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Lowering Blood Pressure: Candesartan belongs to a class of medications called angiotensin II receptor blockers (ARBs). It works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thus leading to relaxation of blood vessels and lowering of blood pressure.
Hypertension Management: Candesartan is prescribed to treat hypertension either alone or in combination with other antihypertensive medications. By reducing blood pressure, it helps to decrease the risk of heart attacks, strokes, and other cardiovascular complications associated with high blood pressure.
Heart Failure Treatment: In patients with heart failure, candesartan helps to improve symptoms, increase exercise tolerance, and reduce the risk of hospitalization related to heart failure exacerbations. It does this by reducing the strain on the heart and improving its pumping ability.
Kidney Protection: Candesartan may be used in patients with chronic kidney disease, particularly in those with proteinuria (excess protein in the urine), to slow the progression of kidney damage and reduce the risk of end-stage renal disease.
Diabetic Nephropathy: In individuals with type 2 diabetes and kidney disease (diabetic nephropathy), candesartan may be used to delay the progression of kidney damage and reduce the risk of kidney failure.
Protection of Blood Vessels: Candesartan has been shown to have protective effects on blood vessels, which can help prevent complications associated with conditions such as atherosclerosis (hardening and narrowing of the arteries), stroke, and peripheral artery disease.
Prevention of Stroke: Some studies suggest that ARBs like candesartan may help reduce the risk of stroke in certain patient populations, although further research is needed to confirm this effect.
Management of Left Ventricular Dysfunction: Candesartan may be used in patients with left ventricular systolic dysfunction following a heart attack to improve outcomes and reduce the risk of cardiovascular events.
Migraine Prevention: There is some evidence to suggest that candesartan may be effective in preventing migraines in certain individuals, although it is not a primary indication for the medication.
Potential Renoprotective Effects: Candesartan has been investigated for its potential renoprotective effects in various kidney diseases beyond diabetic nephropathy, but its use in these conditions may vary based on individual patient factors.
(andesart, atacand, atacand hct, atacand plus, ayra, ayra plus, blopress, blopress plus, candea, candecard, candecard plus, candegamma, candepress, candepress comp, candesar, candesar-h, candesartan, candesartan + hct genoptim, candesartan + hidroclorotiazida actavis, candesartan actavis, candesartán genfar, candesartan hct actavis, candesartan hct richter, candesartan hct teva, candesartan hct-ratiopharm, candesartan krka, candesartan orion, candesartan ratiopharm, candesartan richter, candesartan sveikuva, candesartan tad, candesartan teva, candesartan torrent, candesartan/hydrochlorothiazide orion, candesartan/hydrochlorotiazid sandoz, canocombi, canocord, cantab plus, cantar, cardax, carzan, carzan hct, cocardax, forus, giran-h, hyposart, kandepres, kandesartan sandoz, kandesartanas hidrochlorotiazidas torrent, tensart, tensart plus, acrosar, acrosar-d, acrux, acrux plus, advant, advantec, albustix, albustix d, aldireca, amias, amican, ao bi xin, apo-candesartan, apo-candesartan/hctz, arb, atacand plus forte, atacand plus mite, atacand protect, atacand zid, atasart, atasart-h, bilaten, bilaten-d, blodpress plus, blopresid, blopress d, blopress forte, blopress forte plus, blox, blox-d, bo li gao, bokaiqing, cancetil, cancetil plus, cancombino, candalkan, candalkan plus, candapres hct, candea hct, candeblo, candeblo plus, candeblock, candecombi, candecor, candecor comp., candemore, candemore plus, candemox, candemox comp., candepol, candepres, candepres hct, candeprex, candeprex h, cande-q, cande-q