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🍽️ budesonide,(prescription)

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  1. Asthma: Budesonide is commonly prescribed as an inhaled corticosteroid (ICS) for the long-term management of asthma. It helps reduce inflammation in the airways, thereby improving breathing and preventing asthma symptoms such as wheezing, coughing, and shortness of breath.

  2. Chronic Obstructive Pulmonary Disease (COPD): Budesonide may be used in combination with a long-acting beta agonist (LABA) to manage symptoms of COPD, including chronic bronchitis and emphysema. The combination therapy helps reduce airway inflammation and improve lung function.

  3. Allergic Rhinitis: Budesonide nasal spray is effective in relieving symptoms of allergic rhinitis (hay fever), such as nasal congestion, sneezing, itching, and runny nose. It reduces inflammation in the nasal passages and provides symptomatic relief.

  4. Nasal Polyps: Budesonide nasal spray is also used to treat nasal polyps, which are noncancerous growths in the nasal passages. It helps reduce the size of nasal polyps and alleviate symptoms such as nasal congestion and difficulty breathing through the nose.

  5. Inflammatory Bowel Disease (IBD): Budesonide is used in the treatment of mild to moderate Crohn's disease and ulcerative colitis, two types of IBD. It helps reduce inflammation in the gastrointestinal tract, leading to symptom relief and disease remission.

  6. Topical Formulations: Budesonide is available in various formulations, including inhalers, nasal sprays, oral capsules, and rectal foams or enemas, depending on the specific condition being treated and the targeted site of action.

  7. Anti-inflammatory Action: Budesonide exerts its therapeutic effects by inhibiting the production of inflammatory mediators and suppressing the immune response. This helps alleviate inflammation, swelling, and irritation associated with inflammatory conditions.

  8. Local and Systemic Side Effects: While budesonide is generally well-tolerated, long-term use or high doses may increase the risk of side effects. Common side effects include sore throat, hoarseness, coughing, dry mouth, oral thrush (candidiasis), and nosebleeds (with nasal spray). Systemic side effects such as adrenal suppression, osteoporosis, and increased susceptibility to infections are more likely with oral formulations.

  9. Monitoring and Adverse Reactions: Patients taking budesonide should be monitored regularly for potential adverse effects, particularly with long-term use. It is important to use the lowest effective dose for the shortest duration necessary to achieve symptom control and to follow healthcare provider recommendations closely.

  10. Contraindications: Budesonide is contraindicated in patients with a known hypersensitivity to corticosteroids or any of the components of the formulation. It should be used with caution in patients with certain medical conditions, such as diabetes, hypertension, glaucoma, and osteoporosis.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of budesonide,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Christensenella minuta Reduces
species Escherichia coli Reduces
species Lactococcus cremoris Reduces
species Parabacteroides distasonis Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by budesonide,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?

📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Blautia genus Decreases
0 1 Collinsella genus Decreases
0 1 Veillonella genus Decreases
0 1 Dorea genus Decreases
0 1 Clostridioides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Odoribacter genus Decreases
0 1 Coprococcus genus Decreases
0 1 Ruminococcus genus Decreases
1 0 Akkermansia genus Decreases
0 1 Bilophila genus Decreases
0 1 Eggerthella genus Decreases
0 1 Parolsenella genus Decreases
0 1 Streptococcus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Enterocloster genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Bacteroides genus Decreases
0 1 Clostridium genus Decreases
0 1 Segatella genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Roseburia genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Escherichia genus Decreases
0 1 Lacrimispora genus Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Blautia obeum species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Veillonella parvula species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Coprococcus comes species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Veillonella rodentium species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Bacteroides xylanisolvens species Decreases
0 1 Veillonella dispar species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Veillonella nakazawae species Decreases
1 0 Roseburia hominis species Decreases
0 1 Parolsenella catena species Decreases
0 1 Veillonella rogosae species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Dorea longicatena species Decreases
0 1 Coprococcus catus species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Blautia sp. SC05B48 species Decreases
1 0 Segatella copri species Decreases
0 1 Veillonella atypica species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Actinomyces naeslundii species Decreases
1 0 Phocaeicola vulgatus species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Coprobacter fastidiosus species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Actinomyces oris species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Parvimonas micra species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Blautia liquoris species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Christensenella minuta species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Bifidobacterium bifidum species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Coprococcus eutactus species Decreases
1 0 [Ruminococcus] torques species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Streptococcus suis species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Alistipes communis species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Roseburia intestinalis species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Escherichia coli species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Bacteroides uniformis species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases

