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Bladder Control: Oxybutynin chloride works by relaxing the bladder muscles, thereby reducing urinary urgency and frequency and decreasing involuntary contractions of the bladder.
Overactive Bladder (OAB): Oxybutynin chloride is commonly prescribed for individuals with OAB, a condition characterized by a sudden and uncontrollable urge to urinate, often resulting in urinary incontinence.
Urinary Incontinence: Oxybutynin chloride may be used to manage urinary incontinence, including urge incontinence (leakage of urine due to sudden urges) and mixed incontinence (combination of urge and stress incontinence).
Side Effects: Oxybutynin chloride can cause various side effects, including dry mouth, constipation, blurred vision, dizziness, drowsiness, and urinary retention. These side effects may occur due to the anticholinergic properties of the medication, which can affect multiple bodily systems.
Cognitive Issues: Oxybutynin chloride, like other anticholinergic medications, has the potential to cause cognitive issues, particularly in older adults. It may impair memory, attention, and concentration and increase the risk of confusion and delirium, especially in individuals with pre-existing cognitive impairment or dementia.
Heat Intolerance: Oxybutynin chloride can reduce sweating, leading to decreased heat dissipation from the body. This may increase the risk of heat-related adverse events, such as heatstroke, especially during hot weather or physical exertion.
Dosage Forms: Oxybutynin chloride is available in various dosage forms, including immediate-release tablets, extended-release tablets, transdermal patches, and topical gel formulations. The choice of formulation depends on individual patient factors and preferences.
Drug Interactions: Oxybutynin chloride may interact with other medications, such as anticholinergic drugs, certain antibiotics, antifungal agents, and medications metabolized by the cytochrome P450 system. It is essential to review the patient's medication list and consider potential interactions before prescribing oxybutynin.
Contraindications: Oxybutynin chloride is contraindicated in individuals with urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, and hypersensitivity to the medication or its components.
Special Populations: Caution is advised when prescribing oxybutynin chloride to older adults, individuals with cognitive impairment, and those with certain medical conditions, such as liver or kidney impairment, as they may be more susceptible to adverse effects.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Reduces |
| species | Akkermansia muciniphila | Reduces |
| species | Anaerobutyricum hallii | Reduces |
| species | Bacteroides uniformis | Reduces |
| species | Bifidobacterium adolescentis | Reduces |
| species | Bifidobacterium bifidum | Reduces |
| species | Bifidobacterium breve | Reduces |
| species | Bifidobacterium catenulatum | Reduces |
| species | Bifidobacterium longum | Reduces |
| species | Blautia wexlerae | Reduces |
| species | Christensenella minuta | Reduces |
| species | Escherichia coli | Reduces |
| species | Lactococcus cremoris | Reduces |
| species | Parabacteroides distasonis | Reduces |
| species | Veillonella atypica | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| 📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 0 | 1 | Akkermansiaceae | family | Decreases |
| 0 | 1 | Bifidobacterium | genus | Decreases |
| 0 | 1 | Veillonella | genus | Decreases |
| 0 | 1 | Bilophila | genus | Decreases |
| 0 | 1 | Dorea | genus | Decreases |
