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🍽️ Pyridoxine {Vitamin B6}

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  1. Metabolism of Amino Acids: Vitamin B6 is involved in the metabolism of amino acids, the building blocks of proteins. It helps convert amino acids into other compounds and facilitates the synthesis of non-essential amino acids. Adequate vitamin B6 levels are essential for maintaining protein metabolism and supporting muscle growth and repair.

  2. Neurotransmitter Synthesis: Vitamin B6 is necessary for the synthesis of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA). These neurotransmitters play critical roles in mood regulation, cognitive function, and stress response. Adequate vitamin B6 levels may help support optimal brain function and mental well-being.

  3. Hemoglobin Formation: Vitamin B6 is involved in the synthesis of hemoglobin, the protein in red blood cells that carries oxygen to tissues throughout the body. Adequate vitamin B6 levels are necessary for proper red blood cell formation and oxygen delivery, and vitamin B6 deficiency can lead to anemia and fatigue.

  4. Immune Function: Vitamin B6 plays a role in supporting immune function by influencing the production and activity of immune cells. It helps regulate the proliferation and differentiation of lymphocytes, which are key components of the immune system. Adequate vitamin B6 levels may help enhance immune response and reduce the risk of infections.

  5. Cardiovascular Health: Some research suggests that vitamin B6 may have benefits for cardiovascular health by helping to lower levels of homocysteine, an amino acid associated with an increased risk of heart disease and stroke. Vitamin B6, along with other B vitamins such as B12 and folate, helps metabolize homocysteine and convert it into other substances, thereby reducing its harmful effects on blood vessels.

  6. Pregnancy and Fetal Development: Vitamin B6 is important for healthy pregnancy and fetal development. It helps support the growth and development of the fetus and may help alleviate symptoms of nausea and vomiting during pregnancy (morning sickness). Pregnant women may require higher levels of vitamin B6 to support the increased metabolic demands of pregnancy.

  7. Nerve Function: Vitamin B6 plays a role in maintaining healthy nerve function and may help alleviate symptoms of neuropathy or nerve damage. Some research suggests that vitamin B6 supplementation may have benefits for individuals with conditions such as carpal tunnel syndrome, diabetic neuropathy, or chemotherapy-induced neuropathy.

  8. Skin Health: Vitamin B6 is involved in the synthesis of collagen, a protein that provides structure and elasticity to the skin. Adequate vitamin B6 levels are necessary for maintaining healthy skin and may help alleviate symptoms of certain skin conditions such as dermatitis or eczema.

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Data Contradictions — Limits of Certainity

