AI Engines For more Details: Perplexity Kagi Labs You
Allergic Rhinitis: Chloropyramine hydrochloride is effective in alleviating symptoms of allergic rhinitis, including sneezing, itching, runny or stuffy nose, and postnasal drip. It works by blocking the action of histamine, a substance in the body that contributes to allergic symptoms.
Hives (Urticaria): It can also help relieve itching and reduce the size and number of hives in individuals experiencing allergic reactions or other causes of hives.
Allergic Conjunctivitis: Chloropyramine hydrochloride may be used to alleviate symptoms of allergic conjunctivitis, such as itchy, watery eyes and redness. By blocking histamine receptors in the eyes, it reduces these symptoms.
Insect Bites: Chloropyramine hydrochloride can be effective in relieving itching and discomfort associated with insect bites or stings.
Pruritus (Itching): In addition to allergic conditions, chloropyramine hydrochloride may be prescribed to alleviate itching associated with various dermatological conditions, such as eczema or contact dermatitis.
Motion Sickness: Chloropyramine hydrochloride has mild sedative effects and may be used to alleviate symptoms of motion sickness, such as nausea and vomiting.
Side Effects: Common side effects of chloropyramine hydrochloride may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and urinary retention. These side effects are usually mild and transient but can be more pronounced in some individuals.
Interactions: Chloropyramine hydrochloride may interact with other medications, such as central nervous system depressants, causing additive sedative effects. Individuals should inform their healthcare provider about all medications, supplements, and herbal products they are taking before starting chloropyramine hydrochloride therapy.
Contraindications: Chloropyramine hydrochloride is contraindicated in individuals with known hypersensitivity to the drug or other antihistamines of similar chemical structure. It should be used with caution in elderly individuals and those with certain medical conditions, such as glaucoma, urinary retention, or severe liver or kidney impairment.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Reduces |
| species | Anaerobutyricum hallii | Reduces |
| species | Blautia wexlerae | Reduces |
| species | Christensenella minuta | Reduces |
| species | Enterococcus faecium | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| species | Lactococcus cremoris | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| 📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 0 | 1 | Akkermansiaceae | family | Decreases |
| 1 | 0 | Akkermansia | genus | Decreases |
| 0 | 1 | Segatella | genus | Decreases |
| 0 | 1 | Agathobacter | genus | Decreases |
| 0 | 1 | Lacticaseibacillus | genus | Decreases |
| 0 | 1 | Coprococcus | genus | Decreases |
| 0 | 1 | Dorea | genus | Decreases |
| 0 | 1 | Wansuia | genus | Decreases |
| 0 | 1 | Anaerobutyricum | genus | Decreases |
| 0 | 1 | Komagataeibacter | genus | Decreases |
| 0 | 1 | Lacrimispora | genus | Decreases |
| 0 | 1 | Butyrivibrio | genus | Decreases |
| 0 | 1 | Catenibacterium | genus | Decreases |
| 0 | 1 | Enterocloster | genus | Decreases |
| 0 | 1 | Faecalitalea | genus | Decreases |
| 0 | 1 | Novisyntrophococcus | genus | Decreases |
| 0 | 1 | Treponema | genus | Decreases |