| 0 | 1 | Collinsella | genus | Decreases |
| 0 | 1 | Odoribacter | genus | Decreases |
| 0 | 1 | Phocaeicola | genus | Decreases |
| 0 | 1 | Lachnospira | genus | Decreases |
| 0 | 1 | Bacteroides | genus | Decreases |
| 0 | 1 | Agathobacter | genus | Decreases |
| 0 | 1 | Blautia | genus | Decreases |
| 0 | 1 | Clostridioides | genus | Decreases |
| 0 | 1 | Ruminococcus | genus | Decreases |
| 0 | 1 | Enterocloster | genus | Decreases |
| 0 | 1 | Parabacteroides | genus | Decreases |
| 0 | 1 | Segatella | genus | Decreases |
| 0 | 1 | Streptococcus | genus | Decreases |
| 0 | 1 | Thomasclavelia | genus | Decreases |
| 0 | 1 | Coprococcus | genus | Decreases |
| 0 | 1 | Clostridium | genus | Decreases |
| 0 | 1 | Parolsenella | genus | Decreases |
| 0 | 1 | Fusobacterium | genus | Decreases |
| 0 | 1 | Escherichia | genus | Decreases |
| 0 | 1 | Eggerthella | genus | Decreases |
| 0 | 1 | Mediterraneibacter | genus | Decreases |
| 0 | 1 | Roseburia | genus | Decreases |
| 1 | 0 | Akkermansia | genus | Decreases |
| 0 | 1 | Lacrimispora | genus | Decreases |
| 0 | 1 | Clostridium perfringens A | no rank | Decreases |
| 0 | 1 | Clostridium perfringens B | no rank | Decreases |
| 0 | 1 | Clostridium perfringens C | no rank | Decreases |
| 0 | 1 | Clostridium perfringens CPE | no rank | Decreases |
| 0 | 1 | Clostridium perfringens D | no rank | Decreases |
| 0 | 1 | Clostridium perfringens E | no rank | Decreases |
| 0 | 1 | Escherichia coli O1:K1:H7 | no rank | Decreases |
| 0 | 1 | Escherichia coli O139:H1 | no rank | Decreases |
| 0 | 1 | Escherichia coli O141:H4 | no rank | Decreases |
| 0 | 1 | Escherichia coli O145:H34 | no rank | Decreases |
| 0 | 1 | Escherichia coli O15:H12 | no rank | Decreases |
| 0 | 1 | Escherichia coli O155:H21 | no rank | Decreases |
| 0 | 1 | Escherichia coli O158:H23 | no rank | Decreases |
| 0 | 1 | Escherichia coli O16:H48 | no rank | Decreases |
| 0 | 1 | Escherichia coli O170:H18 | no rank | Decreases |
| 0 | 1 | Escherichia coli O18ac:H14 | no rank | Decreases |
| 0 | 1 | Escherichia coli O19:H7 | no rank | Decreases |
| 0 | 1 | Escherichia coli O2:K1:H4 | no rank | Decreases |
| 0 | 1 | Escherichia coli O2:K1:H5 | no rank | Decreases |
| 0 | 1 | Escherichia coli O2:K1:H7 | no rank | Decreases |
| 0 | 1 | Escherichia coli O20:H12 | no rank | Decreases |
| 0 | 1 | Escherichia coli O25:H16 | no rank | Decreases |
| 0 | 1 | Escherichia coli O55:H7 | no rank | Decreases |
| 0 | 1 | Escherichia coli O68:H12 | no rank | Decreases |
| 0 | 1 | Escherichia coli O7:H15 | no rank | Decreases |
| 0 | 1 | Escherichia coli O78:H51 | no rank | Decreases |
| 0 | 1 | Escherichia coli O80:H26 | no rank | Decreases |
| 0 | 1 | Escherichia coli O84:H7 | no rank | Decreases |
| 0 | 1 | Escherichia coli O85:H1 | no rank | Decreases |
| 0 | 1 | environmental samples | no rank | Decreases |
| 0 | 1 | unclassified Akkermansia | no rank | Decreases |
| 0 | 1 | Escherichia coli O103 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O111 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O119 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O121 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O145 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O155 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O157 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O177 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O26 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O3 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O43 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O5 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O78 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O86 | serogroup | Decreases |
