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Staphylococcal Infections: Cloxacillin is primarily used to treat infections caused by Staphylococcus aureus, including skin and soft tissue infections, wound infections, abscesses, cellulitis, and osteomyelitis. It is effective against both methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus (MSSA and MRSA).
Streptococcal Infections: Cloxacillin may also be used to treat infections caused by Streptococcus species, although it is less commonly prescribed for this purpose compared to other antibiotics such as penicillin or amoxicillin.
Other Gram-Positive Infections: In addition to Staphylococcus and Streptococcus infections, cloxacillin may have activity against other gram-positive bacteria such as some species of Enterococcus.
Skin and Soft Tissue Infections: Cloxacillin is particularly effective in treating skin and soft tissue infections caused by Staphylococcus aureus, including impetigo, cellulitis, folliculitis, and infected wounds.
Surgical Prophylaxis: Cloxacillin may be used prophylactically to prevent surgical site infections in procedures where the risk of Staphylococcus aureus infection is high, such as orthopedic surgeries or surgeries involving implants.
Bone and Joint Infections: Cloxacillin is sometimes used in the treatment of bone and joint infections, including osteomyelitis and septic arthritis, especially when caused by Staphylococcus aureus.
Respiratory Tract Infections: While cloxacillin is not commonly used to treat respiratory tract infections, it may be prescribed in cases where the infection is known or suspected to be caused by Staphylococcus aureus.
Infective Endocarditis: Cloxacillin may be part of the antibiotic regimen used to treat infective endocarditis, particularly in cases where Staphylococcus aureus is the causative organism.
Adverse Reactions: Common side effects of cloxacillin include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. Allergic reactions, including skin rashes and anaphylaxis, are possible but relatively rare.
Antibiotic Resistance: As with all antibiotics, the overuse or misuse of cloxacillin can contribute to the development of antibiotic-resistant bacteria. Therefore, it should only be used when indicated and under the guidance of a healthcare professional.
(a-clox, aclox, amclocillin, amclocin, amcopen, ampi-kur, ampi-plus, ampiclox, ampicloxacillin, ampicloxacin, amplus, ampoxin, an mei lin, anaclosil, anclox, ancocillin, anglocin, aniclox, apen, apo-cloxi, apoclox, auropen, auropen inj., baxin, biclox, bioceena, biocillin, bioclox, biviseal plus, boie cloxacillin, bovaclox, bovaclox dry cow, boviclox, bovimast, boviseal plus, broadiclox, caxin, cefolac-xl, clobex, clocsamed, clopen, clox, cloxa t.o., cloxa-coli, cloxaben t.s., cloxacap, cloxacil, cloxacilina andromaco, cloxacilina biosano, cloxacilina ips, cloxacilina mintlab, cloxacilina normon, cloxacilina opko, cloxacilina sodica l.ch., cloxacillin, cloxacillin acs, cloxacillin community pharm, cloxacillin norbrook, cloxacillin remedica, cloxacillin sinphar, cloxacillin sterimax, cloxacillin stragen, cloxacillin-benzathin, cloxacillin-fresenius vials, cloxacillin-ts, cloxacilline panpharma, cloxadry, cloxagel, cloxahold, cloxal, cloxalene, cloxalene max, cloxalin, cloxam, cloxamam, cloxamast, cloxamed ts, cloxamp, cloxampicillin, cloxampicin, cloxamycin, cloxasel-ts, cloxasian, cloxavan, cloxgen, cloxi-z, cloxicap, cloxil, cloxin, cloxin ts-retard, cloxine, cloxiran, cloxisyrup, coliclox, curaclox, cuxavet ts ogris, dariclox, dc, dicillin, diclomam, dry-clox, dryclox, dryclox xtra, drycloxa-kel, drycloxacil, duoclox, ekvacillin, elaclox, encloxil, eraclox, ficlox, forticlox, fortitude eds, galaclox, gaofen, gelstamp, gentamam, hi-clox, interclox dc, isoxacillin, jielite, juraclox l.a., juraclox l.a. dry cow, kaifa, klox, kloxerate, kloxerate dc plus, kloxerate plus dc, kloxitas, lactastop rood, lacti-cillin, lampicin fort, lewinex, lidoxin, loxacin, loxavit forte, mammicine, mammin ts forte, mammitel, masticlox, masticlox plus, masticoli, mastipent, medaclox, meiclox, meixam, monoclox, navaclox, neomastipra lac, nitroclox la, noroclox, noroclox dc, noxylen, opticlox, orbenil, orbenin, orbenin dc, orbenin dry cow, orbenin enduro, orbenin extra dc, orbenin extra dry cow, orbenin eye, orbenin l.a., orbenin la, orbenin retard, orbénine, orbenor, oxaclen, pan-cloxacillin, pannox, penclodar, penclox high potency milking cow, pencloxin, pharex cloxacillin, pharmawealth lab cloxacillin, phil pharmawealth/karnataka cloxacillin sodium, prevaclox, ritemed cloxacillin, rivaclox, roscilox, seroclox, sheptaclox dc, sinaclox, sinclocillin, solaze, staflocil, stapenor retard, staphyclox, syntarpen, tarigermel, teat seal cross vetpharm, teva-cloxacillin, upha cloxacillin, vetoscon, vetriclox, viccillin s, wedeclox)
| Rank | Probiotic | Impact |
|---|---|---|
| species | Pseudomonas sp. cn4902 | Increases |
| species group | Pseudomonas putida group | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| 📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 1 | 0 | Enterobacteriaceae | family | Increases |
| 1 | 0 | Pseudomonadaceae | family | Increases |
| 1 | 0 | Citrobacter | genus | Increases |
| 1 | 0 | Pseudomonas | genus | Increases |
| 1 | 0 | Staphylococcus aureus | species | Decreases |
| 0 | 1 | Staphylococcus | genus | Decreases |
| 0 | 1 | Plesiomonas | genus | Increases |
| 0 | 1 | Yokenella | genus | Increases |
| 0 | 1 | Pseudescherichia | genus | Increases |
| 0 | 1 | Atlantibacter | genus | Increases |
| 0 | 1 | Lelliottia | genus | Increases |
| 0 | 1 | Pseudocitrobacter | genus | Increases |
| 0 | 1 | Trabulsiella | genus | Increases |
| 0 | 1 | Leclercia | genus | Increases |
| 0 | 1 | Candidatus Profftia | genus | Increases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Acne | 0.5 | 0.5 | |
| ADHD | 0.5 | 0.5 | |
| Allergic Rhinitis (Hay Fever) | 1.1 | 1.1 | |
| Allergies | 1.1 | 1.7 | -0.55 |
| Allergy to milk products | 0.6 | 0.6 | |
| Alopecia (Hair Loss) | 0.6 | -0.6 | |
| Alzheimer's disease | 1.2 | -1.2 | |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.6 | 1.2 | -1 |
| Ankylosing spondylitis | 1.7 | 0.6 | 1.83 |
| Anorexia Nervosa | 0.6 | -0.6 |
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