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Digestive Health: Lactobacillus plantarum may contribute to digestive health by promoting a balanced gut microbiota, aiding in the breakdown of food, and producing beneficial metabolites such as short-chain fatty acids. It may help alleviate symptoms of digestive disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diarrhea by modulating gut inflammation, enhancing gut barrier function, and promoting regular bowel movements.
Immune Function: Lactobacillus plantarum has immunomodulatory properties and may help enhance immune function. It can stimulate the production of certain immune cells and cytokines, promoting a balanced immune response and reducing the risk of infections and inflammatory conditions.
Allergies and Atopic Conditions: Some research suggests that supplementation with Lactobacillus plantarum may help reduce the risk of allergic conditions such as eczema, allergic rhinitis, and asthma. It may exert its effects by modulating immune responses and promoting immune tolerance, thereby reducing allergic reactions and inflammation.
Cholesterol Metabolism: Some studies have suggested that supplementation with Lactobacillus plantarum may help improve lipid profiles by lowering total cholesterol and LDL cholesterol levels and increasing HDL cholesterol levels. These effects may be mediated by the metabolism of bile acids and the production of bioactive compounds that inhibit cholesterol absorption.
Liver Health: Lactobacillus plantarum has been studied for its potential hepatoprotective effects, meaning it may help protect the liver from damage caused by toxins, alcohol, or certain medications. It may also help improve liver function and reduce inflammation in individuals with liver diseases such as non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD).
Mental Health: There is emerging evidence to suggest that Lactobacillus plantarum may have beneficial effects on mental health and mood regulation. Some research indicates that supplementation with L. plantarum may help reduce symptoms of anxiety and depression, potentially by modulating neurotransmitter levels, reducing inflammation, and promoting gut-brain communication via the gut microbiota-brain axis.
lactobacillus plantarum, Lactobacillus arabinosus
Rank | Probiotic | Impact |
---|---|---|
genus | Bacillus | Reduces |
genus | Bifidobacterium | Increases |
genus | Pediococcus | Increases |
species | Akkermansia muciniphila | Increases |
species | Alkalihalophilus pseudofirmus | Reduces |
species | Bacillus aeolius | Reduces |
species | Bacillus horti | Reduces |
species | Bacillus infernus | Reduces |
species | Bacillus pumilus | Reduces |
species | Bacillus thermotolerans | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
28 | 5 | Lactobacillus | genus | Increases |
26 | 0 | Bifidobacterium | genus | Increases |
17 | 1 | Akkermansia | genus | Increases |
15 | 2 | Bacteroides | genus | Increases |
12 | 6 | Escherichia coli | species | Decreases |
11 | 13 | Escherichia | genus | Decreases |
11 | 3 | Staphylococcus | genus | Decreases |
10 | 4 | Staphylococcus aureus | species | Decreases |
10 | 1 | Alistipes | genus | Increases |
10 | 1 | Bacillota | phylum | Decreases |
9 | 4 | Ruminococcus | genus | Increases |
9 | 2 | Clostridium | genus | Decreases |
8 | 22 | Lactobacillaceae | family | Increases |
8 | 6 | Roseburia | genus | Increases |
8 | 0 | Pseudomonas aeruginosa | species | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 1.6 | 0.5 | 2.2 |
Acne | 4.8 | 1.7 | 1.82 |
Addison's Disease (hypocortisolism) | 0.3 | 0.3 | |
ADHD | 5.2 | 7.9 | -0.52 |
Age-Related Macular Degeneration and Glaucoma | 0.3 | 0.5 | -0.67 |
Allergic Rhinitis (Hay Fever) | 8.8 | 5.2 | 0.69 |
Allergies | 12.5 | 11.1 | 0.13 |
Allergy to milk products | 4.1 | 4.7 | -0.15 |
Alopecia (Hair Loss) | 4.6 | 1.4 | 2.29 |
Alzheimer's disease | 22.4 | 14.4 | 0.56 |
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