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🍽️ pyrilamine maleate,(prescription)

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  1. Antihistamine Effects: Pyrilamine maleate works by blocking the action of histamine, a substance in the body that is involved in allergic reactions. By inhibiting histamine receptors, pyrilamine maleate helps alleviate symptoms such as itching, sneezing, runny nose, watery eyes, and hives.

  2. Allergic Rhinitis: Pyrilamine maleate is commonly used to relieve symptoms of allergic rhinitis, also known as hay fever. It helps reduce nasal congestion, sneezing, itching, and runny nose caused by allergens such as pollen, dust mites, pet dander, and mold.

  3. Allergic Conjunctivitis: Pyrilamine maleate may also be used to alleviate symptoms of allergic conjunctivitis, including redness, itching, and watering of the eyes due to exposure to allergens.

  4. Urticaria (Hives): Pyrilamine maleate can help relieve the itching and swelling associated with acute and chronic urticaria, commonly known as hives. It blocks histamine receptors in the skin, reducing the allergic response and alleviating symptoms.

  5. Pruritus (Itching): Pyrilamine maleate is sometimes used to relieve generalized itching associated with various skin conditions, including eczema, dermatitis, and insect bites.

  6. Motion Sickness: Pyrilamine maleate has mild sedative properties and may be used to prevent motion sickness and alleviate symptoms such as nausea and vomiting during travel.

  7. Side Effects: Common side effects of pyrilamine maleate may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and urinary retention. These side effects are typically mild and transient, but individuals should exercise caution when operating machinery or driving until they know how the medication affects them.

  8. Central Nervous System Effects: Pyrilamine maleate can penetrate the blood-brain barrier, leading to central nervous system (CNS) effects such as sedation and drowsiness. This sedative effect may be enhanced when pyrilamine maleate is used concomitantly with other CNS depressants, such as alcohol or certain medications.

  9. Drug Interactions: Pyrilamine maleate may interact with other medications, including central nervous system depressants, anticholinergic drugs, and certain antidepressants. These interactions can potentiate the sedative effects of pyrilamine maleate and increase the risk of adverse effects.

  10. Special Populations: Pyrilamine maleate should be used with caution in elderly individuals, as they may be more susceptible to its sedative effects. It should also be used cautiously in children, as sedation and CNS effects may be more pronounced in this population.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of pyrilamine maleate,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium catenulatum Reduces
species Christensenella minuta Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Streptococcus thermophilus Reduces

