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Hypertension (High Blood Pressure): Ramipril is effective in lowering blood pressure by relaxing blood vessels, which allows blood to flow more easily. This helps reduce the risk of heart attacks, strokes, and kidney problems associated with hypertension.
Heart Failure: Ramipril is used to treat heart failure by reducing the workload on the heart and improving its function. It helps prevent the progression of heart failure and reduces symptoms such as shortness of breath and swelling.
Post-Myocardial Infarction (Heart Attack) Treatment: Ramipril is prescribed after a heart attack to improve survival and reduce the risk of future heart attacks, strokes, and related cardiovascular events. It helps prevent further damage to the heart and promotes healing.
Diabetic Nephropathy: Ramipril is used to delay the progression of diabetic nephropathy, a type of kidney disease that occurs in people with diabetes. It helps protect the kidneys by lowering blood pressure and reducing stress on the kidney filters (glomeruli).
Chronic Kidney Disease: Ramipril may be used to slow the progression of chronic kidney disease, especially in patients with proteinuria (excess protein in the urine). It helps protect the kidneys by lowering blood pressure and reducing strain on the kidneys.
Cardiovascular Protection: Ramipril provides cardiovascular protection by reducing the risk of cardiovascular events such as heart attacks, strokes, and peripheral artery disease. It helps improve blood flow and decrease the risk of blood clots.
Left Ventricular Dysfunction: Ramipril is used to improve outcomes in patients with left ventricular dysfunction, which is a condition where the left side of the heart is unable to pump blood effectively. It helps reduce symptoms and improve heart function.
Prevention of Stroke: Ramipril may be used to prevent strokes in certain high-risk patients, such as those with a history of stroke or transient ischemic attack (TIA). It helps lower blood pressure and improve blood flow to the brain, reducing the risk of stroke.
Coronary Artery Disease: Ramipril may be used as part of the treatment for coronary artery disease to reduce the risk of cardiovascular events and improve outcomes. It helps relax blood vessels and improve blood flow to the heart muscle.
Overall Cardiovascular Health: Ramipril is beneficial for overall cardiovascular health by lowering blood pressure, reducing strain on the heart, and improving blood flow throughout the body. It helps decrease the risk of cardiovascular events and mortality in patients with cardiovascular disease.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Bacteroides uniformis | Reduces |
| species | Parabacteroides distasonis | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| 📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 0 | 1 | Parabacteroides | genus | Decreases |
| 0 | 1 | Bacteroides | genus | Decreases |
| 0 | 1 | Thomasclavelia | genus | Decreases |
| 1 | 0 | Thomasclavelia ramosa | species | Decreases |
| 1 | 0 | Parabacteroides distasonis | species | Decreases |
| 1 | 0 | Bacteroides uniformis | species | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Acne | 0.3 | 0.3 | |
| ADHD | 0.5 | 0.5 | |
| Age-Related Macular Degeneration and Glaucoma | 0.4 | -0.4 | |
| Allergic Rhinitis (Hay Fever) | 0.7 | 0.7 | |
| Allergies | 0.4 | 0.3 | 0.33 |
| Allergy to milk products | 0.3 | 0.7 | -1.33 |
| Alopecia (Hair Loss) | 0.1 | 0.1 | |
| Alzheimer's disease | 0.8 | 0.3 | 1.67 |
