🍽️ lorglumide sodium salt non-drug

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Gastrointestinal Disorders: Lorglumide sodium salt has been investigated for its therapeutic potential in various gastrointestinal disorders, including functional dyspepsia, irritable bowel syndrome (IBS), and gastroesophageal reflux disease (GERD). As a cholecystokinin receptor antagonist, lorglumide may modulate gastrointestinal motility, reduce visceral hypersensitivity, and decrease gastric acid secretion, which could alleviate symptoms such as abdominal pain, bloating, and reflux.
Pain Management: Cholecystokinin receptors are involved in pain processing, and lorglumide sodium salt has been explored for its analgesic properties. It may exert antinociceptive effects by inhibiting the release of neurotransmitters involved in pain signaling pathways. Research suggests that lorglumide may have potential as an adjuvant therapy for chronic pain conditions, although further studies are needed to elucidate its efficacy and safety profile.
Appetite Regulation and Weight Management: Cholecystokinin plays a role in appetite regulation and satiety signaling. By blocking cholecystokinin receptors, lorglumide sodium salt may modulate appetite and food intake. It has been studied as a potential adjunctive treatment for obesity and eating disorders, although clinical data on its efficacy in this context are limited.
Pancreatitis: Cholecystokinin receptors are also present in the pancreas, where they regulate pancreatic enzyme secretion. Lorglumide sodium salt has been investigated for its potential therapeutic role in acute pancreatitis and chronic pancreatitis by modulating pancreatic exocrine function. However, more research is needed to determine its effectiveness and safety in the management of pancreatic disorders.
Psychiatric Disorders: Cholecystokinin receptors are expressed in the central nervous system, where they modulate neurotransmitter release and synaptic transmission. Lorglumide sodium salt has been studied for its effects on mood, anxiety, and stress-related disorders. Preclinical studies suggest that it may have anxiolytic and antidepressant-like effects, but further clinical trials are necessary to evaluate its efficacy and potential utility in psychiatric practice.
Cancer Therapy: Cholecystokinin receptors are overexpressed in certain types of cancer cells, including pancreatic cancer and neuroendocrine tumors. Lorglumide sodium salt has been investigated as a potential adjuvant therapy for cancer treatment by targeting cholecystokinin receptor-mediated signaling pathways. It may enhance the efficacy of conventional chemotherapy and radiotherapy regimens, although clinical data are limited, and more research is needed to assess its therapeutic potential in oncology.

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Data Contradictions — Limits of Certainity

Impacted of lorglumide sodium salt non-drug On Probiotics

Rank	Probiotic	Impact
genus	Bifidobacterium	Reduces
species	Akkermansia muciniphila	Reduces
species	Anaerobutyricum hallii	Reduces
species	Bacteroides uniformis	Reduces
