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Muscle Wasting: Nandrolone is often prescribed to treat muscle wasting conditions such as cachexia (wasting syndrome) associated with chronic illnesses like HIV/AIDS, cancer, or other diseases. It helps promote muscle growth and weight gain, improving overall muscle mass and strength.
Anemia: Nandrolone can stimulate the production of red blood cells, which may be beneficial in the treatment of anemia, particularly in individuals with conditions such as chronic kidney disease, aplastic anemia, or myelofibrosis. By increasing red blood cell production, nandrolone can improve oxygen transport in the body and alleviate symptoms of anemia such as fatigue and weakness.
Hormone Imbalances: In some cases, nandrolone may be used to address hormone imbalances, particularly in men with conditions such as hypogonadism (low testosterone levels). It can help restore testosterone levels to within the normal range, improving symptoms such as low libido, fatigue, and reduced muscle mass.
Osteoporosis: While not a primary indication, nandrolone has been studied for its potential role in the treatment of osteoporosis, a condition characterized by weakened bones and increased risk of fractures. Some research suggests that nandrolone may have beneficial effects on bone density and strength, potentially reducing the risk of fractures in individuals with osteoporosis.
Recovery from Surgery or Injury: Nandrolone may be used to promote recovery from surgery, trauma, or severe injury by enhancing protein synthesis, reducing muscle breakdown, and improving overall recovery time. However, its use for this purpose is controversial and not widely recommended due to potential side effects and risks associated with long-term steroid use.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Reduces |
| species | Akkermansia muciniphila | Reduces |
| species | Bifidobacterium longum | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 0 | 1 | Akkermansiaceae | family | Decreases |
| 0 | 1 | Dorea | genus | Decreases |
| 0 | 1 | Ruminococcus | genus | Decreases |
| 0 | 1 | Bacteroides | genus | Decreases |
| 0 | 1 | Bifidobacterium | genus | Decreases |
| 0 | 1 | Bilophila | genus | Decreases |
| 0 | 1 | Coprococcus | genus | Decreases |
| 0 | 1 | Fusobacterium | genus | Decreases |
| 0 | 1 | Lachnospira | genus | Decreases |
| 0 | 1 | Mediterraneibacter | genus | Decreases |
| 0 | 1 | Odoribacter | genus | Decreases |
| 0 | 1 | Enterocloster | genus | Decreases |
| 0 | 1 | Thomasclavelia | genus | Decreases |
| 1 | 0 | Akkermansia | genus | Decreases |
| 0 | 1 | Lacticaseibacillus | genus | Decreases |
| 0 | 1 | environmental samples | no rank | Decreases |
| 0 | 1 | unclassified Akkermansia | no rank | Decreases |
| 1 | 0 | Bacteroides xylanisolvens | species | Decreases |
| 1 | 0 | Thomasclavelia ramosa | species | Decreases |
| 1 | 0 | Bacteroides thetaiotaomicron | species | Decreases |
| 1 | 0 | Bilophila wadsworthia | species | Decreases |
| 1 | 0 | [Ruminococcus] torques | species | Decreases |
| 1 | 0 | Enterocloster bolteae | species | Decreases |
| 0 | 1 | Akkermansia massiliensis | species | Decreases |
| 0 | 1 | Candidatus Akkermansia intestinavium | species | Decreases |
