🍽️ paroxetine hydrochloride,(prescription)

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Depression: Paroxetine hydrochloride is primarily prescribed for the treatment of depression. It works by increasing the levels of serotonin, a neurotransmitter, in the brain, which helps improve mood and alleviate depressive symptoms.
Anxiety Disorders: Paroxetine hydrochloride is also used to treat various anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder, and obsessive-compulsive disorder (OCD).
Premenstrual Dysphoric Disorder (PMDD): Paroxetine hydrochloride may be prescribed to manage symptoms of PMDD, a severe form of premenstrual syndrome (PMS), such as mood swings, irritability, and physical symptoms.
Post-Traumatic Stress Disorder (PTSD): Paroxetine hydrochloride is sometimes used off-label to treat symptoms of PTSD, such as intrusive thoughts, flashbacks, nightmares, and hypervigilance.
Other Conditions: Paroxetine hydrochloride may also be prescribed off-label for conditions such as eating disorders, certain types of chronic pain, and menopausal symptoms.
Side Effects: Common side effects of paroxetine hydrochloride may include nausea, drowsiness, dry mouth, constipation, sweating, sexual dysfunction, and weight changes. These side effects are usually mild and may diminish over time. However, some individuals may experience more severe side effects or allergic reactions, such as rash, swelling, or difficulty breathing, which require immediate medical attention.
Withdrawal Symptoms: Discontinuing paroxetine hydrochloride abruptly or too rapidly may lead to withdrawal symptoms, commonly referred to as "discontinuation syndrome." These symptoms may include dizziness, headache, nausea, fatigue, irritability, and flu-like symptoms. It's essential to taper off the medication gradually under the supervision of a healthcare professional to minimize withdrawal effects.
Suicidal Thoughts and Behavior: Like other antidepressants, paroxetine hydrochloride may increase the risk of suicidal thoughts or behaviors, especially in children, adolescents, and young adults. Close monitoring is necessary, particularly when starting the medication or adjusting the dosage.
Serotonin Syndrome: In rare cases, the use of paroxetine hydrochloride may lead to serotonin syndrome, a potentially life-threatening condition characterized by dangerously high levels of serotonin in the brain. Symptoms may include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, shivering, muscle stiffness, tremors, and loss of coordination. Seek immediate medical attention if you experience any of these symptoms.
Drug Interactions: Paroxetine hydrochloride can interact with other medications, including other antidepressants, certain pain medications, migraine drugs, blood thinners, and herbal supplements like St. John's wort. It's crucial to inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.
Pregnancy and Breastfeeding: The use of paroxetine hydrochloride during pregnancy may be associated with an increased risk of certain birth defects and complications, particularly if used during the first trimester. It may also pass into breast milk and potentially affect the nursing infant. If you are pregnant or breastfeeding, discuss the risks and benefits of using paroxetine hydrochloride with your healthcare provider.
