria by Symptoms by Lab that are high or low

Picked Symptom


Top results for each lab<
Bottom section shows items reported by all labs with P < <

The bottom section reports on items that all three labs report significant. These items are likely correct for any lab processing. 📹 Video Walkthru   Technical Notes

Bacteria

Probability Lab Bacteria Rank
5.568545140631229E-39 ubiome unclassified Herbaspirillum no rank
8.862630328213883E-18 ubiome unclassified Desulfovibrio no rank
2.468836109638527E-13 ubiome Lactobacillus iners species
8.472507562196085E-08 biomesight Enterococcaceae family
4.360830634681639E-07 ombre Chloroflexia class
4.4436511356950335E-07 biomesight Gardnerella vaginalis species
4.824808771724834E-07 ubiome Parvibacter genus
6.216078946673192E-07 ubiome Fibrobacteria class
6.216078946673192E-07 ubiome Fibrobacterota phylum
6.216078946673192E-07 ubiome Fibrobacterales order
1.945763096337374E-06 ubiome Parvibacter caecicola species
3.0844056230054856E-06 ubiome Fibrobacteraceae family
4.315448787822618E-06 biomesight Haploplasma genus
4.315448787822618E-06 biomesight Haploplasma cavigenitalium species
4.659559356047167E-06 biomesight Chlorobaculum limnaeum species
4.8767825713792455E-06 ombre Desulfonispora genus
4.8767825713792455E-06 ombre Desulfonispora thiosulfatigenes species
5.121746951907156E-06 ombre Thermosediminibacterales order
5.27317764758719E-06 ombre Desulforadius genus
5.411641862617969E-06 biomesight Gardnerella genus
8.435348822606973E-06 ombre Prevotella denticola species
1.1992563991114652E-05 ombre Saccharopolyspora cebuensis species
1.2657742815277183E-05 ombre Saccharopolyspora genus
1.476535604907988E-05 ombre Desulforadius tongensis species
2.110833665924794E-05 biomesight Planococcus genus
2.3473121327550136E-05 ombre Thiocystis violascens species
2.7093436212990645E-05 ubiome Peptoniphilus sp. BV3AC2 species
2.760073968172085E-05 ubiome Puniceicoccales order
2.8459346327780466E-05 biomesight Planococcus columbae species
3.109830771924563E-05 ombre Actinoplanes philippinensis species
3.741732089260874E-05 biomesight Brevibacterium paucivorans species
4.141038418965565E-05 biomesight Coriobacterium genus
4.141038418965565E-05 biomesight Coriobacterium glomerans species
4.199218229886047E-05 ubiome Opitutia class
5.0324826531147094E-05 ubiome Neisseria genus
5.0489477982121626E-05 ombre Thiocystis genus
6.712617665270322E-05 ubiome Negativicoccus genus
7.460316793334467E-05 biomesight Bifidobacterium ruminantium species
7.85741250479769E-05 ombre Dethiosulfovibrio genus
0.00011545227304694026 biomesight Cetobacterium ceti species
0.00012085453760178182 biomesight Roseospira mediosalina species
0.0001293382085381264 ubiome Butyricicoccus pullicaecorum species
0.00013523272333286238 ombre Agromyces genus
0.00013631829428906173 ombre Anaerostipes butyraticus species
0.00014049672065658632 biomesight Vibrio genus
0.00014951267862092435 biomesight Clostridium caliptrosporum species
0.00016236708451911782 biomesight Janthinobacterium genus
0.00017572041889757578 biomesight Nisaea genus
0.00017572041889757578 biomesight Thalassobaculaceae family
0.00017831877752254706 ombre unclassified Actinomycetes no rank
0.00019574730059835607 ubiome Phocaeicola coprocola species
0.00022520529203649852 ubiome Peptoniphilus sp. oral taxon 375 species
0.00023967358727672305 biomesight Dokdonella fugitiva species
0.00024689372212360894 ubiome Gammaproteobacteria class
0.0002584128266059303 ubiome unclassified Prevotella no rank
0.00026316151241947755 biomesight Levilactobacillus genus
0.00027758335776595366 biomesight Dokdonella genus
0.00029249578279618143 ombre Emticicia sediminis species
0.00029425623051414863 ombre Gordoniaceae family
0.00029425623051414863 ombre Gordonia genus
0.00031409239789526033 biomesight Thioalkalivibrio genus
0.0003204412458168715 biomesight Weissella genus
0.0003234118809805876 biomesight Melissococcus genus
0.00032370926514309947 biomesight Winkia neuii species
0.00032370926514309947 biomesight Winkia genus
0.00033001248466044407 ubiome Robinsoniella genus
0.0003360152589992893 biomesight Thioalkalivibrio jannaschii species
0.00035847218433837647 ubiome Bacteroides sp. AR20 species
0.00036399076711135514 biomesight Prevotella veroralis species
0.0004027885146831193 ombre Ruoffia tabacinasalis species
0.0004377632720581113 ubiome Bacteroides eggerthii species
0.00046771960709851085 ubiome Actinomyces sp. ph3 species
0.00047120149126616477 ubiome Neisseriaceae family
0.00047385004025723987 biomesight Desulfofundulus genus
0.0004799085613827976 ombre Slackia piriformis species
0.00048367329234754033 ombre Rothia dentocariosa species
0.0005006851375400613 ombre Sedimentibacter hongkongensis species
0.0005027517306821112 ubiome Acholeplasmatales order
0.0005092244759576925 ombre Blautia stercoris species
0.0005125378684817971 ombre Spongiibacteraceae family
0.0005173657236817186 ubiome Christensenella hongkongensis species
0.0005772987349529944 ubiome Hoylesella timonensis species
0.0006696326273872425 ubiome Acetanaerobacterium genus
0.0006899421631806579 ubiome Neisseriales order
0.0007259246076904796 ombre Pseudodesulfovibrio genus
0.0008026603965270333 ombre Nevskiales order
0.0008293349148145348 ombre Campylobacter ureolyticus species
0.0008614581123558285 ubiome Schaalia genus
0.0008835116526415554 ombre Eubacterium pyruvativorans species
0.0008933545006313866 ombre [Clostridium] fimetarium species

