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Gastrointestinal Disturbances: Common side effects of imatinib include nausea, vomiting, diarrhea, and abdominal pain. These symptoms are usually mild to moderate and can often be managed with supportive care or dose adjustments.
Fluid Retention: Imatinib may cause fluid retention, leading to peripheral edema (swelling of the hands and feet) or fluid accumulation in the lungs (pulmonary edema). Patients should be monitored for signs of edema, and diuretics may be prescribed if necessary.
Musculoskeletal Symptoms: Some individuals may experience muscle cramps, muscle pain, or joint pain while taking imatinib. These symptoms are usually mild and transient.
Fatigue: Fatigue is a common side effect of imatinib therapy. Patients may experience increased tiredness or weakness, which can affect their daily activities.
Hematologic Effects: Imatinib may cause hematologic abnormalities, including anemia (low red blood cell count), thrombocytopenia (low platelet count), or neutropenia (low white blood cell count). Regular blood tests are required to monitor these parameters.
Hepatotoxicity: Imatinib can cause liver toxicity, manifesting as elevated liver enzymes (transaminases) or, rarely, liver damage. Liver function tests should be performed regularly during treatment.
Cardiac Effects: Imatinib may prolong the QT interval, which can increase the risk of cardiac arrhythmias, particularly in patients with preexisting cardiovascular conditions.
Skin Rash: Some patients may develop a skin rash or pruritus (itching) while taking imatinib. These symptoms are usually mild and resolve with continued treatment or symptomatic management.
Endocrine Effects: Imatinib may interfere with thyroid function, leading to hypothyroidism or thyroiditis in some patients. Thyroid function should be monitored periodically during treatment.
Interstitial Lung Disease: Rarely, imatinib may cause interstitial lung disease (ILD), a serious condition characterized by inflammation and scarring of lung tissue. Patients experiencing respiratory symptoms such as dyspnea (shortness of breath) should seek medical attention promptly.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of imatinib,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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