Liver and Kidney Function: Paroxetine hydrochloride should be used with caution in individuals with impaired liver or kidney function, as the dosage may need to be adjusted based on the severity of impairment.

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Data Contradictions — Limits of Certainity

Impacted of paroxetine hydrochloride,(prescription) On Probiotics

Rank	Probiotic	Impact
genus	Bifidobacterium	Reduces
species	Akkermansia muciniphila	Reduces
species	Bifidobacterium longum	Reduces
species	Escherichia coli	Reduces
species	Lacticaseibacillus paracasei	Reduces
subspecies	Bifidobacterium longum subsp. infantis	Reduces
subspecies	Bifidobacterium longum subsp. longum	Reduces

Bacteria Impacted by paroxetine hydrochloride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations	👪👶 Indirect Citations	Taxonomy	Rank	Effect
0	1	Cryptococcaceae	family	Decreases
0	1	Akkermansiaceae	family	Decreases
1	0	Cryptococcus	genus	Decreases
0	1	Agathobacter	genus	Decreases
0	1	Lacticaseibacillus	genus	Decreases
0	1	Segatella	genus	Decreases
0	1	Escherichia	genus	Decreases
0	1	Staphylococcus	genus	Decreases
0	1	Collinsella	genus	Decreases
0	1	Clostridioides	genus	Decreases
0	1	Shigella	genus	Decreases
1	0	Akkermansia	genus	Decreases
0	1	Mediterraneibacter	genus	Decreases
0	1	Lachnospira	genus	Decreases
0	1	Leyella	genus	Decreases
0	1	Coprococcus	genus	Decreases
0	1	Blautia	genus	Decreases
0	1	Roseburia	genus	Decreases
0	1	Eggerthella	genus	Decreases
0	1	Thomasclavelia	genus	Decreases
0	1	Bacteroides	genus	Decreases
0	1	Bifidobacterium	genus	Decreases
0	1	Lacrimispora	genus	Decreases
0	1	Escherichia coli O1:K1:H7	no rank	Decreases
0	1	Escherichia coli O139:H1	no rank	Decreases
0	1	Escherichia coli O141:H4	no rank	Decreases
0	1	Escherichia coli O145:H34	no rank	Decreases
0	1	Escherichia coli O15:H12	no rank	Decreases
0	1	Escherichia coli O155:H21	no rank	Decreases
0	1	Escherichia coli O158:H23	no rank	Decreases
0	1	Escherichia coli O16:H48	no rank	Decreases
0	1	Escherichia coli O170:H18	no rank	Decreases
0	1	Escherichia coli O18ac:H14	no rank	Decreases
0	1	Escherichia coli O19:H7	no rank	Decreases
0	1	Escherichia coli O2:K1:H4	no rank	Decreases
0	1	Escherichia coli O2:K1:H5	no rank	Decreases
0	1	Escherichia coli O2:K1:H7	no rank	Decreases
0	1	Escherichia coli O20:H12	no rank	Decreases
0	1	Escherichia coli O25:H16	no rank	Decreases
0	1	Escherichia coli O55:H7	no rank	Decreases
0	1	Escherichia coli O68:H12	no rank	Decreases
0	1	Escherichia coli O7:H15	no rank	Decreases
0	1	Escherichia coli O78:H51	no rank	Decreases
0	1	Escherichia coli O80:H26	no rank	Decreases
0	1	Escherichia coli O84:H7	no rank	Decreases
0	1	Escherichia coli O85:H1	no rank	Decreases
0	1	unclassified Cryptococcus (in: basidiomycete fungi)	no rank	Decreases
0	1	environmental samples	no rank	Decreases
0	1	unclassified Akkermansia	no rank	Decreases
0	1	Escherichia coli O103	serogroup	Decreases
0	1	Escherichia coli O111	serogroup	Decreases
0	1	Escherichia coli O119	serogroup	Decreases
0	1	Escherichia coli O121	serogroup	Decreases
0	1	Escherichia coli O145	serogroup	Decreases
0	1	Escherichia coli O155	serogroup	Decreases
0	1	Escherichia coli O157	serogroup	Decreases
0	1	Escherichia coli O177	serogroup	Decreases
0	1	Escherichia coli O26	serogroup	Decreases
0	1	Escherichia coli O3	serogroup	Decreases
0	1	Escherichia coli O43	serogroup	Decreases
0	1	Escherichia coli O5	serogroup	Decreases
0	1	Escherichia coli O78	serogroup	Decreases
0	1	Escherichia coli O86	serogroup	Decreases
0	1	Escherichia coli O91	serogroup	Decreases