species	Bifidobacterium adolescentis	Reduces
species	Bifidobacterium bifidum	Reduces
species	Bifidobacterium breve	Reduces
species	Bifidobacterium catenulatum	Reduces
species	Bifidobacterium longum	Reduces
species	Blautia wexlerae	Reduces
species	Christensenella minuta	Reduces
species	Enterococcus faecium	Reduces
species	Escherichia coli	Reduces
species	Lactococcus cremoris	Reduces
species	Lactococcus lactis	Reduces
species	Parabacteroides distasonis	Reduces
species	Streptococcus thermophilus	Reduces
species	Veillonella atypica	Reduces
subspecies	Bifidobacterium longum subsp. infantis	Reduces
subspecies	Bifidobacterium longum subsp. longum	Reduces

Bacteria Impacted by lorglumide sodium salt non-drug

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations	👪👶 Indirect Citations	Taxonomy	Rank	Effect
0	1	Akkermansiaceae	family	Decreases
0	1	Clostridioides	genus	Decreases
0	1	Blautia	genus	Decreases
0	1	Thomasclavelia	genus	Decreases
0	1	Veillonella	genus	Decreases
0	1	Streptococcus	genus	Decreases
0	1	Agathobacter	genus	Decreases
0	1	Clostridium	genus	Decreases
0	1	Bifidobacterium	genus	Decreases
0	1	Mediterraneibacter	genus	Decreases
0	1	Odoribacter	genus	Decreases
0	1	Dorea	genus	Decreases
0	1	Ruminococcus	genus	Decreases
0	1	Roseburia	genus	Decreases
0	1	Segatella	genus	Decreases
0	1	Collinsella	genus	Decreases
0	1	Parabacteroides	genus	Decreases
0	1	Lachnospira	genus	Decreases
0	2	Bacteroides	genus	Decreases
0	1	Bilophila	genus	Decreases
0	1	Lacrimispora	genus	Decreases
0	1	Enterocloster	genus	Decreases
0	1	Anaerostipes	genus	Decreases
1	0	Akkermansia	genus	Decreases
0	1	Anaerobutyricum	genus	Decreases
0	1	Eggerthella	genus	Decreases
0	1	Escherichia	genus	Decreases
0	1	Phocaeicola	genus	Decreases
0	1	Clostridium perfringens A	no rank	Decreases
0	1	Clostridium perfringens B	no rank	Decreases
0	1	Clostridium perfringens C	no rank	Decreases
0	1	Clostridium perfringens CPE	no rank	Decreases
0	1	Clostridium perfringens D	no rank	Decreases
0	1	Clostridium perfringens E	no rank	Decreases
0	1	Escherichia coli O1:K1:H7	no rank	Decreases
0	1	Escherichia coli O139:H1	no rank	Decreases
0	1	Escherichia coli O141:H4	no rank	Decreases
0	1	Escherichia coli O145:H34	no rank	Decreases
0	1	Escherichia coli O15:H12	no rank	Decreases
0	1	Escherichia coli O155:H21	no rank	Decreases
0	1	Escherichia coli O158:H23	no rank	Decreases
0	1	Escherichia coli O16:H48	no rank	Decreases
0	1	Escherichia coli O170:H18	no rank	Decreases
0	1	Escherichia coli O18ac:H14	no rank	Decreases
0	1	Escherichia coli O19:H7	no rank	Decreases
0	1	Escherichia coli O2:K1:H4	no rank	Decreases
0	1	Escherichia coli O2:K1:H5	no rank	Decreases
0	1	Escherichia coli O2:K1:H7	no rank	Decreases
0	1	Escherichia coli O20:H12	no rank	Decreases
0	1	Escherichia coli O25:H16	no rank	Decreases
0	1	Escherichia coli O55:H7	no rank	Decreases
0	1	Escherichia coli O68:H12	no rank	Decreases
0	1	Escherichia coli O7:H15	no rank	Decreases
0	1	Escherichia coli O78:H51	no rank	Decreases
0	1	Escherichia coli O80:H26	no rank	Decreases
0	1	Escherichia coli O84:H7	no rank	Decreases
0	1	Escherichia coli O85:H1	no rank	Decreases
