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🍽️ ifosfamide,(prescription)

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  1. Myelosuppression: One of the most common adverse effects of ifosfamide is bone marrow suppression, which can lead to decreased production of red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). This can increase the risk of infections, bleeding, and fatigue.
  2. Nausea and Vomiting: Ifosfamide can cause significant gastrointestinal side effects, including nausea, vomiting, and loss of appetite. These symptoms may be severe and require antiemetic medications for management.
  3. Hemorrhagic Cystitis: Hemorrhagic cystitis, characterized by inflammation and bleeding of the bladder, is a well-known complication of ifosfamide therapy. Mesna, a medication that helps protect the bladder lining, is often co-administered with ifosfamide to reduce the risk of this side effect.
  4. Neurotoxicity: Ifosfamide can cause neurotoxicity, leading to symptoms such as confusion, disorientation, hallucinations, and seizures. These symptoms may be reversible upon discontinuation of the drug but can be dose-limiting.
  5. Renal Toxicity: Ifosfamide can impair kidney function, leading to electrolyte imbalances, renal tubular acidosis, and renal failure in severe cases. Adequate hydration and monitoring of renal function are essential during ifosfamide therapy.
  6. Alopecia: Hair loss (alopecia) is a common side effect of ifosfamide chemotherapy. Hair loss is usually temporary and reversible upon completion of treatment.
  7. Mucositis: Ifosfamide can cause inflammation and ulceration of the mucous membranes lining the mouth and gastrointestinal tract, leading to mucositis. This can result in pain, difficulty swallowing, and increased susceptibility to infections.
  8. Skin Toxicity: Some patients may experience skin reactions such as rash, itching, or photosensitivity (increased sensitivity to sunlight) while receiving ifosfamide therapy.
  9. Cardiotoxicity: Ifosfamide has been associated with cardiotoxic effects, including arrhythmias, myocardial dysfunction, and heart failure, although these are less common than other adverse effects.
  10. Secondary Malignancies: Long-term use of ifosfamide may increase the risk of developing secondary malignancies, including leukemia and other cancers.
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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of ifosfamide,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium longum Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Escherichia coli Reduces
species Lactococcus cremoris Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by ifosfamide,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?

📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Thomasclavelia genus Decreases
0 1 Collinsella genus Decreases
0 1 Blautia genus Decreases
0 1 Veillonella genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Eggerthella genus Decreases
0 1 Roseburia genus Decreases
0 1 Coprococcus genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Odoribacter genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Dorea genus Decreases
0 1 Bacteroides genus Decreases
0 1 Lachnospira genus Decreases
0 1 Parolsenella genus Decreases
0 1 Clostridioides genus Decreases
0 1 Agathobacter genus Decreases
0 1 Streptococcus genus Decreases
1 0 Akkermansia genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Enterocloster genus Decreases
0 1 Escherichia genus Decreases
0 1 Clostridium genus Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Blautia obeum species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Roseburia hominis species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Veillonella parvula species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Coprococcus comes species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Dorea formicigenerans species Decreases
0 1 Veillonella rodentium species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Veillonella dispar species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Veillonella nakazawae species Decreases
1 0 Clostridioides difficile species Decreases
0 1 Coprococcus catus species Decreases
0 1 Veillonella rogosae species Decreases
0 1 Bifidobacterium breve species Decreases
1 0 Agathobacter rectalis species Decreases
0 1 Dorea longicatena species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Parolsenella catena species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Wansuia hejianensis species Decreases
1 0 Akkermansia muciniphila species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Veillonella atypica species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Blautia liquoris species Decreases
0 1 Wujia chipingensis species Decreases
1 0 Lacrimispora saccharolytica species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Actinomyces oris species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
1 0 Enterocloster bolteae species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Christensenella minuta species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Treponema denticola species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Parvimonas micra species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Streptococcus suis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Bacteroides sp. M10 species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Treponema peruense species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Butyricimonas faecalis species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Alistipes ihumii species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Alistipes communis species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Escherichia coli species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases

Impact of ifosfamide,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0 0
Acne 0.2 -0.2
ADHD 2.4 0.8 2
Age-Related Macular Degeneration and Glaucoma 0.6 0.6
Allergic Rhinitis (Hay Fever) 1.2 1.7 -0.42
Allergies 4 1.6 1.5
Allergy to milk products 1.2 0.6 1
Alopecia (Hair Loss) 1 0.1 9
Alzheimer's disease 2.8 4.2 -0.5
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.4 0.4 2.5
Ankylosing spondylitis 2.1 0.5 3.2
Anorexia Nervosa 0.9 1.6 -0.78
Antiphospholipid syndrome (APS) 0.4 0.4
Asthma 3.2 1.7 0.88
Atherosclerosis 1.3 1 0.3
Atrial fibrillation 2.1 0.6 2.5
Autism 5 4.2 0.19
Autoimmune Disease 0.3 0.5 -0.67
Barrett esophagus cancer 0.4 0.1 3
benign prostatic hyperplasia 0 0.1 0
Biofilm 0.7 0.7
Bipolar Disorder 0.7 1.3 -0.86
Brain Trauma 0.8 0.8 0
Breast Cancer 0 0
Cancer (General) 0.6 1.1 -0.83
Carcinoma 2.2 1.8 0.22
Celiac Disease 1.4 2.4 -0.71
Cerebral Palsy 0.9 1 -0.11
Chronic Fatigue Syndrome 3.2 4.1 -0.28
Chronic Kidney Disease 2.4 2.3 0.04
Chronic Lyme 0.2 0.4 -1
Chronic Obstructive Pulmonary Disease (COPD) 1 1.1 -0.1
Chronic Urticaria (Hives) 0.5 0.2 1.5
Coagulation / Micro clot triggering bacteria 0.1 1 -9
Cognitive Function 1.3 0.8 0.63
Colorectal Cancer 2.5 1.3 0.92
Constipation 0.5 0.7 -0.4
Coronary artery disease 1 2.1 -1.1
COVID-19 6.4 7.8 -0.22
Crohn's Disease 3.2 3.3 -0.03
Cushing's Syndrome (hypercortisolism) 0.1 -0.1
cystic fibrosis 0.1 1.5 -14
d-lactic acidosis (one form of brain fog) 0 0
deep vein thrombosis 0.4 0.7 -0.75
Denture Wearers Oral Shifts 0.8 0.8
Depression 5.4 6.2 -0.15
Dermatomyositis 0.1 0.2 -1
Eczema 0.5 0.8 -0.6
Endometriosis 1.4 1.5 -0.07
Eosinophilic Esophagitis 0.4 -0.4
Epilepsy 1.6 1 0.6
erectile dysfunction 0.2 0.2 0
Fibromyalgia 2 0.9 1.22
Functional constipation / chronic idiopathic constipation 2.5 2.2 0.14
gallstone disease (gsd) 1.2 0.6 1
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.4 1.5 -2.75
Generalized anxiety disorder 1.3 1.3 0
giant cell arteritis 0 0
Glioblastoma 0.1 -0.1
Gout 1 0.3 2.33
Graves' disease 1.4 2.4 -0.71
Gulf War Syndrome 0.8 0.5 0.6
Halitosis 0.6 0.1 5
Hashimoto's thyroiditis 2.7 1.2 1.25
Heart Failure 1.2 1.5 -0.25
hemorrhagic stroke 0.2 0.2
Hidradenitis Suppurativa 0.4 0.4 0
High Histamine/low DAO 0.3 0.4 -0.33
hypercholesterolemia (High Cholesterol) 0.3 0.2 0.5
hyperglycemia 0.8 1 -0.25
Hyperlipidemia (High Blood Fats) 0.7 0.4 0.75
hypersomnia 0.9 -0.9
hypertension (High Blood Pressure 2.7 3.7 -0.37
Hypothyroidism 0.1 1.2 -11
Hypoxia 0.6 0.6
IgA nephropathy (IgAN) 0.7 2.4 -2.43
Inflammatory Bowel Disease 4.6 6.2 -0.35
Insomnia 1.6 1.9 -0.19
Intelligence 0.7 0.7
Intracranial aneurysms 0.8 0.7 0.14
Irritable Bowel Syndrome 4 2.7 0.48
ischemic stroke 2 0.5 3
Liver Cirrhosis 4.1 2 1.05
Long COVID 4.2 5.8 -0.38
Low bone mineral density 0.9 -0.9
Lung Cancer 0 1.1 0
Lymphoma 0 0
Mast Cell Issues / mastitis 0.1 0.7 -6
ME/CFS with IBS 0.2 2.3 -10.5
ME/CFS without IBS 1.1 1.1 0
membranous nephropathy 0.1 0.1
Menopause 1.8 0.5 2.6
Metabolic Syndrome 3.6 4.4 -0.22
Mood Disorders 5.7 5.1 0.12
multiple chemical sensitivity [MCS] 0.6 0.4 0.5
Multiple Sclerosis 3.6 2.7 0.33
Multiple system atrophy (MSA) 1.1 0.8 0.38
myasthenia gravis 0.1 0.3 -2
neuropathic pain 0.3 1.8 -5
Neuropathy (all types) 0.9 0.7 0.29
neuropsychiatric disorders (PANDAS, PANS) 0.3 0.3
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.3 3.9 -0.18
NonCeliac Gluten Sensitivity 1.7 0.4 3.25
Obesity 6.3 4.2 0.5
obsessive-compulsive disorder 2.7 2.4 0.13
Osteoarthritis 1.6 0.9 0.78
Osteoporosis 1.3 1.2 0.08
pancreatic cancer 0.3 0.1 2
Parkinson's Disease 5.3 4 0.32
Polycystic ovary syndrome 2.6 2 0.3
Postural orthostatic tachycardia syndrome 0 0.5 0
Premenstrual dysphoric disorder 1.1 1.1
primary biliary cholangitis 0.6 0.5 0.2
Primary sclerosing cholangitis 1.7 1.8 -0.06
Psoriasis 2.3 1 1.3
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.7 2.6 0.81
Rosacea 1.1 0.3 2.67
Schizophrenia 4.6 2.1 1.19
scoliosis 0.4 0.5 -0.25
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 1.8 1.5 0.2
Sleep Apnea 1.3 1.3 0
Slow gastric motility / Gastroparesis 0.7 0.2 2.5
Small Intestinal Bacterial Overgrowth (SIBO) 0.9 0.5 0.8
Stress / posttraumatic stress disorder 0.9 2 -1.22
Systemic Lupus Erythematosus 1.8 1.6 0.13
Tic Disorder 0.5 1.1 -1.2
Tourette syndrome 0.3 0.1 2
Type 1 Diabetes 2.1 2.3 -0.1
Type 2 Diabetes 3.9 3 0.3
Ulcerative colitis 2.3 3.1 -0.35
Unhealthy Ageing 2.3 1.2 0.92
Vitiligo 0.8 0.9 -0.13

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