0	1	Escherichia coli H20	serotype	Decreases
0	1	Escherichia coli O1:H42	serotype	Decreases
0	1	Escherichia coli O1:HNT	serotype	Decreases
0	1	Escherichia coli O10:H32	serotype	Decreases
0	1	Escherichia coli O10:K5(L):H4	serotype	Decreases
0	1	Escherichia coli O100:H21	serotype	Decreases
0	1	Escherichia coli O103:H11	serotype	Decreases
0	1	Escherichia coli O103:H2	serotype	Decreases
0	1	Escherichia coli O103:H25	serotype	Decreases
0	1	Escherichia coli O104:H21	serotype	Decreases
0	1	Escherichia coli O104:H4	serotype	Decreases
0	1	Escherichia coli O111:H-	serotype	Decreases
0	1	Escherichia coli O111:H11	serotype	Decreases
0	1	Escherichia coli O111:H8	serotype	Decreases
0	1	Escherichia coli O111:NM	serotype	Decreases
0	1	Escherichia coli O112ab:H8	serotype	Decreases
0	1	Escherichia coli O112ac:H19	serotype	Decreases
0	1	Escherichia coli O113:H21	serotype	Decreases
0	1	Escherichia coli O114:H49	serotype	Decreases
0	1	Escherichia coli O118:H16	serotype	Decreases
0	1	Escherichia coli O121:H19	serotype	Decreases
0	1	Escherichia coli O121:H7	serotype	Decreases
0	1	Escherichia coli O123:H11	serotype	Decreases
0	1	Escherichia coli O125ac:K+:H10	serotype	Decreases
0	1	Escherichia coli O126:H45	serotype	Decreases
0	1	Escherichia coli O127:H27	serotype	Decreases
0	1	Escherichia coli O127:H6	serotype	Decreases
0	1	Escherichia coli O128:H2	serotype	Decreases
0	1	Escherichia coli O128ac:H12	serotype	Decreases
0	1	Escherichia coli O139:H28	serotype	Decreases
0	1	Escherichia coli O145:H25	serotype	Decreases
0	1	Escherichia coli O145:H28	serotype	Decreases
0	1	Escherichia coli O145:NM	serotype	Decreases
0	1	Escherichia coli O146:H21	serotype	Decreases
0	1	Escherichia coli O15:H18	serotype	Decreases
0	1	Escherichia coli O150:H6	serotype	Decreases
0	1	Escherichia coli O152:H23	serotype	Decreases
0	1	Escherichia coli O153:H2	serotype	Decreases
0	1	Escherichia coli O156:H25	serotype	Decreases
0	1	Escherichia coli O157:H-	serotype	Decreases
0	1	Escherichia coli O157:H43	serotype	Decreases
0	1	Escherichia coli O157:H7	serotype	Decreases
0	1	Escherichia coli O157:NM	serotype	Decreases
0	1	Escherichia coli O16:H6	serotype	Decreases
0	1	Escherichia coli O165:H25	serotype	Decreases
0	1	Escherichia coli O167:H26	serotype	Decreases
0	1	Escherichia coli O174:H2	serotype	Decreases
0	1	Escherichia coli O174:H21	serotype	Decreases
0	1	Escherichia coli O174:H8	serotype	Decreases
0	1	Escherichia coli O176:H45	serotype	Decreases
0	1	Escherichia coli O177:NM	serotype	Decreases
0	1	Escherichia coli O2:H6	serotype	Decreases
0	1	Escherichia coli O2:K2:H1	serotype	Decreases
0	1	Escherichia coli O25:H1	serotype	Decreases
0	1	Escherichia coli O25:NM	serotype	Decreases
0	1	Escherichia coli O26:H1	serotype	Decreases
0	1	Escherichia coli O26:H11	serotype	Decreases
0	1	Escherichia coli O28ac:NM	serotype	Decreases
0	1	Escherichia coli O29:H4	serotype	Decreases
0	1	Escherichia coli O32:H37	serotype	Decreases
0	1	Escherichia coli O39:NM	serotype	Decreases
0	1	Escherichia coli O44:H18	serotype	Decreases
0	1	Escherichia coli O45:H2	serotype	Decreases
0	1	Escherichia coli O6:H16	serotype	Decreases
0	1	Escherichia coli O6:H16:CFA/II	serotype	Decreases
0	1	Escherichia coli O6:K2:H1	serotype	Decreases
0	1	Escherichia coli O69:H11	serotype	Decreases
0	1	Escherichia coli O7:H4	serotype	Decreases
0	1	Escherichia coli O7:K1	serotype	Decreases
0	1	Escherichia coli O78:H12	serotype	Decreases
0	1	Escherichia coli O78:H4	serotype	Decreases
0	1	Escherichia coli O79:H7	serotype	Decreases
