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🍽️ alprenolol hydrochloride,(prescription)

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  1. Beta-Blocker Action: Alprenolol hydrochloride works by blocking the effects of adrenaline (epinephrine) and other stress hormones on beta-adrenergic receptors in the body. By inhibiting beta-adrenergic receptors, alprenolol reduces the heart rate, decreases cardiac output, and lowers blood pressure.

  2. Treatment of Hypertension: Alprenolol hydrochloride is used in the treatment of hypertension (high blood pressure). By reducing the workload on the heart and decreasing the force of contraction, alprenolol helps lower blood pressure and improve cardiovascular function.

  3. Management of Angina: Alprenolol hydrochloride may also be used in the management of angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By reducing myocardial oxygen demand and improving coronary blood flow, alprenolol can help relieve angina symptoms and prevent angina attacks.

  4. Arrhythmia Management: Alprenolol hydrochloride is sometimes used in the management of certain cardiac arrhythmias, such as atrial fibrillation or supraventricular tachycardia. By slowing the heart rate and reducing the excitability of cardiac muscle cells, alprenolol can help stabilize heart rhythm and prevent arrhythmia recurrence.

  5. Heart Failure: Beta-blockers, including alprenolol hydrochloride, may be used as adjunctive therapy in the management of chronic heart failure with reduced ejection fraction. By blocking the harmful effects of excessive sympathetic stimulation on the heart, beta-blockers can improve cardiac function and reduce morbidity and mortality in patients with heart failure.

  6. Prevention of Migraine: Some beta-blockers, including alprenolol hydrochloride, have been shown to be effective in the prevention of migraine headaches. The exact mechanism of action in migraine prophylaxis is not fully understood but may involve modulation of neuronal excitability and vasodilation in the brain.

  7. Side Effects: Common side effects of alprenolol hydrochloride may include fatigue, dizziness, lightheadedness, bradycardia (slow heart rate), hypotension (low blood pressure), and gastrointestinal symptoms such as nausea or diarrhea. These side effects are usually mild and transient and may improve with continued use or dose adjustments.

  8. Bronchospasm: Alprenolol hydrochloride, like other non-selective beta-blockers, can exacerbate bronchospasm in patients with asthma or chronic obstructive pulmonary disease (COPD). It should be used with caution in patients with respiratory conditions, and selective beta-blockers may be preferred in these populations.

  9. Masking of Hypoglycemia: Beta-blockers, including alprenolol hydrochloride, can mask the symptoms of hypoglycemia (low blood sugar) in patients with diabetes. Patients should be educated about monitoring blood glucose levels regularly and recognizing alternative signs of hypoglycemia, such as palpitations or sweating.

  10. Withdrawal Syndrome: Abrupt discontinuation of beta-blockers, including alprenolol hydrochloride, can lead to rebound hypertension, tachycardia, or angina exacerbation. Patients should be tapered off beta-blocker therapy gradually under medical supervision to minimize the risk of withdrawal symptoms.

  11. Contraindications: Alprenolol hydrochloride is contraindicated in patients with bradycardia, heart block, cardiogenic shock, decompensated heart failure, severe peripheral arterial disease, or hypersensitivity to the drug or its components.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of alprenolol hydrochloride,(prescription) On Probiotics

Rank Probiotic Impact
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Streptococcus thermophilus Reduces

