🍽️ ipsapirone non-drug

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Anxiolytic Effects: Ipsapirone has been studied for its anxiolytic properties, meaning it may help reduce symptoms of anxiety. It is believed to work by modulating serotonin levels in the brain, which can affect mood and anxiety levels.
Antidepressant Effects: Like other serotonin receptor agonists, ipsapirone has been investigated for its potential antidepressant effects. By modulating serotonin signaling, it may help alleviate symptoms of depression in some individuals.
Side Effects: Common side effects associated with ipsapirone use may include dizziness, drowsiness, headache, nausea, and gastrointestinal disturbances. These side effects are typically mild and transient.
Cardiovascular Effects: Ipsapirone may cause changes in heart rate and blood pressure in some individuals. It is important for individuals with cardiovascular conditions to use ipsapirone cautiously and under medical supervision.
Interactions: Ipsapirone may interact with other medications, particularly those that affect serotonin levels in the brain, such as selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and tricyclic antidepressants (TCAs). Combining ipsapirone with these medications may increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by changes in mental status, autonomic dysfunction, and neuromuscular abnormalities.
Withdrawal: Abrupt discontinuation of ipsapirone after long-term use may lead to withdrawal symptoms such as anxiety, insomnia, agitation, and flu-like symptoms. It is recommended to taper off the medication gradually under medical supervision to minimize withdrawal effects.
Liver Function: Ipsapirone may affect liver function, so individuals with pre-existing liver conditions should use it with caution and under medical supervision.

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Data Contradictions — Limits of Certainity

Impacted of ipsapirone non-drug On Probiotics

Rank	Probiotic	Impact
genus	Bifidobacterium	Reduces
species	Akkermansia muciniphila	Reduces
species	Anaerobutyricum hallii	Reduces
species	Bacteroides uniformis	Reduces
species	Bifidobacterium adolescentis	Reduces
species	Bifidobacterium longum	Reduces
species	Blautia wexlerae	Reduces
species	Christensenella minuta	Reduces
species	Escherichia coli	Reduces
species	Faecalibacterium prausnitzii	Reduces
species	Parabacteroides distasonis	Reduces
subspecies	Bifidobacterium longum subsp. infantis	Reduces
subspecies	Bifidobacterium longum subsp. longum	Reduces

Bacteria Impacted by ipsapirone non-drug

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?
📓 Direct Citations	👪👶 Indirect Citations	Taxonomy	Rank	Effect
0	1	Akkermansiaceae	family	Decreases
1	0	Akkermansia	genus	Decreases
0	1	Dorea	genus	Decreases
0	1	Eggerthella	genus	Decreases
0	1	Roseburia	genus	Decreases
0	1	Blautia	genus	Decreases
0	1	Collinsella	genus	Decreases
0	1	Odoribacter	genus	Decreases
0	1	Veillonella	genus	Decreases
0	1	Fusobacterium	genus	Decreases
0	1	Bacteroides	genus	Decreases
0	1	Bilophila	genus	Decreases