| 0 | 1 | Massilistercora | genus | Decreases |
| 0 | 1 | Eubacterium | genus | Decreases |
| 0 | 1 | Wujia | genus | Decreases |
| 0 | 1 | Ligilactobacillus | genus | Decreases |
| 0 | 1 | Ruminococcus | genus | Decreases |
| 0 | 1 | Qiania | genus | Decreases |
| 0 | 1 | Leyella | genus | Decreases |
| 0 | 1 | Lachnoanaerobaculum | genus | Decreases |
| 0 | 1 | Vescimonas | genus | Decreases |
| 0 | 1 | Subdoligranulum | genus | Decreases |
| 0 | 1 | Chordicoccus | genus | Decreases |
| 0 | 1 | Intestinibaculum | genus | Decreases |
| 0 | 1 | Maliibacterium | genus | Decreases |
| 0 | 1 | Oscillibacter | genus | Decreases |
| 0 | 1 | Phocaeicola | genus | Decreases |
| 0 | 1 | Bacteroides | genus | Decreases |
| 0 | 1 | environmental samples | no rank | Decreases |
| 0 | 1 | unclassified Akkermansia | no rank | Decreases |
| 1 | 0 | Lacticaseibacillus paracasei | species | Decreases |
| 1 | 0 | Agathobacter rectalis | species | Decreases |
| 1 | 0 | Akkermansia muciniphila | species | Decreases |
| 1 | 0 | Segatella copri | species | Decreases |
| 1 | 0 | Coprococcus comes | species | Decreases |
| 0 | 1 | Dorea longicatena | species | Decreases |
| 0 | 1 | Coprococcus catus | species | Decreases |
| 0 | 1 | Blautia obeum | species | Decreases |
| 0 | 1 | Dorea formicigenerans | species | Decreases |
| 0 | 1 | Wansuia hejianensis | species | Decreases |
| 0 | 1 | Anaerobutyricum hallii | species | Decreases |
| 0 | 1 | Blautia sp. SC05B48 | species | Decreases |
| 0 | 1 | Lacrimispora saccharolytica | species | Decreases |
| 0 | 1 | Ligilactobacillus ruminis | species | Decreases |
| 0 | 1 | Komagataeibacter oboediens | species | Decreases |
| 0 | 1 | [Ruminococcus] lactaris | species | Decreases |
| 0 | 1 | [Ruminococcus] torques | species | Decreases |
| 0 | 1 | Eubacterium ventriosum | species | Decreases |
| 0 | 1 | Clostridium sp. M62/1 | species | Decreases |
| 0 | 1 | Coprococcus eutactus | species | Decreases |
| 0 | 1 | Lachnoanaerobaculum gingivalis | species | Decreases |
| 0 | 1 | Blautia liquoris | species | Decreases |
| 1 | 0 | Enterocloster bolteae | species | Decreases |
| 0 | 1 | Clostridium sp. SY8519 | species | Decreases |
| 0 | 1 | Butyrivibrio crossotus | species | Decreases |
| 0 | 1 | Coprococcus sp. ART55/1 | species | Decreases |
| 0 | 1 | Catenibacterium mitsuokai | species | Decreases |
| 0 | 1 | Faecalibacterium duncaniae | species | Decreases |
| 0 | 1 | Faecalitalea cylindroides | species | Decreases |
| 0 | 1 | Massilistercora timonensis | species | Decreases |
| 0 | 1 | Segatella bryantii | species | Decreases |
| 0 | 1 | Eubacterium sp. MSJ-33 | species | Decreases |
| 0 | 1 | Treponema peruense | species | Decreases |
| 0 | 1 | Novisyntrophococcus fermenticellae | species | Decreases |
| 0 | 1 | Catenibacterium sp. co_0103 | species | Decreases |
| 0 | 1 | Qiania dongpingensis | species | Decreases |
| 0 | 1 | Faecalibacillus intestinalis | species | Decreases |
| 0 | 1 | Roseburia hominis | species | Decreases |
| 0 | 1 | [Clostridium] hylemonae | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I2-3-92 | species | Decreases |
| 0 | 1 | Faecalibacterium sp. HTF-F | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I4-1-79 | species | Decreases |
| 0 | 1 | Faecalibacterium sp. IP-3-29 | species | Decreases |
| 0 | 1 | Intestinibaculum porci | species | Decreases |
