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🍽️ 4-hydroxyphenyl-beta-D-glucopyranoside {Arbutin}

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  1. Skin Lightening: Arbutin is well-known for its skin-lightening properties. It works by inhibiting tyrosinase, an enzyme involved in the production of melanin, the pigment responsible for skin color. By inhibiting tyrosinase activity, arbutin can help to reduce the production of melanin in the skin, leading to a lighter complexion and fading of hyperpigmentation, such as age spots, sun spots, and melasma.

  2. Anti-inflammatory: Arbutin has been reported to possess anti-inflammatory properties, which may be beneficial for various skin conditions characterized by inflammation, such as acne, eczema, and rosacea. By reducing inflammation, arbutin may help to alleviate redness, swelling, and irritation associated with these skin conditions.

  3. Antioxidant: Arbutin exhibits antioxidant activity, meaning it can neutralize harmful free radicals in the body. Free radicals are unstable molecules that can damage cells and contribute to aging and various diseases. By scavenging free radicals, arbutin may help to protect cells from oxidative stress and reduce the risk of oxidative damage to the skin and other tissues.

  4. Hyperpigmentation Disorders: Arbutin has been studied for its potential therapeutic use in the treatment of hyperpigmentation disorders, such as melasma, post-inflammatory hyperpigmentation, and age-related skin discolorations. Its ability to inhibit melanin production makes it a promising ingredient in skincare formulations designed to address these conditions.

  5. Sun Protection: Some research suggests that arbutin may have photoprotective properties, meaning it may help to protect the skin from the damaging effects of ultraviolet (UV) radiation from the sun. While arbutin itself is not a substitute for sunscreen, it may complement sun protection measures by reducing the risk of UV-induced skin damage and premature aging.

  6. Wound Healing: Arbutin has been investigated for its potential role in promoting wound healing and tissue repair. Its anti-inflammatory and antioxidant properties may help to reduce inflammation and oxidative stress at the site of injury, facilitating the healing process and minimizing scarring.

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Data Contradictions — Limits of Certainity

