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🍽️ levodopa,(prescription)

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  1. Parkinson's Disease: Levodopa is the most effective medication for managing the motor symptoms of Parkinson's disease, such as tremor, rigidity, bradykinesia (slowness of movement), and postural instability. It helps to replenish dopamine levels in the brain, which improves motor function and reduces symptoms.

  2. Dopamine-Responsive Dystonia: Levodopa is also used in the treatment of dopamine-responsive dystonia, a neurological disorder characterized by abnormal muscle tone and involuntary movements. It can help improve motor function and reduce dystonic symptoms in affected individuals.

  3. Motor Fluctuations: Long-term use of levodopa in Parkinson's disease can lead to motor fluctuations, including "on-off" phenomena and dyskinesias. "On-off" phenomena refer to sudden and unpredictable changes in motor function, where patients fluctuate between periods of good mobility ("on" state) and poor mobility ("off" state). Dyskinesias are involuntary movements that can occur as a side effect of levodopa treatment.

  4. Wearing-off: Over time, levodopa's effectiveness may decrease, leading to the phenomenon known as "wearing-off." Wearing-off refers to the gradual return of Parkinson's symptoms before the next dose of medication is due. This can necessitate adjustments to the levodopa dosage or the addition of other medications to manage symptoms more effectively.

  5. Non-Motor Symptoms: Levodopa primarily targets the motor symptoms of Parkinson's disease but may also improve certain non-motor symptoms, such as mood disturbances, cognitive impairment, and autonomic dysfunction, to some extent.

  6. Side Effects: Levodopa treatment can cause side effects, including nausea, vomiting, orthostatic hypotension (low blood pressure upon standing), hallucinations, confusion, insomnia, and impulse control disorders. These side effects may vary in severity and can impact the overall health and well-being of individuals taking levodopa.

  7. Long-term Management: Levodopa is typically used in combination with other medications, such as carbidopa (which enhances levodopa's effectiveness and reduces side effects) and dopamine agonists, to optimize symptom control and minimize adverse effects. The management of levodopa therapy often requires close monitoring and periodic adjustments by healthcare professionals to achieve the best outcomes for patients with Parkinson's disease or dopamine-responsive dystonia.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of levodopa,(prescription) On Probiotics

Rank Probiotic Impact
species Clostridium beijerinckii Reduces
species Clostridium butyricum Reduces
species Escherichia coli Reduces

