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Partial list of Citations used for Recommendations or Conditions

Recent additions may not be included but will usually appear in 24 hrs or less.

Rational Source
The role of short-chain fatty acids in microbiota-gut-brain communication. ✅ Go to Publication ✅
Nature reviews. Gastroenterology & hepatology (Nat Rev Gastroenterol Hepatol ) Vol: 16 Issue 8 Pages: 461-478
Pub: 2019 Aug Epub: Authors Dalile B , Van Oudenhove L , Vervliet B , Verbeke K ,
Impacts of Habitual Diets Intake on Gut Microbial Counts in Healthy Japanese Adults. ✅
Nutrients (Nutrients ) Vol: 12 Issue 8 Pages:
Pub: 2020 Aug 12 Epub: 2020 Aug 12 Authors Sugimoto T , Shima T , Amamoto R , Kaga C , Kado Y , Watanabe O , Shiinoki J , Iwazaki K , Shigemura H , Tsuji H , Matsumoto S ,
Effect of fucoidan on ethanol-induced liver injury and steatosis in mice and the underlying mechanism. ✅ Go to Publication ✅
Food & nutrition research (Food Nutr Res ) Vol: 65 Issue Pages:
Pub: 2021 Epub: 2021 Apr 20 Authors Xue M , Liang H , Zhou Z , Liu Y , He X , Zhang Z , Sun T , Yang J , Qin Y , Qin K ,
Dietary fucoidan of Acaudina molpadioides alters gut microbiota and mitigates intestinal mucosal injury induced by cyclophosphamide. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 8 Issue 9 Pages: 3383-3393
Pub: 2017 Sep 20 Epub: Authors Shi H , Chang Y , Gao Y , Wang X , Chen X , Wang Y , Xue C , Tang Q ,
Dietary fucoidan of Acaudina molpadioides alters gut microbiota and mitigates intestinal mucosal injury induced by cyclophosphamide. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 8 Issue 9 Pages: 3383-3393
Pub: 2017 Sep 20 Epub: Authors Shi H , Chang Y , Gao Y , Wang X , Chen X , Wang Y , Xue C , Tang Q ,
Effects of seaweed extracts on in vitro rumen fermentation characteristics, methane production, and microbial abundance. ✅ Go to Publication ✅
Scientific reports (Sci Rep ) Vol: 11 Issue 1 Pages: 24092
Pub: 2021 Dec 16 Epub: 2021 Dec 16 Authors Choi Y , Lee SJ , Kim HS , Eom JS , Jo SU , Guan LL , Seo J , Kim H , Lee SS , Lee SS ,
Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. ✅
Applied and environmental microbiology (Appl Environ Microbiol ) Vol: 34 Issue 5 Pages: 529-33
Pub: 1977 Nov Epub: Authors Salyers AA , West SE , Vercellotti JR , Wilkins TD ,
Study on Immunoregulatory Effects of Fucoidan from Sargassum graminifolium In Vivo and Immunoactivation Activity of Its Fecal Fermentation Products Using Co-Culture Model. ✅ Go to Publication ✅
Molecules (Basel, Switzerland) (Molecules ) Vol: 28 Issue 23 Pages:
Pub: 2023 Nov 27 Epub: 2023 Nov 27 Authors Wang C , Huang L , Huang Y , Tian X , Liu J ,
Study on Immunoregulatory Effects of Fucoidan from Sargassum graminifolium In Vivo and Immunoactivation Activity of Its Fecal Fermentation Products Using Co-Culture Model. ✅ Go to Publication ✅
Molecules (Basel, Switzerland) (Molecules ) Vol: 28 Issue 23 Pages:
Pub: 2023 Nov 27 Epub: 2023 Nov 27 Authors Wang C , Huang L , Huang Y , Tian X , Liu J ,
Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice. ✅ Go to Publication ✅
Nutrition research (New York, N.Y.) (Nutr Res ) Vol: 122 Issue Pages: 1-18
Pub: 2024 Feb Epub: 2023 Nov 17 Authors Li S , Qian Q , Yang H , Wu Z , Xie Y , Yin Y , Cui Y , Li X ,
