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🍽️ carbimazole,(prescription)

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  1. Hyperthyroidism: Carbimazole is the mainstay treatment for hyperthyroidism. It works by inhibiting the production of thyroid hormones in the thyroid gland. By reducing the synthesis of thyroid hormones, carbimazole helps to normalize hormone levels and alleviate symptoms associated with hyperthyroidism, such as rapid heartbeat (palpitations), weight loss, tremors, heat intolerance, and sweating.

  2. Graves' Disease: Carbimazole is commonly prescribed for the treatment of Graves' disease, an autoimmune disorder that causes hyperthyroidism. In Graves' disease, the immune system produces antibodies that stimulate the thyroid gland to produce excessive amounts of thyroid hormones. Carbimazole helps to control thyroid hormone levels and manage symptoms of Graves' disease.

  3. Thyroid Storm: In severe cases of hyperthyroidism, known as thyroid storm or thyrotoxic crisis, where there is a sudden and extreme increase in thyroid hormone levels, carbimazole may be used as part of emergency treatment to rapidly lower hormone levels and stabilize the patient's condition.

  4. Preparation for Surgery or Radioactive Iodine Therapy: Carbimazole may be prescribed before surgery or radioactive iodine therapy for hyperthyroidism to help normalize thyroid hormone levels and reduce the risk of complications during these procedures.

  5. Maintenance Therapy: Carbimazole is often used as a long-term maintenance therapy for individuals with hyperthyroidism, especially those who are not candidates for surgery or radioactive iodine treatment. It helps to keep thyroid hormone levels within the normal range and control symptoms over an extended period.

  6. Dosage Adjustment: The dosage of carbimazole is typically adjusted based on thyroid function tests to maintain thyroid hormone levels within the target range. Patients may require regular monitoring of thyroid function and adjustment of medication dosage as needed.

  7. Side Effects: Common side effects of carbimazole may include nausea, vomiting, abdominal pain, headache, skin rash, itching, and changes in taste sensation. In rare cases, it can cause more serious side effects such as agranulocytosis (a severe decrease in white blood cell count), which requires immediate medical attention.

  8. Monitoring: Patients taking carbimazole may require regular monitoring of blood cell counts, liver function tests, and thyroid function tests to assess treatment response and detect any potential adverse effects early.

  9. Pregnancy and Breastfeeding: Carbimazole is generally not recommended during pregnancy, especially during the first trimester, due to the potential risk of birth defects. However, in some cases where hyperthyroidism poses a significant risk to the mother and fetus, carbimazole may be used under close medical supervision. It may also pass into breast milk, so its use during breastfeeding should be discussed with a healthcare provider.

  10. Drug Interactions: Carbimazole may interact with other medications, such as blood thinners (anticoagulants) and certain heart medications. Patients should inform their healthcare provider about all medications they are taking to avoid potential interactions.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of carbimazole,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by carbimazole,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Escherichia genus Decreases
0 1 Dorea genus Decreases
0 1 Roseburia genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Bilophila genus Decreases
0 1 Clostridioides genus Decreases
0 1 Collinsella genus Decreases
0 1 Coprococcus genus Decreases
0 1 Eggerthella genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Lachnospira genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Odoribacter genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Streptococcus genus Decreases
0 1 Veillonella genus Decreases
0 1 Clostridium genus Decreases
0 1 Segatella genus Decreases
1 0 Akkermansia genus Decreases
0 1 Enterocloster genus Decreases
0 1 Blautia genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 environmental samples no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Veillonella parvula species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Escherichia coli species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Blautia obeum species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Roseburia hominis species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Segatella copri species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Clostridioides difficile species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Coprococcus comes species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases

Impact of carbimazole,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.4 0.4
Acne 0.6 0.4 0.5
ADHD 2.9 0.6 3.83
Age-Related Macular Degeneration and Glaucoma 1.1 1.1
Allergic Rhinitis (Hay Fever) 2.4 2.5 -0.04
Allergies 4.8 2.6 0.85
Allergy to milk products 1.9 1.2 0.58
Alopecia (Hair Loss) 1 1
Alzheimer's disease 4.3 4.6 -0.07
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.9 0.8 2.62
Ankylosing spondylitis 3.8 0.9 3.22
Anorexia Nervosa 0.9 2.2 -1.44
Antiphospholipid syndrome (APS) 0.9 0.3 2
Asthma 5.7 2.8 1.04
Atherosclerosis 1.7 1.7 0
Atrial fibrillation 2.6 1.6 0.63
Autism 6.9 7.2 -0.04
Autoimmune Disease 1.2 1 0.2
Barrett esophagus cancer 0.6 0.3 1
benign prostatic hyperplasia 0.6 0.3 1
Biofilm 1.4 1.4
Bipolar Disorder 1.7 1.4 0.21
Brain Trauma 0.9 1.1 -0.22
Breast Cancer 0.7 0.7
Cancer (General) 0.9 2.5 -1.78
Carcinoma 3.8 1.9 1
Celiac Disease 1.9 3.1 -0.63
Cerebral Palsy 1.5 1 0.5
Chronic Fatigue Syndrome 3.3 3.9 -0.18
Chronic Kidney Disease 2.7 2 0.35
Chronic Lyme 0.1 0.8 -7
Chronic Obstructive Pulmonary Disease (COPD) 2.5 2 0.25
Chronic Urticaria (Hives) 1.8 0.6 2
Coagulation / Micro clot triggering bacteria 1.3 1 0.3
Cognitive Function 2.7 1.6 0.69
Colorectal Cancer 6.1 2.4 1.54
Constipation 1.3 0.7 0.86
Coronary artery disease 1.6 2 -0.25
COVID-19 7.2 7.3 -0.01
Crohn's Disease 6.1 4.1 0.49
Cushing's Syndrome (hypercortisolism) 0.4 -0.4
cystic fibrosis 1.1 1.8 -0.64
d-lactic acidosis (one form of brain fog) 0.5 0.5
deep vein thrombosis 2.6 1.1 1.36
Denture Wearers Oral Shifts 1.8 1.8
Depression 8.9 7 0.27
Dermatomyositis 0.3 0.3 0
Eczema 1.7 2.1 -0.24
Endometriosis 2.9 2.2 0.32
Eosinophilic Esophagitis 0.3 0.6 -1
Epilepsy 3.5 1.3 1.69
erectile dysfunction 1.6 0.3 4.33
Fibromyalgia 2.2 1 1.2
Functional constipation / chronic idiopathic constipation 3.9 2.3 0.7
gallstone disease (gsd) 2.4 1.3 0.85
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1 1 0
Generalized anxiety disorder 2.8 2.1 0.33
giant cell arteritis 0.2 -0.2
Glioblastoma 0.3 -0.3
Gout 1.4 0.7 1
Graves' disease 1.2 3 -1.5
Gulf War Syndrome 0.9 1.1 -0.22
Halitosis 1.4 0.3 3.67
Hashimoto's thyroiditis 2.8 1.4 1
Heart Failure 2.6 1.2 1.17
hemorrhagic stroke 0.9 0.9
Hidradenitis Suppurativa 1.4 0.3 3.67
High Histamine/low DAO 1.7 0.3 4.67
hypercholesterolemia (High Cholesterol) 1 0.4 1.5
hyperglycemia 2.9 1.3 1.23
Hyperlipidemia (High Blood Fats) 1.1 0.3 2.67
hypersomnia 0.7 -0.7
hypertension (High Blood Pressure 3.4 4.4 -0.29
Hypothyroidism 0.2 1 -4
Hypoxia 3.1 0.4 6.75
IgA nephropathy (IgAN) 1.2 2.4 -1
Inflammatory Bowel Disease 6.5 6.6 -0.02
Insomnia 2.5 2.4 0.04
Intelligence 1.2 0.1 11
Intracranial aneurysms 0.7 0.6 0.17
Irritable Bowel Syndrome 6 3.6 0.67
ischemic stroke 2.5 1.4 0.79
Liver Cirrhosis 7.1 5 0.42
Long COVID 4.4 5.9 -0.34
Low bone mineral density 1.1 -1.1
Lung Cancer 1.1 1.1 0
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 1.1 0.6 0.83
ME/CFS with IBS 0.7 1.5 -1.14
ME/CFS without IBS 1.2 1.6 -0.33
membranous nephropathy 0.3 0.3
Menopause 1.5 0.7 1.14
Metabolic Syndrome 6.4 6.4 0
Mood Disorders 9.2 5.7 0.61
multiple chemical sensitivity [MCS] 1.4 0.1 13
Multiple Sclerosis 6.5 3.4 0.91
Multiple system atrophy (MSA) 1.1 0.4 1.75
myasthenia gravis 0.9 0.7 0.29
neuropathic pain 0.3 2.7 -8
Neuropathy (all types) 0.9 1.7 -0.89
neuropsychiatric disorders (PANDAS, PANS) 1 1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4.7 4.2 0.12
NonCeliac Gluten Sensitivity 1.7 0.6 1.83
Obesity 8.9 7.6 0.17
obsessive-compulsive disorder 3.2 2.7 0.19
Osteoarthritis 1.7 1.1 0.55
Osteoporosis 2.2 1.7 0.29
pancreatic cancer 0.8 0.3 1.67
Parkinson's Disease 7.1 4.5 0.58
Polycystic ovary syndrome 3.6 2.5 0.44
Postural orthostatic tachycardia syndrome 0.2 0.6 -2
Premenstrual dysphoric disorder 0.7 0.7
primary biliary cholangitis 1.2 1.1 0.09
Primary sclerosing cholangitis 2.1 1.1 0.91
Psoriasis 2.8 1.6 0.75
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 6.1 3.6 0.69
Rosacea 0.4 0.7 -0.75
Schizophrenia 6 2.5 1.4
scoliosis 0.7 0.4 0.75
Sjögren syndrome 2.3 1.8 0.28
Sleep Apnea 1.9 1.5 0.27
Slow gastric motility / Gastroparesis 1 0.3 2.33
Small Intestinal Bacterial Overgrowth (SIBO) 2.1 0.5 3.2
Stress / posttraumatic stress disorder 2.8 2.5 0.12
Systemic Lupus Erythematosus 3.4 1.5 1.27
Tic Disorder 0.7 1.3 -0.86
Tourette syndrome 1.1 0.3 2.67
Type 1 Diabetes 3.2 3.4 -0.06
Type 2 Diabetes 6.5 5.5 0.18
Ulcerative colitis 4.6 3.9 0.18
Unhealthy Ageing 3.4 1.6 1.13
Vitiligo 1.3 0.7 0.86

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