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🍽️ catharanthine,(prescription)

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  1. Anticancer Activity: Catharanthine, along with another compound vinblastine, has been identified as one of the active ingredients in the Madagascar periwinkle plant that exhibits potent anticancer properties. It works by interfering with cell division, ultimately leading to cell death (apoptosis), making it effective against various types of cancer cells.

  2. Chemotherapy: Catharanthine is used in the synthesis of vinblastine and vincristine, both of which are chemotherapy drugs commonly used in the treatment of leukemia, lymphoma, and certain solid tumors. These drugs are part of a class known as vinca alkaloids, which disrupt microtubule formation during cell division, inhibiting cancer cell growth.

  3. Hypotensive Effects: Catharanthine has been reported to have hypotensive (blood pressure-lowering) effects in animal studies. It acts as a calcium channel blocker, which relaxes blood vessels and reduces peripheral resistance, leading to a decrease in blood pressure. However, further research is needed to determine its efficacy and safety in humans.

  4. Antimicrobial Activity: Some studies suggest that catharanthine may possess antimicrobial properties, inhibiting the growth of certain bacteria and fungi. However, the extent of its antimicrobial activity and its potential applications in clinical settings require further investigation.

  5. Anti-inflammatory Effects: Catharanthine has shown some anti-inflammatory activity in experimental studies. It may help reduce inflammation by inhibiting the production of pro-inflammatory mediators such as cytokines and prostaglandins. However, more research is needed to understand its mechanisms of action and potential therapeutic applications in inflammatory conditions.

  6. Neuroprotective Potential: There is emerging evidence suggesting that catharanthine may have neuroprotective properties, which could be beneficial in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. It may exert its neuroprotective effects through antioxidant and anti-inflammatory mechanisms, but further research is required to explore its therapeutic potential in these conditions.

  7. Cardioprotective Effects: Some preclinical studies have indicated that catharanthine may have cardioprotective effects, potentially reducing the risk of cardiovascular diseases such as atherosclerosis and myocardial infarction. Its mechanisms of action may involve antioxidant, anti-inflammatory, and vasodilatory effects, but clinical studies are needed to validate these findings.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of catharanthine,(prescription) On Probiotics

Bacteria Impacted by catharanthine,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

Impact of catharanthine,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

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