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🍽️ dorzolamide hydrochloride,(prescription)

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  1. Reduction of Intraocular Pressure (IOP): Dorzolamide is a carbonic anhydrase inhibitor that works by decreasing the production of aqueous humor in the eye, thereby lowering intraocular pressure. It is typically used as an adjunctive therapy when monotherapy with beta-blockers or prostaglandin analogs is insufficient to control IOP.

  2. Treatment of Open-Angle Glaucoma: Open-angle glaucoma is a chronic eye condition characterized by increased fluid pressure within the eye, which can damage the optic nerve and lead to vision loss. Dorzolamide, either alone or in combination with other anti-glaucoma medications, is used to manage this condition and prevent further optic nerve damage.

  3. Management of Ocular Hypertension: Ocular hypertension refers to elevated intraocular pressure without signs of optic nerve damage or visual field loss characteristic of glaucoma. Dorzolamide can be prescribed to lower IOP in individuals with ocular hypertension to reduce the risk of developing glaucoma.

  4. Adjunctive Therapy: Dorzolamide is often prescribed in combination with other intraocular pressure-lowering medications, such as beta-blockers (e.g., timolol) or prostaglandin analogs (e.g., latanoprost), to achieve optimal IOP control. Combination therapy may offer additive or synergistic effects in reducing IOP.

  5. Improved Ocular Blood Flow: Some studies suggest that dorzolamide may have vasodilatory effects on ocular blood vessels, potentially improving ocular perfusion and blood flow to the retina and optic nerve head. This may contribute to its neuroprotective properties in glaucoma management.

  6. Decreased Risk of Visual Field Loss: By effectively lowering intraocular pressure, dorzolamide helps reduce the risk of progressive visual field loss and deterioration of visual function associated with glaucoma. Early initiation and consistent use of dorzolamide therapy may help preserve vision in affected individuals.

  7. Enhanced Outflow Facility: Dorzolamide may enhance aqueous outflow through the trabecular meshwork, facilitating the drainage of intraocular fluid from the eye. This mechanism of action contributes to its ability to reduce intraocular pressure and improve ocular hemodynamics.

  8. Adjunctive Therapy in Pediatric Glaucoma: Dorzolamide can be used as adjunctive therapy in children and adolescents with pediatric glaucoma to lower intraocular pressure and prevent optic nerve damage. It is often administered in combination with other topical anti-glaucoma medications.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of dorzolamide hydrochloride,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium longum Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by dorzolamide hydrochloride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Lacticaseibacillus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Roseburia genus Decreases
0 1 Bilophila genus Decreases
0 1 Streptococcus genus Decreases
0 1 Coprococcus genus Decreases
0 1 Agathobacter genus Decreases
0 1 Bacteroides genus Decreases
0 1 Escherichia genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Shigella genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Wansuia genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Wujia genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Massilistercora genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Simiaoa genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Eubacterium genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Dorea genus Decreases
0 1 Qiania genus Decreases
0 1 Segatella genus Decreases
0 1 Christensenella genus Decreases
0 1 Treponema genus Decreases
0 1 Lachnospira genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Faecalibacterium genus Decreases
0 1 Faecalibacillus genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Adlercreutzia genus Decreases
0 1 Chordicoccus genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Vescimonas genus Decreases
0 1 Collinsella genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Coprococcus comes species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Escherichia coli species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Phocaeicola vulgatus species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Coprococcus catus species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Dorea longicatena species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Blautia argi species Decreases
1 0 Segatella copri species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Dorea formicigenerans species Decreases
0 1 Blautia obeum species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Roseburia hominis species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Shigella boydii species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Blautia liquoris species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Streptococcus suis species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Christensenella minuta species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Treponema peruense species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Lachnospira eligens species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Streptococcus australis species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Parvimonas micra species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Shigella sonnei species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Treponema denticola species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Actinomyces oris species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Blautia hansenii species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Bacteroides faecium species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Blautia parvula species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Collinsella aerofaciens species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Blautia producta species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Thomasclavelia ramosa species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Alistipes communis species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Bacteroides caecimuris species Decreases
0 1 Enterocloster bolteae species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Romboutsia sp. 13368 species Decreases
0 1 Alistipes indistinctus species Decreases
0 1 Streptococcus sp. A12 species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Streptococcus cristatus species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Bifidobacterium longum species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases

Impact of dorzolamide hydrochloride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.5 0.5
Acne 0 0
ADHD 1.7 1.1 0.55
Age-Related Macular Degeneration and Glaucoma 0.8 0 0
Allergic Rhinitis (Hay Fever) 2 2 0
Allergies 3.3 1.4 1.36
Allergy to milk products 1.8 0.9 1
Alopecia (Hair Loss) 0.4 0.2 1
Alzheimer's disease 4.3 6.1 -0.42
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.1 0.9 1.33
Ankylosing spondylitis 2.6 1.5 0.73
Anorexia Nervosa 0.6 2.7 -3.5
Antiphospholipid syndrome (APS) 1.5 0.4 2.75
Asthma 3.5 1.6 1.19
Atherosclerosis 2.4 1.3 0.85
Atrial fibrillation 2.5 2.5 0
Autism 5.3 6.3 -0.19
Autoimmune Disease 0.9 0.6 0.5
Barrett esophagus cancer 0.2 0.4 -1
benign prostatic hyperplasia 0.5 0.4 0.25
Biofilm 2.7 2.7
Bipolar Disorder 1.7 1 0.7
Brain Trauma 0.7 1.2 -0.71
Breast Cancer 1 1
Cancer (General) 0.2 0.9 -3.5
Carcinoma 3.3 1.4 1.36
Celiac Disease 3 1.4 1.14
Cerebral Palsy 0.8 1 -0.25
Chronic Fatigue Syndrome 3.4 5.1 -0.5
Chronic Kidney Disease 2.3 3 -0.3
Chronic Lyme 0.8 -0.8
Chronic Obstructive Pulmonary Disease (COPD) 3 1.8 0.67
Chronic Urticaria (Hives) 1.2 1.1 0.09
Coagulation / Micro clot triggering bacteria 1.6 1.6 0
Cognitive Function 1.5 1.2 0.25
Colorectal Cancer 6.8 2.2 2.09
Constipation 1.4 0.6 1.33
Coronary artery disease 3 3.2 -0.07
COVID-19 4.3 8.4 -0.95
Crohn's Disease 7.2 4.6 0.57
Cushing's Syndrome (hypercortisolism) 0.7 -0.7
cystic fibrosis 0.8 0.9 -0.13
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 2.5 1.9 0.32
Denture Wearers Oral Shifts 1.6 1.6
Depression 7.3 6.6 0.11
Dermatomyositis 0.4 0 0
Eczema 1.9 1.7 0.12
Endometriosis 2.6 1.6 0.63
Eosinophilic Esophagitis 0.2 0.4 -1
Epilepsy 3.2 0.6 4.33
erectile dysfunction 1.1 0 0
Fibromyalgia 1 1.6 -0.6
Functional constipation / chronic idiopathic constipation 4.5 2.7 0.67
gallstone disease (gsd) 2.6 0.9 1.89
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.8 1.3 0.38
Generalized anxiety disorder 2.9 1.3 1.23
Glioblastoma 0.1 0.5 -4
Gout 1.4 0.5 1.8
Graves' disease 0.5 1.7 -2.4
Gulf War Syndrome 0.8 0.6 0.33
Halitosis 1.6 0.4 3
Hashimoto's thyroiditis 2.4 1.5 0.6
Heart Failure 4.1 2.1 0.95
hemorrhagic stroke 0.5 0.5
Hidradenitis Suppurativa 1.5 1.5
High Histamine/low DAO 1 0.3 2.33
hypercholesterolemia (High Cholesterol) 0.6 0.2 2
hyperglycemia 2 0.5 3
Hyperlipidemia (High Blood Fats) 0.7 0.2 2.5
hypersomnia 0.5 -0.5
hypertension (High Blood Pressure 2.3 3.9 -0.7
Hypothyroidism 0.2 0.8 -3
Hypoxia 0.6 0.6
IgA nephropathy (IgAN) 1.2 1.9 -0.58
Inflammatory Bowel Disease 6.4 7.3 -0.14
Insomnia 2.2 1.9 0.16
Intelligence 1.4 0.8 0.75
Intracranial aneurysms 0.7 0.7 0
Irritable Bowel Syndrome 4.4 3 0.47
ischemic stroke 1.5 1.7 -0.13
Juvenile idiopathic arthritis 0.1 -0.1
Liver Cirrhosis 5.8 3.7 0.57
Long COVID 4.7 4.7 0
Low bone mineral density 1.5 -1.5
Lung Cancer 0.9 0.6 0.5
Lymphoma 0.5 0.5
Mast Cell Issues / mastitis 1.3 0.5 1.6
ME/CFS with IBS 0.6 2.4 -3
ME/CFS without IBS 1.4 1 0.4
membranous nephropathy 0.4 0.4
Menopause 0.7 0.7 0
Metabolic Syndrome 6.7 5.2 0.29
Mood Disorders 6.5 5 0.3
multiple chemical sensitivity [MCS] 1.1 0.1 10
Multiple Sclerosis 3.7 4.2 -0.14
Multiple system atrophy (MSA) 0.8 0.1 7
myasthenia gravis 1 0.7 0.43
neuropathic pain 1.2 -1.2
Neuropathy (all types) 0.5 0.9 -0.8
neuropsychiatric disorders (PANDAS, PANS) 0.9 0.1 8
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.7 3.2 0.16
NonCeliac Gluten Sensitivity 0.4 0.4 0
Obesity 7 6.7 0.04
obsessive-compulsive disorder 3.6 2.8 0.29
Osteoarthritis 2.3 1.4 0.64
Osteoporosis 1.4 1.1 0.27
pancreatic cancer 0.8 0.4 1
Parkinson's Disease 6.1 6.7 -0.1
Polycystic ovary syndrome 4.6 1.8 1.56
Postural orthostatic tachycardia syndrome 0.4 -0.4
Premenstrual dysphoric disorder 0.1 0 0
primary biliary cholangitis 0.7 0.9 -0.29
Primary sclerosing cholangitis 1.7 2.1 -0.24
Psoriasis 2.2 2.3 -0.05
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 5.5 3.3 0.67
Rosacea 0.3 0.6 -1
Schizophrenia 2.9 1.8 0.61
scoliosis 1.3 0.7 0.86
sensorineural hearing loss 0.4 0.4
Sjögren syndrome 1.5 1.3 0.15
Sleep Apnea 1.4 1.2 0.17
Slow gastric motility / Gastroparesis 1.1 0 0
Small Intestinal Bacterial Overgrowth (SIBO) 2.2 0 0
Stress / posttraumatic stress disorder 2 1.5 0.33
Systemic Lupus Erythematosus 3.6 1.2 2
Tic Disorder 1 1 0
Tourette syndrome 0.5 0.3 0.67
Type 1 Diabetes 3.3 2.4 0.38
Type 2 Diabetes 7.4 5.2 0.42
Ulcerative colitis 5 4.4 0.14
Unhealthy Ageing 4.2 1.9 1.21
Vitiligo 1.8 0.8 1.25

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