0	1	environmental samples	no rank	Decreases
0	1	unclassified Akkermansia	no rank	Decreases
0	1	Escherichia coli O103	serogroup	Decreases
0	1	Escherichia coli O111	serogroup	Decreases
0	1	Escherichia coli O119	serogroup	Decreases
0	1	Escherichia coli O121	serogroup	Decreases
0	1	Escherichia coli O145	serogroup	Decreases
0	1	Escherichia coli O155	serogroup	Decreases
0	1	Escherichia coli O157	serogroup	Decreases
0	1	Escherichia coli O177	serogroup	Decreases
0	1	Escherichia coli O26	serogroup	Decreases
0	1	Escherichia coli O3	serogroup	Decreases
0	1	Escherichia coli O43	serogroup	Decreases
0	1	Escherichia coli O5	serogroup	Decreases
0	1	Escherichia coli O78	serogroup	Decreases
0	1	Escherichia coli O86	serogroup	Decreases
0	1	Escherichia coli O91	serogroup	Decreases
0	1	Escherichia coli H20	serotype	Decreases
0	1	Escherichia coli O1:H42	serotype	Decreases
0	1	Escherichia coli O1:HNT	serotype	Decreases
0	1	Escherichia coli O10:H32	serotype	Decreases
0	1	Escherichia coli O10:K5(L):H4	serotype	Decreases
0	1	Escherichia coli O100:H21	serotype	Decreases
0	1	Escherichia coli O103:H11	serotype	Decreases
0	1	Escherichia coli O103:H2	serotype	Decreases
0	1	Escherichia coli O103:H25	serotype	Decreases
0	1	Escherichia coli O104:H21	serotype	Decreases
0	1	Escherichia coli O104:H4	serotype	Decreases
0	1	Escherichia coli O111:H-	serotype	Decreases
0	1	Escherichia coli O111:H11	serotype	Decreases
0	1	Escherichia coli O111:H8	serotype	Decreases
0	1	Escherichia coli O111:NM	serotype	Decreases
0	1	Escherichia coli O112ab:H8	serotype	Decreases
0	1	Escherichia coli O112ac:H19	serotype	Decreases
0	1	Escherichia coli O113:H21	serotype	Decreases
0	1	Escherichia coli O114:H49	serotype	Decreases
0	1	Escherichia coli O118:H16	serotype	Decreases
0	1	Escherichia coli O121:H19	serotype	Decreases
0	1	Escherichia coli O121:H7	serotype	Decreases
0	1	Escherichia coli O123:H11	serotype	Decreases
0	1	Escherichia coli O125ac:K+:H10	serotype	Decreases
0	1	Escherichia coli O126:H45	serotype	Decreases
0	1	Escherichia coli O127:H27	serotype	Decreases
0	1	Escherichia coli O127:H6	serotype	Decreases
0	1	Escherichia coli O128:H2	serotype	Decreases
0	1	Escherichia coli O128ac:H12	serotype	Decreases
0	1	Escherichia coli O139:H28	serotype	Decreases
0	1	Escherichia coli O145:H25	serotype	Decreases
0	1	Escherichia coli O145:H28	serotype	Decreases
0	1	Escherichia coli O145:NM	serotype	Decreases
0	1	Escherichia coli O146:H21	serotype	Decreases
0	1	Escherichia coli O15:H18	serotype	Decreases
0	1	Escherichia coli O150:H6	serotype	Decreases
0	1	Escherichia coli O152:H23	serotype	Decreases
0	1	Escherichia coli O153:H2	serotype	Decreases
0	1	Escherichia coli O156:H25	serotype	Decreases
0	1	Escherichia coli O157:H-	serotype	Decreases
0	1	Escherichia coli O157:H43	serotype	Decreases
0	1	Escherichia coli O157:H7	serotype	Decreases
0	1	Escherichia coli O157:NM	serotype	Decreases
0	1	Escherichia coli O16:H6	serotype	Decreases
0	1	Escherichia coli O165:H25	serotype	Decreases
0	1	Escherichia coli O167:H26	serotype	Decreases
0	1	Escherichia coli O174:H2	serotype	Decreases
0	1	Escherichia coli O174:H21	serotype	Decreases
0	1	Escherichia coli O174:H8	serotype	Decreases