Bacteria Impacted by alprenolol hydrochloride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Escherichia genus Decreases
0 1 Streptococcus genus Decreases
0 1 Shigella genus Decreases
0 1 Bilophila genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Escherichia coli species Decreases
1 0 Streptococcus salivarius species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Streptococcus parasanguinis species Decreases
0 1 Shigella boydii species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Shigella sonnei species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Streptococcus australis species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of alprenolol hydrochloride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.1 0.1
ADHD 0.4 0.4
Allergic Rhinitis (Hay Fever) 0.8 1.2 -0.5
Allergies 1.3 1.3
Allergy to milk products 0.6 0.4 0.5
Alzheimer's disease 0.8 1.2 -0.5
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.7 0.6 0.17
Ankylosing spondylitis 1.6 1.6
Anorexia Nervosa 0.4 0.4 0
Antiphospholipid syndrome (APS) 1 0.1 9
Asthma 1.6 0.4 3
Atherosclerosis 0.6 0.6
Atrial fibrillation 0.4 0.8 -1
Autism 1 1.7 -0.7
Autoimmune Disease 1 1
Barrett esophagus cancer 0.4 -0.4
benign prostatic hyperplasia 0.7 0.7
Biofilm 1.3 1.3
Bipolar Disorder 0.8 0.8
Brain Trauma 0.4 0.4
Breast Cancer 0.6 0.6
Cancer (General) 0.2 -0.2
Carcinoma 0.9 0.9
Celiac Disease 1 0.1 9
Cerebral Palsy 0.4 0.4
Chronic Fatigue Syndrome 1 0.6 0.67
Chronic Kidney Disease 0.7 0.1 6
Chronic Obstructive Pulmonary Disease (COPD) 2 0.4 4
Chronic Urticaria (Hives) 1.4 1.4
Coagulation / Micro clot triggering bacteria 1.6 0.4 3
Cognitive Function 0.4 0.4 0
Colorectal Cancer 2.7 0.6 3.5
Constipation 0.7 0.7
Coronary artery disease 1.6 1.6
COVID-19 2 1 1
Crohn's Disease 2 2
cystic fibrosis 1 1
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 1.3 0.4 2.25
Denture Wearers Oral Shifts 1 1
Depression 2.1 1.2 0.75
Dermatomyositis 0.4 0.4
Eczema 1 1 0
Endometriosis 1.6 0.6 1.67
Eosinophilic Esophagitis 0.4 -0.4
Epilepsy 1.6 1.6
erectile dysfunction 0.7 0.7
Functional constipation / chronic idiopathic constipation 1.6 1.6
gallstone disease (gsd) 1 1
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.4 -0.4
Generalized anxiety disorder 1.6 0.4 3
Glioblastoma 0.4 -0.4
Gout 0.4 0.3 0.33
Graves' disease 0.4 -0.4
Gulf War Syndrome 0.4 0.4
Halitosis 0.4 0.4 0
Hashimoto's thyroiditis 0.1 -0.1
Heart Failure 1.7 1.7
Hidradenitis Suppurativa 0.5 0.5
High Histamine/low DAO 0.6 0.6
hypercholesterolemia (High Cholesterol) 0.6 0.6
hyperglycemia 2 2
Hyperlipidemia (High Blood Fats) 0.1 0.1
hypersomnia 0.1 -0.1
hypertension (High Blood Pressure 1 0.5 1
IgA nephropathy (IgAN) 0.4 0.4
Inflammatory Bowel Disease 2.7 1.3 1.08
Insomnia 1 0.4 1.5
Intelligence 0.7 0.7
Irritable Bowel Syndrome 1.6 0.4 3
ischemic stroke 1 0.7 0.43
Liver Cirrhosis 2.1 1.1 0.91
Long COVID 0.8 0.1 7
Lung Cancer 0.8 0.8
Lymphoma 0.7 0.7
Mast Cell Issues / mastitis 1 1
ME/CFS with IBS 0.4 0.4
ME/CFS without IBS 0.4 0.4
membranous nephropathy 0.4 0.4
Menopause 0.4 0.4
Metabolic Syndrome 1.9 0.5 2.8
Mood Disorders 1.7 1.2 0.42
multiple chemical sensitivity [MCS] 1.1 1.1
Multiple Sclerosis 2 0.4 4
Multiple system atrophy (MSA) 0.2 0.2
myasthenia gravis 1 1
Neuropathy (all types) 0.4 0.4 0
neuropsychiatric disorders (PANDAS, PANS) 1 1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.6 1.6
Obesity 1.7 1.1 0.55
obsessive-compulsive disorder 1.4 0.4 2.5
Osteoarthritis 0.8 0.4 1
Osteoporosis 0.7 0.4 0.75
pancreatic cancer 0.4 0.4 0
Parkinson's Disease 2.4 0.9 1.67
Polycystic ovary syndrome 1 0.5 1
primary biliary cholangitis 0.4 0.4 0
Primary sclerosing cholangitis 0.6 0.6
Psoriasis 1 1
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.1 1.1
Schizophrenia 0.7 0.7
scoliosis 0.6 0.1 5
Sjögren syndrome 1 1
Sleep Apnea 0.3 0.3
Slow gastric motility / Gastroparesis 0.6 0.6
Small Intestinal Bacterial Overgrowth (SIBO) 1 1
Stress / posttraumatic stress disorder 0.9 0.9
Systemic Lupus Erythematosus 1.1 1.1
Tic Disorder 0.4 0.4
Tourette syndrome 0.4 0.4
Type 1 Diabetes 1.1 0.4 1.75
Type 2 Diabetes 1.7 1 0.7
Ulcerative colitis 1.7 0.1 16
Unhealthy Ageing 0.5 0.5
Vitiligo 0.4 0.4

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