| 1 | 0 | Odoribacter splanchnicus | species | Decreases |
| 1 | 0 | Bifidobacterium longum | species | Decreases |
| 1 | 0 | Dorea formicigenerans | species | Decreases |
| 1 | 0 | Coprococcus comes | species | Decreases |
| 1 | 0 | Lacticaseibacillus paracasei | species | Decreases |
| 1 | 0 | Ruminococcus bromii | species | Decreases |
| 1 | 0 | Akkermansia muciniphila | species | Decreases |
| 1 | 0 | Bacteroides ovatus | species | Decreases |
| 1 | 0 | Fusobacterium nucleatum | species | Decreases |
| 0 | 1 | Akkermansia glycaniphila | species | Decreases |
| 1 | 0 | Lachnospira eligens | species | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. longum | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. infantis | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. suis | subspecies | Decreases |
| 0 | 1 | Lacticaseibacillus paracasei subsp. paracasei | subspecies | Decreases |
| 0 | 1 | Fusobacterium nucleatum subsp. nucleatum | subspecies | Decreases |
| 0 | 1 | Lacticaseibacillus paracasei subsp. tolerans | subspecies | Decreases |
| 0 | 1 | Bifidobacterium longum subsp. suillum | subspecies | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.7 | 0.7 | |
| Acne | 0.6 | 0.7 | -0.17 |
| ADHD | 1.4 | 0.6 | 1.33 |
| Age-Related Macular Degeneration and Glaucoma | 0.6 | 0.6 | |
| Allergic Rhinitis (Hay Fever) | 1.2 | 0.5 | 1.4 |
| Allergies | 1.5 | 2 | -0.33 |
| Allergy to milk products | 0.9 | 0.6 | 0.5 |
| Alopecia (Hair Loss) | 0.6 | 0.6 | |
| Alzheimer's disease | 2.5 | 2.6 | -0.04 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 1.8 | 0.4 | 3.5 |
| Ankylosing spondylitis | 1.5 | 1.2 | 0.25 |
| Anorexia Nervosa | 0.6 | 1.2 | -1 |
| Antiphospholipid syndrome (APS) | 0.4 | 0.3 | 0.33 |
| Asthma | 2.2 | 0.7 | 2.14 |
| Atherosclerosis | 1.2 | 0.5 | 1.4 |
| Atrial fibrillation | 2 | 0.9 | 1.22 |
| Autism | 3.1 | 3.1 | 0 |
| Autoimmune Disease | 0.3 | 0.3 | 0 |
| Barrett esophagus cancer | 0.3 | 0.3 | |
| benign prostatic hyperplasia | 0.3 | -0.3 | |
| Biofilm | 0 | 0 | |
| Bipolar Disorder | 0.9 | 0.6 | 0.5 |
| Brain Trauma | 0.3 | 0.9 | -2 |
| Breast Cancer | 0.6 | 0.3 | 1 |
| Cancer (General) | 0.6 | 0.6 | 0 |
| Carcinoma | 2.3 | 1.7 | 0.35 |
| Celiac Disease | 0.6 | 2.5 | -3.17 |
| Cerebral Palsy | 0.6 | 0.6 | 0 |
| Chronic Fatigue Syndrome | 1.6 | 2.6 | -0.63 |
| Chronic Kidney Disease | 1.3 | 1.3 | 0 |
| Chronic Lyme | 0.3 | -0.3 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.6 | 0.9 | -0.5 |
| Chronic Urticaria (Hives) | 0.1 | -0.1 | |
| Coagulation / Micro clot triggering bacteria | 0.3 | -0.3 | |
| Cognitive Function | 1.5 | 0.6 | 1.5 |
| Colorectal Cancer | 2.9 | 0.9 | 2.22 |
| Constipation | 0.9 | 0.3 | 2 |
| Coronary artery disease | 0.3 | 0.9 | -2 |
| COVID-19 | 2.8 | 3.2 | -0.14 |
| Crohn's Disease | 2.7 | 2.7 | 0 |
| Cushing's Syndrome (hypercortisolism) | 0.3 | -0.3 | |
| cystic fibrosis | 0.6 | -0.6 | |
| deep vein thrombosis | 0.6 | 0.6 | 0 |
| Denture Wearers Oral Shifts | 0 | 0 | |
| Depression | 4.1 | 3.1 | 0.32 |
| Dermatomyositis | 0.3 | -0.3 | |
| Eczema | 0.3 | 0.9 | -2 |
| Endometriosis | 1.4 | 1.2 | 0.17 |
| Eosinophilic Esophagitis | 0.3 | 0.3 | |
| Epilepsy | 0.9 | 0.7 | 0.29 |
| erectile dysfunction | 1.1 | 0.3 | 2.67 |
| Fibromyalgia | 1.4 | 0.7 | 1 |
