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Bronchodilation: Doxofylline works by relaxing the smooth muscles of the airways, leading to bronchodilation. This helps in easing the breathing difficulties associated with conditions like asthma and COPD.
Anti-inflammatory effects: It may also possess anti-inflammatory properties, which can help reduce airway inflammation, another hallmark of asthma and COPD exacerbations.
Improved lung function: By dilating the airways and reducing inflammation, doxofylline can improve lung function parameters such as forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR).
Reduced symptoms: Patients taking doxofylline may experience a reduction in symptoms such as wheezing, coughing, chest tightness, and shortness of breath.
Fewer exacerbations: Regular use of doxofylline may help in reducing the frequency and severity of asthma or COPD exacerbations, leading to better disease control and improved quality of life.
Lower risk of side effects: Compared to older methylxanthine medications like theophylline, doxofylline is associated with a lower risk of side effects such as gastrointestinal disturbances, cardiac arrhythmias, and drug interactions.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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