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Depression: St. John's Wort is perhaps best known for its use in treating mild to moderate depression. Hypericin, along with other compounds found in the plant, is believed to act as a natural antidepressant by inhibiting the reuptake of certain neurotransmitters such as serotonin, dopamine, and norepinephrine in the brain. This may help improve mood and alleviate symptoms of depression.
Anxiety: Some studies suggest that St. John's Wort may also have anxiolytic (anti-anxiety) effects, although the evidence is not as robust as it is for depression. Hypericin and other components of St. John's Wort may help reduce symptoms of anxiety and promote relaxation.
Seasonal Affective Disorder (SAD): St. John's Wort has been used as a natural remedy for seasonal affective disorder, a type of depression that occurs seasonally, typically during the winter months when daylight hours are shorter. Hypericin may help regulate mood and energy levels in individuals with SAD.
Obsessive-Compulsive Disorder (OCD): Some preliminary research suggests that St. John's Wort may be beneficial for individuals with obsessive-compulsive disorder (OCD), a mental health condition characterized by obsessive thoughts and compulsive behaviors. Hypericin may help modulate neurotransmitter activity in the brain, thereby reducing symptoms of OCD.
Neuralgia and Nerve Pain: St. John's Wort has been traditionally used to alleviate nerve pain and neuralgia. Hypericin may have analgesic (pain-relieving) properties that help reduce pain associated with conditions such as sciatica, shingles, and neuropathy.
Wound Healing: Hypericin has been studied for its potential wound healing properties. Some research suggests that it may help promote the formation of new blood vessels and accelerate the healing process in skin wounds and burns when applied topically.
Antiviral Activity: Hypericin has been shown to exhibit antiviral activity against certain viruses, including herpes simplex virus (HSV) and human immunodeficiency virus (HIV). It may help inhibit viral replication and reduce the severity and duration of viral infections.
Anti-inflammatory Effects: St. John's Wort has been found to possess anti-inflammatory properties, which may help reduce inflammation in the body and alleviate symptoms of inflammatory conditions such as arthritis and inflammatory bowel disease.
Goatweed,Klamath weed,Tipton's weed,Rosin rose,Hypericum,Millepertuis,Johanniskraut
Rank | Probiotic | Impact |
---|---|---|
genus | Bacillus | Reduces |
genus | Bifidobacterium | Increases |
species | Akkermansia muciniphila | Increases |
species | Alkalihalophilus pseudofirmus | Reduces |
species | Bacillus aeolius | Reduces |
species | Bacillus horti | Reduces |
species | Bacillus infernus | Reduces |
species | Bacillus licheniformis | Reduces |
species | Bacillus pumilus | Reduces |
species | Bacillus subtilis | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
5 | 0 | Staphylococcus aureus | species | Decreases |
3 | 0 | Bacillus subtilis | species | Decreases |
3 | 0 | Enterococcus faecalis | species | Decreases |
3 | 0 | Escherichia coli | species | Decreases |
3 | 0 | Klebsiella pneumoniae | species | Decreases |
2 | 0 | Mycobacterium | genus | Decreases |
2 | 0 | Candida albicans | species | Decreases |
2 | 0 | Micrococcus luteus | species | Decreases |
2 | 0 | Staphylococcus epidermidis | species | Decreases |
1 | 5 | Staphylococcus | genus | Decreases |
1 | 2 | Escherichia | genus | Decreases |
1 | 2 | Klebsiella | genus | Decreases |
1 | 2 | Enterococcus | genus | Decreases |
1 | 2 | Bacillus subtilis group | species group | Decreases |
1 | 1 | Mycobacteriaceae | family | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.5 | 0.2 | 1.5 |
Acne | 2.7 | 1.7 | 0.59 |
Addison's Disease (hypocortisolism) | 0.5 | 0.5 | |
ADHD | 2.9 | 5.5 | -0.9 |
Age-Related Macular Degeneration and Glaucoma | 1.1 | 1 | 0.1 |
Allergic Rhinitis (Hay Fever) | 5.1 | 3.5 | 0.46 |
Allergies | 9.6 | 7.3 | 0.32 |
Allergy to milk products | 5.2 | 2.8 | 0.86 |
Alopecia (Hair Loss) | 2.9 | 1.2 | 1.42 |
Alzheimer's disease | 12.4 | 12.1 | 0.02 |
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