0	1	Mediterraneibacter	genus	Decreases
0	1	Clostridium	genus	Decreases
0	1	Segatella	genus	Decreases
0	1	Olsenella	genus	Decreases
0	1	Pseudobutyrivibrio	genus	Decreases
0	1	Phocaeicola	genus	Decreases
0	1	Escherichia	genus	Decreases
0	1	Bifidobacterium	genus	Decreases
0	1	Fannyhessea	genus	Decreases
0	1	Faecalibaculum	genus	Decreases
0	1	Thomasclavelia	genus	Decreases
0	1	Clostridioides	genus	Decreases
0	1	Agathobacter	genus	Decreases
0	1	Parabacteroides	genus	Decreases
0	1	Lacrimispora	genus	Decreases
0	1	Streptococcus	genus	Decreases
0	1	Enterocloster	genus	Decreases
0	1	environmental samples	no rank	Decreases
0	1	unclassified Akkermansia	no rank	Decreases
0	1	Clostridium perfringens A	no rank	Decreases
0	1	Clostridium perfringens B	no rank	Decreases
0	1	Clostridium perfringens C	no rank	Decreases
0	1	Clostridium perfringens CPE	no rank	Decreases
0	1	Clostridium perfringens D	no rank	Decreases
0	1	Clostridium perfringens E	no rank	Decreases
0	1	Escherichia coli O1:K1:H7	no rank	Decreases
0	1	Escherichia coli O139:H1	no rank	Decreases
0	1	Escherichia coli O141:H4	no rank	Decreases
0	1	Escherichia coli O145:H34	no rank	Decreases
0	1	Escherichia coli O15:H12	no rank	Decreases
0	1	Escherichia coli O155:H21	no rank	Decreases
0	1	Escherichia coli O158:H23	no rank	Decreases
0	1	Escherichia coli O16:H48	no rank	Decreases
0	1	Escherichia coli O170:H18	no rank	Decreases
0	1	Escherichia coli O18ac:H14	no rank	Decreases
0	1	Escherichia coli O19:H7	no rank	Decreases
0	1	Escherichia coli O2:K1:H4	no rank	Decreases
0	1	Escherichia coli O2:K1:H5	no rank	Decreases
0	1	Escherichia coli O2:K1:H7	no rank	Decreases
0	1	Escherichia coli O20:H12	no rank	Decreases
0	1	Escherichia coli O25:H16	no rank	Decreases
0	1	Escherichia coli O55:H7	no rank	Decreases
0	1	Escherichia coli O68:H12	no rank	Decreases
0	1	Escherichia coli O7:H15	no rank	Decreases
0	1	Escherichia coli O78:H51	no rank	Decreases
0	1	Escherichia coli O80:H26	no rank	Decreases
0	1	Escherichia coli O84:H7	no rank	Decreases
0	1	Escherichia coli O85:H1	no rank	Decreases
0	1	Escherichia coli O103	serogroup	Decreases
0	1	Escherichia coli O111	serogroup	Decreases
0	1	Escherichia coli O119	serogroup	Decreases
0	1	Escherichia coli O121	serogroup	Decreases
0	1	Escherichia coli O145	serogroup	Decreases
0	1	Escherichia coli O155	serogroup	Decreases
0	1	Escherichia coli O157	serogroup	Decreases
0	1	Escherichia coli O177	serogroup	Decreases
0	1	Escherichia coli O26	serogroup	Decreases
0	1	Escherichia coli O3	serogroup	Decreases
0	1	Escherichia coli O43	serogroup	Decreases
0	1	Escherichia coli O5	serogroup	Decreases
0	1	Escherichia coli O78	serogroup	Decreases
0	1	Escherichia coli O86	serogroup	Decreases
0	1	Escherichia coli O91	serogroup	Decreases
0	1	Escherichia coli H20	serotype	Decreases
0	1	Escherichia coli O1:H42	serotype	Decreases
0	1	Escherichia coli O1:HNT	serotype	Decreases
0	1	Escherichia coli O10:H32	serotype	Decreases
0	1	Escherichia coli O10:K5(L):H4	serotype	Decreases
0	1	Escherichia coli O100:H21	serotype	Decreases
0	1	Escherichia coli O103:H11	serotype	Decreases