Impacted of 4-hydroxyphenyl-beta-D-glucopyranoside {Arbutin} On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Increases
species Bacillus velezensis Reduces
species Bifidobacterium adolescentis Increases
species Bifidobacterium animalis Reduces
species Bifidobacterium bifidum Increases
species Bifidobacterium breve Increases
species Bifidobacterium catenulatum Increases
species Bifidobacterium longum Reduces
species Bifidobacterium pseudocatenulatum Increases
species Bifidobacterium pseudolongum Increases
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
subspecies Bifidobacterium animalis subsp. lactis Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by 4-hydroxyphenyl-beta-D-glucopyranoside {Arbutin}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Betaproteobacteria class Decreases
1 0 Lachnospiraceae family Decreases
0 1 Desulfovibrionaceae family Decreases
0 1 Oscillospiraceae family Decreases
0 1 Alcaligenaceae family Decreases
0 1 Burkholderiaceae family Decreases
0 1 Comamonadaceae family Decreases
0 1 Oxalobacteraceae family Decreases
0 1 Sphaerotilaceae family Decreases
0 1 Sutterellaceae family Decreases
0 2 Eubacteriaceae family Increases
0 1 Bifidobacteriaceae family Increases
1 0 Desulfovibrio genus Decreases
1 0 Ruminiclostridium genus Decreases
0 2 Mediterraneibacter genus Decreases
0 1 Helicobacter genus Decreases
0 1 Streptococcus genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Acetatifactor genus Decreases
0 1 Acetitomaculum genus Decreases
0 1 Agathobacter genus Decreases
0 1 Anaerobium genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Anaerocolumna genus Decreases
0 1 Anaeromicropila genus Decreases
0 1 Anaeropeptidivorans genus Decreases
0 1 Anaerosacchariphilus genus Decreases
0 1 Anaerosporobacter genus Decreases
0 1 Anaerostipes genus Decreases
0 1 Anaerotaenia genus Decreases
0 1 Anaerotignum genus Decreases
0 1 Anthropogastromicrobium genus Decreases
0 1 Bariatricus genus Decreases
0 1 Blautia genus Decreases
0 1 Brotaphodocola genus Decreases
0 1 Butyribacter genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Candidatus Epulonipiscium genus Decreases
0 1 Catenibacillus genus Decreases
0 1 Catonella genus Decreases
0 1 Chordicoccus genus Decreases
0 1 Claveliimonas genus Decreases
0 1 Coprococcus genus Decreases
0 1 Cuneatibacter genus Decreases
0 1 Diplocloster genus Decreases
0 1 Dorea genus Decreases
0 1 Eisenbergiella genus Decreases
0 1 Enterocloster genus Decreases
0 1 Extibacter genus Decreases
0 1 Faecalicatena genus Decreases
0 1 Faecalimonas genus Decreases
0 1 Frisingicoccus genus Decreases
0 1 Fusicatenibacter genus Decreases
0 1 Gallintestinimicrobium genus Decreases
0 1 Gluceribacter genus Decreases
0 1 Herbinix genus Decreases
0 1 Hespellia genus Decreases
0 1 Hominifimenecus genus Decreases
0 1 Hominisplanchenecus genus Decreases
0 1 Hoministercoradaptatus genus Decreases
0 1 Hominiventricola genus Decreases
0 1 Jingyaoa genus Decreases
0 1 Johnsonella genus Decreases
0 1 Jutongia genus Decreases
0 1 Kineothrix genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Lachnobacterium genus Decreases
0 1 Lachnoclostridium genus Decreases
0 1 Lachnospira genus Decreases
0 1 Lachnotalea genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Lientehia genus Decreases
0 1 Luxibacter genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Merdimonas genus Decreases
0 1 Mobilitalea genus Decreases
0 1 Moryella genus Decreases
0 1 Muricomes genus Decreases
0 1 Murimonas genus Decreases
0 1 Niameybacter genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Oliverpabstia genus Decreases
0 1 Oribacterium genus Decreases
0 1 Parablautia genus Decreases
0 1 Pararoseburia genus Decreases
0 1 Parasporobacterium genus Decreases
0 1 Porcincola genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Qiania genus Decreases
0 1 Robinsoniella genus Decreases
0 1 Roseburia genus Decreases
