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Hypertension: Nilvadipine is effective in lowering blood pressure by relaxing the blood vessels, thus reducing the resistance to blood flow. By dilating the arteries, it allows blood to flow more easily, resulting in decreased blood pressure levels. Controlling hypertension helps reduce the risk of complications such as stroke, heart attack, and kidney problems.
Angina Pectoris: Nilvadipine may be used to manage symptoms of angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By dilating the coronary arteries, nilvadipine improves blood flow to the heart, relieving angina symptoms and reducing the frequency of angina attacks.
Vasospastic Angina: Nilvadipine may also be prescribed for the treatment of vasospastic angina (Prinzmetal's angina), a type of angina caused by sudden narrowing or spasms in the coronary arteries. By relaxing the smooth muscle cells in the arterial walls, nilvadipine helps prevent or relieve coronary artery spasms, thereby improving blood flow to the heart.
Chronic Stable Angina: In addition to vasospastic angina, nilvadipine may be used to manage chronic stable angina, a type of angina that occurs predictably during physical exertion or stress. By reducing myocardial oxygen demand and improving coronary blood flow, nilvadipine helps alleviate chest pain and improve exercise tolerance in individuals with chronic stable angina.
Raynaud's Phenomenon: Nilvadipine has been investigated for its potential role in the management of Raynaud's phenomenon, a condition characterized by vasospasm of the small arteries in the fingers and toes, leading to episodes of color changes, numbness, and pain in response to cold or stress. By dilating blood vessels, nilvadipine may help improve blood circulation and reduce the frequency and severity of Raynaud's attacks.
Side Effects: Common side effects of nilvadipine may include dizziness, headache, flushing, swelling of the ankles or feet (peripheral edema), and gastrointestinal symptoms such as nausea and constipation. These side effects are usually mild and transient but may require medical attention if persistent or severe.
Precautions: Nilvadipine should be used with caution in individuals with liver dysfunction, as it is primarily metabolized in the liver. Dose adjustments may be necessary in patients with hepatic impairment to avoid excessive drug accumulation. Additionally, nilvadipine should not be used in pregnant women or nursing mothers unless the potential benefits outweigh the risks.
Drug Interactions: Nilvadipine may interact with other medications, including certain antihypertensive drugs, antifungal agents, antibiotics, and grapefruit juice, leading to increased or decreased plasma concentrations of nilvadipine or other drugs. It is important to consult a healthcare professional or pharmacist before starting or stopping any medications while taking nilvadipine.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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