0	1	Escherichia coli O103:H2	serotype	Decreases
0	1	Escherichia coli O103:H25	serotype	Decreases
0	1	Escherichia coli O104:H21	serotype	Decreases
0	1	Escherichia coli O104:H4	serotype	Decreases
0	1	Escherichia coli O111:H-	serotype	Decreases
0	1	Escherichia coli O111:H11	serotype	Decreases
0	1	Escherichia coli O111:H8	serotype	Decreases
0	1	Escherichia coli O111:NM	serotype	Decreases
0	1	Escherichia coli O112ab:H8	serotype	Decreases
0	1	Escherichia coli O112ac:H19	serotype	Decreases
0	1	Escherichia coli O113:H21	serotype	Decreases
0	1	Escherichia coli O114:H49	serotype	Decreases
0	1	Escherichia coli O118:H16	serotype	Decreases
0	1	Escherichia coli O121:H19	serotype	Decreases
0	1	Escherichia coli O121:H7	serotype	Decreases
0	1	Escherichia coli O123:H11	serotype	Decreases
0	1	Escherichia coli O125ac:K+:H10	serotype	Decreases
0	1	Escherichia coli O126:H45	serotype	Decreases
0	1	Escherichia coli O127:H27	serotype	Decreases
0	1	Escherichia coli O127:H6	serotype	Decreases
0	1	Escherichia coli O128:H2	serotype	Decreases
0	1	Escherichia coli O128ac:H12	serotype	Decreases
0	1	Escherichia coli O139:H28	serotype	Decreases
0	1	Escherichia coli O145:H25	serotype	Decreases
0	1	Escherichia coli O145:H28	serotype	Decreases
0	1	Escherichia coli O145:NM	serotype	Decreases
0	1	Escherichia coli O146:H21	serotype	Decreases
0	1	Escherichia coli O15:H18	serotype	Decreases
0	1	Escherichia coli O150:H6	serotype	Decreases
0	1	Escherichia coli O152:H23	serotype	Decreases
0	1	Escherichia coli O153:H2	serotype	Decreases
0	1	Escherichia coli O156:H25	serotype	Decreases
0	1	Escherichia coli O157:H-	serotype	Decreases
0	1	Escherichia coli O157:H43	serotype	Decreases
0	1	Escherichia coli O157:H7	serotype	Decreases
0	1	Escherichia coli O157:NM	serotype	Decreases
0	1	Escherichia coli O16:H6	serotype	Decreases
0	1	Escherichia coli O165:H25	serotype	Decreases
0	1	Escherichia coli O167:H26	serotype	Decreases
0	1	Escherichia coli O174:H2	serotype	Decreases
0	1	Escherichia coli O174:H21	serotype	Decreases
0	1	Escherichia coli O174:H8	serotype	Decreases
0	1	Escherichia coli O176:H45	serotype	Decreases
0	1	Escherichia coli O177:NM	serotype	Decreases
0	1	Escherichia coli O2:H6	serotype	Decreases
0	1	Escherichia coli O2:K2:H1	serotype	Decreases
0	1	Escherichia coli O25:H1	serotype	Decreases
0	1	Escherichia coli O25:NM	serotype	Decreases
0	1	Escherichia coli O26:H1	serotype	Decreases
0	1	Escherichia coli O26:H11	serotype	Decreases
0	1	Escherichia coli O28ac:NM	serotype	Decreases
0	1	Escherichia coli O29:H4	serotype	Decreases
0	1	Escherichia coli O32:H37	serotype	Decreases
0	1	Escherichia coli O39:NM	serotype	Decreases
0	1	Escherichia coli O44:H18	serotype	Decreases
0	1	Escherichia coli O45:H2	serotype	Decreases
0	1	Escherichia coli O6:H16	serotype	Decreases
0	1	Escherichia coli O6:H16:CFA/II	serotype	Decreases
0	1	Escherichia coli O6:K2:H1	serotype	Decreases
0	1	Escherichia coli O69:H11	serotype	Decreases
0	1	Escherichia coli O7:H4	serotype	Decreases
0	1	Escherichia coli O7:K1	serotype	Decreases
0	1	Escherichia coli O78:H12	serotype	Decreases
0	1	Escherichia coli O78:H4	serotype	Decreases