Enzymes

Probability Lab Enzyme EC Key
1.5627867060525977E-07 biomesight 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) 1.3.1.75
2.973342118284427E-07 ombre D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphosphoundecaprenol 2-β-glucuronosyltransferase 2.4.1.264
3.672940351824393E-07 biomesight bacteriochlorophyllide d C-82-methyltransferase 2.1.1.332
3.672940351824393E-07 biomesight sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) 1.1.1.325
3.672940351824393E-07 biomesight bacteriochlorophyllide d C-20 methyltransferase 2.1.1.333
3.672940351824393E-07 biomesight bacteriochlorophyllide d C-121-methyltransferase 2.1.1.331
3.672940351824393E-07 biomesight 3-vinyl bacteriochlorophyllide d 31-hydratase 4.2.1.169
3.672940351824393E-07 biomesight chlorophyllide a hydrolase 3.1.1.100
1.8461771536052995E-06 biomesight ATP citrate synthase 2.3.3.8
3.0260321921429027E-06 biomesight geranylgeranylglycerol-phosphate geranylgeranyltransferase 2.5.1.42
4.659559356047167E-06 biomesight bacteriochlorophyllide c C-71-hydroxylase 1.17.98.2
1.2031391275906366E-05 biomesight 2-hydroxymuconate-6-semialdehyde hydrolase 3.7.1.9
1.8935456468138767E-05 ombre protein-disulfide reductase 1.8.1.8
2.3473121327550136E-05 ombre glutathione amide reductase 1.8.1.16
2.3473121327550136E-05 ombre glutathione amide-dependent peroxidase 1.11.1.17
3.405878583139945E-05 ombre polyvinyl alcohol dehydrogenase (cytochrome) 1.1.2.6
7.335179932820281E-05 ubiome inulosucrase 2.4.1.9
7.644605261702964E-05 ubiome superoxide reductase 1.15.1.2
9.601364738204769E-05 ubiome anthranilate 1,2-dioxygenase (deaminating, decarboxylating) 1.14.12.1
9.615342735181518E-05 ubiome indole-3-acetate monooxygenase 1.14.13.235
0.00011366484425945345 ubiome UDP-N-acetylglucosamine 3-dehydrogenase 1.1.1.374
0.00013840542666399003 ubiome cellobiose epimerase 5.1.3.11
0.00014661294759298047 ubiome hydroxyquinol 1,2-dioxygenase 1.13.11.37
0.00016116676069623796 ombre meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I 2.3.1.293
0.00016116676069623796 ombre meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II 2.3.1.294
0.00016506331528010065 ubiome phenylacetyl-CoA 1,2-epoxidase 1.14.13.149
0.000167340246167047 ubiome succinate-semialdehyde dehydrogenase (acylating) 1.2.1.76
0.00019272962922878278 ubiome 3-oxoacid CoA-transferase 2.8.3.5
0.0002012091774523923 biomesight Δ7-sterol 5(6)-desaturase 1.14.19.20
0.00020225644446281166 biomesight tRNA (adenine22-N1)-methyltransferase 2.1.1.217
0.0002226157187732447 ubiome formamidase 3.5.1.49
0.0002254925514855592 ombre pyridoxamine—pyruvate transaminase 2.6.1.30
0.00024040357895317876 biomesight (3S)-malyl-CoA thioesterase 3.1.2.30
0.00027485296782400715 ubiome phytanoyl-CoA dioxygenase 1.14.11.18
0.00027485296782400715 ubiome (methylthio)acryloyl-CoA hydratase 4.2.1.155
0.00029322373836326854 ubiome D-ribulokinase 2.7.1.47
0.00031856760378978777 ubiome precorrin-2 dehydrogenase 1.3.1.76
0.00032733103096216354 ubiome hydroxyisourate hydrolase 3.5.2.17
0.0003384821522999504 ubiome N-acetylphosphatidylethanolamine-hydrolysing phospholipase D 3.1.4.54
0.0003458183300519835 biomesight muconolactone Δ-isomerase 5.3.3.4
0.0003727735760126194 biomesight benzaldehyde dehydrogenase (NAD+) 1.2.1.28
0.0003742307892167229 ombre phosphatidylinositol-3-phosphatase 3.1.3.64
0.0003905486123817532 biomesight lysostaphin 3.4.24.75
0.0004018215982495299 ubiome acetoacetate decarboxylase 4.1.1.4
0.0004088458619812234 ubiome acylglycerol lipase 3.1.1.23