Bacteria Impacted by levodopa,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Clostridiaceae family Decreases
0 1 Escherichia genus Decreases
0 1 Dorea genus Decreases
0 1 Roseburia genus Decreases
1 0 Clostridium genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Agathobacter genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bilophila genus Decreases
0 1 Clostridioides genus Decreases
0 1 Collinsella genus Decreases
0 1 Coprococcus genus Decreases
0 1 Eggerthella genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Veillonella genus Decreases
0 1 Segatella genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Helicobacter genus Increases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 environmental samples no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 unclassified Clostridium no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Bacteroides caccae species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Lacrimispora saccharolytica species Decreases
0 1 [Butyribacterium] methylotrophicum species Decreases
0 1 Clostridium aceticum species Decreases
0 1 Clostridium acetireducens species Decreases
0 1 Clostridium acidisoli species Decreases
0 1 Clostridium aestuarii species Decreases
0 1 Clostridium akagii species Decreases
0 1 Clostridium algidicarnis species Decreases
0 1 Clostridium algifaecis species Decreases
0 1 Clostridium aminobutyricum species Decreases
0 1 Clostridium amylolyticum species Decreases
0 1 Clostridium aurantibutyricum species Decreases
0 1 Clostridium autoethanogenum species Decreases
0 1 Clostridium boliviensis species Decreases
0 1 Clostridium bovifaecis species Decreases
0 1 Clostridium bovipellis species Decreases
0 1 Clostridium bowmanii species Decreases
0 1 Clostridium caliptrosporum species Decreases
0 1 Clostridium carnis species Decreases
0 1 Clostridium cavendishii species Decreases
0 1 Clostridium celatum species Decreases
0 1 Clostridium chartatabidum species Decreases
0 1 Clostridium chromiireducens species Decreases
0 1 Clostridium colicanis species Decreases
0 1 Clostridium collagenovorans species Decreases
0 1 Clostridium combesii species Decreases
0 1 Clostridium culturomicium species Decreases
0 1 Clostridium cuniculi species Decreases
0 1 Clostridium cylindrosporum species Decreases
0 1 Clostridium diolis species Decreases
0 1 Clostridium disporicum species Decreases
0 1 Clostridium drakei species Decreases
0 1 Clostridium facile species Decreases
0 1 Clostridium fallax species Decreases
0 1 Clostridium fessum species Decreases
0 1 Clostridium formicaceticum species Decreases
0 1 Clostridium frigidicarnis species Decreases
0 1 Clostridium frigoris species Decreases
0 1 Clostridium fungisolvens species Decreases
0 1 Clostridium fusiformis species Decreases
0 1 Clostridium ganghwense species Decreases
0 1 Clostridium grantii species Decreases
0 1 Clostridium haemolyticum species Decreases
0 1 Clostridium homopropionicum species Decreases
0 1 Clostridium hveragerdense species Decreases
0 1 Clostridium hydrogeniformans species Decreases
0 1 Clostridium jeddahitimonense species Decreases
0 1 Clostridium kogasense species Decreases
0 1 Clostridium lacusfryxellense species Decreases
0 1 Clostridium lentum species Decreases
0 1 Clostridium liquoris species Decreases
0 1 Clostridium ljungdahlii species Decreases
0 1 Clostridium longisporum species Decreases
0 1 Clostridium lundense species Decreases
0 1 Clostridium magnum species Decreases
0 1 Clostridium malenominatum species Decreases
0 1 Clostridium massiliamazoniense species Decreases
0 1 Clostridium merdae species Decreases
0 1 Clostridium minihomine species Decreases
0 1 Clostridium moniliforme species Decreases
0 1 Clostridium nigeriense species Decreases
0 1 Clostridium nitrophenolicum species Decreases
0 1 Clostridium novyi species Decreases
0 1 Clostridium oceanicum species Decreases
0 1 Clostridium oryzae species Decreases
0 1 Clostridium paraputrificum species Decreases
0 1 Clostridium paridis species Decreases