0	1	Escherichia coli O79:H7	serotype	Decreases
0	1	Escherichia coli O8:H8	serotype	Decreases
0	1	Escherichia coli O81:NM	serotype	Decreases
0	1	Escherichia coli O83:H1	serotype	Decreases
0	1	Escherichia coli O86:H34	serotype	Decreases
0	1	Escherichia coli O89m:H10	serotype	Decreases
0	1	Escherichia coli O89m:H9	serotype	Decreases
0	1	Escherichia coli O9:H10	serotype	Decreases
0	1	Escherichia coli O91:H14	serotype	Decreases
0	1	Escherichia coli O91:NM	serotype	Decreases
0	1	Escherichia coli O99:H6	serotype	Decreases
0	1	Escherichia coli ONT:H33	serotype	Decreases
1	0	Bacteroides caccae	species	Decreases
1	0	Eggerthella lenta	species	Decreases
1	0	Bacteroides xylanisolvens	species	Decreases
1	0	Akkermansia muciniphila	species	Decreases
1	0	Dorea formicigenerans	species	Decreases
1	0	Roseburia hominis	species	Decreases
1	0	Blautia obeum	species	Decreases
1	0	Collinsella aerofaciens	species	Decreases
1	0	Bacteroides ovatus	species	Decreases
1	0	Odoribacter splanchnicus	species	Decreases
1	0	Veillonella parvula	species	Decreases
1	0	Bifidobacterium adolescentis	species	Decreases
1	0	Fusobacterium nucleatum	species	Decreases
1	0	Bilophila wadsworthia	species	Decreases
1	0	Mediterraneibacter gnavus	species	Decreases
1	0	Clostridium perfringens	species	Decreases
1	0	Segatella copri	species	Decreases
0	1	Eggerthella guodeyinii	species	Decreases
1	0	Phocaeicola vulgatus	species	Decreases
1	0	Escherichia coli	species	Decreases
0	1	Veillonella rodentium	species	Decreases
1	0	Bacteroides fragilis	species	Decreases
1	0	Thomasclavelia ramosa	species	Decreases
0	1	Faecalibacillus intestinalis	species	Decreases
0	1	Coprococcus catus	species	Decreases
0	1	Dorea longicatena	species	Decreases
0	1	Intestinibaculum porci	species	Decreases
0	1	Eubacterium ventriosum	species	Decreases
0	1	Wansuia hejianensis	species	Decreases
0	1	Anaerobutyricum hallii	species	Decreases
0	1	Actinomyces oris	species	Decreases
0	1	Akkermansia glycaniphila	species	Decreases
0	1	Akkermansia massiliensis	species	Decreases
0	1	Candidatus Akkermansia intestinavium	species	Decreases
0	1	[Ruminococcus] torques	species	Decreases
0	1	Pseudobutyrivibrio xylanivorans	species	Decreases
0	1	Blautia sp. SC05B48	species	Decreases
0	1	Adlercreutzia equolifaciens	species	Decreases
0	1	Veillonella dispar	species	Decreases
0	1	Roseburia rectibacter	species	Decreases
0	1	Actinomyces naeslundii	species	Decreases
0	1	Bacteroides luhongzhouii	species	Decreases
0	1	Komagataeibacter oboediens	species	Decreases
1	0	Clostridioides difficile	species	Decreases
0	1	Ligilactobacillus ruminis	species	Decreases
0	1	Coprococcus comes	species	Decreases
0	1	Corynebacterium durum	species	Decreases
0	1	Subdoligranulum variabile	species	Decreases
0	1	Wujia chipingensis	species	Decreases
0	1	Eubacterium sp. MSJ-33	species	Decreases
0	1	Roseburia intestinalis	species	Decreases
0	1	Bacteroides sp. DH3716P	species	Decreases
0	1	Veillonella sp. S12025-13	species	Decreases
0	1	Butyrivibrio crossotus	species	Decreases
0	1	Bacillus paralicheniformis	species	Decreases
0	1	Olsenella sp. oral taxon 807	species	Decreases