Bacteria Impacted by pyrilamine maleate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
1 0 Akkermansia genus Decreases
0 1 Streptococcus genus Decreases
0 1 Dorea genus Decreases
0 1 Roseburia genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Escherichia genus Decreases
0 1 Bacteroides genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Segatella genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Shigella genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Veillonella genus Decreases
0 1 Clostridium genus Decreases
0 1 Agathobacter genus Decreases
0 1 Odoribacter genus Decreases
0 1 Collinsella genus Decreases
0 1 Lachnospira genus Decreases
0 1 Blautia genus Decreases
0 1 Bilophila genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Roseburia hominis species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Escherichia coli species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Phocaeicola vulgatus species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
1 0 Segatella copri species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Bacteroides uniformis species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Veillonella parvula species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Anaerobutyricum hallii species Decreases
1 0 Bacteroides fragilis species Decreases
0 1 Coprococcus catus species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Dorea longicatena species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Shigella boydii species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Wansuia hejianensis species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Agathobacter rectalis species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Eubacterium ventriosum species Decreases
1 0 Odoribacter splanchnicus species Decreases
0 1 Coprococcus comes species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Blautia liquoris species Decreases
0 1 Qiania dongpingensis species Decreases
1 0 Collinsella aerofaciens species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Christensenella minuta species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
1 0 Mediterraneibacter gnavus species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Segatella bryantii species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Shigella sonnei species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Streptococcus gordonii species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Blautia obeum species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of pyrilamine maleate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2
Acne 0.2 -0.2
ADHD 2 0.3 5.67
Age-Related Macular Degeneration and Glaucoma 0.6 0.6
Allergic Rhinitis (Hay Fever) 1.4 2 -0.43
Allergies 2.8 2.3 0.22
Allergy to milk products 1.4 0.8 0.75
Alopecia (Hair Loss) 0.3 0.3
Alzheimer's disease 3.7 3.7 0
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2 1 1
Ankylosing spondylitis 2.5 0.5 4
Anorexia Nervosa 0.6 1.1 -0.83
Antiphospholipid syndrome (APS) 0.8 0 0
Asthma 2.8 2.4 0.17
Atherosclerosis 1.2 0.7 0.71
Atrial fibrillation 1.3 1.2 0.08
Autism 4.5 4.9 -0.09
Autoimmune Disease 0.8 0.5 0.6
Barrett esophagus cancer 0.2 0.3 -0.5
benign prostatic hyperplasia 0.3 0.2 0.5
Biofilm 1.3 1.3
Bipolar Disorder 0.7 0.3 1.33
Brain Trauma 0.5 0.7 -0.4
Breast Cancer 0.7 0.7
Cancer (General) 0.3 1.3 -3.33
Carcinoma 1.8 0.8 1.25
Celiac Disease 1.7 1.2 0.42
Cerebral Palsy 1.1 0.5 1.2
Chronic Fatigue Syndrome 2.2 2.8 -0.27
Chronic Kidney Disease 2.4 1.7 0.41
Chronic Lyme 0.4 -0.4
Chronic Obstructive Pulmonary Disease (COPD) 1.8 0.8 1.25
Chronic Urticaria (Hives) 1 1.1 -0.1
Coagulation / Micro clot triggering bacteria 1 0.5 1
Cognitive Function 1 0.9 0.11
Colorectal Cancer 4.5 1.6 1.81
Constipation 0.9 0.3 2
Coronary artery disease 1.4 1.1 0.27
COVID-19 5 7 -0.4
Crohn's Disease 4 2.7 0.48
Cushing's Syndrome (hypercortisolism) 0.5 -0.5
cystic fibrosis 0.6 1.2 -1
d-lactic acidosis (one form of brain fog) 0.4 0.4
deep vein thrombosis 1.5 0.7 1.14
Denture Wearers Oral Shifts 1.3 1.3
Depression 5 4 0.25
Dermatomyositis 0.3 0.2 0.5
Eczema 1 1.8 -0.8
Endometriosis 1.7 0.9 0.89
Eosinophilic Esophagitis 0.1 0.3 -2
Epilepsy 2.4 1.4 0.71
erectile dysfunction 0.8 0.2 3
Fibromyalgia 1 1.1 -0.1
Functional constipation / chronic idiopathic constipation 2.4 2.4 0
gallstone disease (gsd) 1.4 0.9 0.56
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1 0.7 0.43
Generalized anxiety disorder 1.8 1 0.8
giant cell arteritis 0.1 -0.1
Glioblastoma 0.3 -0.3
Gout 1.9 0.5 2.8
Graves' disease 0.6 1.3 -1.17
Gulf War Syndrome 0.4 1.4 -2.5
Halitosis 1 0.3 2.33
Hashimoto's thyroiditis 2.4 1.4 0.71
Heart Failure 1.8 1.1 0.64
hemorrhagic stroke 0.4 0.4
Hidradenitis Suppurativa 0.7 0.1 6
High Histamine/low DAO 0.9 0.2 3.5
hypercholesterolemia (High Cholesterol) 0.6 0.6 0
hyperglycemia 1.8 1.4 0.29
Hyperlipidemia (High Blood Fats) 0.6 0.1 5
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 2.9 2.7 0.07
Hypothyroidism 0.3 0.3 0
Hypoxia 1.2 1.2
IgA nephropathy (IgAN) 0.6 2.1 -2.5
Inflammatory Bowel Disease 5.1 4.6 0.11
Insomnia 1.6 1.8 -0.13
Intelligence 1 0.3 2.33
Intracranial aneurysms 0.4 0.1 3
Irritable Bowel Syndrome 5.1 3 0.7
ischemic stroke 1.2 0.8 0.5
Liver Cirrhosis 4 3 0.33
Long COVID 3.5 2.9 0.21
Low bone mineral density 0.4 -0.4
Lung Cancer 1 1.1 -0.1
Lymphoma 0.3 0.3
Mast Cell Issues / mastitis 0.9 0.2 3.5
ME/CFS with IBS 0.3 1.6 -4.33
ME/CFS without IBS 0.6 1.3 -1.17
membranous nephropathy 0.3 0.3
Menopause 1.2 0.5 1.4
Metabolic Syndrome 3.9 4.3 -0.1
Mood Disorders 5.2 3 0.73
multiple chemical sensitivity [MCS] 1.3 0 0
Multiple Sclerosis 3.7 2.4 0.54
Multiple system atrophy (MSA) 1.6 0.3 4.33
myasthenia gravis 0.6 0.3 1
neuropathic pain 1.4 -1.4
Neuropathy (all types) 0.6 0.6 0
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.1 2.5 0.24
NonCeliac Gluten Sensitivity 1.1 0.4 1.75
Obesity 6.4 4.6 0.39
obsessive-compulsive disorder 2.6 2.7 -0.04
Osteoarthritis 1.6 1.1 0.45
Osteoporosis 0.9 1.3 -0.44
pancreatic cancer 0.6 0.3 1
Parkinson's Disease 4.9 3 0.63
Polycystic ovary syndrome 2.2 1.4 0.57
Postural orthostatic tachycardia syndrome 0.1 0.2 -1
Premenstrual dysphoric disorder 0.3 0.3
primary biliary cholangitis 0.6 0.8 -0.33
Primary sclerosing cholangitis 1.1 0.6 0.83
Psoriasis 2.2 1.5 0.47
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.3 1.7 0.94
Rosacea 0.8 0.3 1.67
Schizophrenia 3.2 1.2 1.67
scoliosis 0.5 0.1 4
sensorineural hearing loss 0.2 0.2
Sjögren syndrome 1.3 1.5 -0.15
Sleep Apnea 0.8 0.5 0.6
Slow gastric motility / Gastroparesis 0.7 0.2 2.5
Small Intestinal Bacterial Overgrowth (SIBO) 1.2 1.2
Stress / posttraumatic stress disorder 2 1.3 0.54
Systemic Lupus Erythematosus 1.5 0.7 1.14
Tic Disorder 0.6 1 -0.67
Tourette syndrome 0.8 0.2 3
Type 1 Diabetes 2.5 1.9 0.32
Type 2 Diabetes 4.3 4.1 0.05
Ulcerative colitis 3 3.8 -0.27
Unhealthy Ageing 2.4 1 1.4
Vitiligo 0.9 0.7 0.29

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