0	1	Escherichia coli O8:H8	serotype	Decreases
0	1	Escherichia coli O81:NM	serotype	Decreases
0	1	Escherichia coli O83:H1	serotype	Decreases
0	1	Escherichia coli O86:H34	serotype	Decreases
0	1	Escherichia coli O89m:H10	serotype	Decreases
0	1	Escherichia coli O89m:H9	serotype	Decreases
0	1	Escherichia coli O9:H10	serotype	Decreases
0	1	Escherichia coli O91:H14	serotype	Decreases
0	1	Escherichia coli O91:NM	serotype	Decreases
0	1	Escherichia coli O99:H6	serotype	Decreases
0	1	Escherichia coli ONT:H33	serotype	Decreases
1	0	Agathobacter rectalis	species	Decreases
1	0	Lacticaseibacillus paracasei	species	Decreases
1	0	Segatella copri	species	Decreases
1	0	Escherichia coli	species	Decreases
1	0	Staphylococcus aureus	species	Decreases
1	0	Collinsella aerofaciens	species	Decreases
1	0	Clostridioides difficile	species	Decreases
1	0	Akkermansia muciniphila	species	Decreases
1	0	Mediterraneibacter gnavus	species	Decreases
0	1	Shigella dysenteriae	species	Decreases
0	1	Shigella flexneri	species	Decreases
0	1	Escherichia albertii	species	Decreases
0	1	Segatella bryantii	species	Decreases
1	0	Lachnospira eligens	species	Decreases
0	1	Escherichia fergusonii	species	Decreases
0	1	Leyella stercorea	species	Decreases
0	1	Shigella boydii	species	Decreases
0	1	Parolsenella catena	species	Decreases
0	1	Prevotella intermedia	species	Decreases
0	1	Shigella sonnei	species	Decreases
1	0	Coprococcus comes	species	Decreases
0	1	Leyella lascolaii	species	Decreases
1	0	Blautia obeum	species	Decreases
0	1	Escherichia marmotae	species	Decreases
1	0	Roseburia intestinalis	species	Decreases
0	1	Escherichia sp. E4742	species	Decreases
0	1	Paraprevotella clara	species	Decreases
0	1	Prevotella bivia	species	Decreases
0	1	Prevotella dentalis	species	Decreases
1	0	Eggerthella lenta	species	Decreases
1	0	Thomasclavelia ramosa	species	Decreases
1	0	Bacteroides fragilis	species	Decreases
0	1	Akkermansia glycaniphila	species	Decreases
0	1	Akkermansia massiliensis	species	Decreases
0	1	Candidatus Akkermansia intestinavium	species	Decreases
1	0	Bifidobacterium longum	species	Decreases
1	0	Lacrimispora saccharolytica	species	Decreases
0	1	Cryptococcus neoformans species complex	species group	Decreases
0	1	Lacticaseibacillus paracasei subsp. paracasei	subspecies	Decreases
0	1	Lacticaseibacillus paracasei subsp. tolerans	subspecies	Decreases
0	1	Bifidobacterium longum subsp. infantis	subspecies	Decreases
0	1	Bifidobacterium longum subsp. longum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suillum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suis	subspecies	Decreases

Impact of paroxetine hydrochloride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition	Positive Impact	Negative Impact	Benefit Ratio Impact
Acne	0.5	0	0
ADHD	1.1	0.1	10
Age-Related Macular Degeneration and Glaucoma	0.1		0.1
Allergic Rhinitis (Hay Fever)	1.4	0.7	1
Allergies	2.8	1.6	0.75
Allergy to milk products	1.3	0.3	3.33
Alopecia (Hair Loss)	0.2		0.2
Alzheimer's disease	1.4	2	-0.43
Amyotrophic lateral sclerosis (ALS) Motor Neuron	1.8	0.8	1.25
Ankylosing spondylitis	2.6	0.4	5.5
Anorexia Nervosa	0.1	0.8	-7
Antiphospholipid syndrome (APS)	0.9		0.9
Asthma	1.8	1.1	0.64
Atherosclerosis	0.9	0.3	2
Atrial fibrillation	1.3	1.7	-0.31
Autism	2.9	3.3	-0.14
Autoimmune Disease	0.4	0.1	3
benign prostatic hyperplasia	0.7	0	0
Biofilm	1.6		1.6
Bipolar Disorder	0.5	0.2	1.5
Brain Trauma	0.7	0.4	0.75
Breast Cancer	0.5		0.5
Cancer (General)		0.9	-0.9