| 0 | 1 | Leyella stercorea | species | Decreases |
| 0 | 1 | Clostridium cadaveris | species | Decreases |
| 0 | 1 | Anaerostipes hadrus | species | Decreases |
| 0 | 1 | Pseudobutyrivibrio xylanivorans | species | Decreases |
| 0 | 1 | Lactococcus cremoris | species | Decreases |
| 0 | 1 | Vescimonas coprocola | species | Decreases |
| 0 | 1 | Lachnoclostridium phocaeense | species | Decreases |
| 0 | 1 | Marvinbryantia formatexigens | species | Decreases |
| 0 | 1 | Streptococcus suis | species | Decreases |
| 0 | 1 | Wujia chipingensis | species | Decreases |
| 0 | 1 | Lawsonibacter asaccharolyticus | species | Decreases |
| 0 | 1 | Longicatena caecimuris | species | Decreases |
| 0 | 1 | Subdoligranulum variabile | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I3-3-89 | species | Decreases |
| 0 | 1 | Ruminococcus bicirculans (ex Wegman et al. 2014) | species | Decreases |
| 0 | 1 | Mageeibacillus indolicus | species | Decreases |
| 0 | 1 | Faecalibacterium sp. IP-1-18 | species | Decreases |
| 0 | 1 | Christensenella minuta | species | Decreases |
| 0 | 1 | Solibaculum mannosilyticum | species | Decreases |
| 0 | 1 | Adlercreutzia equolifaciens | species | Decreases |
| 0 | 1 | Chordicoccus furentiruminis | species | Decreases |
| 0 | 1 | Vescimonas fastidiosa | species | Decreases |
| 0 | 1 | Maliibacterium massiliense | species | Decreases |
| 0 | 1 | Oscillibacter hominis | species | Decreases |
| 0 | 1 | Monoglobus pectinilyticus | species | Decreases |
| 0 | 1 | Ruminococcus gauvreauii | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I4-3-84 | species | Decreases |
| 0 | 1 | Roseburia rectibacter | species | Decreases |
| 0 | 1 | Adlercreutzia hattorii | species | Decreases |
| 0 | 1 | Roseburia intestinalis | species | Decreases |
| 0 | 1 | Ruminococcus champanellensis | species | Decreases |
| 0 | 1 | Fannyhessea vaginae | species | Decreases |
| 0 | 1 | Blautia wexlerae | species | Decreases |
| 0 | 1 | Bacillus paralicheniformis | species | Decreases |
| 0 | 1 | Faecalibacterium sp. I3-3-33 | species | Decreases |
| 0 | 1 | Flintibacter sp. KGMB00164 | species | Decreases |
| 0 | 1 | Eubacterium sp. c-25 | species | Decreases |
| 0 | 1 | Parvimonas micra | species | Decreases |
| 0 | 1 | Enterococcus cecorum | species | Decreases |
| 0 | 1 | Faecalibaculum rodentium | species | Decreases |
| 0 | 1 | Enterococcus faecium | species | Decreases |
| 0 | 1 | Ruminococcus bovis | species | Decreases |
| 0 | 1 | Mogibacterium diversum | species | Decreases |
| 0 | 1 | Simiaoa sunii | species | Decreases |
| 0 | 1 | Treponema denticola | species | Decreases |
| 1 | 0 | Phocaeicola vulgatus | species | Decreases |
| 0 | 1 | Akkermansia glycaniphila | species | Decreases |
| 0 | 1 | Akkermansia massiliensis | species | Decreases |
| 0 | 1 | Candidatus Akkermansia intestinavium | species | Decreases |
| 0 | 1 | Prevotella intermedia | species | Decreases |
| 0 | 1 | Intestinimonas butyriciproducens | species | Decreases |
| 0 | 1 | Actinomyces oris | species | Decreases |
| 0 | 1 | Lachnospira eligens | species | Decreases |
| 0 | 1 | Emergencia timonensis | species | Decreases |
| 0 | 1 | Eubacterium limosum | species | Decreases |
| 0 | 1 | Leyella lascolaii | species | Decreases |
| 0 | 1 | Anaerotruncus colihominis | species | Decreases |
| 0 | 1 | Ruminococcus albus | species | Decreases |