0 1 Clostridium phoceensis species Decreases
0 1 Clostridium polyendosporum species Decreases
0 1 Clostridium porci species Decreases
0 1 Clostridium putrefaciens species Decreases
0 1 Clostridium quinii species Decreases
0 1 Clostridium rhizosphaerae species Decreases
0 1 Clostridium ruminantium species Decreases
0 1 Clostridium sardiniense species Decreases
0 1 Clostridium sartagoforme species Decreases
0 1 Clostridium saudiense species Decreases
0 1 Clostridium schirmacherense species Decreases
0 1 Clostridium segne species Decreases
0 1 Clostridium senegalense species Decreases
0 1 Clostridium sp. AP-15 species Decreases
0 1 Clostridium sp. TF01-11 species Decreases
0 1 Clostridium subterminale species Decreases
0 1 Clostridium sulfidigenes species Decreases
0 1 Clostridium swellfunianum species Decreases
0 1 Clostridium tagluense species Decreases
0 1 Clostridium tarantellae species Decreases
0 1 Clostridium tepidiprofundi species Decreases
0 1 Clostridium tepidum species Decreases
0 1 Clostridium tertium species Decreases
0 1 Clostridium tetanomorphum species Decreases
0 1 Clostridium thermoamylolyticum species Decreases
0 1 Clostridium thermobutyricum species Decreases
0 1 Clostridium thermopalmarium species Decreases
0 1 Clostridium thiosulfatireducens species Decreases
0 1 Clostridium tunisiense species Decreases
0 1 Clostridium uliginosum species Decreases
0 1 Clostridium vincentii species Decreases
0 1 Clostridium vulturis species Decreases
0 1 Faecalispora jeddahensis species Decreases
0 1 Clostridium perfringens species Decreases
0 1 Clostridium fermenticellae species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Escherichia coli species Decreases
0 1 Clostridium intestinale species Decreases
0 1 Clostridium acetobutylicum species Decreases
1 0 Segatella copri species Decreases
0 1 Clostridium saccharobutylicum species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Clostridium gasigenes species Decreases
0 1 Clostridium cellulovorans species Decreases
0 1 Clostridium taeniosporum species Decreases
0 1 Clostridium argentinense species Decreases
0 1 Clostridium sporogenes species Decreases
0 1 Clostridium isatidis species Decreases
0 1 Clostridium cochlearium species Decreases
0 1 Clostridium saccharoperbutylacetonicum species Decreases
0 1 Clostridium gelidum species Decreases
0 1 Clostridium butyricum species Decreases
0 1 Clostridium chauvoei species Decreases
0 1 Clostridium septicum species Decreases
1 0 Clostridioides difficile species Decreases
0 1 Clostridium baratii species Decreases
1 0 Coprococcus comes species Decreases
0 1 Clostridium beijerinckii species Decreases
0 1 Clostridium botulinum species Decreases
0 1 Clostridium carboxidivorans species Decreases
1 0 Dorea formicigenerans species Decreases
0 1 Clostridium scatologenes species Decreases
0 1 Clostridium felsineum species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Thomasclavelia ramosa species Decreases
0 1 Clostridium tetani species Decreases
0 1 Clostridium kluyveri species Decreases
0 1 Clostridium tyrobutyricum species Decreases
1 0 Roseburia hominis species Decreases
0 1 Clostridium bornimense species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Mediterraneibacter gnavus species Decreases
0 1 Clostridium neonatale species Decreases
0 1 Clostridium manihotivorum species Decreases
1 0 Veillonella parvula species Decreases
0 1 Clostridium thermarum species Decreases
0 1 Clostridium estertheticum species Decreases
0 1 Clostridium pasteurianum species Decreases
1 0 Helicobacter pylori species Increases
0 1 Clostridium sp. ASF502 strain Decreases
0 1 Helicobacter pylori 25 strain Increases
0 1 Helicobacter pylori 26695 strain Increases
0 1 Helicobacter pylori 908 strain Increases
0 1 Helicobacter pylori F32 strain Increases
0 1 Helicobacter pylori Lithuania75 strain Increases
0 1 Helicobacter pylori oki112 strain Increases
0 1 Helicobacter pylori oki828 strain Increases
0 1 Helicobacter pylori SouthAfrica20 strain Increases
0 1 Helicobacter pylori v225d strain Increases