0	1	Escherichia coli O176:H45	serotype	Decreases
0	1	Escherichia coli O177:NM	serotype	Decreases
0	1	Escherichia coli O2:H6	serotype	Decreases
0	1	Escherichia coli O2:K2:H1	serotype	Decreases
0	1	Escherichia coli O25:H1	serotype	Decreases
0	1	Escherichia coli O25:NM	serotype	Decreases
0	1	Escherichia coli O26:H1	serotype	Decreases
0	1	Escherichia coli O26:H11	serotype	Decreases
0	1	Escherichia coli O28ac:NM	serotype	Decreases
0	1	Escherichia coli O29:H4	serotype	Decreases
0	1	Escherichia coli O32:H37	serotype	Decreases
0	1	Escherichia coli O39:NM	serotype	Decreases
0	1	Escherichia coli O44:H18	serotype	Decreases
0	1	Escherichia coli O45:H2	serotype	Decreases
0	1	Escherichia coli O6:H16	serotype	Decreases
0	1	Escherichia coli O6:H16:CFA/II	serotype	Decreases
0	1	Escherichia coli O6:K2:H1	serotype	Decreases
0	1	Escherichia coli O69:H11	serotype	Decreases
0	1	Escherichia coli O7:H4	serotype	Decreases
0	1	Escherichia coli O7:K1	serotype	Decreases
0	1	Escherichia coli O78:H12	serotype	Decreases
0	1	Escherichia coli O78:H4	serotype	Decreases
0	1	Escherichia coli O79:H7	serotype	Decreases
0	1	Escherichia coli O8:H8	serotype	Decreases
0	1	Escherichia coli O81:NM	serotype	Decreases
0	1	Escherichia coli O83:H1	serotype	Decreases
0	1	Escherichia coli O86:H34	serotype	Decreases
0	1	Escherichia coli O89m:H10	serotype	Decreases
0	1	Escherichia coli O89m:H9	serotype	Decreases
0	1	Escherichia coli O9:H10	serotype	Decreases
0	1	Escherichia coli O91:H14	serotype	Decreases
0	1	Escherichia coli O91:NM	serotype	Decreases
0	1	Escherichia coli O99:H6	serotype	Decreases
0	1	Escherichia coli ONT:H33	serotype	Decreases
1	0	Agathobacter rectalis	species	Decreases
1	0	Clostridium perfringens	species	Decreases
1	0	Mediterraneibacter gnavus	species	Decreases
1	0	Odoribacter splanchnicus	species	Decreases
1	0	Streptococcus parasanguinis	species	Decreases
1	0	Dorea formicigenerans	species	Decreases
1	0	Bacteroides caccae	species	Decreases
1	0	Bacteroides ovatus	species	Decreases
1	0	Bacteroides thetaiotaomicron	species	Decreases
1	0	Bacteroides xylanisolvens	species	Decreases
1	0	Bifidobacterium adolescentis	species	Decreases
1	0	Blautia obeum	species	Decreases
1	0	Clostridioides difficile	species	Decreases
1	0	Parabacteroides distasonis	species	Decreases
1	0	Roseburia hominis	species	Decreases
1	0	Streptococcus salivarius	species	Decreases
1	0	Thomasclavelia ramosa	species	Decreases
1	0	Veillonella parvula	species	Decreases
1	0	Ruminococcus bromii	species	Decreases
1	0	Bacteroides fragilis	species	Decreases
1	0	Bifidobacterium longum	species	Decreases
1	0	Segatella copri	species	Decreases
1	0	Collinsella aerofaciens	species	Decreases
1	0	Lachnospira eligens	species	Decreases
0	1	Streptococcus sp. FDAARGOS_192	species	Decreases
0	1	Streptococcus sp. LPB0220	species	Decreases
0	1	Streptococcus sp. HSISM1	species	Decreases
0	1	Veillonella rodentium	species	Decreases
1	0	Bilophila wadsworthia	species	Decreases
0	1	Veillonella dispar	species	Decreases
1	0	Lacrimispora saccharolytica	species	Decreases
1	0	Enterocloster bolteae	species	Decreases
1	0	Akkermansia muciniphila	species	Decreases