| 0 | 1 | Escherichia coli O91 | serogroup | Decreases |
| 0 | 1 | Escherichia coli H20 | serotype | Decreases |
| 0 | 1 | Escherichia coli O1:H42 | serotype | Decreases |
| 0 | 1 | Escherichia coli O1:HNT | serotype | Decreases |
| 0 | 1 | Escherichia coli O10:H32 | serotype | Decreases |
| 0 | 1 | Escherichia coli O10:K5(L):H4 | serotype | Decreases |
| 0 | 1 | Escherichia coli O100:H21 | serotype | Decreases |
| 0 | 1 | Escherichia coli O103:H11 | serotype | Decreases |
| 0 | 1 | Escherichia coli O103:H2 | serotype | Decreases |
| 0 | 1 | Escherichia coli O103:H25 | serotype | Decreases |
| 0 | 1 | Escherichia coli O104:H21 | serotype | Decreases |
| 0 | 1 | Escherichia coli O104:H4 | serotype | Decreases |
| 0 | 1 | Escherichia coli O111:H- | serotype | Decreases |
| 0 | 1 | Escherichia coli O111:H11 | serotype | Decreases |
| 0 | 1 | Escherichia coli O111:H8 | serotype | Decreases |
| 0 | 1 | Escherichia coli O111:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O112ab:H8 | serotype | Decreases |
| 0 | 1 | Escherichia coli O112ac:H19 | serotype | Decreases |
| 0 | 1 | Escherichia coli O113:H21 | serotype | Decreases |
| 0 | 1 | Escherichia coli O114:H49 | serotype | Decreases |
| 0 | 1 | Escherichia coli O118:H16 | serotype | Decreases |
| 0 | 1 | Escherichia coli O121:H19 | serotype | Decreases |
| 0 | 1 | Escherichia coli O121:H7 | serotype | Decreases |
| 0 | 1 | Escherichia coli O123:H11 | serotype | Decreases |
| 0 | 1 | Escherichia coli O125ac:K+:H10 | serotype | Decreases |
| 0 | 1 | Escherichia coli O126:H45 | serotype | Decreases |
| 0 | 1 | Escherichia coli O127:H27 | serotype | Decreases |
| 0 | 1 | Escherichia coli O127:H6 | serotype | Decreases |
| 0 | 1 | Escherichia coli O128:H2 | serotype | Decreases |
| 0 | 1 | Escherichia coli O128ac:H12 | serotype | Decreases |
| 0 | 1 | Escherichia coli O139:H28 | serotype | Decreases |
| 0 | 1 | Escherichia coli O145:H25 | serotype | Decreases |
| 0 | 1 | Escherichia coli O145:H28 | serotype | Decreases |
| 0 | 1 | Escherichia coli O145:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O146:H21 | serotype | Decreases |
| 0 | 1 | Escherichia coli O15:H18 | serotype | Decreases |
| 0 | 1 | Escherichia coli O150:H6 | serotype | Decreases |
| 0 | 1 | Escherichia coli O152:H23 | serotype | Decreases |
| 0 | 1 | Escherichia coli O153:H2 | serotype | Decreases |
| 0 | 1 | Escherichia coli O156:H25 | serotype | Decreases |
| 0 | 1 | Escherichia coli O157:H- | serotype | Decreases |
| 0 | 1 | Escherichia coli O157:H43 | serotype | Decreases |
| 0 | 1 | Escherichia coli O157:H7 | serotype | Decreases |
| 0 | 1 | Escherichia coli O157:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O16:H6 | serotype | Decreases |
| 0 | 1 | Escherichia coli O165:H25 | serotype | Decreases |
| 0 | 1 | Escherichia coli O167:H26 | serotype | Decreases |
| 0 | 1 | Escherichia coli O174:H2 | serotype | Decreases |
| 0 | 1 | Escherichia coli O174:H21 | serotype | Decreases |
| 0 | 1 | Escherichia coli O174:H8 | serotype | Decreases |
| 0 | 1 | Escherichia coli O176:H45 | serotype | Decreases |
| 0 | 1 | Escherichia coli O177:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O2:H6 | serotype | Decreases |
| 0 | 1 | Escherichia coli O2:K2:H1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O25:H1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O25:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O26:H1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O26:H11 | serotype | Decreases |