0.00041295055055544984 ubiome 3-(hydroxyamino)phenol mutase 5.4.4.3
0.0004377632720581113 ubiome glucan 1,6-α-isomaltosidase 3.2.1.94
0.0004377632720581113 ubiome UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol β-1,4-galactosyltransferase 2.4.1.304
0.0004377632720581113 ubiome CDP-abequose:α-L-Rha2OAc-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-α-D-Gal-PP-Und α-1,3-abequosyltransferase 2.4.1.382
0.0004377632720581113 ubiome 3-aminobutanoyl-CoA transaminase 2.6.1.111
0.0004377632720581113 ubiome dolichyl N-acetyl-α-D-glucosaminyl phosphate 3-β-D-2,3-diacetamido-2,3-dideoxy-β-D-glucuronosyltransferase 2.4.1.335
0.0004560623367317884 ombre hydroxymethylbilane synthase 2.5.1.61
0.0004641156214969732 biomesight N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase 1.5.1.51
0.0004657049171057359 ombre heme oxygenase (biliverdin-producing, ferredoxin) 1.14.15.20
0.0004700683112737244 biomesight (2S)-3-sulfopropanediol dehydratase 4.2.1.177
0.00048447870800738535 ombre sulfate adenylyltransferase (ADP) 2.7.7.5
0.0004895752317699898 ubiome thiopurine S-methyltransferase 2.1.1.67
0.0004914755456657538 biomesight L-lysine N6-monooxygenase (NADPH) 1.14.13.59
0.0004958856500724835 ubiome aliphatic aldoxime dehydratase 4.8.1.2
0.0005289327793418514 ombre endo-1,3(4)-β-glucanase 3.2.1.6
0.0005486067546458528 ombre ABC-type sulfate transporter 7.3.2.3
0.0005530617139442772 biomesight aureolysin 3.4.24.29
0.0005535413657127286 ubiome protein-Nπ-phosphohistidine—2-O-α-mannosyl-D-glycerate phosphotransferase 2.7.1.195
0.000558446535261492 ubiome heme o synthase 2.5.1.141
0.0005831363186414862 biomesight tryptophan 2,3-dioxygenase 1.13.11.11
0.0006250281243689644 ombre biliverdin reductase 1.3.1.24
0.0006526963997517399 ubiome glycerol-3-phosphate oxidase 1.1.3.21
0.0006619575163656127 ombre CDP-L-myo-inositol myo-inositolphosphotransferase 2.7.8.34
0.0006773823664594265 biomesight C5a peptidase 3.4.21.110
0.0006936671826003327 ombre N-acetyldiaminopimelate deacetylase 3.5.1.47
0.0007393477223258671 biomesight phytanoyl-CoA dioxygenase 1.14.11.18
0.0007439962165258773 biomesight 3-mercaptopropionate dioxygenase 1.13.11.91
0.0008439055166699295 ombre demethylspheroidene O-methyltransferase 2.1.1.210
0.000855896542313441 ombre mycobacterial β-ketoacyl-[acyl carrier protein] synthase III 2.3.1.301
0.0008569161559466298 ombre 2,4′-dihydroxyacetophenone dioxygenase 1.13.11.41
0.0008970779376753502 ombre 5-deoxy-glucuronate isomerase 5.3.1.30
0.000922298299557367 ombre 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase 1.3.1.87
0.0009410352053860205 biomesight formimidoylglutamate deiminase 3.5.3.13
0.0009664430489177978 ombre 3-phenylpropanoate dioxygenase 1.14.12.19
0.0009813329259264862 ombre L-galactose 1-dehydrogenase 1.1.1.316
0.0010566016127877553 biomesight choline monooxygenase 1.14.15.7
0.0010599135032631768 biomesight menaquinone C8-methyltransferase 2.1.1.350
0.0011224140737584598 ombre dye decolorizing peroxidase 1.11.1.19
0.001150680016709079 ombre aspartoacylase 3.5.1.15
0.0011745374329559244 ombre tellurite methyltransferase 2.1.1.265
0.0011924346830931582 ombre gingipain K 3.4.22.47
0.0011978164265242786 biomesight dehydrogluconokinase 2.7.1.13
0.001220671073931952 biomesight cellulose 1,4-β-cellobiosidase (non-reducing end) 3.2.1.91
0.001305792100055021 ombre phosphoenolpyruvate carboxykinase (diphosphate) 4.1.1.38
0.0013516852515884368 ombre 6-hydroxynicotinate 3-monooxygenase 1.14.13.114

