Plasmodium malariae Details: NCBI 5858, gram-negative or unknown [species]

1. Chronic Infection: Plasmodium malariae infections tend to persist for long periods, sometimes even decades, if not treated. This chronicity can lead to ongoing health issues and complications.

2. Mild Malaria Symptoms: Plasmodium malariae infections often present with milder symptoms compared to other malaria species, such as Plasmodium falciparum. Symptoms may include fever, chills, headache, fatigue, muscle aches, and gastrointestinal disturbances. However, even though symptoms may be mild, the infection can persist for years if untreated.

3. Splenomegaly: In some cases, Plasmodium malariae infections can lead to enlargement of the spleen (splenomegaly), which may cause discomfort or pain in the left upper abdomen.

4. Nephrotic Syndrome: Plasmodium malariae infection has been associated with a kidney condition known as nephrotic syndrome, characterized by proteinuria (excretion of large amounts of protein in the urine), hypoalbuminemia (low levels of albumin in the blood), edema (swelling), and hyperlipidemia (elevated levels of lipids in the blood). This condition can lead to kidney damage if left untreated.

5. Long-Term Health Complications: Chronic Plasmodium malariae infections can lead to long-term health complications, including anemia, organ damage (especially to the kidneys), and potentially severe outcomes if the infection remains untreated for many years.

6. Potential for Recurrent Infections: Plasmodium malariae infections can recur over time, causing episodes of malaria in individuals who have been previously infected. These recurrent infections may contribute to ongoing health issues and exacerbate the risk of complications.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Plasmodium malariae

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.

External Reference Ranges for Plasmodium malariae

Plasmodium malariae (NCBI 5858) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	3.821787322522141E-05	0.00013986903650220484	0	0

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Antibiotics, Antivirals etc	8-aminoquinoline analogue of primaquine {Tafenoquine}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Artemisia absinthium {wormwood}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium longum {B.Longum }	1 Studies recorded. The consensus is Decreases📓, Click for details.