0 1 Schaedlerella genus Decreases
0 1 Sellimonas genus Decreases
0 1 Shuttleworthella genus Decreases
0 1 Simiaoa genus Decreases
0 1 Sporobacterium genus Decreases
0 1 Sporofaciens genus Decreases
0 1 Stomatobaculum genus Decreases
0 1 Suonthocola genus Decreases
0 1 Syntrophococcus genus Decreases
0 1 Tyzzerella genus Decreases
0 1 Waltera genus Decreases
0 1 Wansuia genus Decreases
0 1 Wujia genus Decreases
0 1 Zhenhengia genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Escherichia genus Decreases
2 0 Eubacterium genus Increases
1 2 Bifidobacterium genus Increases
0 1 Lactobacillus genus Increases
0 1 Oscillospiraceae incertae sedis no rank Decreases
0 1 Burkholderiales genera incertae sedis no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 Lachnospiraceae incertae sedis no rank Decreases
0 1 unclassified Burkholderiales no rank Decreases
0 1 unclassified Desulfovibrio no rank Decreases
0 1 unclassified Lachnospiraceae no rank Decreases
0 1 unclassified Ruminiclostridium no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 2 environmental samples no rank Increases
0 2 unclassified Eubacterium (in: firmicutes) no rank Increases
0 1 environmental samples no rank Increases
0 1 unclassified Bifidobacterium no rank Increases
1 0 Burkholderiales order Decreases
0 1 Eubacteriales order Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 [Clostridium] leptum species Decreases
1 0 Bacillus velezensis species Decreases
1 0 Helicobacter ganmani species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 1 Bifidobacterium animalis species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Escherichia coli species Decreases
1 1 Bifidobacterium longum species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Candidatus Desulfovibrio faecigallinarum species Decreases
0 1 Candidatus Desulfovibrio trichonymphae species Decreases
0 1 Desulfovibrio aminophilus species Decreases
0 1 Desulfovibrio biadhensis species Decreases
0 1 Desulfovibrio caledoniensis species Decreases
0 1 Desulfovibrio cuneatus species Decreases
0 1 Desulfovibrio desulfuricans species Decreases
0 1 Desulfovibrio diazotrophicus species Decreases
0 1 Desulfovibrio fairfieldensis species Decreases
0 1 Desulfovibrio ferrophilus species Decreases
0 1 Desulfovibrio giganteus species Decreases
0 1 Desulfovibrio inopinatus species Decreases
0 1 Desulfovibrio intestinalis species Decreases
0 1 Desulfovibrio lacusfryxellense species Decreases
0 1 Desulfovibrio legallii species Decreases
0 1 Desulfovibrio litoralis species Decreases
0 1 Desulfovibrio longreachensis species Decreases
0 1 Desulfovibrio mangrovi species Decreases
0 1 Desulfovibrio oryzae species Decreases
0 1 Desulfovibrio oviles species Decreases
0 1 Desulfovibrio oxyclinae species Decreases
0 1 Desulfovibrio piger species Decreases
0 1 Desulfovibrio porci species Decreases
0 1 Desulfovibrio psychrotolerans species Decreases
0 1 Desulfovibrio simplex species Decreases
0 1 Desulfovibrio subterraneus species Decreases
0 1 Nitratidesulfovibrio vulgaris species Decreases
0 1 Ruminiclostridium cellobioparum species Decreases
0 1 Ruminiclostridium cellulolyticum species Decreases
0 1 Ruminiclostridium herbifermentans species Decreases
0 1 Ruminiclostridium hungatei species Decreases
0 1 Ruminiclostridium josui species Decreases
0 1 Ruminiclostridium papyrosolvens species Decreases
0 1 Ruminiclostridium sufflavum species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Streptococcus salivarius species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Streptococcus australis species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 2 [Eubacterium] cellulosolvens species Increases
0 2 Candidatus Eubacterium faecale species Increases
0 2 Candidatus Eubacterium faecavium species Increases
0 2 Candidatus Eubacterium faecipullorum species Increases
0 2 Eubacterium barkeri species Increases