0	1	Clostridium sp. SY8519	species	Decreases
0	1	Veillonella nakazawae	species	Decreases
0	1	Ruminococcus bicirculans (ex Wegman et al. 2014)	species	Decreases
0	1	Clostridium sp. M62/1	species	Decreases
0	1	Parolsenella catena	species	Decreases
0	1	Fannyhessea vaginae	species	Decreases
0	1	Monoglobus pectinilyticus	species	Decreases
0	1	Parolsenella massiliensis	species	Decreases
0	1	Anaerostipes hadrus	species	Decreases
0	1	Faecalibacterium duncaniae	species	Decreases
0	1	Simiaoa sunii	species	Decreases
0	1	Ruminococcus gauvreauii	species	Decreases
0	1	Massilistercora timonensis	species	Decreases
0	1	Blautia liquoris	species	Decreases
0	1	[Ruminococcus] lactaris	species	Decreases
0	1	Christensenella minuta	species	Decreases
0	1	Qiania dongpingensis	species	Decreases
0	1	Collinsella stercoris	species	Decreases
0	1	Catenibacterium mitsuokai	species	Decreases
0	1	Treponema denticola	species	Decreases
0	1	Ruminococcus bovis	species	Decreases
0	1	Coprococcus eutactus	species	Decreases
0	1	Faecalibacterium sp. I4-3-84	species	Decreases
0	1	Veillonella rogosae	species	Decreases
0	1	Phascolarctobacterium sp. Marseille-Q4147	species	Decreases
0	1	Maliibacterium massiliense	species	Decreases
0	1	[Clostridium] hylemonae	species	Decreases
0	1	Vescimonas fastidiosa	species	Decreases
0	1	Faecalibacterium prausnitzii	species	Decreases
0	1	Novisyntrophococcus fermenticellae	species	Decreases
0	1	Phascolarctobacterium succinatutens	species	Decreases
0	1	Mogibacterium diversum	species	Decreases
0	1	Phoenicibacter congonensis	species	Decreases
0	1	Ruminococcus albus	species	Decreases
0	1	Faecalitalea cylindroides	species	Decreases
0	1	Faecalibaculum rodentium	species	Decreases
0	1	Vescimonas coprocola	species	Decreases
0	1	Faecalibacterium sp. I3-3-33	species	Decreases
0	1	Ruminococcus champanellensis	species	Decreases
0	1	Parvimonas micra	species	Decreases
1	0	Agathobacter rectalis	species	Decreases
0	1	Mageeibacillus indolicus	species	Decreases
0	1	Romboutsia ilealis	species	Decreases
0	1	Actinomyces sp. oral taxon 171	species	Decreases
0	1	Butyricicoccus sp. GAM44	species	Decreases
0	1	Shigella dysenteriae	species	Decreases
0	1	Segatella bryantii	species	Decreases
0	1	Bacteroides sp. D2	species	Decreases
0	1	Faecalibacterium sp. I2-3-92	species	Decreases
0	1	Oscillibacter hominis	species	Decreases
0	1	uncultured Alistipes sp.	species	Decreases
0	1	Turicibacter bilis	species	Decreases
0	1	Coprococcus sp. ART55/1	species	Decreases
0	1	Faecalibacterium sp. IP-1-18	species	Decreases
1	0	Bacteroides thetaiotaomicron	species	Decreases
0	1	Treponema peruense	species	Decreases
0	1	Faecalibacterium sp. IP-3-29	species	Decreases
0	1	Shigella flexneri	species	Decreases
0	1	Lachnoclostridium phocaeense	species	Decreases
0	1	Escherichia albertii	species	Decreases
0	1	Blautia wexlerae	species	Decreases
0	1	Catenibacterium sp. co_0103	species	Decreases
0	1	Flintibacter sp. KGMB00164	species	Decreases
0	1	Alistipes senegalensis	species	Decreases
0	1	Eubacterium sp. c-25	species	Decreases
0	1	Bifidobacterium angulatum	species	Decreases
0	1	Faecalibacterium sp. I4-1-79	species	Decreases