0	1	Veillonella sp. S12025-13	species	Decreases
0	1	Veillonella nakazawae	species	Decreases
0	1	Bifidobacterium angulatum	species	Decreases
0	1	Bifidobacterium breve	species	Decreases
0	1	Segatella bryantii	species	Decreases
0	1	Streptococcus vestibularis	species	Decreases
0	1	Actinomyces oris	species	Decreases
0	1	Streptococcus lactarius	species	Decreases
0	1	Bacteroides sp. DH3716P	species	Decreases
0	1	Coprococcus catus	species	Decreases
0	1	Anaerobutyricum hallii	species	Decreases
0	1	Veillonella rogosae	species	Decreases
0	1	Adlercreutzia equolifaciens	species	Decreases
2	0	Bacteroides uniformis	species	Decreases
0	1	Dorea longicatena	species	Decreases
0	1	Actinomyces naeslundii	species	Decreases
0	1	Wansuia hejianensis	species	Decreases
1	0	Eggerthella lenta	species	Decreases
0	1	Blautia sp. SC05B48	species	Decreases
0	1	Corynebacterium durum	species	Decreases
0	1	Streptococcus gordonii	species	Decreases
0	1	Streptococcus australis	species	Decreases
0	1	Komagataeibacter oboediens	species	Decreases
0	1	Streptococcus sp. oral taxon 061	species	Decreases
0	1	Eubacterium ventriosum	species	Decreases
0	1	Bacillus paralicheniformis	species	Decreases
0	1	Bacteroides luhongzhouii	species	Decreases
0	1	Butyrivibrio crossotus	species	Decreases
0	1	Ligilactobacillus ruminis	species	Decreases
0	1	Olsenella sp. oral taxon 807	species	Decreases
0	1	Coprococcus comes	species	Decreases
0	1	Mogibacterium diversum	species	Decreases
0	1	Parvimonas micra	species	Decreases
0	1	Alistipes megaguti	species	Decreases
0	1	Eubacterium sp. MSJ-33	species	Decreases
0	1	Parolsenella catena	species	Decreases
0	1	uncultured Alistipes sp.	species	Decreases
0	1	Fannyhessea vaginae	species	Decreases
0	1	Subdoligranulum variabile	species	Decreases
0	1	Streptococcus infantis	species	Decreases
0	1	Clostridium sp. M62/1	species	Decreases
0	1	Veillonella atypica	species	Decreases
0	1	Roseburia rectibacter	species	Decreases
0	1	Streptococcus oralis	species	Decreases
0	1	[Ruminococcus] torques	species	Decreases
0	1	Faecalibacillus intestinalis	species	Decreases
0	1	Clostridium sp. SY8519	species	Decreases
0	1	Wujia chipingensis	species	Decreases
0	1	Eubacterium sp. c-25	species	Decreases
0	1	Blautia liquoris	species	Decreases
0	1	Qiania dongpingensis	species	Decreases
0	1	Coprobacter fastidiosus	species	Decreases
0	1	Blautia argi	species	Decreases
0	1	Ruminococcus gauvreauii	species	Decreases
0	1	Leyella stercorea	species	Decreases
0	1	Intestinibaculum porci	species	Decreases
0	1	Pseudobutyrivibrio xylanivorans	species	Decreases
0	1	Novisyntrophococcus fermenticellae	species	Decreases
0	1	[Eubacterium] hominis	species	Decreases
0	1	Treponema denticola	species	Decreases
0	1	Faecalibacterium duncaniae	species	Decreases
0	1	Coprococcus eutactus	species	Decreases
1	0	Escherichia coli	species	Decreases
0	1	Faecalitalea cylindroides	species	Decreases
0	1	Mageeibacillus indolicus	species	Decreases
0	1	Massilistercora timonensis	species	Decreases
0	1	Anaerostipes hadrus	species	Decreases
0	1	Streptococcus suis	species	Decreases
0	1	Phoenicibacter congonensis	species	Decreases
0	1	Streptococcus sp. oral taxon 431	species	Decreases