0 2 Eubacterium callanderi species Increases
0 2 Eubacterium coprostanoligenes species Increases
0 2 Eubacterium limosum species Increases
0 2 Eubacterium maltosivorans species Increases
0 2 Eubacterium multiforme species Increases
0 2 Eubacterium oxidoreducens species Increases
0 2 Eubacterium plexicaudatum species Increases
0 2 Eubacterium pyruvativorans species Increases
0 2 Eubacterium ramulus species Increases
0 2 Eubacterium rangiferina species Increases
0 2 Eubacterium ruminantium species Increases
0 2 Eubacterium segne species Increases
0 2 Eubacterium uniforme species Increases
0 2 Eubacterium ventriosum species Increases
0 2 Eubacterium xylanophilum species Increases
0 1 Bifidobacterium actinocoloniiforme species Increases
0 1 Bifidobacterium adolescentis species Increases
0 1 Bifidobacterium aesculapii species Increases
0 1 Bifidobacterium angulatum species Increases
0 1 Bifidobacterium asteroides species Increases
0 1 Bifidobacterium avesanii species Increases
0 1 Bifidobacterium biavatii species Increases
0 1 Bifidobacterium bifidum species Increases
0 1 Bifidobacterium bohemicum species Increases
0 1 Bifidobacterium bombi species Increases
0 1 Bifidobacterium boum species Increases
0 1 Bifidobacterium breve species Increases
0 1 Bifidobacterium callitrichidarum species Increases
0 1 Bifidobacterium callitrichos species Increases
0 1 Bifidobacterium catenulatum species Increases
0 1 Bifidobacterium choerinum species Increases
0 1 Bifidobacterium commune species Increases
0 1 Bifidobacterium coryneforme species Increases
0 1 Bifidobacterium cuniculi species Increases
0 1 Bifidobacterium dentium species Increases
0 1 Bifidobacterium eulemuris species Increases
0 1 Bifidobacterium faecale species Increases
0 1 Bifidobacterium gallicum species Increases
0 1 Bifidobacterium imperatoris species Increases
0 1 Bifidobacterium indicum species Increases
0 1 Bifidobacterium lemurum species Increases
0 1 Bifidobacterium magnum species Increases
0 1 Bifidobacterium merycicum species Increases
0 1 Bifidobacterium minimum species Increases
0 1 Bifidobacterium mongoliense species Increases
0 1 Bifidobacterium moukalabense species Increases
0 1 Bifidobacterium myosotis species Increases
0 1 Bifidobacterium porcinum species Increases
0 1 Bifidobacterium pseudocatenulatum species Increases
0 1 Bifidobacterium pseudolongum species Increases
0 1 Bifidobacterium psychraerophilum species Increases
0 1 Bifidobacterium pullorum species Increases
0 1 Bifidobacterium reuteri species Increases
0 1 Bifidobacterium ruminantium species Increases
0 1 Bifidobacterium saguini species Increases
0 1 Bifidobacterium scardovii species Increases
0 1 Bifidobacterium simiae species Increases
0 1 Bifidobacterium stellenboschense species Increases
0 1 Bifidobacterium subtile species Increases
0 1 Bifidobacterium thermacidophilum species Increases
0 1 Bifidobacterium thermophilum species Increases
0 1 Bifidobacterium tissieri species Increases
0 1 Bifidobacterium tsurumiense species Increases
1 0 Lactobacillus intestinalis species Increases
0 1 Bacillus amyloliquefaciens group species subgroup Decreases
0 1 Bifidobacterium animalis subsp. animalis subspecies Decreases
0 1 Bifidobacterium animalis subsp. lactis subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of 4-hydroxyphenyl-beta-D-glucopyranoside {Arbutin} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.6 0.8 -0.33
ADHD 2.4 1.6 0.5
Age-Related Macular Degeneration and Glaucoma 0.3 0.8 -1.67
Allergic Rhinitis (Hay Fever) 1.7 1.8 -0.06
Allergies 3 2.1 0.43
Allergy to milk products 1.6 0.6 1.67
Alopecia (Hair Loss) 1 0.6 0.67
Alzheimer's disease 3.5 4.3 -0.23
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.1 1.5 0.4
Ankylosing spondylitis 3.4 1.4 1.43
Anorexia Nervosa 1.2 2.4 -1
Antiphospholipid syndrome (APS) 0.4 0.4
Asthma 2.8 1.6 0.75
Atherosclerosis 0.4 0.5 -0.25
Atrial fibrillation 2.8 1.5 0.87
Autism 5.9 4.1 0.44