Net Metabolites

Probability Lab Enzyme EC Key
2.220446049250313E-16 biomesight Oxalosuccinate C05379
2.220446049250313E-16 biomesight Lipoyl-AMP C16238
8.881784197001252E-16 biomesight Coenzyme F420-1 C19152
4.696909527979187E-12 biomesight 2-Dehydro-3-deoxy-6-phospho-D-galactonate C01286
1.3591794356671016E-11 biomesight Palmitoyl-[(hydroxy)phthioceranic acid synthase] C22124
2.4764326145287896E-09 ombre dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose C20415
4.276047738116517E-09 biomesight (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate C06321
1.3147121613599211E-08 ombre 2,3-Bisphospho-D-glycerate C01159
6.966528975915764E-08 ubiome Benzaldehyde C00261
4.7431040384182666E-07 biomesight cis-Aconitate C00417
7.689809455368823E-07 biomesight 8,12-Diethyl-3-vinylbacteriochlorophyllide d C21427
7.689809455368823E-07 biomesight 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d C21428
8.889700656995877E-06 biomesight Bacteriochlorophyllide c C18161
8.889700656995877E-06 biomesight 7-(Hydroxymethyl)bacteriochlorophyllide c C21407
8.889700656995877E-06 biomesight 7-(Dihydroxymethyl)bacteriochlorophyllide c C20650
2.9725153320114828E-05 ombre N(gamma)-Acetyldiaminobutyrate C06442
3.336291658562196E-05 ombre Enolpyruvoyl-2-diphospho-5'-guanosine C22297
3.336291658562196E-05 ombre (2S)-Lactyl-2-diphospho-5'-guanosine C19155
3.567286075267795E-05 biomesight N2-Succinyl-L-arginine C03296
8.935186098768533E-05 ubiome 5-O-(1-Carboxyvinyl)-3-phosphoshikimate C01269
8.944729176207922E-05 ombre [SoxY protein]-S-sulfosulfanyl-L-cysteine C21815
9.518471653024996E-05 biomesight alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C21780
0.00011953821168941836 ombre (L-Cysteinyl)adenylate C22385
0.00012559836794001633 biomesight Benzene-1,2,4-triol C02814
0.00016539782710545126 ubiome N-Acetyl-alpha-D-galactosamine 1-phosphate C18060
0.00027485296782400715 ubiome 3-Oxopropionyl-CoA C05989
0.00027485296782400715 ubiome 3-Hydroxy-3-(methylthio)propanoyl-CoA C20968
0.00031495436367512397 ubiome 3-Demethylubiquinol C21860
0.0003260771756574393 biomesight N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate C21559
0.00043230999111143475 biomesight UDP-L-Ara4FN C16154
0.00047104212097502814 biomesight L-2,3-Diaminopropanoate C03401
0.00047874205544573556 ubiome 2-Dehydro-3-deoxy-6-phospho-D-galactonate C01286
0.0004976207487099593 ubiome L-Aspartate 4-semialdehyde C00441
0.0005220280200251004 ombre D-Glyceraldehyde 3-phosphate C00118
0.0005507188059419299 ombre Polyphosphate C00404
0.0005698422001938486 ubiome Dehydroalanine C02218
0.0005698422001938486 ubiome Cobyrinate c-monamide C19724
0.0006255823024139505 ubiome 2,3-Dihydroxybenzoate C00196
0.0006568077595787702 ubiome Protoporphyrinogen IX C01079
0.0007413744175739367 biomesight 2-Dehydro-L-erythronate C21618
0.0008195213671964443 ubiome cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol C11588
0.0009692707444732861 biomesight Sterol C00370
0.0009692707444732861 biomesight Fatty acid C00162
0.0010456691390188233 ombre [SoxY protein]-S-sulfanyl-L-cysteine C21898
0.0010705668639108268 biomesight 3-Oxo-Delta5-steroid C01034
0.0010752613222790863 biomesight Carotenoid beta-end group C21915
0.0010831738731311785 biomesight Phylloquinone C02059
0.0010893851425069286 biomesight Dimethylamine C00543
0.0010992571366554849 biomesight D-Galacturonate C00333
0.0011037999730848906 biomesight 3,4-Didehydroadipyl-CoA semialdehyde C19683
0.0011240814412325495 biomesight 2,3-Diketo-5-methylthiopentyl-1-phosphate C15650
0.0011440916846714524 ubiome D-Tagatose C00795
0.001191560004085046 ubiome D-Glucose 6-phosphate C00092
0.0012280779920548549 ubiome N2-Succinyl-L-ornithine C03415
0.0012280779920548549 ubiome N2-Succinyl-L-arginine C03296
0.0012769609090655556 ombre 7,9,7',9'-tetracis-Lycopene C15858
0.0012769609090655556 ombre 7,9,9'-tricis-Neurosporene C19759
0.0012874515063894254 ombre N-Acyl-L-homoserine lactone C18049
0.001344256815234297 biomesight 2-(alpha-D-Mannosyl)-3-phosphoglycerate C11516
0.0013574608643135042 ombre (2S)-Methylsuccinyl-CoA C18324
0.0013923593395495093 ombre Urate C00366
0.0014433169775653898 biomesight N-Succinyl-L-glutamate C05931
0.0014473045503431425 ubiome 6-Hydroxymethyl-7,8-dihydropterin diphosphate C04807
0.0014691147041525632 ombre 1,4-Dihydroxy-2-naphthoyl-CoA C15547
0.001570217442266264 ombre cis-Aconitate C00417
0.0015776023272017384 ombre Ribonucleoside triphosphate C03802
0.0015850107848982553 ubiome (R)-4'-Phosphopantothenoyl-L-cysteine C04352
0.0015864163781870919 ombre 2-Phytyl-1,4-naphthoquinone C13309
0.0015872239590055681 ubiome Trimethylamine C00565
0.0016116030254316942 ombre Protein C00017
0.0016550426674935004 ombre Phosphoribosyl-AMP C02741
0.0016643392464608109 ombre N6-(1,2-Dicarboxyethyl)-AMP C03794
0.0016884605973170874 ubiome Acetyl-[acyl-carrier protein] C03939
0.001741113984332426 ubiome Dehydrospermidine C15853
0.001741113984332426 ubiome N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine C15854
0.0017552123725872448 ombre Pyridoxal C00250
0.0018085558093693327 ombre Protochlorophyllide C02880
0.001812044166098035 ubiome trans-2,3-Dihydroxycinnamate C12623
0.001812044166098035 ubiome 3-(2,3-Dihydroxyphenyl)propanoate C04044
0.0018218116612569446 ubiome Nitrate C00244
0.0018400655525297564 ubiome UDP-N,N'-diacetylbacillosamine C20357
0.0018787296855140578 ombre L-Cysteate C00506
0.0018848257532881885 ubiome 4-Hydroxy-3-polyprenylbenzoate C05848
0.0019265523201950074 ubiome D-glycero-beta-D-manno-Heptose 1,7-bisphosphate C11472
0.0019527414437721102 ombre UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine C22409
0.00197898526678264 ubiome alpha-D-Galactose 1-phosphate C00446
0.002062512695187646 ombre 4-Methylthio-2-oxobutanoic acid C01180
0.0021243824044458928 ombre (25S)-26-Oxocholest-4-en-3-one C21304
0.0021243824044458928 ombre (25S)-26-Hydroxycholest-4-en-3-one C20143
0.0021243824044458928 ombre Delta4-Dafachronic acid C21076