| 0 | 1 | Escherichia coli O28ac:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O29:H4 | serotype | Decreases |
| 0 | 1 | Escherichia coli O32:H37 | serotype | Decreases |
| 0 | 1 | Escherichia coli O39:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O44:H18 | serotype | Decreases |
| 0 | 1 | Escherichia coli O45:H2 | serotype | Decreases |
| 0 | 1 | Escherichia coli O6:H16 | serotype | Decreases |
| 0 | 1 | Escherichia coli O6:H16:CFA/II | serotype | Decreases |
| 0 | 1 | Escherichia coli O6:K2:H1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O69:H11 | serotype | Decreases |
| 0 | 1 | Escherichia coli O7:H4 | serotype | Decreases |
| 0 | 1 | Escherichia coli O7:K1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O78:H12 | serotype | Decreases |
| 0 | 1 | Escherichia coli O78:H4 | serotype | Decreases |
| 0 | 1 | Escherichia coli O79:H7 | serotype | Decreases |
| 0 | 1 | Escherichia coli O8:H8 | serotype | Decreases |
| 0 | 1 | Escherichia coli O81:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O83:H1 | serotype | Decreases |
| 0 | 1 | Escherichia coli O86:H34 | serotype | Decreases |
| 0 | 1 | Escherichia coli O89m:H10 | serotype | Decreases |
| 0 | 1 | Escherichia coli O89m:H9 | serotype | Decreases |
| 0 | 1 | Escherichia coli O9:H10 | serotype | Decreases |
| 0 | 1 | Escherichia coli O91:H14 | serotype | Decreases |
| 0 | 1 | Escherichia coli O91:NM | serotype | Decreases |
| 0 | 1 | Escherichia coli O99:H6 | serotype | Decreases |
| 0 | 1 | Escherichia coli ONT:H33 | serotype | Decreases |
| 1 | 0 | Bacteroides xylanisolvens | species | Decreases |
| 1 | 0 | Odoribacter splanchnicus | species | Decreases |
| 1 | 0 | Phocaeicola vulgatus | species | Decreases |
| 1 | 0 | Bacteroides caccae | species | Decreases |
| 1 | 0 | Lachnospira eligens | species | Decreases |
| 1 | 0 | Bacteroides ovatus | species | Decreases |
| 1 | 0 | Bacteroides uniformis | species | Decreases |
| 1 | 0 | Bifidobacterium adolescentis | species | Decreases |
| 1 | 0 | Bifidobacterium longum | species | Decreases |
| 1 | 0 | Bilophila wadsworthia | species | Decreases |
| 1 | 0 | Collinsella aerofaciens | species | Decreases |
| 1 | 0 | Dorea formicigenerans | species | Decreases |
| 1 | 0 | Veillonella parvula | species | Decreases |
| 1 | 0 | Agathobacter rectalis | species | Decreases |
| 1 | 0 | Blautia obeum | species | Decreases |
| 1 | 0 | Clostridioides difficile | species | Decreases |
| 1 | 0 | Parabacteroides merdae | species | Decreases |
| 1 | 0 | Ruminococcus bromii | species | Decreases |
| 1 | 0 | Bacteroides thetaiotaomicron | species | Decreases |
| 1 | 0 | Enterocloster bolteae | species | Decreases |
| 1 | 0 | Segatella copri | species | Decreases |
| 1 | 0 | Streptococcus parasanguinis | species | Decreases |
| 1 | 0 | Thomasclavelia ramosa | species | Decreases |
| 1 | 0 | Coprococcus comes | species | Decreases |
| 1 | 0 | Parabacteroides distasonis | species | Decreases |
| 1 | 0 | Clostridium perfringens | species | Decreases |
| 0 | 1 | Streptococcus sp. HSISM1 | species | Decreases |
| 0 | 1 | Streptococcus sp. LPB0220 | species | Decreases |
| 0 | 1 | Veillonella rodentium | species | Decreases |
| 1 | 0 | Fusobacterium nucleatum | species | Decreases |
| 1 | 0 | Escherichia coli | species | Decreases |
| 1 | 0 | Eggerthella lenta | species | Decreases |
| 0 | 1 | Veillonella dispar | species | Decreases |
| 0 | 1 | Bacteroides sp. CACC 737 | species | Decreases |
| 1 | 0 | Bacteroides fragilis | species | Decreases |
| 0 | 1 | Bacteroides luhongzhouii | species | Decreases |