Autoimmune Disease 1.3 0.2 5.5
Barrett esophagus cancer 0.1 0.2 -1
benign prostatic hyperplasia 0.1 0.4 -3
Biofilm 1.5 0.2 6.5
Bipolar Disorder 0.5 0.8 -0.6
Brain Trauma 1.9 0.5 2.8
Breast Cancer 0.8 0.8
Cancer (General) 0.8 0.7 0.14
Carcinoma 1.5 0.6 1.5
Celiac Disease 2.3 3 -0.3
Cerebral Palsy 0.2 0.6 -2
Chronic Fatigue Syndrome 1.9 1.6 0.19
Chronic Kidney Disease 1.4 1.4 0
Chronic Lyme 0.2 -0.2
Chronic Obstructive Pulmonary Disease (COPD) 2.4 1.8 0.33
Chronic Urticaria (Hives) 0.5 0.7 -0.4
Coagulation / Micro clot triggering bacteria 0.6 1.4 -1.33
Cognitive Function 1.6 1.5 0.07
Colorectal Cancer 3.2 1.1 1.91
Constipation 1 0.3 2.33
Coronary artery disease 2.5 1.5 0.67
COVID-19 5.1 4.2 0.21
Crohn's Disease 4.1 3.8 0.08
cystic fibrosis 0.5 0.6 -0.2
d-lactic acidosis (one form of brain fog) 0.2 0.2
deep vein thrombosis 1.1 1.1 0
Denture Wearers Oral Shifts 1.1 0.2 4.5
Depression 6.4 6.1 0.05
Dermatomyositis 0.6 0.6
Eczema 1.4 0.6 1.33
Endometriosis 1.9 1.4 0.36
Eosinophilic Esophagitis 0.1 0.5 -4
Epilepsy 2.6 1.5 0.73
erectile dysfunction 1.1 0.3 2.67
Fibromyalgia 1.6 0.9 0.78
Functional constipation / chronic idiopathic constipation 3.9 1.6 1.44
gallstone disease (gsd) 1.7 0.3 4.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.9 1.3 -0.44
Generalized anxiety disorder 1.8 1.2 0.5
giant cell arteritis 0.5 -0.5
Glioblastoma 1.2 -1.2
Gout 1 0.9 0.11
Graves' disease 0.5 2 -3
Gulf War Syndrome 0.8 0.8 0
Halitosis 0.9 0.6 0.5
Hashimoto's thyroiditis 2 1 1
Heart Failure 2.5 2 0.25
hemorrhagic stroke 1 0.3 2.33
Hemorrhoidal disease, Hemorrhoids, Piles 0.7 0.7
Hidradenitis Suppurativa 0.5 0.3 0.67
High Histamine/low DAO 0.7 0.5 0.4
hypercholesterolemia (High Cholesterol) 0.4 0.4
hyperglycemia 1.7 0.7 1.43
Hyperlipidemia (High Blood Fats) 1.1 1 0.1
hypersomnia 0.3 1.2 -3
hypertension (High Blood Pressure 3.6 3 0.2
Hypothyroidism 1 1.8 -0.8
Hypoxia 0.2 0.4 -1
IgA nephropathy (IgAN) 1.4 1.2 0.17
Inflammatory Bowel Disease 3.8 3.6 0.06
Insomnia 1.7 1.5 0.13
Intelligence 1.4 1.4
Intracranial aneurysms 1.1 0.2 4.5
Irritable Bowel Syndrome 5 2 1.5
ischemic stroke 0.9 1.6 -0.78
Liver Cirrhosis 3.4 1.7 1
Long COVID 4 4.9 -0.23
Low bone mineral density 0.4 1.3 -2.25
Lung Cancer 0.1 1.3 -12
Lymphoma 0.1 0.1
Mast Cell Issues / mastitis 0.7 0.8 -0.14
ME/CFS with IBS 0.3 0.3
ME/CFS without IBS 0.6 0.2 2
membranous nephropathy 0.2 0.2
Menopause 0.6 0.5 0.2
Metabolic Syndrome 4.4 4.9 -0.11
Mood Disorders 5.9 5.6 0.05
multiple chemical sensitivity [MCS] 0.4 0.5 -0.25
Multiple Sclerosis 3.6 1.8 1
Multiple system atrophy (MSA) 0.8 0.5 0.6
myasthenia gravis 1 0.2 4
neuropathic pain 1.2 -1.2
Neuropathy (all types) 1.4 1.1 0.27
neuropsychiatric disorders (PANDAS, PANS) 0.4 0.5 -0.25
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4 2.8 0.43
NonCeliac Gluten Sensitivity 0.8 0.1 7
Obesity 5.7 6.3 -0.11
obsessive-compulsive disorder 1.3 2.2 -0.69
Osteoarthritis 1.8 0.3 5
Osteoporosis 1.8 1.5 0.2
pancreatic cancer 1.3 0.7 0.86
Parkinson's Disease 4.5 5.9 -0.31
Peanut Allergy 0.5 -0.5
Polycystic ovary syndrome 3.3 2 0.65
Postural orthostatic tachycardia syndrome 0.2 0.2 0
Premenstrual dysphoric disorder 0.3 0.2 0.5
primary biliary cholangitis 1.1 1.3 -0.18
Primary sclerosing cholangitis 0.9 2.5 -1.78
Psoriasis 0.6 0.9 -0.5
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.7 3 0.57
Rosacea 0.3 0.2 0.5
Schizophrenia 4 2.3 0.74
scoliosis 1.6 0 0
sensorineural hearing loss 0.5 -0.5
Sjögren syndrome 0.9 1 -0.11
Sleep Apnea 0.9 0.7 0.29
Slow gastric motility / Gastroparesis 0.5 0 0
Small Intestinal Bacterial Overgrowth (SIBO) 1.7 0.4 3.25
Stress / posttraumatic stress disorder 0.9 1.2 -0.33
Systemic Lupus Erythematosus 1.6 2.6 -0.63
Tic Disorder 0.6 0.2 2
Tourette syndrome 0.7 0.3 1.33
Type 1 Diabetes 2.3 1.1 1.09
Type 2 Diabetes 4.5 3.9 0.15
Ulcerative colitis 4.6 2.7 0.7
Unhealthy Ageing 2 0.8 1.5
Vitiligo 1.5 0.2 6.5

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