Carcinoma	0.6	0.3	1
Celiac Disease	1	0.4	1.5
Cerebral Palsy	0.2	0.1	1
Chronic Fatigue Syndrome	1.4	1	0.4
Chronic Kidney Disease	1.3	1.2	0.08
Chronic Lyme	0.3	0.1	2
Chronic Obstructive Pulmonary Disease (COPD)	1.1	0.2	4.5
Chronic Urticaria (Hives)	0.8	1	-0.25
Coagulation / Micro clot triggering bacteria	1.4	0.1	13
Cognitive Function	0.2	0.1	1
Colorectal Cancer	1.9	1.3	0.46
Constipation	0.6	0.1	5
Coronary artery disease	2.1	0.9	1.33
COVID-19	2.9	3.4	-0.17
Crohn's Disease	2.5	1.9	0.32
Cushing's Syndrome (hypercortisolism)	0.5	0	0
cystic fibrosis	1.3	0.2	5.5
d-lactic acidosis (one form of brain fog)	1		1
deep vein thrombosis	1.7	0.1	16
Denture Wearers Oral Shifts	0.5		0.5
Depression	2.5	3.8	-0.52
Dermatomyositis	0.5	0	0
Eczema	1.5	0.1	14
Endometriosis	1.7	0.7	1.43
Epilepsy	1.4	0.6	1.33
erectile dysfunction	0.4	0	0
Fibromyalgia	0.7	0.8	-0.14
Functional constipation / chronic idiopathic constipation	1.9	1.1	0.73
gallstone disease (gsd)	1.2	0.2	5
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	0.1	0.2	-1
Generalized anxiety disorder	1.6	0.3	4.33
Gout	0.7	0.4	0.75
Graves' disease	0.2	0.3	-0.5
Gulf War Syndrome	0.1	0.6	-5
Halitosis	0		0
Hashimoto's thyroiditis	0.4	0.3	0.33
Heart Failure	2.4	0.9	1.67
Hidradenitis Suppurativa	0.9		0.9
High Histamine/low DAO	0.8	0	0
hypercholesterolemia (High Cholesterol)	0.5	0.3	0.67
hyperglycemia	1.2	0.6	1
Hyperlipidemia (High Blood Fats)	0.4	0.2	1
hypersomnia		0.2	-0.2
hypertension (High Blood Pressure	1.5	1	0.5
Hypothyroidism	1.3	0.2	5.5
Hypoxia	0.2		0.2
IgA nephropathy (IgAN)	0.6	1.3	-1.17
Inflammatory Bowel Disease	2.8	3.7	-0.32
Insomnia	0.9	1.2	-0.33
Intelligence	0.6	0.6	0
Intracranial aneurysms	0.2	0.2	0
Irritable Bowel Syndrome	2.5	1.1	1.27
ischemic stroke	0.7	1	-0.43
Liver Cirrhosis	2.5	1.5	0.67
Long COVID	1.8	1.9	-0.06
Low bone mineral density		0.2	-0.2
Lung Cancer	0.4	0.4	0
Lymphoma	0.4		0.4
Mast Cell Issues / mastitis	1.2	0.1	11
ME/CFS with IBS		0.3	-0.3
ME/CFS without IBS	0.4	0.1	3
Menopause	0	0.2	0
Metabolic Syndrome	2.5	1.1	1.27
Mood Disorders	2.3	3.7	-0.61
multiple chemical sensitivity [MCS]	0.2	0.1	1
Multiple Sclerosis	2.5	1.7	0.47
Multiple system atrophy (MSA)	0.5	0.1	4
myasthenia gravis	0.4	0.1	3
neuropathic pain	0	0.4	0
Neuropathy (all types)	0.3	0.3	0
neuropsychiatric disorders (PANDAS, PANS)	0.5		0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	2	1.6	0.25
NonCeliac Gluten Sensitivity	0.6	0.1	5
Obesity	3.5	2.5	0.4
obsessive-compulsive disorder	1.6	1.9	-0.19
Osteoarthritis	1.2	0.2	5
Osteoporosis	1	0.4	1.5
pancreatic cancer	0.3		0.3
Parkinson's Disease	3.1	2.6	0.19
Polycystic ovary syndrome	1.1	0.3	2.67
Postural orthostatic tachycardia syndrome		0.1	-0.1
Premenstrual dysphoric disorder	0.3		0.3
primary biliary cholangitis		0.2	-0.2
Primary sclerosing cholangitis	0	0.6	0
Psoriasis	1.9	1.7	0.12
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	3.2	1.1	1.91
Rosacea	0.3	0.1	2
Schizophrenia	1.1	0.5	1.2
scoliosis	1.1	0.2	4.5
sensorineural hearing loss	0.5		0.5
Sjögren syndrome	1.1	0.6	0.83
Sleep Apnea	0.3	0.2	0.5
Slow gastric motility / Gastroparesis	0.5	0	0
Small Intestinal Bacterial Overgrowth (SIBO)	0.8	0	0
Stress / posttraumatic stress disorder	1.2	0.7	0.71
Systemic Lupus Erythematosus	2	0.3	5.67
Tic Disorder		1	-1
Tourette syndrome	0.2	0	0
Type 1 Diabetes	1.4	0.5	1.8
Type 2 Diabetes	3	1.9	0.58
Ulcerative colitis	1.9	1.6	0.19
Unhealthy Ageing	0.8	0.9	-0.13
Vitiligo	0.2	0.3	-0.5

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