Impact of levodopa,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.3 0.3
Acne 0.9 1 -0.11
ADHD 1.8 0.6 2
Age-Related Macular Degeneration and Glaucoma 1.1 1.1
Allergic Rhinitis (Hay Fever) 2 0.3 5.67
Allergies 3.3 2.7 0.22
Allergy to milk products 1.9 0.9 1.11
Alopecia (Hair Loss) 0.9 0.6 0.5
Alzheimer's disease 4.1 6 -0.46
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2 1.1 0.82
Ankylosing spondylitis 2.9 0.6 3.83
Anorexia Nervosa 0.8 2 -1.5
Antiphospholipid syndrome (APS) 0.2 0.9 -3.5
Asthma 3.2 1.4 1.29
Atherosclerosis 1.1 2.4 -1.18
Atrial fibrillation 2.1 2.3 -0.1
Autism 5.6 4.2 0.33
Autoimmune Disease 0.6 1.6 -1.67
Barrett esophagus cancer 0.3 0.6 -1
benign prostatic hyperplasia 0.6 0.3 1
Biofilm 0.6 0.6
Bipolar Disorder 2.3 1.7 0.35
Brain Trauma 0.3 1.1 -2.67
Breast Cancer 0.5 0.3 0.67
Cancer (General) 0.3 1.3 -3.33
Carcinoma 2.9 1.5 0.93
Celiac Disease 1.1 2.8 -1.55
Cerebral Palsy 1.1 1.1 0
Chronic Fatigue Syndrome 3.3 2.4 0.38
Chronic Kidney Disease 3.5 1.9 0.84
Chronic Lyme 0.1 0.8 -7
Chronic Obstructive Pulmonary Disease (COPD) 0.8 1.1 -0.38
Chronic Urticaria (Hives) 1.6 0.2 7
Coagulation / Micro clot triggering bacteria 0.8 1.4 -0.75
Cognitive Function 2 1 1
Colorectal Cancer 4.2 3.8 0.11
Constipation 1.4 0.6 1.33
Coronary artery disease 1.7 2.1 -0.24
COVID-19 3.5 5.9 -0.69
Crohn's Disease 4.5 2.4 0.88
Cushing's Syndrome (hypercortisolism) 0.3 -0.3
cystic fibrosis 0.8 0.8 0
d-lactic acidosis (one form of brain fog) 0.2 0.2
deep vein thrombosis 2 1.7 0.18
Denture Wearers Oral Shifts 0 0
Depression 5.4 4.6 0.17
Eczema 1.7 1.4 0.21
Endometriosis 2 1.7 0.18
Eosinophilic Esophagitis 0.9 -0.9
Epilepsy 2 0.3 5.67
erectile dysfunction 1.5 0.6 1.5
Fibromyalgia 2 2.2 -0.1
Functional constipation / chronic idiopathic constipation 2.9 3.8 -0.31
gallstone disease (gsd) 2.6 1 1.6
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.8 0.6 0.33
Generalized anxiety disorder 1.7 1.6 0.06
giant cell arteritis 0.3 0.5 -0.67
Gout 2.7 2 0.35
Graves' disease 1.2 3.2 -1.67
Gulf War Syndrome 0.8 0 0
Halitosis 0.6 0.6 0
Hashimoto's thyroiditis 2.4 1.6 0.5
Heart Failure 2.7 1.5 0.8
hemorrhagic stroke 0.6 0.6
Hidradenitis Suppurativa 0.6 0.3 1
High Histamine/low DAO 1.5 0.3 4
hypercholesterolemia (High Cholesterol) 0.7 0.7
hyperglycemia 0.8 0.7 0.14
Hyperlipidemia (High Blood Fats) 0.6 0.7 -0.17
hypersomnia 0.6 -0.6
hypertension (High Blood Pressure 2.5 1.8 0.39
Hypothyroidism 1.2 -1.2
Hypoxia 2.9 0.5 4.8
IgA nephropathy (IgAN) 0.9 2.6 -1.89
Inflammatory Bowel Disease 3.9 4.7 -0.21
Insomnia 1.7 1.7 0
Intelligence 1.3 0.2 5.5
Intracranial aneurysms 0.6 0.6 0
Irritable Bowel Syndrome 4.5 3.8 0.18
ischemic stroke 1.4 2.6 -0.86
Liver Cirrhosis 4.9 3.3 0.48
Long COVID 3.1 3.2 -0.03
Low bone mineral density 0.8 -0.8
Lung Cancer 1.5 0.9 0.67
Lymphoma 0.9 0.9
Mast Cell Issues / mastitis 0.6 1.2 -1
ME/CFS with IBS 0.5 0.5 0
ME/CFS without IBS 1.6 0.9 0.78
Menopause 0.4 0.8 -1
Metabolic Syndrome 5.3 4.2 0.26
Mood Disorders 4.8 4 0.2
multiple chemical sensitivity [MCS] 0.3 0.3
Multiple Sclerosis 3.6 2.6 0.38
Multiple system atrophy (MSA) 0 0.3 0
myasthenia gravis 0.6 1.3 -1.17
neuropathic pain 0.3 1 -2.33
Neuropathy (all types) 0.3 1.9 -5.33
neuropsychiatric disorders (PANDAS, PANS) 0.2 0.2
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4 2.5 0.6
NonCeliac Gluten Sensitivity 0.9 0.3 2
Obesity 5.4 4.5 0.2
obsessive-compulsive disorder 2.1 2.1 0
Osteoarthritis 1.8 0.6 2
Osteoporosis 2.8 1.3 1.15
pancreatic cancer 0.9 0.3 2
Parkinson's Disease 4.3 5.2 -0.21
Polycystic ovary syndrome 3.1 2.2 0.41
Postural orthostatic tachycardia syndrome 0.5 0.3 0.67
Premenstrual dysphoric disorder 0.3 0.3
primary biliary cholangitis 0.9 0.9 0
Primary sclerosing cholangitis 1.1 1.1 0
Psoriasis 1.5 2 -0.33
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.4 3.6 0.22
Rosacea 1 1.6 -0.6
Schizophrenia 3.4 2.2 0.55
scoliosis 0.5 0.6 -0.2
Sjögren syndrome 1.1 1.2 -0.09
Sleep Apnea 1.2 1.7 -0.42
Slow gastric motility / Gastroparesis 1.1 1.1
Small Intestinal Bacterial Overgrowth (SIBO) 1.6 1.6
Stress / posttraumatic stress disorder 2.1 1.9 0.11
Systemic Lupus Erythematosus 2.9 1.1 1.64
Tic Disorder 0.3 1.1 -2.67
Tourette syndrome 0.6 0.3 1
Type 1 Diabetes 3.5 2.2 0.59
Type 2 Diabetes 4.7 3.5 0.34
Ulcerative colitis 2.9 4.1 -0.41
Unhealthy Ageing 2.6 0.9 1.89
Vitiligo 0.6 0.6 0

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