Plasmodium fragile Details: NCBI 5857, gram-negative or unknown [species]

1. Severe Malaria: Plasmodium knowlesi infection can result in severe malaria, characterized by high fever, chills, sweating, headache, nausea, vomiting, muscle pain, and weakness. Severe cases may progress rapidly and lead to complications such as organ dysfunction, metabolic acidosis, respiratory distress, and cerebral malaria.

2. Cerebral Malaria: Plasmodium knowlesi infections can cause cerebral malaria, a severe complication characterized by altered consciousness, seizures, coma, and neurological deficits. Cerebral malaria can lead to long-term neurological sequelae or death if not promptly treated.

3. Anemia: Plasmodium knowlesi infection can cause hemolysis (destruction of red blood cells), leading to anemia. Severe anemia can result in fatigue, weakness, shortness of breath, and other complications.

4. Organ Dysfunction: Severe malaria caused by Plasmodium knowlesi can lead to dysfunction of vital organs such as the brain, kidneys, liver, and lungs. This can result in acute kidney injury, liver dysfunction, acute respiratory distress syndrome (ARDS), and other complications.

5. Pregnancy Complications: Plasmodium knowlesi infection during pregnancy can lead to adverse outcomes for both the mother and the baby, including maternal anemia, low birth weight, preterm birth, and stillbirth.

6. Immune Suppression: Malaria caused by Plasmodium knowlesi can suppress the host immune response, making individuals more susceptible to secondary infections and reducing the effectiveness of vaccines and other immune-mediated interventions.

7. Long-Term Effects: Survivors of severe malaria caused by Plasmodium knowlesi may experience long-term neurological sequelae such as cognitive impairment, epilepsy, and developmental delays.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

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General Substance	Specific Substance	Effect
Antibiotics, Antivirals etc	8-aminoquinoline analogue of primaquine {Tafenoquine}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Artemisia absinthium {wormwood}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium longum {B.Longum }	1 Studies recorded. The consensus is Decreases📓, Click for details.