0	1	[Ruminococcus] lactaris	species	Decreases
0	1	Ruminococcus albus	species	Decreases
0	1	Eubacterium limosum	species	Decreases
0	1	Parolsenella massiliensis	species	Decreases
0	1	Alistipes ihumii	species	Decreases
0	1	Phascolarctobacterium succinatutens	species	Decreases
0	1	Christensenella minuta	species	Decreases
0	1	Faecalibaculum rodentium	species	Decreases
0	1	Streptococcus sp. Marseille-Q6470	species	Decreases
0	1	Simiaoa sunii	species	Decreases
0	1	Bifidobacterium catenulatum	species	Decreases
0	1	Actinomyces sp. oral taxon 171	species	Decreases
0	1	[Clostridium] hylemonae	species	Decreases
0	1	Ruminococcus bicirculans (ex Wegman et al. 2014)	species	Decreases
0	1	Bacteroides sp. D2	species	Decreases
0	1	Catenibacterium mitsuokai	species	Decreases
0	1	Monoglobus pectinilyticus	species	Decreases
0	1	Adlercreutzia hattorii	species	Decreases
0	1	Alistipes dispar	species	Decreases
0	1	Eubacterium callanderi	species	Decreases
0	1	Marvinbryantia formatexigens	species	Decreases
0	1	Lactococcus cremoris	species	Decreases
0	1	Butyricicoccus sp. GAM44	species	Decreases
0	1	Lachnoclostridium phocaeense	species	Decreases
0	1	Vescimonas fastidiosa	species	Decreases
0	1	Streptococcus ilei	species	Decreases
0	1	Streptococcus sanguinis	species	Decreases
0	1	Maliibacterium massiliense	species	Decreases
0	1	Eubacterium maltosivorans	species	Decreases
0	1	Longicatena caecimuris	species	Decreases
0	1	Coprococcus sp. ART55/1	species	Decreases
0	1	Collinsella stercoris	species	Decreases
0	1	Vescimonas coprocola	species	Decreases
0	1	Faecalibacterium sp. I4-3-84	species	Decreases
0	1	Clostridium cadaveris	species	Decreases
1	0	Roseburia intestinalis	species	Decreases
0	1	Enterococcus faecium	species	Decreases
0	1	Ruminococcus champanellensis	species	Decreases
0	1	Faecalibacterium sp. I4-1-79	species	Decreases
0	1	Faecalibacterium sp. I3-3-33	species	Decreases
0	1	Oscillibacter hominis	species	Decreases
0	1	Faecalibacterium sp. I2-3-92	species	Decreases
0	1	Actinomyces sp. oral taxon 169	species	Decreases
0	1	Faecalibacterium sp. IP-1-18	species	Decreases
0	1	Emergencia timonensis	species	Decreases
0	1	Lachnoanaerobaculum gingivalis	species	Decreases
0	1	Clostridium sp. C1	species	Decreases
0	1	Faecalibacterium sp. IP-3-29	species	Decreases
0	1	Solibaculum mannosilyticum	species	Decreases
0	1	Bacteroides sp. M10	species	Decreases
0	1	Phascolarctobacterium sp. Marseille-Q4147	species	Decreases
0	1	Acutalibacter muris	species	Decreases
0	1	Bacteroides nordii	species	Decreases
0	1	Faecalibacterium sp. HTF-F	species	Decreases
0	1	[Clostridium] scindens	species	Decreases
0	1	Prevotella intermedia	species	Decreases
0	1	Anaerotruncus colihominis	species	Decreases
0	1	Lactococcus lactis	species	Decreases
0	1	Blautia wexlerae	species	Decreases
0	1	Amedibacterium intestinale	species	Decreases
0	1	Catenibacterium sp. co_0103	species	Decreases
0	1	Bifidobacterium bifidum	species	Decreases
0	1	Treponema peruense	species	Decreases
0	1	Gordonibacter urolithinfaciens	species	Decreases
0	1	Streptococcus mutans	species	Decreases
0	1	Ruthenibacterium lactatiformans	species	Decreases
0	1	Alistipes sp. dk3624	species	Decreases