Impacted of Pyridoxine {Vitamin B6} On Probiotics

Rank Probiotic Impact
species Parabacteroides distasonis Reduces

Bacteria Impacted by Pyridoxine {Vitamin B6}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Dorea genus Decreases
0 2 Streptococcus genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Bacteroides genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Lachnospira genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Thomasclavelia genus Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Streptococcus pneumoniae species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Bacteroides fragilis species Decreases
0 1 Streptococcus pneumoniae G54 strain Decreases
0 1 Streptococcus pneumoniae TCH8431/19A strain Decreases
0 1 Streptococcus pneumoniae AP200 strain Decreases
0 1 Streptococcus pneumoniae Hungary19A-6 strain Decreases
0 1 Streptococcus pneumoniae 70585 strain Decreases
0 1 Streptococcus pneumoniae SPNA45 strain Decreases
0 1 Streptococcus pneumoniae JJA strain Decreases
0 1 Streptococcus pneumoniae CGSP14 strain Decreases
0 1 Streptococcus pneumoniae ST556 strain Decreases
0 1 Streptococcus pneumoniae INV200 strain Decreases
0 1 Streptococcus pneumoniae 670-6B strain Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of Pyridoxine {Vitamin B6} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.3 0.3
ADHD 1 1
Age-Related Macular Degeneration and Glaucoma 0.6 0.4 0.5
Allergic Rhinitis (Hay Fever) 2.4 0.7 2.43
Allergies 1.3 0.6 1.17
Allergy to milk products 0.3 0.7 -1.33
Alopecia (Hair Loss) 0.9 0.9
Alzheimer's disease 1.8 0.9 1
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.7 0.7
Ankylosing spondylitis 1.8 1.1 0.64
Anorexia Nervosa 0.7 0.9 -0.29
Antiphospholipid syndrome (APS) 0.8 0.8
Asthma 2.2 0.6 2.67
Atherosclerosis 0.6 0.6
Atrial fibrillation 1.9 0.7 1.71
Autism 2.2 2.6 -0.18
Autoimmune Disease 0.3 0.3
Barrett esophagus cancer 0.3 0.3 0
benign prostatic hyperplasia 0.3 -0.3
Biofilm 1.7 1.7
Bipolar Disorder 0.7 0.7
Brain Trauma 0.3 0.3 0
Breast Cancer 0.2 0.2
Cancer (General) 0.3 0.3
Carcinoma 2.1 1.3 0.62
Celiac Disease 0.6 1.6 -1.67
Cerebral Palsy 0.6 0.3 1
Chronic Fatigue Syndrome 1.1 1.7 -0.55
Chronic Kidney Disease 1.6 0.3 4.33
Chronic Lyme 0.3 -0.3
Chronic Obstructive Pulmonary Disease (COPD) 1.5 0.9 0.67
Chronic Urticaria (Hives) 0.3 0 0
Coagulation / Micro clot triggering bacteria 1.2 0.3 3
Cognitive Function 1.6 0.3 4.33
Colorectal Cancer 2.3 0.3 6.67
Constipation 0.6 0.6
Coronary artery disease 0.6 0.3 1
COVID-19 2.6 2.8 -0.08
Crohn's Disease 2.7 2 0.35
Cushing's Syndrome (hypercortisolism) 0.3 -0.3
cystic fibrosis 0.3 -0.3
d-lactic acidosis (one form of brain fog) 0.5 0.5
deep vein thrombosis 0.3 0.6 -1
Denture Wearers Oral Shifts 1 1
Depression 3 1.9 0.58
Dermatomyositis 0.3 0.3
Eczema 0.9 0.3 2
Endometriosis 1.6 0.3 4.33
Eosinophilic Esophagitis 0.3 0.3 0
Epilepsy 1.4 0.7 1
erectile dysfunction 1.4 1.4
Fibromyalgia 1.6 0.3 4.33
Functional constipation / chronic idiopathic constipation 1.3 0.7 0.86
gallstone disease (gsd) 1.3 0.3 3.33
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.5 0.6 -0.2
Generalized anxiety disorder 1.1 0.6 0.83
Glioblastoma 0.3 -0.3
Gout 0.6 0.6
Graves' disease 0.7 1.2 -0.71
Gulf War Syndrome 0.3 0 0
Halitosis 1.1 0.3 2.67
Hashimoto's thyroiditis 1.2 0.6 1
Heart Failure 1.6 1.6
hemorrhagic stroke 1.3 1.3
Hidradenitis Suppurativa 1.2 1.2
hyperglycemia 0.7 -0.7
hypertension (High Blood Pressure 1.9 0.7 1.71
Hypoxia 1.3 1.3
IgA nephropathy (IgAN) 1.3 0.3 3.33
Inflammatory Bowel Disease 2.5 1.5 0.67
Insomnia 1.2 0.9 0.33
Intelligence 0.3 0.3
Intracranial aneurysms 1 1
Irritable Bowel Syndrome 1.7 1.3 0.31
ischemic stroke 1 0.3 2.33
Liver Cirrhosis 1.9 1.4 0.36
Long COVID 2.4 1.9 0.26
Low bone mineral density 0.3 -0.3
Lung Cancer 0.6 -0.6
Mast Cell Issues / mastitis 0.5 0.5
ME/CFS with IBS 0.3 0.5 -0.67
ME/CFS without IBS 0.6 1.4 -1.33
membranous nephropathy 0.3 0.3
Menopause 0.3 0.3
Metabolic Syndrome 2.2 1.9 0.16
Mood Disorders 2.4 1.3 0.85
multiple chemical sensitivity [MCS] 0.3 0.3
Multiple Sclerosis 2 1.7 0.18
Multiple system atrophy (MSA) 0.4 0.4
myasthenia gravis 0.3 0.3
neuropathic pain 1 -1
Neuropathy (all types) 0.3 0.4 -0.33
neuropsychiatric disorders (PANDAS, PANS) 0.3 0.3
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.3 0.6 2.83
NonCeliac Gluten Sensitivity 0.3 0.3 0
Obesity 3.5 2.7 0.3
obsessive-compulsive disorder 1.3 1.4 -0.08
Osteoarthritis 1.4 0.6 1.33
Osteoporosis 0.3 1.2 -3
pancreatic cancer 0.5 0.3 0.67
Parkinson's Disease 1 2.9 -1.9
Polycystic ovary syndrome 1.9 0.6 2.17
Premenstrual dysphoric disorder 0.4 -0.4
primary biliary cholangitis 0.9 0.6 0.5
Primary sclerosing cholangitis 1.7 1 0.7
Psoriasis 0.6 1.1 -0.83
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.1 1.2 1.58
Schizophrenia 1.6 1 0.6
scoliosis 0.1 -0.1
sensorineural hearing loss 0.5 0.5
Sjögren syndrome 0.7 1.3 -0.86
Sleep Apnea 1.2 0.3 3
Slow gastric motility / Gastroparesis 0.3 0.3
Small Intestinal Bacterial Overgrowth (SIBO) 0.9 0.9
Stress / posttraumatic stress disorder 1.6 0.7 1.29
Systemic Lupus Erythematosus 1.6 0.9 0.78
Tic Disorder 0.3 0.6 -1
Tourette syndrome 0.9 0.3 2
Type 1 Diabetes 0.6 0.9 -0.5
Type 2 Diabetes 2.2 1.9 0.16
Ulcerative colitis 2.7 0.7 2.86
Unhealthy Ageing 2 0.4 4
Vitiligo 1.3 0.4 2.25

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