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Hemodynamic Support: Dopamine is commonly used as an intravenous medication to support blood pressure and cardiac output in patients with shock, sepsis, or other conditions leading to low blood pressure. It acts primarily by stimulating adrenergic receptors and increasing peripheral vascular resistance, cardiac contractility, and heart rate.
Vasopressor Effects: In addition to its cardiac effects, dopamine can cause vasoconstriction of peripheral blood vessels, which helps increase blood pressure. It is often used in intensive care settings to manage hypotension and improve tissue perfusion in critically ill patients.
Treatment of Hypotension: Dopamine infusion is indicated for the treatment of hypotension, especially in situations where adequate blood pressure cannot be maintained with fluid resuscitation alone. It is administered intravenously and titrated to achieve the desired hemodynamic parameters.
Cardiogenic Shock: Dopamine may be used as a supportive therapy in patients with cardiogenic shock, a condition characterized by inadequate cardiac output due to myocardial dysfunction. By enhancing myocardial contractility and systemic vascular resistance, dopamine helps improve cardiac function and perfusion.
Septic Shock: Dopamine infusion is sometimes utilized in patients with septic shock to stabilize blood pressure and restore tissue perfusion. However, its use in sepsis management has become less common due to concerns about potential adverse effects and lack of clear evidence of improved outcomes.
Acute Heart Failure: Dopamine may be considered in the management of acute heart failure with associated hypotension or low cardiac output. Its positive inotropic effects can help augment myocardial contractility and improve cardiac performance in these patients.
Renal Perfusion: Dopamine infusion has been historically used to increase renal blood flow and urine output in patients with acute kidney injury or oliguria. However, recent studies have questioned its efficacy in improving renal outcomes, and its routine use for renal support is no longer recommended.
Neurotransmitter Function: In the central nervous system, dopamine plays a crucial role in regulating mood, motivation, reward, and motor function. Dysregulation of dopamine signaling is implicated in various psychiatric disorders, including schizophrenia, bipolar disorder, and Parkinson's disease.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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