Metabolites Producers

Probability Lab Enzyme EC Key
7.689809455368823E-07 biomesight 3-Vinyl bacteriochlorophyllide d C21426
7.689809455368823E-07 biomesight 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d C21429
7.689809455368823E-07 biomesight Bacteriochlorophyllide c C18161
7.689809455368823E-07 biomesight 8,12-Diethyl-3-vinylbacteriochlorophyllide d C21427
7.689809455368823E-07 biomesight Sepiapterin C00835
7.689809455368823E-07 biomesight 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d C21428
8.889700656995877E-06 biomesight Bacteriochlorophyllide e C21582
8.889700656995877E-06 biomesight 7-(Hydroxymethyl)bacteriochlorophyllide c C21407
8.889700656995877E-06 biomesight 7-(Dihydroxymethyl)bacteriochlorophyllide c C20650
2.8592724459925816E-05 ombre Glutathione amide disulfide C19690
4.0791956143620445E-05 ombre Oxidized polyvinyl alcohol C01166
7.571003353468164E-05 ubiome Oxidized rubredoxin C00435
8.615457269556259E-05 biomesight 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol C06364
9.615342735181518E-05 ubiome (2-Hydroxy-1H-indol-3-yl)acetate C21619
0.00011366484425945345 ubiome UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose C20849
0.00013840542666399003 ubiome 4-O-beta-D-Glucopyranosyl-D-mannose C02964
0.00015867506227618122 ubiome 1-Pyrroline-2-carboxylate C03564
0.00016506331528010065 ubiome 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA C20062
0.00027485296782400715 ubiome 3-Hydroxy-3-(methylthio)propanoyl-CoA C20968
0.00027485296782400715 ubiome 3-Oxopropionyl-CoA C05989
0.00027485296782400715 ubiome 2-Hydroxyphytanoyl-CoA C07343
0.0003260771756574393 biomesight L-2,3-Diaminopropanoate C03401
0.00032733103096216354 ubiome 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate C12248
0.0003643457929878302 ombre cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol C11588
0.00041295055055544984 ubiome Aminohydroquinone C14604
0.0004377632720581113 ubiome Archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate C21213
0.0004377632720581113 ubiome beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol C20618
0.00045014730790260415 ombre Hydroxymethylbilane C01024
0.0004895752317699898 ubiome 6-Methylmercaptopurine C16614
0.0004958856500724835 ubiome Aliphatic nitrile C16072
0.0005535413657127286 ubiome 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate C16699
0.0005903130982712672 ubiome D-Xylonolactone C02266
0.0006593799149947621 ubiome 3-Oxoadipyl-CoA C02232
0.0006670178344259092 ubiome D-glycero-alpha-D-manno-Heptose 1-phosphate C19880
0.0006670178344259092 ubiome D-glycero-beta-D-manno-Heptose 1-phosphate C07838
0.0006696794325029565 biomesight N-Formyl-L-glutamate C01045
0.0006759770634554574 biomesight L-Formylkynurenine C02700
0.0006846424280671112 ubiome Methanesulfinic acid C21398
0.0006965260021517996 ubiome (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate C19831
0.0007184930699275505 biomesight 8-Methylmenaquinone C22027
0.0007184930699275505 biomesight 2-Demethyl-8-methylmenaquinone C22028
0.0007740158157296673 ombre 2-Deoxy-5-keto-D-gluconic acid C06892
0.0008195213671964443 ubiome cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol C11588
0.0008724320922781637 ombre 3-Sulfopyruvate C05528
0.0008728683906891394 ombre L-Galactono-1,4-lactone C01115
0.0009176110539859377 biomesight 3-Oxopropane-1-sulfonate C22384
0.0009201655852755231 ombre Biliverdin C00500
0.0009330648227530158 ombre 4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C21502
0.000969097058158841 biomesight 6-Methylmercaptopurine C16614
0.0009692707444732861 biomesight Sterol C00370
0.0009692707444732861 biomesight Fatty acid C00162
0.0009773623605094828 ombre Spheroidene C15900
0.0009903011755465485 ombre 2,5-Dihydroxybenzoate C00628
0.000997486579560114 ubiome Protein N(omega)-phospho-L-arginine C21101
0.0010122983637930183 ubiome Magnesium protoporphyrin C03516
0.001053252875821533 ubiome 5-Dehydro-D-fructose C00273
0.0010831738731311785 biomesight Vitamin K1 epoxide C05849
0.0010831738731311785 biomesight Phylloquinone C02059
0.0011169999573226175 ubiome Pseudaminic acid C20082
0.0011391349014249208 ubiome 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C21508
0.0011391349014249208 ubiome 4-O-[(1-D-Ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C21504
0.0011516215572135663 ubiome Alanine C01401
0.0012136741190878762 ombre Methyl acetate C17530
0.0012769609090655556 ombre 7,9,7',9'-tetracis-Lycopene C15858
0.0012769609090655556 ombre 7,9,9'-tricis-Neurosporene C19759
0.0013959874036433284 ombre alpha-Oxo-benzeneacetic acid C02137
0.001497361610391712 ombre Reduced FMN C01847
0.001521345872442159 ombre [5-(Aminomethyl)furan-3-yl]methyl diphosphate C21069
0.001532793367323337 ombre Androstenedione C00280
0.0015374528166096635 ombre Aminoacetaldehyde C06735
0.0015776023272017384 ombre Ribonucleoside triphosphate C03802
0.0015864163781870919 ombre 2-Phytyl-1,4-naphthoquinone C13309
0.0016116030254316942 ombre Protein C00017
0.0016219853761395952 ombre Carnitine C00487
0.0016374011245664335 biomesight 2-(alpha-D-Mannosyl)-3-phosphoglycerate C11516
0.0016669368957194532 biomesight (L-Arginyl)adenylate C22264
0.001678753320214721 biomesight 3-[(1-Carboxyvinyl)oxy]benzoate C20772
0.0017295739820986917 ombre 2-Oxo-3-(phosphooxy)propyl 3-oxoalkanoate C22065
0.00173955650979285 ombre Pyocyanine C01748
0.0017937842422578105 biomesight 1-Phosphatidyl-1D-myo-inositol 5-phosphate C11557
0.0018004261153172774 biomesight Raffinose C00492
0.0018063252065111256 ombre L-Galactose C01825
0.0018161970286894036 ombre 1-Archaetidyl-1D-myo-inositol 3-phosphate C20642
0.0018333853634620173 biomesight Bacteriochlorophyllide a C18155
0.0018333853634620173 biomesight 1-Hydroxy-1,2-dihydrolycopene C19795
0.0018333853634620173 biomesight Divinyl chlorophyllide a C11832
0.0018333853634620173 biomesight 3-Hydroxyethylchlorophyllide a C18154
0.0019383947868405471 ombre 5-Hydroxyectoine C16432
0.0020154256778071034 ombre Protein N5-alkylglutamine C03636
0.0020347577178729814 ombre Carotenoid phi-end group C21916