comp., canderin, canderox, canderox hctz, candesa, candesagen, candesan, candesan plus, candesarcomp, candesarplus al, candesarstad, candesarstad comp, candesartan - 1 a pharma, candésartan / hydrochlorothiazide actavis, candésartan / hydrochlorothiazide biogaran, candésartan / hydrochlorothiazide cristers, candésartan / hydrochlorothiazide eg, candésartan / hydrochlorothiazide krka, candésartan / hydrochlorothiazide mylan, candésartan / hydrochlorothiazide ranbaxy, candésartan / hydrochlorothiazide sandoz, candésartan / hydrochlorothiazide teva sante, candésartan / hydrochlorothiazide zentiva, candésartan / hydrochlorothiazide zydus, candesartan + hidroclorotiazida azevedos, candesartan + hidroclorotiazida bluepharma, candesartan + hidroclorotiazida ciclum, candesartan + hidroclorotiazida farmoz, candesartan + hidroclorotiazida krka, candesartan + hidroclorotiazida mylan, candesartan + hidroclorotiazida pharmakern, candesartan + hidroclorotiazida ratiopharm, candesartan + hidroclorotiazida sandoz, candesartan + hidroclorotiazida tad, candesartan + hidroclorotiazida teva, candesartan + hidroclorotiazida zentiva, candesartan + hydrochlorothiazide liconsa, candesartan + idroclorotiazide actavis, candesartan + idroclorotiazide doc generici, candesartan + idroclorotiazide eg, candesartan + idroclorotiazide mylan pharma, candesartan + idroclorotiazide sandoz, candesartan + idroclorotiazide teva, candesartan + idroclorotiazide zentiva, candesartan +pharma, candesartan 1a pharma, candesartan abz, candesartan abz comp., candésartan actavis, candesartan al, candesartan almus, candesartan alter, candesartan apotex, candesartan arcana, candesartan aspen, candesartan aurobindo, candesartan azevedos, candesartan basics, candésartan biogaran, candesartan bluepharma, candesartan ciclum, candesartan cilexetil actavis, candesartan cilexetil aurobindo, candesartan cilexetil cf, candesartan cilexetil consilient, candesartan cilexetil focus, candesartan cilexetil hctz focus, candesartan cilexetil hctz krka, candesartan cilexetil hydrochlorothiazide liconsa, candesartan cilexetil krka, candesartan cilexetil liconsa, candesartan cilexetil mylan, candesartan cilexetil ratiopharm, candesartan cilexetil sandoz, candesartan cilexetil teva, candesartan cilexetil torrent, candesartan cilexetil zentiva, candesartan cilexetil/hct cf, candesartan cilexetil/hct jubilant, candesartan cilexetil/hct mylan, candesartan cilexetil/hct ratiopharm, candesartan cilexetil/hct teva, candesartan cilexetil/hct zentiva, candesartan cilexetil/hydrochloorthiazide actavis, candesartan cilexetil/hydrochloorthiazide mylan, candesartan cilexetil/hydrochloorthiazide ratiopharm, candesartan cilexetil/hydrochloorthiazide sandoz, candesartan cilexetil/hydrochloorthiazide teva, candesartan cilexetil/hydrochloorthiazide torrent, candesartan cinfa, candesartan combix, candésartan cristers, candesartan doc generici, candesartan eg, candésartan eg, candésartan evolugen, candesartan farmoz, candesartan g.l., candesartan genericon, candesartan genfar, candesartan germed, candesartan hct helvepharm, candesartan hct pfizer, candesartan helvepharm, candesartan hexal, candesartan hexal comp, candesartan kern, candésartan krka, candesartan mabo, candesartan mylan, candésartan mylan, candésartan mylan pharma, candesartan navamedic, candesartan normon, candesartan osir, candesartan pensa, candesartan pharmakern, candesartan plus - 1 a pharma, candesartan plus hct eg, candesartan plus takeda, candesartan qualigen, candesartan ranbaxy, candésartan ranbaxy, candesartan ratio, candesartan sandoz, candésartan sandoz, candesartan sanis health, candesartan spirig hc, candesartan stada, candesartan takeda, candesartan tecnigen, candésartan teva, candesartan teva plus, candesartan tolife, candesartan winthrop, candesartan zentiva, candésartan zentiva, candésartan zydus, candesartan/hct +pharma, candesartan/hct 1a pharma, candesartan/hct actavis, candesartan/hct arcana, candesartan/hct krka, candesartan/hct