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🍽️ diphenhydramine hydrochloride,(prescription) [Can cause cognitive issues]

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  1. Antihistamine Effects: Diphenhydramine hydrochloride blocks the action of histamine, a substance in the body involved in allergic reactions. This action helps alleviate symptoms such as itching, sneezing, runny nose, and watery eyes associated with allergies.

  2. Sedative Effects: Diphenhydramine hydrochloride is known for its sedative properties, which can induce drowsiness and promote sleep. It is often included in over-the-counter sleep aids for its ability to help individuals fall asleep.

  3. Anticholinergic Effects: Diphenhydramine hydrochloride also has anticholinergic properties, meaning it blocks the action of acetylcholine, a neurotransmitter in the brain. This can lead to side effects such as dry mouth, blurred vision, constipation, urinary retention, and confusion, particularly in older adults.

  4. Cognitive Impairment: The anticholinergic effects of diphenhydramine hydrochloride can potentially cause cognitive impairment, especially in older adults. Long-term or high-dose use of anticholinergic medications has been associated with an increased risk of cognitive decline, dementia, and delirium. Therefore, caution should be exercised when using diphenhydramine hydrochloride, especially in older adults or individuals with pre-existing cognitive impairment.

  5. Fall Risk: The sedative and anticholinergic effects of diphenhydramine hydrochloride can also increase the risk of falls, particularly in older adults. This risk is further elevated when diphenhydramine is combined with other medications that have similar effects on cognition and balance.

  6. Other Considerations: Diphenhydramine hydrochloride may interact with other medications, including prescription drugs and over-the-counter products. It's essential to inform healthcare providers about all medications being taken to avoid potential interactions.

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Data Contradictions β€” Limits of Certainity

Impacted of diphenhydramine hydrochloride,(prescription) [Can cause cognitive issues] On Probiotics

Bacteria Impacted by diphenhydramine hydrochloride,(prescription) [Can cause cognitive issues]

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

Impact of diphenhydramine hydrochloride,(prescription) [Can cause cognitive issues] on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

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