Impact of budesonide,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2
Acne 0.4 -0.4
ADHD 2.9 0.8 2.62
Age-Related Macular Degeneration and Glaucoma 0.6 0.1 5
Allergic Rhinitis (Hay Fever) 2.2 2.5 -0.14
Allergies 5.9 2.8 1.11
Allergy to milk products 1.7 0.8 1.13
Alopecia (Hair Loss) 1.4 1.4
Alzheimer's disease 4.3 3.6 0.19
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.2 0.9 1.44
Ankylosing spondylitis 3 0.8 2.75
Anorexia Nervosa 1.5 1.5 0
Antiphospholipid syndrome (APS) 0.3 0.2 0.5
Asthma 3.5 2.4 0.46
Atherosclerosis 1.4 1.1 0.27
Atrial fibrillation 2.6 1 1.6
Autism 6.9 5.8 0.19
Autoimmune Disease 0.5 0.5 0
Barrett esophagus cancer 0.4 0.1 3
benign prostatic hyperplasia 0 0.1 0
Biofilm 1.6 1.6
Bipolar Disorder 1 1.2 -0.2
Brain Trauma 1.1 0.8 0.38
Breast Cancer 0.1 0.1
Cancer (General) 0.7 1.5 -1.14
Carcinoma 3.1 2.5 0.24
Celiac Disease 1.9 3.5 -0.84
Cerebral Palsy 1.3 0.9 0.44
Chronic Fatigue Syndrome 4.1 6 -0.46
Chronic Kidney Disease 3 1.6 0.88
Chronic Lyme 0.6 0.2 2
Chronic Obstructive Pulmonary Disease (COPD) 1.2 0.9 0.33
Chronic Urticaria (Hives) 0.7 0.7 0
Coagulation / Micro clot triggering bacteria 0.4 1 -1.5
Cognitive Function 1.9 1 0.9
Colorectal Cancer 3.2 1.3 1.46
Constipation 0.5 0.6 -0.2
Coronary artery disease 1.6 2 -0.25
COVID-19 7.8 9.1 -0.17
Crohn's Disease 5 3.8 0.32
Cushing's Syndrome (hypercortisolism) 0.2 -0.2
cystic fibrosis 0.1 1.6 -15
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 0.7 0.6 0.17
Denture Wearers Oral Shifts 0.9 0.9
Depression 6.7 7 -0.04
Dermatomyositis 0.1 0.4 -3
Eczema 1.1 1.3 -0.18
Endometriosis 2 1.4 0.43
Eosinophilic Esophagitis 0.6 -0.6
Epilepsy 2.2 2.2 0
erectile dysfunction 0.2 0.4 -1
Fibromyalgia 2.3 1.3 0.77
Functional constipation / chronic idiopathic constipation 3 2.1 0.43
gallstone disease (gsd) 2.4 0.7 2.43
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.6 1.2 -1
Generalized anxiety disorder 2 1.8 0.11
giant cell arteritis 0.1 -0.1
Glioblastoma 0.1 -0.1
Gout 1 0.6 0.67
Graves' disease 1.7 2.8 -0.65
Gulf War Syndrome 1 1.1 -0.1
Halitosis 0.7 0.1 6
Hashimoto's thyroiditis 2.7 1 1.7
Heart Failure 2.1 1.6 0.31
hemorrhagic stroke 0.5 0.5
Hidradenitis Suppurativa 0.5 0.4 0.25
High Histamine/low DAO 0.4 0.6 -0.5
hypercholesterolemia (High Cholesterol) 0.5 0.5 0
hyperglycemia 0.9 1.8 -1
Hyperlipidemia (High Blood Fats) 1.3 0.5 1.6
hypersomnia 1.2 -1.2
hypertension (High Blood Pressure 3.6 4 -0.11
Hypothyroidism 0.2 1.3 -5.5
Hypoxia 1.5 1.5
IgA nephropathy (IgAN) 0.9 2.6 -1.89
Inflammatory Bowel Disease 5.2 7.5 -0.44
Insomnia 2 2.2 -0.1
Intelligence 0.8 0.1 7
Intracranial aneurysms 1 0.7 0.43
Irritable Bowel Syndrome 4.5 3.6 0.25
ischemic stroke 2.5 0.2 11.5
Liver Cirrhosis 4.7 3.2 0.47
Long COVID 4.7 6.5 -0.38
Low bone mineral density 0.6 -0.6
Lung Cancer 0.3 1.8 -5
Lymphoma 0 0
Mast Cell Issues / mastitis 0.2 0.9 -3.5
ME/CFS with IBS 0.5 2.7 -4.4
ME/CFS without IBS 1.4 1.7 -0.21
membranous nephropathy 0.1 0.1
Menopause 2.1 0.3 6
Metabolic Syndrome 5.6 6.1 -0.09
Mood Disorders 7.4 6.1 0.21
multiple chemical sensitivity [MCS] 0.8 0.5 0.6
Multiple Sclerosis 5.2 3 0.73
Multiple system atrophy (MSA) 1.2 1.1 0.09
myasthenia gravis 0.2 0.2 0
neuropathic pain 0.2 1.5 -6.5
Neuropathy (all types) 1.1 0.8 0.38
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.1 4.6 -0.48
NonCeliac Gluten Sensitivity 2.1 0.5 3.2
Obesity 7.6 5.8 0.31
obsessive-compulsive disorder 3.5 3.2 0.09
Osteoarthritis 1.7 1.2 0.42
Osteoporosis 1.2 1.8 -0.5
pancreatic cancer 0.5 0.1 4
Parkinson's Disease 6.4 3.5 0.83
Polycystic ovary syndrome 4.2 2.8 0.5
Postural orthostatic tachycardia syndrome 0.1 0.6 -5
Premenstrual dysphoric disorder 1.3 0.1 12
primary biliary cholangitis 1 0.7 0.43
Primary sclerosing cholangitis 2 2.6 -0.3
Psoriasis 3.3 1.2 1.75
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 6.4 3 1.13
Rosacea 0.7 0.2 2.5
Schizophrenia 6.1 2.4 1.54
scoliosis 0.5 0.5 0
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 2.4 2.1 0.14
Sleep Apnea 1.8 1.1 0.64
Slow gastric motility / Gastroparesis 0.8 0.4 1
Small Intestinal Bacterial Overgrowth (SIBO) 1.1 0.6 0.83
Stress / posttraumatic stress disorder 1.4 2.3 -0.64
Systemic Lupus Erythematosus 2.9 1.5 0.93
Tic Disorder 0.9 1.6 -0.78
Tourette syndrome 0.8 0.1 7
Type 1 Diabetes 3.1 2.7 0.15
Type 2 Diabetes 5.7 4.6 0.24
Ulcerative colitis 2.7 4.5 -0.67
Unhealthy Ageing 3.3 1.4 1.36
Vitiligo 1.1 1.5 -0.36

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