0	1	Streptococcus sp. A12	species	Decreases
0	1	Faecalibacterium sp. I3-3-89	species	Decreases
0	1	Ruminococcus bovis	species	Decreases
0	1	Enterococcus cecorum	species	Decreases
0	1	Butyrivibrio fibrisolvens	species	Decreases
0	1	Chordicoccus furentiruminis	species	Decreases
0	1	Campylobacter coli	species	Decreases
0	1	Flintibacter sp. KGMB00164	species	Decreases
0	1	Rothia dentocariosa	species	Decreases
0	1	Leyella lascolaii	species	Decreases
0	1	Bacteroides faecium	species	Decreases
0	1	Lancefieldella parvula	species	Decreases
0	1	Blautia parvula	species	Decreases
0	1	Streptococcus pasteurianus	species	Decreases
0	1	Streptococcus cristatus	species	Decreases
0	1	Arabiibacter massiliensis	species	Decreases
0	1	Olsenella uli	species	Decreases
0	1	Streptococcus thermophilus	species	Decreases
0	1	Akkermansia glycaniphila	species	Decreases
0	1	Akkermansia massiliensis	species	Decreases
0	1	Candidatus Akkermansia intestinavium	species	Decreases
1	0	Phocaeicola vulgatus	species	Decreases
1	0	Parabacteroides merdae	species	Decreases
0	1	Bacteroides uniformis ATCC 8492	strain	Increases
0	1	Bacteroides uniformis CL03T00C23	strain	Increases
0	1	Bacteroides uniformis CL03T12C37	strain	Increases
0	1	Bacteroides uniformis dnLKV2	strain	Increases
0	1	Bacteroides uniformis str. 3978 T3 i	strain	Increases
0	1	Bacteroides uniformis str. 3978 T3 ii	strain	Increases
0	1	Bifidobacterium longum subsp. infantis	subspecies	Decreases
0	1	Bifidobacterium longum subsp. longum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suillum	subspecies	Decreases
0	1	Bifidobacterium longum subsp. suis	subspecies	Decreases

Impact of lorglumide sodium salt non-drug on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition	Positive Impact	Negative Impact	Benefit Ratio Impact
Abdominal Aortic Aneurysm	0.7		0.7
Acne		0.3	-0.3
ADHD	3.9	0.4	8.75
Age-Related Macular Degeneration and Glaucoma	0.7	0.2	2.5
Allergic Rhinitis (Hay Fever)	3.1	3	0.03
Allergies	6.3	3	1.1
Allergy to milk products	1.3	0.9	0.44
Alopecia (Hair Loss)	1.7	0.1	16
Alzheimer's disease	4.7	6.6	-0.4
Amyotrophic lateral sclerosis (ALS) Motor Neuron	2.4	0.7	2.43
Ankylosing spondylitis	3.9	1.2	2.25
Anorexia Nervosa	2	3.3	-0.65
Antiphospholipid syndrome (APS)	1.2	0.1	11
Asthma	5.1	2.4	1.13
Atherosclerosis	2	1.5	0.33
Atrial fibrillation	3.6	2	0.8
Autism	7.9	8.4	-0.06
Autoimmune Disease	0.8	0.9	-0.13
Barrett esophagus cancer	0.4	0.4	0
benign prostatic hyperplasia	0.1	0.1	0
Biofilm	2.6		2.6
Bipolar Disorder	1.2	1.1	0.09
Brain Trauma	1	1	0
Breast Cancer	0.1		0.1
Cancer (General)	0.8	2.9	-2.62
Carcinoma	2.9	2.3	0.26
Celiac Disease	2.5	3.6	-0.44
Cerebral Palsy	1.6	1.2	0.33
Chronic Fatigue Syndrome	5.1	6.1	-0.2
Chronic Kidney Disease	3.6	2	0.8
Chronic Lyme	0.6	0.3	1
Chronic Obstructive Pulmonary Disease (COPD)	2.4	1.2	1
Chronic Urticaria (Hives)	1.3	1.3	0
Coagulation / Micro clot triggering bacteria	0.8	1.5	-0.88
Cognitive Function	1.8	1.6	0.13
Colorectal Cancer	5.4	2	1.7
Constipation	0.7	0.7	0
Coronary artery disease	2.2	3.1	-0.41
COVID-19	9.3	13.3	-0.43
Crohn's Disease	6.4	4.9	0.31
Cushing's Syndrome (hypercortisolism)		0.1	-0.1
cystic fibrosis	0.2	1.7	-7.5
