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🍽️ (s)-(-)-atenolol,(prescription)

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  1. Beta-Blocker Action: Atenolol is a selective beta-1 adrenergic receptor antagonist, meaning it specifically blocks the action of beta-1 adrenergic receptors. By inhibiting these receptors, atenolol reduces the effects of adrenaline and noradrenaline on the heart, leading to decreased heart rate and reduced force of contraction of the heart muscle.

  2. Antihypertensive Effects: (S)-(-)-atenolol is primarily used in the treatment of hypertension (high blood pressure). By decreasing heart rate and cardiac output, as well as reducing renin release from the kidneys, atenolol helps lower blood pressure and reduce the workload on the heart. This can help prevent complications associated with hypertension, such as stroke, heart attack, and kidney damage.

  3. Management of Angina Pectoris: Atenolol may also be prescribed for the management of angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By decreasing heart rate and myocardial oxygen demand, atenolol helps relieve anginal symptoms and improve exercise tolerance in individuals with stable angina.

  4. Antiarrhythmic Effects: Atenolol has antiarrhythmic properties and may be used in the treatment of certain types of cardiac arrhythmias, particularly supraventricular arrhythmias such as atrial fibrillation or atrial flutter. By slowing conduction through the atrioventricular node and suppressing abnormal electrical activity in the heart, atenolol can help restore normal heart rhythm and prevent arrhythmic events.

  5. Reduction of Myocardial Oxygen Demand: By reducing heart rate and myocardial contractility, (S)-(-)-atenolol decreases myocardial oxygen demand, which can be beneficial in individuals with coronary artery disease or ischemic heart disease. Lowering myocardial oxygen demand helps improve oxygen supply-demand balance in the heart and may reduce the frequency and severity of anginal episodes.

  6. Dosage and Administration: (S)-(-)-atenolol is typically administered orally in the form of tablets or capsules. The dosage and frequency of administration may vary depending on the patient's age, weight, medical condition, and response to treatment. It is usually taken once daily, with or without food.

  7. Side Effects: Common side effects of (S)-(-)-atenolol may include fatigue, dizziness, lightheadedness, bradycardia (slow heart rate), hypotension (low blood pressure), cold extremities, gastrointestinal disturbances (e.g., nausea, diarrhea), and worsening of heart failure symptoms in susceptible individuals. These side effects are usually mild and transient but should be reported to a healthcare provider if they persist or worsen over time.