Metabolites Substrate / Consumer

Probability Lab Enzyme EC Key
1.3633538742396922E-13 biomesight 2-Dehydro-3-deoxy-D-glucarate C03921
7.689809455368823E-07 biomesight L-threo-7,8-Dihydrobiopterin C20263
7.689809455368823E-07 biomesight 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d C21428
7.689809455368823E-07 biomesight L-threo-Tetrahydrobiopterin C20264
7.689809455368823E-07 biomesight 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d C18157
7.689809455368823E-07 biomesight Bacteriochlorophyllide d C18160
7.689809455368823E-07 biomesight 8,12-Diethyl-3-vinylbacteriochlorophyllide d C21427
3.268989132054756E-06 ombre Protein glutamine C02583
5.814038246221436E-06 biomesight 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate C04590
8.889700656995877E-06 biomesight Bacteriochlorophyllide c C18161
8.889700656995877E-06 biomesight 7-(Hydroxymethyl)bacteriochlorophyllide c C21407
8.889700656995877E-06 biomesight 7-(Dihydroxymethyl)bacteriochlorophyllide c C20650
2.8592724459925816E-05 ombre Glutathione amide C19689
4.0791956143620445E-05 ombre Polyvinyl alcohol C00980
4.0880006952459524E-05 biomesight 3-Oxoadipate C00846
7.571003353468164E-05 ubiome Reduced rubredoxin C00340
7.780561172660491E-05 ubiome Indole-3-acetate C00954
0.00011863126984241497 ubiome (S)-Mandelate C01984
0.00014661294759298047 ubiome Benzene-1,2,4-triol C02814
0.00016506331528010065 ubiome Phenylacetyl-CoA C00582
0.00019272962922878278 ubiome 3-Oxo acid C01656
0.0002226157187732447 ubiome Formamide C00488
0.0002571536290355947 ombre Pyridoxamine C00534
0.00027485296782400715 ubiome 3-Oxopropionyl-CoA C05989
0.00027485296782400715 ubiome 3-Hydroxy-3-(methylthio)propanoyl-CoA C20968
0.00027485296782400715 ubiome Phytanoyl-CoA C02060
0.00027485296782400715 ubiome 3-(Methylthio)acryloyl-CoA C20955
0.0003260771756574393 biomesight N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate C21559
0.00032733103096216354 ubiome 5-Hydroxyisourate C11821
0.0003506264423231986 ombre cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol C12622
0.0003506264423231986 ombre cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol C11588
0.0003643457929878302 ombre Phenylpropanoate C05629
0.0003643457929878302 ombre trans-Cinnamate C00423
0.0003721643386629392 ombre 1-Phosphatidyl-1D-myo-inositol 3-phosphate C04549
0.00041295055055544984 ubiome 3-Hydroxyaminophenol C14602
0.0004377632720581113 ubiome Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate C04678
0.0004377632720581113 ubiome 3-Aminobutanoyl-CoA C05117
0.00045014730790260415 ombre Porphobilinogen C00931
0.00047693679332661 ombre Aniline C00292
0.0004895752317699898 ubiome Thiopurine C01756
0.0004958856500724835 ubiome Aldoxime C02658
0.0005072696824477418 biomesight Benzaldehyde C00261
0.0005349545441270569 ubiome CDP-abequose C01788
0.000570292145330056 ombre Bilirubin C00486
0.0005903130982712672 ubiome D-Xylose C00181
0.0006442486232767219 ombre 3-Hydroxybenzoate C00587
0.0006670178344259092 ubiome D-glycero-beta-D-manno-Heptose 1,7-bisphosphate C11472
0.0006670178344259092 ubiome D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate C19879
0.0006846424280671112 ubiome Dimethyl sulfone C11142
0.0007184930699275505 biomesight 2-Demethylmenaquinone C05818
0.0007210187904315399 ubiome 4-Hydroxyphenacyl alcohol C13635
0.0007477328313350018 ombre N6-Acetyl-LL-2,6-diaminoheptanedioate C04390
0.0007740158157296673 ombre 5-Deoxy-D-glucuronate C16737
0.0008195213671964443 ubiome cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol C11588