d-lactic acidosis (one form of brain fog)	0.2		0.2
deep vein thrombosis	1.1	1.1	0
Denture Wearers Oral Shifts	1.8		1.8
Depression	9.2	7.4	0.24
Dermatomyositis	0.4	0.3	0.33
Eczema	1.8	2.8	-0.56
Endometriosis	2	1.6	0.25
Eosinophilic Esophagitis		0.8	-0.8
Epilepsy	3.2	1.4	1.29
erectile dysfunction	0.5	0.3	0.67
Fibromyalgia	2.9	1.5	0.93
Functional constipation / chronic idiopathic constipation	4.2	4	0.05
gallstone disease (gsd)	3.7	0.7	4.29
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	1.1	1.9	-0.73
Generalized anxiety disorder	2.1	1.7	0.24
giant cell arteritis		0.3	-0.3
Glioblastoma		0.5	-0.5
Gout	2	0.4	4
Graves' disease	1.6	3	-0.88
Gulf War Syndrome	1.1	1.8	-0.64
Halitosis	0.9	0.5	0.8
Hashimoto's thyroiditis	3.2	1	2.2
Heart Failure	3.3	2.4	0.38
hemorrhagic stroke	0.5		0.5
Hidradenitis Suppurativa	0.8	0.4	1
High Histamine/low DAO	1.4	0.6	1.33
hypercholesterolemia (High Cholesterol)	0.8	0.3	1.67
hyperglycemia	1.7	1.4	0.21
Hyperlipidemia (High Blood Fats)	0.8	0.2	3
hypersomnia		0.8	-0.8
hypertension (High Blood Pressure	3.1	5.7	-0.84
Hypothyroidism	0.2	1	-4
Hypoxia	2.1		2.1
IgA nephropathy (IgAN)	1.1	5.1	-3.64
Inflammatory Bowel Disease	8.1	10.2	-0.26
Insomnia	2.4	2.7	-0.13
Intelligence	1	0.5	1
Intracranial aneurysms	1.2	0.2	5
Irritable Bowel Syndrome	6.4	3.8	0.68
ischemic stroke	2.8	0.7	3
Liver Cirrhosis	6.7	3	1.23
Long COVID	6.6	7.5	-0.14
Low bone mineral density		0.8	-0.8
Lung Cancer	0.8	1.5	-0.88
Lymphoma	0.1		0.1
Mast Cell Issues / mastitis	0.4	0.6	-0.5
ME/CFS with IBS	0.9	2.3	-1.56
ME/CFS without IBS	1.9	2.1	-0.11
membranous nephropathy	0.4		0.4
Menopause	2.5	0.5	4
Metabolic Syndrome	6.6	6.8	-0.03
Mood Disorders	10	6.1	0.64
multiple chemical sensitivity [MCS]	1.6	0.5	2.2
Multiple Sclerosis	6.3	6.7	-0.06
Multiple system atrophy (MSA)	1.6	1.1	0.45
myasthenia gravis	0.4	0.6	-0.5
neuropathic pain	0.1	2.3	-22
Neuropathy (all types)	1	1.2	-0.2
neuropsychiatric disorders (PANDAS, PANS)	0.8		0.8
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	5	4.9	0.02
NonCeliac Gluten Sensitivity	1.4	0.4	2.5
Obesity	9.3	7.2	0.29
obsessive-compulsive disorder	4.8	3.8	0.26
Osteoarthritis	3	1.3	1.31
Osteoporosis	1.5	1.7	-0.13
pancreatic cancer	0.7	0.4	0.75
Parkinson's Disease	7.2	7.1	0.01
Polycystic ovary syndrome	5.4	3.2	0.69
Postural orthostatic tachycardia syndrome	0.3	0.3	0
Premenstrual dysphoric disorder	1	0.2	4
primary biliary cholangitis	1.1	1	0.1
Primary sclerosing cholangitis	3	3.6	-0.2
Psoriasis	4.1	2.6	0.58
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	6.8	4	0.7
Rosacea	0.8	0.6	0.33
Schizophrenia	6.7	2.8	1.39
scoliosis	0.3	0.8	-1.67
sensorineural hearing loss	0.3		0.3
Sjögren syndrome	3.1	2.4	0.29
Sleep Apnea	1.4	1	0.4
Slow gastric motility / Gastroparesis	0.9	0.3	2
Small Intestinal Bacterial Overgrowth (SIBO)	1.5	0.5	2
Stress / posttraumatic stress disorder	1.9	1.5	0.27
Systemic Lupus Erythematosus	3.7	2.1	0.76
Tic Disorder	1	1.8	-0.8
Tourette syndrome	0.8	0.1	7
Type 1 Diabetes	3.8	3.4	0.12
Type 2 Diabetes	6.8	5.7	0.19
Ulcerative colitis	5.1	6.3	-0.24
Unhealthy Ageing	3.6	1.9	0.89
Vitiligo	2	1.1	0.82

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