0	1	Adlercreutzia hattorii	species	Decreases
0	1	Coprobacter secundus	species	Decreases
0	1	Lachnoanaerobaculum gingivalis	species	Decreases
0	1	Lachnospira eligens	species	Decreases
0	1	Actinomyces sp. oral taxon 169	species	Decreases
0	1	Longicatena caecimuris	species	Decreases
0	1	Romboutsia sp. 13368	species	Decreases
0	1	Clostridium cadaveris	species	Decreases
0	1	Alistipes communis	species	Decreases
0	1	Marvinbryantia formatexigens	species	Decreases
0	1	Alistipes shahii	species	Decreases
0	1	Clostridium sp. C1	species	Decreases
0	1	[Eubacterium] hominis	species	Decreases
0	1	Streptococcus suis	species	Decreases
0	1	Anaerotruncus colihominis	species	Decreases
0	1	Faecalibacterium sp. HTF-F	species	Decreases
0	1	Bacteroides sp. M10	species	Decreases
0	1	Alistipes ihumii	species	Decreases
0	1	Intestinimonas butyriciproducens	species	Decreases
1	0	Parabacteroides distasonis	species	Decreases
1	0	Lacrimispora saccharolytica	species	Decreases
1	0	Bifidobacterium longum	species	Decreases
1	0	Bacteroides uniformis	species	Decreases
1	0	Streptococcus salivarius	species	Decreases
1	0	Streptococcus parasanguinis	species	Decreases
1	0	Enterocloster bolteae	species	Decreases
0	1	Fusobacterium nucleatum subsp. nucleatum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. infantis	subspecies	Decreases
0	1	Bifidobacterium longum subsp. longum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suillum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suis	subspecies	Decreases

Impact of ipsapirone non-drug on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition	Positive Impact	Negative Impact	Benefit Ratio Impact
Abdominal Aortic Aneurysm	0.3		0.3
Acne		0.1	-0.1
ADHD	1.9	0.6	2.17
Age-Related Macular Degeneration and Glaucoma	0.9	0	0
Allergic Rhinitis (Hay Fever)	1.8	1.6	0.13
Allergies	4.3	2.5	0.72
Allergy to milk products	1.4	0.6	1.33
Alopecia (Hair Loss)	1.1	0.1	10
Alzheimer's disease	4.7	4.1	0.15
Amyotrophic lateral sclerosis (ALS) Motor Neuron	2.3	0.8	1.87
Ankylosing spondylitis	2.6	0.7	2.71
Anorexia Nervosa	0.6	1.5	-1.5
Antiphospholipid syndrome (APS)	0.5	0.2	1.5
Asthma	3.5	2.4	0.46
Atherosclerosis	1.5	1.5	0
Atrial fibrillation	1.6	1	0.6
Autism	6.5	5.5	0.18
Autoimmune Disease	0.2	0.6	-2
Barrett esophagus cancer	0.4	0	0
benign prostatic hyperplasia	0.1	0.2	-1
Biofilm	1.2		1.2
Bipolar Disorder	1.1	0.8	0.38
Brain Trauma	0.5	0.7	-0.4
Breast Cancer	0.6		0.6
Cancer (General)	0.6	1.5	-1.5
Carcinoma	2.6	1.4	0.86
Celiac Disease	1.5	2.1	-0.4
Cerebral Palsy	1.2	0.7	0.71
Chronic Fatigue Syndrome	3.2	4.2	-0.31
Chronic Kidney Disease	3	1.9	0.58
Chronic Lyme	0.2	0.5	-1.5
Chronic Obstructive Pulmonary Disease (COPD)	0.7	0.7	0
Chronic Urticaria (Hives)	0.7	1.2	-0.71
Coagulation / Micro clot triggering bacteria	0.4	0.7	-0.75
Cognitive Function	1.1	0.8	0.38
Colorectal Cancer	3.9	1.5	1.6
Constipation	0.5	0.5	0
Coronary artery disease	1.2	1.9	-0.58
COVID-19	6.6	8.9	-0.35
Crohn's Disease	5.2	3.9	0.33
Cushing's Syndrome (hypercortisolism)		0.4	-0.4
cystic fibrosis	0.3	1.2	-3
d-lactic acidosis (one form of brain fog)	0.2		0.2