0.0008195213671964443 ubiome cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol C12622
0.0008195213671964443 ubiome trans-Cinnamate C00423
0.0008728683906891394 ombre L-Galactose C01825
0.0009460974384920551 ubiome N-Acyl-D-mannosamine C00625
0.000969097058158841 biomesight Thiopurine C01756
0.0009692707444732861 biomesight Steryl ester C01958
0.0009773623605094828 ombre Demethylspheroidene C15898
0.0009786791370094416 biomesight Methanol C00132
0.000997486579560114 ubiome Protein-L-arginine C00613
0.0010122983637930183 ubiome Protoporphyrin C02191
0.0010122983637930183 ubiome Magnesium cation C00305
0.0010831738731311785 biomesight Phylloquinone C02059
0.0010831738731311785 biomesight Phylloquinol C03313
0.0012138661136245066 biomesight Cholest-4-en-3-one C00599
0.0012769609090655556 ombre 9,9'-dicis-zeta-Carotene C15857
0.0012769609090655556 ombre 7,9,9'-tricis-Neurosporene C19759
0.0013030677895971203 ombre N-Acyl-L-aspartate C02715
0.0014701082029424661 ombre Hippurate C01586
0.0015032265052532523 biomesight Ethanol C00469
0.001521345872442159 ombre [5-(Aminomethyl)furan-3-yl]methyl phosphate C21068
0.001532793367323337 ombre Testosterone C00535
0.001572479968035001 ombre 4-Hydroxyphenacyl alcohol C13635
0.0015864163781870919 ombre hn C00205
0.0015864163781870919 ombre 2-Carboxy-1,4-naphthoquinone C22039
0.0015864163781870919 ombre (3Z)-Phycocyanobilin C05786
0.0016219853761395952 ombre 4-Trimethylammoniobutanoate C01181
0.0016322737814433719 ombre CDP-3,6-dideoxy-D-glucose C03598
0.0016669368957194532 biomesight (L-Arginyl)adenylate C22264
0.001694992886261737 ombre Nicotinamide C00153
0.0017057495784222887 biomesight [SoxY protein]-S-disulfanyl-L-cysteine C21814
0.0017937842422578105 biomesight 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate C04637
0.0018004261153172774 biomesight alpha-D-Galactosyl-(1->3)-1D-myo-inositol C01235
0.0018333853634620173 biomesight Bacteriochlorophyllide g C21441
0.0018333853634620173 biomesight 3-Vinylbacteriochlorophyllide a C18152
0.0018333853634620173 biomesight 3-Hydroxyethylchlorophyllide a C18154
0.0018333853634620173 biomesight 3-Hydroxyethylbacteriochlorophyllide a C18153

Items Reported From All Labs

Bacteria

Bacteria Rank

Enzymes

Enzyme EC Key

Net Metabolites

Enzyme EC Key
(E)-4-(Trimethylammonio)but-2-enoyl-CoA C20748
[eIF5A-precursor]-lysine C07281
1,2-Diacyl-sn-glycerol C00641
1,4-Dihydroxy-2-naphthoate C03657
2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol C21607
2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol C21609
2-Polyprenylphenol C05807
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate C20934
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol C11435
4-Amino-4-deoxychorismate C11355
4-O-{Poly[(2R)-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C22411
6-Hydroxymethyl-7,8-dihydropterin diphosphate C04807
8-Oxo-dGDP C20176
8-Oxo-GDP C22235
CDP-diacylglycerol C00269
CDP-glycerol C00513
Choline C00114
Coenzyme F420 C00876
Dehypoxanthine futalosine C17010
D-Glucosamine C00329
D-Mannose 1-phosphate C00636
D-Ribose C00121
FMN C00061
Futalosine C16999
Galactosylceramide C02686
Holo-[citrate (pro-3S)-lyase] C04298
Indole C00463
Isochorismate C00885
L-Ornithine C00077
Protochlorophyllide C02880
Reduced coenzyme F420 C01080
Retinol C00473
RNA C00046
S-Methyl-5-thio-D-ribose 1-phosphate C04188
S-Ribosyl-L-homocysteine C03539
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate C19725
Xanthosine 5'-phosphate C00655