| 0 | 1 | Bifidobacterium breve | species | Decreases |
| 0 | 1 | Veillonella sp. S12025-13 | species | Decreases |
| 0 | 1 | Bifidobacterium angulatum | species | Decreases |
| 0 | 1 | Veillonella nakazawae | species | Decreases |
| 1 | 0 | [Ruminococcus] torques | species | Decreases |
| 0 | 1 | Parolsenella catena | species | Decreases |
| 0 | 1 | Bacteroides sp. DH3716P | species | Decreases |
| 1 | 0 | Roseburia intestinalis | species | Decreases |
| 0 | 1 | Bacteroides humanifaecis | species | Decreases |
| 0 | 1 | Veillonella rogosae | species | Decreases |
| 0 | 1 | Bacteroides sp. D2 | species | Decreases |
| 0 | 1 | Segatella bryantii | species | Decreases |
| 0 | 1 | Parolsenella massiliensis | species | Decreases |
| 0 | 1 | Bacteroides sp. A1C1 | species | Decreases |
| 0 | 1 | Coprococcus catus | species | Decreases |
| 0 | 1 | Dorea longicatena | species | Decreases |
| 0 | 1 | Anaerobutyricum hallii | species | Decreases |
| 0 | 1 | Collinsella stercoris | species | Decreases |
| 0 | 1 | Streptococcus lactarius | species | Decreases |
| 0 | 1 | Blautia sp. SC05B48 | species | Decreases |
| 0 | 1 | Alistipes megaguti | species | Decreases |
| 0 | 1 | Bacteroides sp. M10 | species | Decreases |
| 0 | 1 | Bacteroides sp. HF-162 | species | Decreases |
| 0 | 1 | Wansuia hejianensis | species | Decreases |
| 0 | 1 | Alistipes sp. dk3624 | species | Decreases |
| 0 | 1 | Bacteroides faecium | species | Decreases |
| 0 | 1 | Blautia parvula | species | Decreases |
| 0 | 1 | Eubacterium ventriosum | species | Decreases |
| 0 | 1 | Veillonella atypica | species | Decreases |
| 0 | 1 | Komagataeibacter oboediens | species | Decreases |
| 0 | 1 | Fannyhessea vaginae | species | Decreases |
| 0 | 1 | Coprobacter fastidiosus | species | Decreases |
| 0 | 1 | Ligilactobacillus ruminis | species | Decreases |
| 0 | 1 | uncultured Alistipes sp. | species | Decreases |
| 0 | 1 | Adlercreutzia equolifaciens | species | Decreases |
| 0 | 1 | Butyrivibrio crossotus | species | Decreases |
| 0 | 1 | Eubacterium sp. MSJ-33 | species | Decreases |
| 0 | 1 | Faecalibacillus intestinalis | species | Decreases |
| 0 | 1 | Streptococcus salivarius | species | Decreases |
| 0 | 1 | Butyricimonas virosa | species | Decreases |
| 0 | 1 | Actinomyces naeslundii | species | Decreases |
| 0 | 1 | Bifidobacterium catenulatum | species | Decreases |
| 0 | 1 | Leyella stercorea | species | Decreases |
| 0 | 1 | Bacteroides caecimuris | species | Decreases |
| 0 | 1 | Flavonifractor plautii | species | Decreases |
| 0 | 1 | Streptococcus gordonii | species | Decreases |
| 0 | 1 | Roseburia rectibacter | species | Decreases |
| 0 | 1 | Streptococcus sp. FDAARGOS_192 | species | Decreases |
| 0 | 1 | Barnesiella viscericola | species | Decreases |
| 1 | 0 | Akkermansia muciniphila | species | Decreases |
| 0 | 1 | Streptococcus australis | species | Decreases |
| 0 | 1 | Clostridium sp. M62/1 | species | Decreases |
| 0 | 1 | Olsenella sp. oral taxon 807 | species | Decreases |
| 0 | 1 | Subdoligranulum variabile | species | Decreases |
| 0 | 1 | Pseudobutyrivibrio xylanivorans | species | Decreases |
| 0 | 1 | Clostridium sp. SY8519 | species | Decreases |
| 0 | 1 | [Ruminococcus] lactaris | species | Decreases |
| 0 | 1 | Blautia liquoris | species | Decreases |
| 0 | 1 | Wujia chipingensis | species | Decreases |
| 0 | 1 | Intestinibaculum porci | species | Decreases |
| 0 | 1 | Coprobacter secundus | species | Decreases |
| 0 | 1 | Coprococcus eutactus | species | Decreases |
| 0 | 1 | Alistipes finegoldii | species | Decreases |
| 0 | 1 | Streptococcus infantis | species | Decreases |