| Functional constipation / chronic idiopathic constipation | 1.9 | 1.6 | 0.19 |
| gallstone disease (gsd) | 0.9 | 0.6 | 0.5 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.3 | 0.3 | 0 |
| Generalized anxiety disorder | 0.9 | 1 | -0.11 |
| Gout | 1.8 | 0.9 | 1 |
| Graves' disease | 0.9 | 1.7 | -0.89 |
| Gulf War Syndrome | 0.3 | 0.8 | -1.67 |
| Halitosis | 0.6 | 0.6 | |
| Hashimoto's thyroiditis | 2.2 | 1.6 | 0.38 |
| Heart Failure | 0.9 | 0.6 | 0.5 |
| hemorrhagic stroke | 0.9 | 0.9 | |
| Hidradenitis Suppurativa | 1.2 | 1.2 | |
| High Histamine/low DAO | 0.6 | -0.6 | |
| hypercholesterolemia (High Cholesterol) | 0.3 | 0.1 | 2 |
| hyperglycemia | 0.6 | 0.7 | -0.17 |
| Hyperlipidemia (High Blood Fats) | 0.6 | 0.6 | |
| hypersomnia | 0.3 | -0.3 | |
| hypertension (High Blood Pressure | 2.2 | 2.4 | -0.09 |
| Hypothyroidism | 0 | 0.6 | 0 |
| Hypoxia | 1.2 | 0.3 | 3 |
| IgA nephropathy (IgAN) | 0.9 | 0.8 | 0.13 |
| Inflammatory Bowel Disease | 1.9 | 2.7 | -0.42 |
| Insomnia | 1.5 | 1 | 0.5 |
| Intelligence | 0.6 | 0.6 | |
| Intracranial aneurysms | 0.9 | 0.6 | 0.5 |
| Irritable Bowel Syndrome | 2.4 | 1.6 | 0.5 |
| ischemic stroke | 1.1 | 0.3 | 2.67 |
| Liver Cirrhosis | 2.6 | 3 | -0.15 |
| Long COVID | 2.8 | 3.6 | -0.29 |
| Low bone mineral density | 0.6 | -0.6 | |
| Lung Cancer | 0.3 | 0.9 | -2 |
| Lymphoma | 0.3 | 0.3 | |
| Mast Cell Issues / mastitis | 0 | 0.9 | 0 |
| ME/CFS with IBS | 0.3 | 0.8 | -1.67 |
| ME/CFS without IBS | 1.3 | -1.3 | |
| Menopause | 0.2 | 0 | 0 |
| Metabolic Syndrome | 3.1 | 3.2 | -0.03 |
| Mood Disorders | 3.5 | 1.9 | 0.84 |
| multiple chemical sensitivity [MCS] | 0 | 0 | |
| Multiple Sclerosis | 2 | 1.3 | 0.54 |
| Multiple system atrophy (MSA) | 0.1 | 0.6 | -5 |
| neuropathic pain | 1.1 | -1.1 | |
| Neuropathy (all types) | 0 | 0.2 | 0 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.3 | 0.3 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 2.6 | 2 | 0.3 |
| NonCeliac Gluten Sensitivity | 0.6 | 0.6 | 0 |
| Obesity | 4.7 | 3.9 | 0.21 |
| obsessive-compulsive disorder | 0.7 | 2.2 | -2.14 |
| Osteoarthritis | 0.8 | 0.9 | -0.13 |
| Osteoporosis | 0.6 | 1.2 | -1 |
| pancreatic cancer | 0.6 | 0.3 | 1 |
| Parkinson's Disease | 2.7 | 2.9 | -0.07 |
| Polycystic ovary syndrome | 1.5 | 1.5 | 0 |
| Postural orthostatic tachycardia syndrome | 0.6 | -0.6 | |
| Premenstrual dysphoric disorder | 0.3 | 0.3 | |
| primary biliary cholangitis | 0.6 | 0.3 | 1 |
| Primary sclerosing cholangitis | 0.6 | 0.6 | 0 |
| Psoriasis | 0.8 | 0.6 | 0.33 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 2.7 | 2 | 0.35 |
| Rosacea | 1 | 0.3 | 2.33 |
| Schizophrenia | 2.5 | 1.5 | 0.67 |
| scoliosis | 0.3 | 0.6 | -1 |
| Sjögren syndrome | 0.3 | 1.2 | -3 |
| Sleep Apnea | 2 | 0.9 | 1.22 |
| Slow gastric motility / Gastroparesis | 0.6 | 0.3 | 1 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.9 | 0.1 | 8 |
| Stress / posttraumatic stress disorder | 1.5 | 0.9 | 0.67 |
| Systemic Lupus Erythematosus | 1.4 | 1.2 | 0.17 |
| Tic Disorder | 0.6 | 0.9 | -0.5 |
| Tourette syndrome | 0.6 | 0.3 | 1 |
| Type 1 Diabetes | 1.8 | 1.7 | 0.06 |
| Type 2 Diabetes | 2.9 | 2.9 | 0 |
| Ulcerative colitis | 2 | 2.3 | -0.15 |
| Unhealthy Ageing | 2.5 | 0.9 | 1.78 |
| Vitiligo | 1.2 | 0.4 | 2 |
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