  8. Contraindications: (S)-(-)-atenolol is contraindicated in individuals with known hypersensitivity to beta-blockers, severe bradycardia, heart block greater than first degree, cardiogenic shock, decompensated heart failure, and certain other cardiac conditions. It should be used with caution in patients with asthma, chronic obstructive pulmonary disease (COPD), diabetes, peripheral vascular disease, and other comorbidities.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of (s)-(-)-atenolol,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by (s)-(-)-atenolol,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Eggerthella genus Decreases
0 1 Streptococcus genus Decreases
0 1 Dorea genus Decreases
0 1 Collinsella genus Decreases
0 1 Bilophila genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Escherichia genus Decreases
0 1 Veillonella genus Decreases
0 1 Enterocloster genus Decreases
0 1 Parolsenella genus Decreases
0 1 Shigella genus Decreases
0 1 Bacteroides genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Clostridium genus Decreases
0 1 Coprococcus genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Agathobacter genus Decreases
0 1 Clostridioides genus Decreases
0 1 Lacticaseibacillus genus Decreases
1 0 Akkermansia genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Eggerthella lenta species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Collinsella aerofaciens species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Escherichia coli species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Veillonella parvula species Decreases
1 0 Enterocloster bolteae species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Streptococcus lactarius species Decreases
1 0 Parabacteroides merdae species Decreases
0 1 Streptococcus salivarius species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Streptococcus australis species Decreases
1 0 Bacteroides caccae species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Streptococcus gordonii species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Parolsenella catena species Decreases
0 1 Shigella flexneri species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Escherichia albertii species Decreases
1 0 Coprococcus comes species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Dorea longicatena species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Veillonella rodentium species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Blautia obeum species Decreases
0 1 Coprococcus catus species Decreases
0 1 Shigella boydii species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Streptococcus sp. A12 species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Actinomyces oris species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Wansuia hejianensis species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bacteroides ovatus species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of (s)-(-)-atenolol,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2
Acne 0.1 -0.1
ADHD 1.1 0.5 1.2
Age-Related Macular Degeneration and Glaucoma 0.4 0.1 3
Allergic Rhinitis (Hay Fever) 1.2 1.7 -0.42
Allergies 3.1 1.1 1.82
Allergy to milk products 1 0.5 1
Alopecia (Hair Loss) 0.6 0.6
Alzheimer's disease 1.9 2.1 -0.11
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.7 0.5 0.4
Ankylosing spondylitis 1.8 0.3 5
Anorexia Nervosa 0.8 0.7 0.14
Antiphospholipid syndrome (APS) 0.7 0.2 2.5
Asthma 2.2 0.9 1.44
Atherosclerosis 1.1 0.1 10
Atrial fibrillation 1.3 0.8 0.63
Autism 3.6 2.6 0.38
Autoimmune Disease 0.7 0.2 2.5
Barrett esophagus cancer 0.2 0.4 -1
benign prostatic hyperplasia 0.3 0.1 2
Biofilm 1.6 1.6
Bipolar Disorder 1.3 0.7 0.86
Brain Trauma 0.7 0.3 1.33
Breast Cancer 0.4 0.4
Cancer (General) 0.2 0.7 -2.5
Carcinoma 2.2 1 1.2
Celiac Disease 0.9 1.1 -0.22
Cerebral Palsy 0.7 0.3 1.33
Chronic Fatigue Syndrome 2.8 3.1 -0.11
Chronic Kidney Disease 2 0.7 1.86
Chronic Lyme 0 0.1 0
Chronic Obstructive Pulmonary Disease (COPD) 1.8 0.6 2
Chronic Urticaria (Hives) 1 0 0
Coagulation / Micro clot triggering bacteria 1 0.5 1
Cognitive Function 1.4 0.5 1.8
Colorectal Cancer 2.5 1 1.5
Constipation 0.5 0.5
Coronary artery disease 1.5 0.4 2.75
COVID-19 4.9 4.2 0.17
Crohn's Disease 3.1 1.3 1.38
Cushing's Syndrome (hypercortisolism) 0.1 -0.1
cystic fibrosis 0.5 0.4 0.25
d-lactic acidosis (one form of brain fog) 0.3 0.3
deep vein thrombosis 0.7 0.6 0.17
Denture Wearers Oral Shifts 1 1
Depression 4.8 3.1 0.55
Dermatomyositis 0.4 0.1 3
Eczema 0.9 0.9 0
Endometriosis 1.6 0.7 1.29
Eosinophilic Esophagitis 0 0.5 0
Epilepsy 1.6 0.5 2.2
erectile dysfunction 0.5 0.1 4
Fibromyalgia 1.3 0.4 2.25
Functional constipation / chronic idiopathic constipation 1.6 0.9 0.78
gallstone disease (gsd) 1.2 0.1 11
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.2 0.6 -2
Generalized anxiety disorder 1.5 0.8 0.88
giant cell arteritis 0.1 -0.1
Glioblastoma 0.4 -0.4
Gout 1.2 0.3 3
Graves' disease 0.8 1.4 -0.75
Gulf War Syndrome 0.5 0.1 4
Halitosis 0.7 0.4 0.75
Hashimoto's thyroiditis 1 0.5 1
Heart Failure 1.6 0.4 3
hemorrhagic stroke 0.4 0.4
Hidradenitis Suppurativa 0.7 0.1 6
High Histamine/low DAO 0.5 0.2 1.5
hypercholesterolemia (High Cholesterol) 0.4 0 0
hyperglycemia 1.2 0.3 3
Hyperlipidemia (High Blood Fats) 0.6 0.3 1
hypersomnia 0.5 -0.5
hypertension (High Blood Pressure 2 1.3 0.54
Hypothyroidism 0 0.5 0
Hypoxia 0.8 0.8
IgA nephropathy (IgAN) 1.2 0.5 1.4
Inflammatory Bowel Disease 3.5 3.5 0
Insomnia 1.2 0.8 0.5
Intelligence 0.6 0.6
Intracranial aneurysms 0.4 0.4 0
Irritable Bowel Syndrome 3 1.4 1.14
ischemic stroke 1.3 0.4 2.25
Liver Cirrhosis 2.9 1.9 0.53
Long COVID 2.4 2.9 -0.21
Low bone mineral density 0.2 -0.2
Lung Cancer 0.6 0.6 0
Lymphoma 0.3 0.3
Mast Cell Issues / mastitis 0.7 0.3 1.33
ME/CFS with IBS 0.7 1.4 -1
ME/CFS without IBS 1.5 1.2 0.25
membranous nephropathy 0.4 0.4
Menopause 0.7 0 0
Metabolic Syndrome 3.9 2.1 0.86
Mood Disorders 4.7 3.1 0.52
multiple chemical sensitivity [MCS] 0.7 0.7
Multiple Sclerosis 4.1 1.7 1.41
Multiple system atrophy (MSA) 0.6 0.2 2
myasthenia gravis 0.6 0.1 5
neuropathic pain 0.4 0.2 1
Neuropathy (all types) 0.7 0.3 1.33
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.1 0.9 1.33
NonCeliac Gluten Sensitivity 0.8 0.2 3
Obesity 3.9 2.7 0.44
obsessive-compulsive disorder 1.9 1.1 0.73
Osteoarthritis 0.9 0.7 0.29
Osteoporosis 1.1 0.8 0.38
pancreatic cancer 0.4 0.4 0
Parkinson's Disease 3.9 1.8 1.17
Polycystic ovary syndrome 1.9 1.4 0.36
Postural orthostatic tachycardia syndrome 0.1 0.2 -1
Premenstrual dysphoric disorder 0.4 0.1 3
primary biliary cholangitis 0.8 0.8 0
Primary sclerosing cholangitis 1.6 0.6 1.67
Psoriasis 2.3 0.3 6.67
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.1 1.1 2.73
Rosacea 0.4 0.1 3
Schizophrenia 2.9 0.7 3.14
scoliosis 0.5 0.4 0.25
sensorineural hearing loss 0.1 0.1
Sjögren syndrome 1.1 0.8 0.38
Sleep Apnea 0.8 0.5 0.6
Slow gastric motility / Gastroparesis 0.7 0.1 6
Small Intestinal Bacterial Overgrowth (SIBO) 1.1 0.1 10
Stress / posttraumatic stress disorder 1.1 1.2 -0.09
Systemic Lupus Erythematosus 1.7 0.3 4.67
Tic Disorder 0.5 0.7 -0.4
Tourette syndrome 0.7 0.1 6
Type 1 Diabetes 1.4 1.2 0.17
Type 2 Diabetes 3.7 2 0.85
Ulcerative colitis 2.1 1.1 0.91
Unhealthy Ageing 2 0.3 5.67
Vitiligo 0.8 0.4 1

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