| 0 | 1 | Anaerostipes hadrus | species | Decreases |
| 0 | 1 | Shigella dysenteriae | species | Decreases |
| 0 | 1 | Eubacterium limosum | species | Decreases |
| 0 | 1 | Bacillus paralicheniformis | species | Decreases |
| 0 | 1 | Actinomyces oris | species | Decreases |
| 0 | 1 | Faecalibacterium duncaniae | species | Decreases |
| 0 | 1 | Faecalitalea cylindroides | species | Decreases |
| 0 | 1 | Alistipes ihumii | species | Decreases |
| 0 | 1 | Novisyntrophococcus fermenticellae | species | Decreases |
| 0 | 1 | Ruminococcus gauvreauii | species | Decreases |
| 0 | 1 | Bifidobacterium bifidum | species | Decreases |
| 0 | 1 | Streptococcus sp. oral taxon 061 | species | Decreases |
| 0 | 1 | Massilistercora timonensis | species | Decreases |
| 0 | 1 | Parafannyhessea umbonata | species | Decreases |
| 0 | 1 | Shigella flexneri | species | Decreases |
| 0 | 1 | Bacteroides nordii | species | Decreases |
| 0 | 1 | Qiania dongpingensis | species | Decreases |
| 0 | 1 | Hungatella hathewayi | species | Decreases |
| 0 | 1 | Escherichia albertii | species | Decreases |
| 0 | 1 | Alistipes shahii | species | Decreases |
| 0 | 1 | Parvimonas micra | species | Decreases |
| 0 | 1 | Mageeibacillus indolicus | species | Decreases |
| 0 | 1 | Catenibacterium mitsuokai | species | Decreases |
| 0 | 1 | Alistipes communis | species | Decreases |
| 0 | 1 | Mogibacterium diversum | species | Decreases |
| 0 | 1 | Alistipes senegalensis | species | Decreases |
| 0 | 1 | Eubacterium callanderi | species | Decreases |
| 0 | 1 | Alistipes dispar | species | Decreases |
| 0 | 1 | Christensenella minuta | species | Decreases |
| 0 | 1 | Roseburia hominis | species | Decreases |
| 0 | 1 | Vescimonas coprocola | species | Decreases |
| 0 | 1 | Lachnoanaerobaculum gingivalis | species | Decreases |
| 0 | 1 | Vescimonas fastidiosa | species | Decreases |
| 0 | 1 | Streptococcus oralis | species | Decreases |
| 0 | 1 | Eubacterium sp. c-25 | species | Decreases |
| 0 | 1 | [Clostridium] hylemonae | species | Decreases |
| 0 | 1 | Actinomyces sp. oral taxon 169 | species | Decreases |
| 0 | 1 | Ruminococcus bicirculans (ex Wegman et al. 2014) | species | Decreases |
| 0 | 1 | Coprococcus sp. ART55/1 | species | Decreases |
| 0 | 1 | Phoenicibacter congonensis | species | Decreases |
| 0 | 1 | Lactococcus cremoris | species | Decreases |
| 0 | 1 | Corynebacterium durum | species | Decreases |
| 0 | 1 | Alistipes onderdonkii | species | Decreases |
| 1 | 0 | Lacrimispora saccharolytica | species | Decreases |
| 0 | 1 | Streptococcus suis | species | Decreases |
| 0 | 1 | Treponema denticola | species | Decreases |
| 0 | 1 | Butyricimonas faecalis | species | Decreases |
| 0 | 1 | Monoglobus pectinilyticus | species | Decreases |
| 0 | 1 | Catenibacterium sp. co_0103 | species | Decreases |
| 0 | 1 | Simiaoa sunii | species | Decreases |
| 0 | 1 | Ruthenibacterium lactatiformans | species | Decreases |
| 0 | 1 | Lachnoclostridium phocaeense | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I4-1-79 | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I2-3-92 | species | Decreases |
| 0 | 1 | Parabacteroides johnsonii | species | Decreases |
| 0 | 1 | Gordonibacter urolithinfaciens | species | Decreases |
| 0 | 1 | Longicatena caecimuris | species | Decreases |
| 0 | 1 | Streptococcus vestibularis | species | Decreases |
| 0 | 1 | Streptococcus mutans | species | Decreases |
| 0 | 1 | Faecalibacterium sp. IP-3-29 | species | Decreases |
| 0 | 1 | [Eubacterium] hominis | species | Decreases |
| 0 | 1 | Blautia wexlerae | species | Decreases |