A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways. ✅ Go to Publication ✅
Pharmaceuticals (Basel, Switzerland) (Pharmaceuticals (Basel) ) Vol: 16 Issue 3 Pages:
Pub: 2023 Mar 20 Epub: 2023 Mar 20 Authors He S , Peng WB , Zhou HL , Fu XJ , Sun YH , Wang ZG ,
Metagenomic Insights into the Anti-Obesity Effect of a Polysaccharide from Saccharina japonica. ✅ Go to Publication ✅
Foods (Basel, Switzerland) (Foods ) Vol: 12 Issue 3 Pages:
Pub: 2023 Feb 3 Epub: 2023 Feb 3 Authors Song Y , Lu D , Wang H , Zhou Z , Luo X , Ma M , Ke S , Wang H , Yu Y , Wei B ,
Bioactive polysaccharides promote gut immunity via different ways. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 14 Issue 3 Pages: 1387-1400
Pub: 2023 Feb 6 Epub: 2023 Feb 6 Authors Wu X , Huang X , Ma W , Li M , Wen J , Chen C , Liu L , Nie S ,
Fucoidan Ameliorated Dextran Sulfate Sodium-Induced Ulcerative Colitis by Modulating Gut Microbiota and Bile Acid Metabolism. ✅ Go to Publication ✅
Journal of agricultural and food chemistry (J Agric Food Chem ) Vol: 70 Issue 47 Pages: 14864-14876
Pub: 2022 Nov 30 Epub: 2022 Nov 15 Authors Liu X , Zhang Y , Li W , Zhang B , Yin J , Liuqi S , Wang J , Peng B , Wang S ,
Sargassum fusiforme fucoidan modifies gut microbiota and intestinal metabolites during alleviation of hyperglycemia in type 2 diabetic mice. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 12 Issue 8 Pages: 3572-3585
Pub: 2021 Apr 26 Epub: Authors Wu Q , Wu S , Cheng Y , Zhang Z , Mao G , Li S , Yang Y , Zhang X , Wu M , Tong H ,
Sargassum fusiforme fucoidan modifies gut microbiota and intestinal metabolites during alleviation of hyperglycemia in type 2 diabetic mice. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 12 Issue 8 Pages: 3572-3585
Pub: 2021 Apr 26 Epub: Authors Wu Q , Wu S , Cheng Y , Zhang Z , Mao G , Li S , Yang Y , Zhang X , Wu M , Tong H ,
Correction: Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 9 Issue 1 Pages: 655
Pub: 2018 Jan 24 Epub: Authors Shang Q , Shan X , Cai C , Hao J , Li G , Yu G ,
Correction: Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 9 Issue 1 Pages: 655
Pub: 2018 Jan 24 Epub: Authors Shang Q , Shan X , Cai C , Hao J , Li G , Yu G ,
Correction: Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae. ✅ Go to Publication ✅
Food & function (Food Funct ) Vol: 9 Issue 1 Pages: 655
Pub: 2018 Jan 24 Epub: Authors Shang Q , Shan X , Cai C , Hao J , Li G , Yu G ,
The Effect of Increasing Inclusion Levels of a Fucoidan-Rich Extract Derived from Ascophyllum nodosum on Growth Performance and Aspects of Intestinal Health of Pigs Post-Weaning. ✅ Go to Publication ✅
Marine drugs (Mar Drugs ) Vol: 17 Issue 12 Pages:
Pub: 2019 Nov 30 Epub: 2019 Nov 30 Authors Rattigan R , Sweeney T , Vigors S , Thornton K , Rajauria G , O'Doherty AJV ,
The Effect of Increasing Inclusion Levels of a Fucoidan-Rich Extract Derived from Ascophyllum nodosum on Growth Performance and Aspects of Intestinal Health of Pigs Post-Weaning. ✅ Go to Publication ✅
Marine drugs (Mar Drugs ) Vol: 17 Issue 12 Pages:
Pub: 2019 Nov 30 Epub: 2019 Nov 30 Authors Rattigan R , Sweeney T , Vigors S , Thornton K , Rajauria G , O'Doherty AJV ,
The Effect of Increasing Inclusion Levels of a Fucoidan-Rich Extract Derived from Ascophyllum nodosum on Growth Performance and Aspects of Intestinal Health of Pigs Post-Weaning. ✅ Go to Publication ✅