deep vein thrombosis	1.4	0.6	1.33
Denture Wearers Oral Shifts	1		1
Depression	6.5	5.3	0.23
Dermatomyositis	0	0.1	0
Eczema	1.1	0.9	0.22
Endometriosis	1.6	0.9	0.78
Eosinophilic Esophagitis	0.2	0.2	0
Epilepsy	2.7	1.7	0.59
erectile dysfunction	0.6	0.1	5
Fibromyalgia	1.9	1.2	0.58
Functional constipation / chronic idiopathic constipation	2.3	2.4	-0.04
gallstone disease (gsd)	1.9	1.1	0.73
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	1.3	1.1	0.18
Generalized anxiety disorder	2.1	1	1.1
giant cell arteritis		0.2	-0.2
Glioblastoma		0	0
Gout	2	0.7	1.86
Graves' disease	0.8	1.9	-1.37
Gulf War Syndrome	0.4	1.5	-2.75
Halitosis	1	0	0
Hashimoto's thyroiditis	2.6	1.2	1.17
Heart Failure	1.7	1.7	0
hemorrhagic stroke	0.6		0.6
Hidradenitis Suppurativa	0.6	0.2	2
High Histamine/low DAO	1	0.1	9
hypercholesterolemia (High Cholesterol)	0.6	0.6	0
hyperglycemia	1	1.8	-0.8
Hyperlipidemia (High Blood Fats)	1.1	0.2	4.5
hypersomnia		0.7	-0.7
hypertension (High Blood Pressure	2.7	3.4	-0.26
Hypothyroidism	0.5	0.7	-0.4
Hypoxia	1.7		1.7
IgA nephropathy (IgAN)	0.8	2.7	-2.38
Inflammatory Bowel Disease	6.2	6.4	-0.03
Insomnia	1.3	2.2	-0.69
Intelligence	0.8	0.4	1
Intracranial aneurysms	0.7	0.2	2.5
Irritable Bowel Syndrome	5.5	3.2	0.72
ischemic stroke	1.1	0.8	0.38
Juvenile idiopathic arthritis	0.1		0.1
Liver Cirrhosis	4.7	3.3	0.42
Long COVID	4.7	4.9	-0.04
Low bone mineral density		0.6	-0.6
Lung Cancer	1	1.5	-0.5
Lymphoma	0.1		0.1
Mast Cell Issues / mastitis	0.5	0.1	4
ME/CFS with IBS	0.2	2.2	-10
ME/CFS without IBS	1.7	1.6	0.06
membranous nephropathy	0		0
Menopause	1.2	0.9	0.33
Metabolic Syndrome	5.7	5.3	0.08
Mood Disorders	7.2	3.9	0.85
multiple chemical sensitivity [MCS]	0.8	0.4	1
Multiple Sclerosis	4.9	3.2	0.53
Multiple system atrophy (MSA)	1.7	0.4	3.25
myasthenia gravis	0.1	0.4	-3
neuropathic pain	0.3	2.1	-6
Neuropathy (all types)	1.1	1	0.1
neuropsychiatric disorders (PANDAS, PANS)	0.5		0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	3.5	3.6	-0.03
NonCeliac Gluten Sensitivity	1.7	0.3	4.67
Obesity	8.1	5.9	0.37
obsessive-compulsive disorder	2.8	2.6	0.08
Osteoarthritis	1.6	1.1	0.45
Osteoporosis	1.3	1.6	-0.23
pancreatic cancer	0.6	0	0
Parkinson's Disease	5.9	3.7	0.59
Polycystic ovary syndrome	2.9	1.9	0.53
Postural orthostatic tachycardia syndrome	0.2	0.1	1
Premenstrual dysphoric disorder	0.6	0	0
primary biliary cholangitis	0.6	0.7	-0.17
Primary sclerosing cholangitis	1.4	1.8	-0.29
Psoriasis	2.7	1.7	0.59
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	4.9	2.8	0.75
Rosacea	0.3	0.6	-1
Schizophrenia	4.1	1.7	1.41
scoliosis	0.4	0.3	0.33
sensorineural hearing loss	0.3		0.3
Sjögren syndrome	1.8	1.6	0.13
Sleep Apnea	0.9	1.1	-0.22
Slow gastric motility / Gastroparesis	0.6	0.1	5
Small Intestinal Bacterial Overgrowth (SIBO)	1	0.1	9
Stress / posttraumatic stress disorder	2.1	2.2	-0.05
Systemic Lupus Erythematosus	2.5	1.1	1.27
Tic Disorder	0.5	1.3	-1.6
Tourette syndrome	0.9	0.2	3.5
Type 1 Diabetes	2.7	1.8	0.5
Type 2 Diabetes	5.7	4.3	0.33
Ulcerative colitis	3.4	4.8	-0.41
Unhealthy Ageing	3	1.4	1.14
Vitiligo	0.6	1.1	-0.83

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