| 0 | 1 | Bacteroides cellulosilyticus | species | Decreases |
| 0 | 1 | Marvinbryantia formatexigens | species | Decreases |
| 0 | 1 | Faecalibacterium sp. IP-1-18 | species | Decreases |
| 0 | 1 | Faecalibaculum rodentium | species | Decreases |
| 0 | 1 | Amedibacterium intestinale | species | Decreases |
| 0 | 1 | Prevotella intermedia | species | Decreases |
| 0 | 1 | Ruminococcus champanellensis | species | Decreases |
| 0 | 1 | Eubacterium maltosivorans | species | Decreases |
| 0 | 1 | Actinomyces sp. oral taxon 171 | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I3-3-33 | species | Decreases |
| 0 | 1 | Maliibacterium massiliense | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I4-3-84 | species | Decreases |
| 0 | 1 | Enterocloster clostridioformis | species | Decreases |
| 0 | 1 | Faecalibacterium sp. HTF-F | species | Decreases |
| 0 | 1 | Akkermansia glycaniphila | species | Decreases |
| 0 | 1 | Akkermansia massiliensis | species | Decreases |
| 0 | 1 | Candidatus Akkermansia intestinavium | species | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. infantis | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. longum | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. suillum | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. suis | subspecies | Decreases |
| 0 | 1 | Fusobacterium nucleatum subsp. nucleatum | subspecies | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.9 | 0.9 | |
| Acne | 0.4 | -0.4 | |
| ADHD | 4.3 | 0.6 | 6.17 |
| Age-Related Macular Degeneration and Glaucoma | 0.6 | 0.2 | 2 |
| Allergic Rhinitis (Hay Fever) | 2.2 | 2.8 | -0.27 |
| Allergies | 6.1 | 3 | 1.03 |
| Allergy to milk products | 1.7 | 1.2 | 0.42 |
| Alopecia (Hair Loss) | 1.5 | 0.1 | 14 |
| Alzheimer's disease | 5.5 | 6.1 | -0.11 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2.5 | 0.6 | 3.17 |
| Ankylosing spondylitis | 4.2 | 1 | 3.2 |
| Anorexia Nervosa | 1.6 | 2.5 | -0.56 |
| Antiphospholipid syndrome (APS) | 1.2 | 0.4 | 2 |
| Asthma | 4.5 | 2.2 | 1.05 |
| Atherosclerosis | 2.2 | 1.2 | 0.83 |
| Atrial fibrillation | 3.5 | 2.5 | 0.4 |
| Autism | 7.6 | 8.9 | -0.17 |
| Autoimmune Disease | 0.7 | 0.7 | 0 |
| Barrett esophagus cancer | 0.5 | 0.2 | 1.5 |
| benign prostatic hyperplasia | 0.1 | 0.3 | -2 |
| Biofilm | 1.8 | 1.8 | |
| Bipolar Disorder | 1.6 | 1.1 | 0.45 |
| Brain Trauma | 1.1 | 1 | 0.1 |
| Breast Cancer | 0.5 | 0.5 | |
| Cancer (General) | 0.8 | 2.5 | -2.13 |
| Carcinoma | 3.8 | 2.6 | 0.46 |
| Celiac Disease | 3.1 | 3.9 | -0.26 |
| Cerebral Palsy | 1.6 | 0.9 | 0.78 |
| Chronic Fatigue Syndrome | 5.2 | 7.8 | -0.5 |
| Chronic Kidney Disease | 3.4 | 2.5 | 0.36 |
| Chronic Lyme | 0.5 | 0.4 | 0.25 |
| Chronic Obstructive Pulmonary Disease (COPD) | 1.9 | 1.3 | 0.46 |
| Chronic Urticaria (Hives) | 1.2 | 0.8 | 0.5 |
| Coagulation / Micro clot triggering bacteria | 0.8 | 0.9 | -0.13 |
| Cognitive Function | 2.2 | 1.2 | 0.83 |
| Colorectal Cancer | 5.4 | 2.3 | 1.35 |
| Constipation | 1.6 | 0.4 | 3 |
| Coronary artery disease | 1.7 | 2.7 | -0.59 |
| COVID-19 | 10.7 | 13.2 | -0.23 |
| Crohn's Disease | 7.1 | 5.2 | 0.37 |
| Cushing's Syndrome (hypercortisolism) | 0.9 | -0.9 | |
| cystic fibrosis | 0.4 | 1.7 | -3.25 |
| d-lactic acidosis (one form of brain fog) | 0.2 | 0.2 | |
| deep vein thrombosis | 1.1 | 0.9 | 0.22 |
| Denture Wearers Oral Shifts | 1.4 | 1.4 | |
| Depression | 10.2 | 7.8 | 0.31 |
| Dermatomyositis | 0.2 | 0.4 | -1 |
| Eczema | 1 | 1.8 | -0.8 |
| Endometriosis | 2.4 | 1.8 | 0.33 |
| Eosinophilic Esophagitis | 0.1 | 0.6 | -5 |
| Epilepsy | 2.9 | 1.9 | 0.53 |
| erectile dysfunction | 0.7 | 0.4 | 0.75 |