Metabolites Producers

Enzyme EC Key
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine C15977
[Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine C16254
[eIF5A-precursor]-deoxyhypusine C07282
[eIF5A-precursor]-lysine C07281
1,3-Diaminopropane C00986
1,5-Anhydro-D-fructose C06485
2,5-Didehydro-D-gluconate C02780
2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol C21607
2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol C21608
2-Polyprenylphenol C05807
3-[(1-Carboxyvinyl)oxy]benzoate C20772
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate C20934
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate C21383
3-Phosphonopyruvate C02798
4-Hydroxy-3-polyprenylbenzoate C05848
4-O-{Poly[(2R)-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C22411
4-O-beta-D-Glucopyranosyl-D-mannose C02964
5-Oxoprolyl-peptide C02805
6-Acetyl-beta-D-galactoside C03773
6-Amino-6-deoxyfutalosine C20773
7,8-Diaminononanoate C01037
Adenosine C00212
alpha-D-Mannose C00936
Aminoacetone C01888
beta-1,2-Mannobiose C21336
beta-D-Glucose 1-phosphate C00663
Choline C00114
CMP-N,N'-diacetyllegionaminate C20419
Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide C04832
Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} C22216
Deacetylcephalosporin C C03112
Dehydrospermidine C15853
Dehypoxanthine futalosine C17010
D-Galactose 6-phosphate C01113
D-Glucosamine C00329
D-Glucosamine 6-phosphate C00352
D-Glycerate C00258
Dimethylarsinous acid C20300
D-myo-Inositol 1,2-cyclic phosphate C04299
Dolichyl diphosphate C00621
D-Tagatose 6-phosphate C01097
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose C11930
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose C06620
Ferrocytochrome c C00126
Formyl-CoA C00798
Futalosine C16999
Galactosylceramide C02686
Heparan sulfate N-acetyl-alpha-D-glucosaminide C04649
Hydrogen C00282
L-Leucyl-L-aspartyl-protein C21457
L-Leucyl-L-glutamyl-protein C21455
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine C15854
N-[(7,8-Dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate C20562
Pantetheine 4'-phosphate C01134
Phosphatidylglycerol C00344
Plastoquinol-9 C16695
Protein N6-acetyl-L-lysine C20743
Reduced hydrogenase C22336
S-Adenosyl-4-methylthio-2-oxobutanoate C04425
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate C19725
UDP-alpha-D-galactofuranose C03733
UDP-alpha-D-galactose C00052
UDP-N,N'-diacetylbacillosamine C20357

Metabolites Substrate / Consumer

Enzyme EC Key
[eIF5A-precursor]-lysine C07281
1,2-beta-Oligomannan C21335
1,5-Anhydro-D-mannitol C16538
1-Phosphatidyl-D-myo-inositol C01194
2-Hydroxyethylphosphonate C06451
2-Methyl-6-phytylquinol C15882
2-Methyl-6-solanyl-1,4-benzoquinol C17570
2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol C21609
3-[(1-Carboxyvinyl)oxy]benzoate C20772
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate C21383
4-(beta-D-Ribofuranosyl)aniline 5'-phosphate C20559
4-Hydroxy-3-polyprenylbenzoate C05848
6-Amino-6-deoxyfutalosine C20773
6-Geranylgeranyl-2-methylbenzene-1,4-diol C20737
6-Phospho-beta-D-galactoside C03847
8-Amino-7-oxononanoate C01092
ADP-ribose C00301
beta-1,2-Mannobiose C21336
beta-1,2-Mannotriose C21454
beta-D-Galactoside C00602
CDP-glycerol C00513
Cephalosporin C C00916
Choline sulfate C00919
Coenzyme B C04628
Coenzyme M C03576
Dehydrospermidine C15853
Dehypoxanthine futalosine C17010
D-Fructose C00095
D-Galactose 6-phosphate C01113
D-Lyxose C00476
Dolichyl diphosphooligosaccharide C04213
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose C11930
dTDP-4-oxo-2,6-dideoxy-D-glucose C11922
Ethanolamine C00189
Ferricytochrome c C00125
Formyl-CoA C00798
Glycerol C00116
Heparan sulfate alpha-D-glucosaminide C04384
Hydroxypyruvate C00168
Icosanoyl-[(phenol)carboxyphthiodiolenone synthase] C22226
L-2-Amino-3-oxobutanoic acid C03508
L-Aspartyl-protein C21458
L-Glutaminyl-peptide C02986
L-Glutamyl-protein C21456
L-Ornithine C00077
Methyl acetate C17530
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine C15854
N,N'-Diacetyllegionaminate C20418
N-Sulfo-D-glucosamine C01075
Oxalyl-CoA C00313
Oxidized hydrogenase C22335
Phosphatidylglycerophosphate C03892
Polysulfide C19692
Protein lysine C02188
Pyridoxamine phosphate C00647
Pyridoxine phosphate C00627
Reduced FMN C01847
scyllo-Inositol C06153
Sulfatide C06125
tritrans,heptacis-Undecaprenyl phosphate C20420
UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate C20359
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose C04630
UDP-alpha-D-galactose C00052
Xylitol C00379

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