| 0 | 1 | Phascolarctobacterium sp. Marseille-Q4147 | species | Decreases |
| 0 | 1 | Turicibacter bilis | species | Decreases |
| 0 | 1 | Corynebacterium durum | species | Decreases |
| 0 | 1 | Eubacterium maltosivorans | species | Decreases |
| 0 | 1 | [Eubacterium] hominis | species | Decreases |
| 0 | 1 | Phascolarctobacterium succinatutens | species | Decreases |
| 0 | 1 | Acutalibacter muris | species | Decreases |
| 0 | 1 | Butyrivibrio fibrisolvens | species | Decreases |
| 0 | 1 | Pusillibacter faecalis | species | Decreases |
| 0 | 1 | Clostridioides difficile | species | Decreases |
| 0 | 1 | Eubacterium callanderi | species | Decreases |
| 0 | 1 | Olsenella sp. oral taxon 807 | species | Decreases |
| 0 | 1 | Romboutsia ilealis | species | Decreases |
| 0 | 1 | Butyricicoccus sp. GAM44 | species | Decreases |
| 0 | 1 | Paraprevotella clara | species | Decreases |
| 0 | 1 | Prevotella bivia | species | Decreases |
| 0 | 1 | Ruthenibacterium lactatiformans | species | Decreases |
| 0 | 1 | Alistipes communis | species | Decreases |
| 0 | 1 | Phoenicibacter congonensis | species | Decreases |
| 0 | 1 | Actinomyces naeslundii | species | Decreases |
| 0 | 1 | Blautia pseudococcoides | species | Decreases |
| 0 | 1 | Prevotella dentalis | species | Decreases |
| 1 | 0 | Bacteroides thetaiotaomicron | species | Decreases |
| 1 | 0 | Bacteroides fragilis | species | Decreases |
| 0 | 1 | Lacticaseibacillus paracasei subsp. paracasei | subspecies | Decreases |
| 0 | 1 | Lacticaseibacillus paracasei subsp. tolerans | subspecies | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.2 | 0.2 | |
| ADHD | 0.5 | 1 | -1 |
| Age-Related Macular Degeneration and Glaucoma | 0.4 | 0.4 | |
| Allergic Rhinitis (Hay Fever) | 0.5 | 0.8 | -0.6 |
| Allergies | 1.8 | 1.9 | -0.06 |
| Allergy to milk products | 1.1 | 0.4 | 1.75 |
| Alopecia (Hair Loss) | 0.3 | 0.2 | 0.5 |
| Alzheimer's disease | 2.4 | 2.5 | -0.04 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 1.9 | 0.9 | 1.11 |
| Ankylosing spondylitis | 1.3 | 0.2 | 5.5 |
| Anorexia Nervosa | 0.1 | 0.6 | -5 |
| Antiphospholipid syndrome (APS) | 0.2 | 0.2 | |
| Asthma | 0.3 | 1.2 | -3 |
| Atherosclerosis | 0.6 | 0.7 | -0.17 |
| Atrial fibrillation | 1 | 1.5 | -0.5 |
| Autism | 3.4 | 3.5 | -0.03 |
| benign prostatic hyperplasia | 0 | 0 | |
| Bipolar Disorder | 0.2 | 0.4 | -1 |
| Brain Trauma | 0.3 | 0.2 | 0.5 |
| Cancer (General) | 0.8 | -0.8 | |
| Carcinoma | 0.9 | 0.8 | 0.13 |
| Celiac Disease | 0.5 | 0.8 | -0.6 |
| Cerebral Palsy | 0.5 | 0.1 | 4 |
| Chronic Fatigue Syndrome | 1.1 | 3.7 | -2.36 |
| Chronic Kidney Disease | 1.2 | 2.2 | -0.83 |
| Chronic Lyme | 0.1 | 0 | 0 |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.4 | 0.4 | 0 |
| Chronic Urticaria (Hives) | 1.2 | -1.2 | |
| Coagulation / Micro clot triggering bacteria | 0.5 | -0.5 | |
| Cognitive Function | 0.4 | 0.1 | 3 |
| Colorectal Cancer | 1.6 | 0.7 | 1.29 |
| Constipation | 0.3 | 0.3 | |
| Coronary artery disease | 1 | 1.7 | -0.7 |
| COVID-19 | 2.1 | 6.5 | -2.1 |
| Crohn's Disease | 2 | 3.4 | -0.7 |
| Cushing's Syndrome (hypercortisolism) | 0.2 | -0.2 | |
| cystic fibrosis | 0 | 0 | |
| deep vein thrombosis | 0.9 | 0.5 | 0.8 |
| Denture Wearers Oral Shifts | 0.1 | 0.1 | |
| Depression | 3.1 | 5 | -0.61 |
| Eczema | 0.1 | -0.1 | |
| Endometriosis | 0.7 | 0.4 | 0.75 |