| Fibromyalgia | 3.1 | 2.4 | 0.29 |
| Functional constipation / chronic idiopathic constipation | 5.1 | 3.7 | 0.38 |
| gallstone disease (gsd) | 2.3 | 0.7 | 2.29 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 1.6 | 1.7 | -0.06 |
| Generalized anxiety disorder | 1.7 | 2 | -0.18 |
| giant cell arteritis | 0.2 | -0.2 | |
| Glioblastoma | 0.2 | -0.2 | |
| Gout | 2.2 | 0.5 | 3.4 |
| Graves' disease | 1.9 | 2.8 | -0.47 |
| Gulf War Syndrome | 0.9 | 1.3 | -0.44 |
| Halitosis | 1.3 | 0.2 | 5.5 |
| Hashimoto's thyroiditis | 2.9 | 1.6 | 0.81 |
| Heart Failure | 3.2 | 1.8 | 0.78 |
| hemorrhagic stroke | 0.7 | 0.7 | |
| Hidradenitis Suppurativa | 1.3 | 0.4 | 2.25 |
| High Histamine/low DAO | 0.9 | 0.7 | 0.29 |
| hypercholesterolemia (High Cholesterol) | 0.8 | 0.1 | 7 |
| hyperglycemia | 1.3 | 1.4 | -0.08 |
| Hyperlipidemia (High Blood Fats) | 1.2 | 0.4 | 2 |
| hypersomnia | 1 | -1 | |
| hypertension (High Blood Pressure | 3.8 | 5.3 | -0.39 |
| Hypothyroidism | 0.2 | 1 | -4 |
| Hypoxia | 1.9 | 1.9 | |
| IgA nephropathy (IgAN) | 1.4 | 4.9 | -2.5 |
| Inflammatory Bowel Disease | 6.9 | 9.7 | -0.41 |
| Insomnia | 2.1 | 2.5 | -0.19 |
| Intelligence | 1.8 | 0.5 | 2.6 |
| Intracranial aneurysms | 1.3 | 0.7 | 0.86 |
| Irritable Bowel Syndrome | 6.1 | 5 | 0.22 |
| ischemic stroke | 2.9 | 0.8 | 2.62 |
| Liver Cirrhosis | 5.7 | 3.4 | 0.68 |
| Long COVID | 7.4 | 8.3 | -0.12 |
| Low bone mineral density | 0.9 | -0.9 | |
| Lung Cancer | 1.1 | 1.3 | -0.18 |
| Lymphoma | 0.1 | 0.1 | |
| Mast Cell Issues / mastitis | 0.6 | 0.9 | -0.5 |
| ME/CFS with IBS | 0.9 | 2.8 | -2.11 |
| ME/CFS without IBS | 0.9 | 2.2 | -1.44 |
| membranous nephropathy | 0.2 | 0.2 | |
| Menopause | 2.4 | 0.2 | 11 |
| Metabolic Syndrome | 6.6 | 7.3 | -0.11 |
| Mood Disorders | 10 | 6.9 | 0.45 |
| multiple chemical sensitivity [MCS] | 0.8 | 0.3 | 1.67 |
| Multiple Sclerosis | 6.3 | 5.8 | 0.09 |
| Multiple system atrophy (MSA) | 0.9 | 0.9 | 0 |
| myasthenia gravis | 0.3 | 0.3 | 0 |
| neuropathic pain | 0.1 | 2 | -19 |
| Neuropathy (all types) | 0.7 | 1.1 | -0.57 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.8 | 0.8 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 4.9 | 5 | -0.02 |
| NonCeliac Gluten Sensitivity | 1.6 | 0.7 | 1.29 |
| Obesity | 9 | 6 | 0.5 |
| obsessive-compulsive disorder | 5.8 | 3.2 | 0.81 |
| Osteoarthritis | 2.6 | 1.4 | 0.86 |
| Osteoporosis | 1.5 | 1.5 | 0 |
| pancreatic cancer | 0.8 | 0.2 | 3 |
| Parkinson's Disease | 7.1 | 6.1 | 0.16 |
| Polycystic ovary syndrome | 5.3 | 3 | 0.77 |
| Postural orthostatic tachycardia syndrome | 0.2 | 0.6 | -2 |
| Premenstrual dysphoric disorder | 1 | 0.2 | 4 |
| primary biliary cholangitis | 1 | 1.5 | -0.5 |
| Primary sclerosing cholangitis | 2.7 | 2.4 | 0.13 |
| Psoriasis | 3.5 | 2.4 | 0.46 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 6.9 | 3.9 | 0.77 |
| Rosacea | 1 | 0.3 | 2.33 |
| Schizophrenia | 7.3 | 2.7 | 1.7 |
| scoliosis | 0.6 | 1.3 | -1.17 |
| sensorineural hearing loss | 0.3 | 0.3 | |
| Sjögren syndrome | 2.8 | 3.1 | -0.11 |
| Sleep Apnea | 1.7 | 1 | 0.7 |
| Slow gastric motility / Gastroparesis | 1.2 | 0.4 | 2 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 1.7 | 0.6 | 1.83 |
| Stress / posttraumatic stress disorder | 2 | 2 | 0 |
| Systemic Lupus Erythematosus | 3.1 | 1.8 | 0.72 |
| Tic Disorder | 1.5 | 2 | -0.33 |
| Tourette syndrome | 0.7 | 0.3 | 1.33 |
| Type 1 Diabetes | 4 | 4 | 0 |
| Type 2 Diabetes | 7.7 | 6.3 | 0.22 |
| Ulcerative colitis | 5 | 6.7 | -0.34 |
| Unhealthy Ageing | 4.6 | 2 | 1.3 |
| Vitiligo | 1.9 | 1.4 | 0.36 |
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