| Ankylosing spondylitis | 0.4 | 0.3 | 0.33 |
| Anorexia Nervosa | 0.4 | 0.3 | 0.33 |
| Asthma | 0.3 | 0.3 | 0 |
| Atherosclerosis | 0.3 | 0.3 | |
| Atrial fibrillation | 0.7 | 0.7 | 0 |
| Autism | 0.7 | 0.8 | -0.14 |
| benign prostatic hyperplasia | 0.3 | -0.3 | |
| Bipolar Disorder | 0.7 | 0.7 | |
| Brain Trauma | 0.3 | -0.3 | |
| Carcinoma | 0.7 | 0.7 | 0 |
| Celiac Disease | 0.3 | 0.7 | -1.33 |
| Cerebral Palsy | 0.3 | 0.3 | 0 |
| Chronic Fatigue Syndrome | 0.3 | 0.4 | -0.33 |
| Chronic Kidney Disease | 0.7 | 0.7 | |
| Chronic Lyme | 0.3 | -0.3 | |
| Coagulation / Micro clot triggering bacteria | 0.4 | 0.4 | |
| Cognitive Function | 0.7 | 0.7 | |
| Colorectal Cancer | 0.7 | 0.3 | 1.33 |
| Constipation | 0.3 | 0.3 | |
| Coronary artery disease | 0.3 | -0.3 | |
| COVID-19 | 0.9 | 0.4 | 1.25 |
| Crohn's Disease | 0.8 | 0.7 | 0.14 |
| Cushing's Syndrome (hypercortisolism) | 0.3 | -0.3 | |
| cystic fibrosis | 0.3 | -0.3 | |
| deep vein thrombosis | 0.3 | -0.3 | |
| Depression | 0.9 | 0.7 | 0.29 |
| Endometriosis | 0.7 | 0.7 | |
| Epilepsy | 0.3 | 0.7 | -1.33 |
| erectile dysfunction | 0.4 | 0.4 | |
| Fibromyalgia | 0.6 | 0.3 | 1 |
| Functional constipation / chronic idiopathic constipation | 0.7 | 0.7 | 0 |
| gallstone disease (gsd) | 0.4 | 0.4 | |
| Generalized anxiety disorder | 0.3 | 0.3 | 0 |
| Gout | 0.3 | 0.3 | |
| Graves' disease | 0.7 | 0.3 | 1.33 |
| Halitosis | 0.3 | 0.3 | |
| Hashimoto's thyroiditis | 0.3 | 0.3 | 0 |
| Heart Failure | 0.7 | 0.7 | |
| hemorrhagic stroke | 0.4 | 0.4 | |
| Hidradenitis Suppurativa | 0.3 | 0.3 | |
| hyperglycemia | 0.7 | -0.7 | |
| hypertension (High Blood Pressure | 0.7 | 0.3 | 1.33 |
| Hypoxia | 0.7 | 0.7 | |
| IgA nephropathy (IgAN) | 0.7 | 0 | 0 |
| Inflammatory Bowel Disease | 0.9 | 0.4 | 1.25 |
| Insomnia | 0.3 | 0.3 | 0 |
| Intelligence | 0.3 | 0.3 | |
| Intracranial aneurysms | 0.7 | 0.7 | |
| Irritable Bowel Syndrome | 0.3 | 0.8 | -1.67 |
| ischemic stroke | 0.7 | 0.3 | 1.33 |
| Liver Cirrhosis | 0.7 | 0.3 | 1.33 |
| Long COVID | 0.8 | 0.7 | 0.14 |
| ME/CFS with IBS | 0.3 | -0.3 | |
| ME/CFS without IBS | 0.4 | -0.4 | |
| Metabolic Syndrome | 0.7 | 0.8 | -0.14 |
| Mood Disorders | 0.8 | 0.7 | 0.14 |
| Multiple Sclerosis | 0.4 | 0.8 | -1 |
| neuropathic pain | 0.7 | -0.7 | |
| Neuropathy (all types) | 0.4 | -0.4 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.4 | 0.3 | 0.33 |
| NonCeliac Gluten Sensitivity | 0.3 | 0.3 | 0 |
| Obesity | 0.7 | 0.7 | 0 |
| obsessive-compulsive disorder | 0.8 | 0.3 | 1.67 |
| Osteoarthritis | 0.4 | 0.3 | 0.33 |
| Osteoporosis | 0.3 | 0.3 | 0 |
| Parkinson's Disease | 0.7 | 0.4 | 0.75 |
| Polycystic ovary syndrome | 0.8 | 0.3 | 1.67 |
| Premenstrual dysphoric disorder | 0.4 | -0.4 | |
| primary biliary cholangitis | 0 | 0 | |
| Primary sclerosing cholangitis | 0.7 | 0.5 | 0.4 |
| Psoriasis | 0.8 | -0.8 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.7 | 0.3 | 1.33 |
| Schizophrenia | 0.8 | 0.7 | 0.14 |
| Sjögren syndrome | 0.4 | 0.8 | -1 |
| Sleep Apnea | 0.3 | -0.3 | |
| Slow gastric motility / Gastroparesis | 0.3 | 0.3 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.3 | 0.3 | |
| Stress / posttraumatic stress disorder | 0.7 | 0.7 | 0 |
| Systemic Lupus Erythematosus | 0.7 | 0.7 | |
| Tourette syndrome | 0.3 | -0.3 | |
| Type 1 Diabetes | 0.3 | 0.3 | 0 |
| Type 2 Diabetes | 0.7 | 0.8 | -0.14 |
| Ulcerative colitis | 0.8 | 0.8 | 0 |
| Unhealthy Ageing | 0.3 | 0.4 | -0.33 |
| Vitiligo | 0.7 | 0.4 | 0.75 |
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