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Digestive Health: Probiotics containing Lactobacillus helveticus and Lactobacillus rhamnosus may contribute to digestive health by promoting a balanced gut microbiota and supporting gastrointestinal function. They can help alleviate symptoms of digestive disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diarrhea by modulating gut inflammation, enhancing gut barrier function, and producing beneficial metabolites.
Immune Function: The combination of Lactobacillus helveticus and Lactobacillus rhamnosus may have immunomodulatory effects, meaning they can help regulate the immune system. They may enhance immune function by stimulating the production of certain immune cells and cytokines, thereby reducing the risk of infections and supporting overall immune health.
Women's Health: Probiotics containing these strains may benefit women's health by promoting vaginal health and reducing the risk of urogenital infections such as bacterial vaginosis and urinary tract infections (UTIs). They can help restore the balance of vaginal microbiota and create an acidic environment that inhibits the growth of harmful bacteria.
Mental Health: There is evidence to suggest that supplementation with Lactobacillus helveticus and Lactobacillus rhamnosus may have beneficial effects on mental health and mood regulation. Some research indicates that these strains may have anxiolytic (anxiety-reducing) and antidepressant effects, potentially by modulating neurotransmitter levels, reducing inflammation, and promoting gut-brain communication via the gut microbiota-brain axis.
Cholesterol Metabolism: Some research suggests that supplementation with Lactobacillus helveticus and Lactobacillus rhamnosus may help improve lipid profiles by lowering total cholesterol and LDL cholesterol levels and increasing HDL cholesterol levels. These effects may be mediated by the metabolism of bile acids and the production of bioactive compounds that inhibit cholesterol absorption.
Blood Pressure Regulation: There is evidence to suggest that certain strains of Lactobacillus helveticus and Lactobacillus rhamnosus may have antihypertensive effects, meaning they can help lower blood pressure. These effects may be attributed to the production of bioactive peptides, such as ACE-inhibitory peptides, which can help regulate blood pressure by inhibiting the activity of angiotensin-converting enzyme (ACE).
l helveticus,l rhamnosus (probiotics)
Rank | Probiotic | Impact |
---|---|---|
genus | Bacillus | Reduces |
genus | Bifidobacterium | Reduces |
genus | Pediococcus | Increases |
species | Akkermansia muciniphila | Increases |
species | Bacillus aeolius | Reduces |
species | Bacillus horti | Reduces |
species | Bacillus infernus | Reduces |
species | Bacillus pumilus | Reduces |
species | Bacillus thermotolerans | Reduces |
species | Bacillus thuringiensis | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
5 | 0 | Lactobacillus | genus | Increases |
4 | 1 | Bacteroides | genus | Decreases |
4 | 0 | Akkermansia | genus | Increases |
4 | 0 | Akkermansia muciniphila | species | Increases |
3 | 1 | Bifidobacterium | genus | Decreases |
3 | 0 | Enterococcus | genus | Increases |
3 | 0 | Bacillota | phylum | Decreases |
3 | 0 | Candida albicans | species | Decreases |
3 | 0 | Roseburia faecis | species | Decreases |
2 | 2 | Enterobacteriaceae | family | Decreases |
2 | 2 | Salmonella | genus | Decreases |
2 | 1 | Citrobacter | genus | Decreases |
2 | 0 | Ruminococcaceae | family | Decreases |
2 | 0 | Blautia | genus | Increases |
2 | 0 | Escherichia coli | species | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.5 | 0.5 | |
Acne | 2.3 | 2 | 0.15 |
Addison's Disease (hypocortisolism) | 0.5 | 0.5 | |
ADHD | 2.7 | 2.9 | -0.07 |
Age-Related Macular Degeneration and Glaucoma | 0.6 | -0.6 | |
Allergic Rhinitis (Hay Fever) | 3.4 | 3.6 | -0.06 |
Allergies | 7.3 | 6.3 | 0.16 |
Allergy to milk products | 2.3 | 4.4 | -0.91 |
Alopecia (Hair Loss) | 1.4 | 1.6 | -0.14 |
Alzheimer's disease | 12.5 | 12.2 | 0.02 |
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