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🍽️ norethindrone,(prescription)

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  1. Contraception: Norethindrone is commonly used in combination with estrogen in oral contraceptive pills (birth control pills) to prevent pregnancy. It works by inhibiting ovulation (the release of an egg from the ovary), thickening cervical mucus to impede sperm penetration, and altering the uterine lining to prevent implantation of a fertilized egg. Norethindrone-only pills (progestin-only pills or minipills) are also available and primarily work by thickening cervical mucus and altering the uterine lining.

  2. Menstrual Disorders: Norethindrone-containing contraceptive pills may be prescribed to regulate menstrual cycles and treat menstrual disorders such as irregular or heavy menstrual bleeding (menorrhagia). By stabilizing hormonal fluctuations, norethindrone can help promote regular and lighter menstrual periods. Progestin-only pills may also be used to manage menstrual irregularities.

  3. Hormone Replacement Therapy (HRT): Norethindrone, often in combination with estrogen, is used in hormone replacement therapy for postmenopausal women to alleviate symptoms of menopause, such as hot flashes, vaginal dryness, and mood changes. It can help replace the hormones that the body stops producing after menopause, thereby reducing symptoms and preventing bone loss.

  4. Endometriosis: Norethindrone may be prescribed to treat endometriosis, a condition in which tissue similar to the lining of the uterus grows outside the uterus, causing pain and other symptoms. By suppressing ovulation and thinning the uterine lining, norethindrone can help alleviate symptoms associated with endometriosis, such as pelvic pain and heavy menstrual bleeding.

  5. Polycystic Ovary Syndrome (PCOS): Norethindrone may be used to regulate menstrual cycles and reduce androgen levels in women with polycystic ovary syndrome (PCOS), a hormonal disorder characterized by irregular periods, excess hair growth, and ovarian cysts. By inhibiting ovulation and lowering androgen levels, norethindrone can help improve symptoms of PCOS.

  6. Breast Cancer: In some cases, norethindrone may be used as part of the treatment for advanced breast cancer, particularly in postmenopausal women. It may help slow the growth of hormone receptor-positive breast cancer cells by blocking estrogen production in the body.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of norethindrone,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Parabacteroides distasonis Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by norethindrone,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Lachnospira genus Decreases
0 1 Bilophila genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Escherichia genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Veillonella genus Decreases
0 1 Shigella genus Decreases
0 1 Wujia genus Decreases
0 1 Simiaoa genus Decreases
0 1 Bacteroides genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Enterocloster genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Escherichia coli species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Veillonella parvula species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Bacteroides xylanisolvens species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Roseburia intestinalis species Decreases
0 1 Shigella boydii species Decreases
0 1 Veillonella rodentium species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Blautia liquoris species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Coprococcus catus species Decreases
0 1 Roseburia hominis species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Coprococcus comes species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
1 0 Enterocloster bolteae species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Streptococcus suis species Decreases
0 1 Veillonella dispar species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
1 0 Fusobacterium nucleatum species Decreases
0 1 Shigella sonnei species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Dysosmobacter welbionis species Decreases
0 1 Alistipes indistinctus species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Veillonella nakazawae species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Marvinbryantia formatexigens species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bifidobacterium longum species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases

Impact of norethindrone,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.4 0.4
Acne 0 0
ADHD 0.6 0.1 5
Age-Related Macular Degeneration and Glaucoma 0.1 0.2 -1
Allergic Rhinitis (Hay Fever) 0.5 0.6 -0.2
Allergies 1.6 0.9 0.78
Allergy to milk products 0.8 0.6 0.33
Alopecia (Hair Loss) 0.4 0.1 3
Alzheimer's disease 1.8 2.1 -0.17
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.1 0.7 0.57
Ankylosing spondylitis 1.9 0.8 1.37
Anorexia Nervosa 0.4 0.8 -1
Antiphospholipid syndrome (APS) 0.6 0.4 0.5
Asthma 1.3 0.4 2.25
Atherosclerosis 0.9 0.2 3.5
Atrial fibrillation 1.2 1.1 0.09
Autism 1.2 3.6 -2
Autoimmune Disease 0.4 0 0
Barrett esophagus cancer 0.2 0.2
benign prostatic hyperplasia 0.4 0.1 3
Biofilm 0.7 0.7
Bipolar Disorder 1.4 0.4 2.5
Brain Trauma 0 0.4 0
Breast Cancer 0.6 0.6
Cancer (General) 0.2 0.2 0
Carcinoma 1.3 0.5 1.6
Celiac Disease 0.9 1.5 -0.67
Cerebral Palsy 0.2 0.3 -0.5
Chronic Fatigue Syndrome 1.7 2.2 -0.29
Chronic Kidney Disease 0.9 1.2 -0.33
Chronic Lyme 0.1 -0.1
Chronic Obstructive Pulmonary Disease (COPD) 0.7 0.6 0.17
Chronic Urticaria (Hives) 0.8 0.1 7
Coagulation / Micro clot triggering bacteria 1 0.2 4
Cognitive Function 0.5 0 0
Colorectal Cancer 1.7 0.7 1.43
Constipation 1.1 1.1
Coronary artery disease 1.1 0.3 2.67
COVID-19 1.9 2.2 -0.16
Crohn's Disease 2.8 1.7 0.65
Cushing's Syndrome (hypercortisolism) 0.1 -0.1
cystic fibrosis 0.7 0.1 6
d-lactic acidosis (one form of brain fog) 0.5 0.5
deep vein thrombosis 0.9 0.3 2
Denture Wearers Oral Shifts 0.4 0.4
Depression 3.1 2.6 0.19
Dermatomyositis 0 0
Eczema 0.7 0 0
Endometriosis 1.2 1.2 0
Eosinophilic Esophagitis 0.1 0.2 -1
Epilepsy 1.1 0.6 0.83
erectile dysfunction 0.5 0 0
Fibromyalgia 0.5 0.3 0.67
Functional constipation / chronic idiopathic constipation 2 0.5 3
gallstone disease (gsd) 1.2 0.1 11
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.4 0.5 -0.25
Generalized anxiety disorder 1 0.1 9
Gout 0.5 0.1 4
Graves' disease 0.6 0.6 0
Gulf War Syndrome 0 0
Halitosis 0.4 0.4
Hashimoto's thyroiditis 0.5 1 -1
Heart Failure 2 0.3 5.67
hemorrhagic stroke 0.2 0.2
Hidradenitis Suppurativa 1 0.2 4
High Histamine/low DAO 0.5 0.2 1.5
hypercholesterolemia (High Cholesterol) 0.5 0.5
hyperglycemia 1.1 0.4 1.75
Hyperlipidemia (High Blood Fats) 0.4 0.4
hypersomnia 0.4 -0.4
hypertension (High Blood Pressure 1.6 1.6 0
Hypothyroidism 0 0
Hypoxia 0.3 0.3
IgA nephropathy (IgAN) 0.5 1.3 -1.6
Inflammatory Bowel Disease 2.2 3.3 -0.5
Insomnia 0.2 0.9 -3.5
Intelligence 0.7 0.1 6
Intracranial aneurysms 0.5 0.5
Irritable Bowel Syndrome 1.7 1.3 0.31
ischemic stroke 1.1 0.6 0.83
Liver Cirrhosis 2.2 1.4 0.57
Long COVID 1.5 2.7 -0.8
Low bone mineral density 0.5 -0.5
Lung Cancer 0.8 0.3 1.67
Lymphoma 0.4 0.4
Mast Cell Issues / mastitis 0.5 0.2 1.5
ME/CFS with IBS 0.1 0.5 -4
ME/CFS without IBS 0.7 -0.7
Menopause 0.3 0.3
Metabolic Syndrome 2.5 1.4 0.79
Mood Disorders 3 2 0.5
multiple chemical sensitivity [MCS] 0.2 0.1 1
Multiple Sclerosis 1.3 1.6 -0.23
Multiple system atrophy (MSA) 0.1 0.2 -1
myasthenia gravis 0.4 0.4
neuropathic pain 0.9 -0.9
Neuropathy (all types) 0.5 -0.5
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.8 1 0.8
NonCeliac Gluten Sensitivity 0.1 0.1 0
Obesity 2.6 1.6 0.63
obsessive-compulsive disorder 2.3 0.1 22
Osteoarthritis 0.3 0.5 -0.67
Osteoporosis 0.8 0.1 7
pancreatic cancer 0.1 0.1
Parkinson's Disease 2.1 2.2 -0.05
Polycystic ovary syndrome 2.2 1.2 0.83
Postural orthostatic tachycardia syndrome 0 0
Premenstrual dysphoric disorder 0 0.2 0
primary biliary cholangitis 0.2 0.1 1
Primary sclerosing cholangitis 0.9 1.1 -0.22
Psoriasis 0.8 0.7 0.14
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2.3 0.4 4.75
Rosacea 0.2 0.1 1
Schizophrenia 1.8 1.1 0.64
scoliosis 0.6 1.2 -1
sensorineural hearing loss 0.1 0.1
Sjögren syndrome 1.1 0.4 1.75
Sleep Apnea 0.4 0.1 3
Slow gastric motility / Gastroparesis 0.9 0 0
Small Intestinal Bacterial Overgrowth (SIBO) 0.7 0 0
Stress / posttraumatic stress disorder 0.9 0.4 1.25
Systemic Lupus Erythematosus 1.3 1.2 0.08
Tic Disorder 0.2 0.1 1
Tourette syndrome 0.1 -0.1
Type 1 Diabetes 1.3 0.9 0.44
Type 2 Diabetes 2.2 1.4 0.57
Ulcerative colitis 2 1.4 0.43
Unhealthy Ageing 0.9 0.2 3.5
Vitiligo 0.9 0.3 2

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