Marine drugs (Mar Drugs ) Vol: 17 Issue 12 Pages:
Pub: 2019 Nov 30 Epub: 2019 Nov 30 Authors Rattigan R , Sweeney T , Vigors S , Thornton K , Rajauria G , O'Doherty AJV ,
Effect of maternal seaweed extract supplementation on suckling piglet growth, humoral immunity, selected microflora, and immune response after an ex vivo lipopolysaccharide challenge. ✅ Go to Publication ✅
Journal of animal science (J Anim Sci ) Vol: 90 Issue 2 Pages: 505-14
Pub: 2012 Feb Epub: 2011 Sep 23 Authors Leonard SG , Sweeney T , Bahar B , O'Doherty JV ,
In vitro fermentation characteristics of fucoidan and its regulatory effects on human gut microbiota and metabolites. ✅ Go to Publication ✅
Food chemistry (Food Chem ) Vol: 465 Issue Pt 1 Pages: 141998
Pub: 2024 Nov 12 Epub: 2024 Nov 12 Authors Zhou X , Zhang Y , Wei L , Yang Y , Wang B , Liu C , Bai J , Wang C ,
Exploring the prebiotic potential of hydrolyzed fucoidan fermented in vitro with human fecal inocula: Impact on microbiota and metabolome. ✅ Go to Publication ✅
International journal of biological macromolecules (Int J Biol Macromol ) Vol: 267 Issue Pt 1 Pages: 131202
Pub: 2024 May Epub: 2024 Mar 29 Authors Huang X , Nie S , Fu X , Nan S , Ren X , Li R ,
Mitigation of Memory Impairment with Fermented Fucoidan and ?-Carrageenan Supplementation through Modulating the Gut Microbiota and Their Metagenome Function in Hippocampal Amyloid-ß Infused Rats. ✅ Go to Publication ✅
Cells (Cells ) Vol: 11 Issue 15 Pages:
Pub: 2022 Jul 26 Epub: 2022 Jul 26 Authors Zhang T , Wu X , Yuan H , Huang S , Park S ,
Modulation of Gene Expression in a Sterile Atopic Dermatitis Model and Inhibition of Staphylococcus aureus Adhesion by Fucoidan. ✅ Go to Publication ✅
Dermatopathology (Basel, Switzerland) (Dermatopathology (Basel) ) Vol: 8 Issue 2 Pages: 69-83
Pub: 2021 Mar 25 Epub: 2021 Mar 25 Authors Park AY , Bourtembourg M , Chrétien A , Hubaux R , Lancelot C , Salmon M , Fitton JH ,
Effect of dietary laminarin and fucoidan on selected microbiota, intestinal morphology and immune status of the newly weaned pig. ✅ Go to Publication ✅
The British journal of nutrition (Br J Nutr ) Vol: 110 Issue 9 Pages: 1630-8
Pub: 2013 Nov 14 Epub: 2013 Mar 26 Authors Walsh AM , Sweeney T , O'Shea CJ , Doyle DN , O'Doherty JV ,
The effect of dietary laminarin and fucoidan in the diet of the weanling piglet on performance, selected faecal microbial populations and volatile fatty acid concentrations. ✅ Go to Publication ✅
Animal : an international journal of animal bioscience (Animal ) Vol: 4 Issue 4 Pages: 579-85
Pub: 2010 Apr Epub: Authors McDonnell P , Figat S , O'Doherty JV ,
Fucoidan from Undaria pinnatifida Enhances Exercise Performance and Increases the Abundance of Beneficial Gut Bacteria in Mice. ✅ Go to Publication ✅
Marine drugs (Mar Drugs ) Vol: 22 Issue 11 Pages:
Pub: 2024 Oct 29 Epub: 2024 Oct 29 Authors Yang C , Dwan C , Wimmer BC , Wilson R , Johnson L , Caruso V ,
A low molecular weight fucoidan with high sulfation has anti-obesity activity via gut microbiota regulation. ✅ Go to Publication ✅
Carbohydrate polymers (Carbohydr Polym ) Vol: 364 Issue Pages: 123739
Pub: 2025 Sep 15 Epub: 2025 May 15 Authors Yu Y , Zhao Y , Wang H , Hua Y , Yu W , Wang N , Wei B , Wang H ,

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