ratiopharm, candesartan/hct sandoz, candesartan/hct stada, candesartan/hct teva, candesartan/hctz forte stada genericos, candesartan/hctz sanis health, candesartan/hctz stada genericos, candesartan/hidrochlorotiazida actavis, candesartan/hidrochlorotiazida almus, candesartan/hidrochlorotiazida apotex, candesartan/hidrochlorotiazida cinfa, candesartan/hidrochlorotiazida davurgama, candesartan/hidrochlorotiazida kern pharma, candesartan/hidrochlorotiazida mylan, candesartan/hidrochlorotiazida normon, candesartan/hidrochlorotiazida pharmagenus, candesartan/hidrochlorotiazida ratiomed, candesartan/hidrochlorotiazida ratiopharm, candesartan/hidrochlorotiazida sandoz, candesartan/hidrochlorotiazida tecnigen, candesartan/hidrochlorotiazida teva, candesartan/hydrochlorothiazide actavis, candesartan/hydrochlorothiazide aspen, candesartan/hydrochlorothiazide krka, candesartan/hydrochlorothiazide navamedic, candesartan/hydrochlorothiazide stada, candesartan/hydrochlorothiazide teva, candesartan-actavis, candesartan-actavis comp, candesartancilexetil actavis, candesartancilexetil comp.-ct, candesartancilexetil hennig, candesartancilexetil mylan, candesartancilexetil plus hct stada, candesartancilexetil q-pharma, candesartancilexetil/hct mylan, candesartancilexetil/hydrochlorthiazid krka, candesartancilexetil-ct, candesartan-comp. q-pharma, candesartan-hct g.l., candesartan-ratiopharm, candesartan-ratiopharm comp., candestar, candexetil, candexetil comp, candexil plus, candez, candez plus, candisil hct, candor, candor plus, candpress, candpress comp, cansartan, cansartan plus, cansartan-mepha, cansartan-mepha plus, cantab, canzeno, canzeno hct, cardesart, carzap, carzap h, carzap hct, casarlic, casartan, chat, clastinol, clastinol htc, cocandesargen, co-candesartan apotex, co-candesartan mylan, co-candesartan sandoz, co-candesartan spirig hc, co-candesartan teva, cokenzen, coropres h, da mai, dacten, dacten d, desartan, desartan plus, di zhi ya, ecard hd, ecard lh, geocand plus, giran, globacand, hipostyn, hytacand, kairasec, kandepres plus, kandesar, kandrozid, karbicombi, karbis, kenzen, mylacand, mylacand plus, ni li an, omegacand, omegacand hct, parapres, parapres plus, parapres plus forte, pemzek, pemzek plus, pms-candesartan, pms-candesartan/hctz, prescanden, prescanden hct, ranacand, ran-candesartan, ratacand, ratacand plus astrazeneca, repido, repido plus, sandoz candesartan, sandoz candesartan plus, sarcozide, silardaf, silardaf hct, stadacand, stadacand plus, su na, tandesar, teva-candesartan, texacand, texacand hct, tiadyl, tiadyl plus, todesaar, wei er ya, xi jun ning)
Rank | Probiotic | Impact |
---|---|---|
species | Enterococcus faecalis | Reduces |
species | Escherichia coli | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
1 | 0 | Enterococcus faecalis | species | Decreases |
1 | 0 | Staphylococcus aureus | species | Decreases |
1 | 0 | Bilophila wadsworthia | species | Decreases |
1 | 0 | Fusobacterium nucleatum | species | Decreases |
1 | 0 | Streptococcus salivarius | species | Decreases |
1 | 0 | Segatella copri | species | Decreases |
1 | 0 | Escherichia coli | species | Decreases |
1 | 0 | Parabacteroides merdae | species | Decreases |
1 | 0 | Roseburia intestinalis | species | Decreases |
1 | 0 | Clostridium perfringens | species | Decreases |
0 | 1 | Escherichia | genus | Decreases |
0 | 1 | Roseburia | genus | Decreases |
0 | 1 | Parabacteroides | genus | Decreases |
0 | 1 | Bilophila | genus | Decreases |
0 | 1 | Fusobacterium | genus | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.3 | 0.3 | |
Acne | 0.5 | 0.5 | |
ADHD | 2.1 | 2.1 | |
Age-Related Macular Degeneration and Glaucoma | 0.5 | 0.4 | 0.25 |
Allergic Rhinitis (Hay Fever) | 2 | 0.4 | 4 |
Allergies | 2.1 | 1.1 | 0.91 |
Allergy to milk products | 0.3 | 1 | -2.33 |
Alzheimer's disease | 2.1 | 1.9 | 0.11 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.6 | 0.1 | 5 |
Ankylosing spondylitis | 1.6 | 0.3 | 4.33 |
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