| Epilepsy | 0.7 | 1.1 | -0.57 |
| erectile dysfunction | 0.1 | 0.1 | |
| Fibromyalgia | 0.4 | 1.3 | -2.25 |
| Functional constipation / chronic idiopathic constipation | 0.9 | 1.6 | -0.78 |
| gallstone disease (gsd) | 0.5 | 0.5 | 0 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.2 | 1 | -4 |
| Generalized anxiety disorder | 0.7 | 0.8 | -0.14 |
| Glioblastoma | 0.1 | 0.1 | |
| Gout | 0.5 | 0.7 | -0.4 |
| Graves' disease | 0.1 | 0.5 | -4 |
| Gulf War Syndrome | 0.3 | 1.1 | -2.67 |
| Halitosis | 0.3 | 0.3 | |
| Hashimoto's thyroiditis | 1.4 | 0.8 | 0.75 |
| Heart Failure | 1.1 | 1.7 | -0.55 |
| hemorrhagic stroke | 0.3 | 0.3 | |
| Hidradenitis Suppurativa | 0 | 0 | |
| High Histamine/low DAO | 0.1 | -0.1 | |
| hypercholesterolemia (High Cholesterol) | 0.7 | -0.7 | |
| hyperglycemia | 0.2 | 1 | -4 |
| Hyperlipidemia (High Blood Fats) | 0.6 | 0.6 | |
| hypertension (High Blood Pressure | 1.8 | 1.7 | 0.06 |
| Hypothyroidism | 0.7 | 0.5 | 0.4 |
| Hypoxia | 0.7 | 0.7 | |
| IgA nephropathy (IgAN) | 0.3 | 1.3 | -3.33 |
| Inflammatory Bowel Disease | 1.6 | 4.6 | -1.87 |
| Insomnia | 1 | 1.5 | -0.5 |
| Intelligence | 0.3 | 0.9 | -2 |
| Intracranial aneurysms | 0.3 | 0.4 | -0.33 |
| Irritable Bowel Syndrome | 2.1 | 2 | 0.05 |
| ischemic stroke | 0.1 | 0.4 | -3 |
| Juvenile idiopathic arthritis | 0.1 | -0.1 | |
| Liver Cirrhosis | 2.1 | 2.3 | -0.1 |
| Long COVID | 2.8 | 2.9 | -0.04 |
| Low bone mineral density | 0.8 | -0.8 | |
| Lung Cancer | 1.2 | -1.2 | |
| Mast Cell Issues / mastitis | 0.4 | -0.4 | |
| ME/CFS with IBS | 0.2 | 2.3 | -10.5 |
| ME/CFS without IBS | 0.4 | 0.9 | -1.25 |
| Menopause | 0.3 | 0.5 | -0.67 |
| Metabolic Syndrome | 1.9 | 3.1 | -0.63 |
| Mood Disorders | 3.6 | 3.9 | -0.08 |
| multiple chemical sensitivity [MCS] | 0.4 | 0.4 | |
| Multiple Sclerosis | 1.5 | 2.5 | -0.67 |
| Multiple system atrophy (MSA) | 1.2 | 0.1 | 11 |
| myasthenia gravis | 0.1 | -0.1 | |
| neuropathic pain | 0.6 | -0.6 | |
| Neuropathy (all types) | 0.4 | 0.4 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 1.4 | 3.1 | -1.21 |
| NonCeliac Gluten Sensitivity | 0.6 | 0 | 0 |
| Obesity | 4.7 | 3.9 | 0.21 |
| obsessive-compulsive disorder | 1.3 | 2.4 | -0.85 |
| Osteoarthritis | 0.6 | 0.9 | -0.5 |
| Osteoporosis | 0.1 | 0.9 | -8 |
| Parkinson's Disease | 3.3 | 3.7 | -0.12 |
| Polycystic ovary syndrome | 1.2 | 0.5 | 1.4 |
| Postural orthostatic tachycardia syndrome | 0.3 | -0.3 | |
| primary biliary cholangitis | 0.3 | 0.3 | |
| Primary sclerosing cholangitis | 0.2 | 1.3 | -5.5 |
| Psoriasis | 0.9 | 2.2 | -1.44 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 2.5 | 1.2 | 1.08 |
| Rosacea | 0.4 | 0.4 | |
| Schizophrenia | 1.6 | 0.9 | 0.78 |
| scoliosis | 0.7 | 0.2 | 2.5 |
| sensorineural hearing loss | 0.5 | 0.5 | |
| Sjögren syndrome | 0.6 | 0.7 | -0.17 |
| Sleep Apnea | 0.8 | 0.3 | 1.67 |
| Slow gastric motility / Gastroparesis | 0.2 | 0.2 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.6 | 0.6 | |
| Stress / posttraumatic stress disorder | 0.6 | 0.9 | -0.5 |
| Systemic Lupus Erythematosus | 0.6 | 0.4 | 0.5 |
| Tic Disorder | 0.2 | 1.5 | -6.5 |
| Tourette syndrome | 0.6 | 0 | 0 |
| Type 1 Diabetes | 1.3 | 0.7 | 0.86 |
| Type 2 Diabetes | 3 | 2.7 | 0.11 |
| Ulcerative colitis | 1.3 | 3.3 | -1.54 |
| Unhealthy Ageing | 1.3 | 1.5 | -0.15 |
| Vitiligo | 0.3 | 1 | -2.33 |
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