🍽️ a-Gluco-oligosaccharides {GOS}

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Gut health: Gluco-oligosaccharides act as prebiotics, nourishing beneficial bacteria in the gut such as Bifidobacteria and Lactobacilli. By promoting the growth of these probiotic bacteria, gluco-oligosaccharides help maintain a healthy balance of gut flora, which is essential for digestion, nutrient absorption, and immune function. A healthy gut microbiota can help prevent gastrointestinal disorders such as irritable bowel syndrome (IBS), inflammatory bowel diseases (IBD), and diarrhea.
Improved digestion: Gluco-oligosaccharides increase stool bulk and promote regular bowel movements, which can help alleviate symptoms of constipation and promote overall digestive health. By supporting bowel regularity, gluco-oligosaccharides may reduce the risk of colorectal cancer and other digestive disorders.
Immune support: Gluco-oligosaccharides have immunomodulatory properties and may help enhance the body's immune response. They stimulate the activity of immune cells such as macrophages, natural killer cells, and T cells, helping to strengthen the immune system's defense against infections and diseases. Gluco-oligosaccharides may be beneficial for individuals with weakened immune systems or recurrent infections.
Bone health: Some studies suggest that gluco-oligosaccharides may have beneficial effects on bone health. They have been shown to enhance calcium absorption and promote bone formation, which may help prevent osteoporosis and reduce the risk of fractures, especially in postmenopausal women who are at higher risk of bone loss.
Weight management: Gluco-oligosaccharides can contribute to feelings of fullness and satiety when consumed as part of a meal or snack. By delaying gastric emptying and increasing the release of satiety hormones, gluco-oligosaccharides may help control appetite and reduce calorie intake, which can support weight loss or weight management efforts.
Blood sugar control: Gluco-oligosaccharides may help regulate blood sugar levels by slowing down the absorption of carbohydrates in the intestines. This can help prevent rapid spikes in blood glucose levels after meals and improve insulin sensitivity, making it beneficial for individuals with diabetes or insulin resistance. Gluco-oligosaccharides may also contribute to feelings of fullness and satiety, which can aid in blood sugar control and weight management.

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Data Contradictions — Limits of Certainity

Impacted of a-Gluco-oligosaccharides {GOS} On Probiotics

Rank	Probiotic	Impact
genus	Bifidobacterium	Increases
genus	Saccharomyces	Increases
species	Bifidobacterium adolescentis	Increases
species	Bifidobacterium animalis	Increases
species	Bifidobacterium bifidum	Increases
species	Bifidobacterium breve	Increases
species	Bifidobacterium catenulatum	Increases
species	Bifidobacterium longum	Increases
species	Bifidobacterium pseudocatenulatum	Increases
species	Bifidobacterium pseudolongum	Increases
species	Faecalibacterium prausnitzii	Reduces
species	Lacticaseibacillus casei	Increases
species	Lactiplantibacillus pentosus	Increases
species	Lactiplantibacillus plantarum	Increases
species	Lactobacillus acidophilus	Increases
species	Lactobacillus crispatus	Increases
species	Lactobacillus gasseri	Increases
species	Lactobacillus helveticus	Increases
species	Lactobacillus jensenii	Increases
species	Lactobacillus johnsonii	Increases
species	Lactobacillus kefiranofaciens	Increases
species	Saccharomyces cerevisiae	Increases

Bacteria Impacted by a-Gluco-oligosaccharides {GOS}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?
📓 Direct Citations	👪👶 Indirect Citations	Taxonomy	Rank	Effect
0	1	Oscillospiraceae	family	Decreases
0	2	Bifidobacteriaceae	family	Increases
0	1	Burkholderiaceae	family	Increases
0	1	Lactobacillaceae	family	Increases
1	0	Faecalibacterium	genus	Decreases
0	1	Lacticaseibacillus	genus	Increases
0	1	Lactiplantibacillus	genus	Increases
0	1	Saccharomyces	genus	Increases
1	0	Lactobacillus	genus	Increases
1	0	Weissella	genus	Increases
2	0	Bifidobacterium	genus	Increases
0	1	environmental samples	no rank	Decreases
0	1	unclassified Faecalibacterium	no rank	Decreases
0	1	environmental samples	no rank	Increases
0	1	environmental samples	no rank	Increases
0	1	environmental samples	no rank	Increases
0	1	unclassified Burkholderia	no rank	Increases
0	1	unclassified Lactobacillus	no rank	Increases
0	1	unclassified Lactobacillus casei group	no rank	Increases
0	1	unclassified Weissella	no rank	Increases
0	2	environmental samples	no rank	Increases
0	2	unclassified Bifidobacterium	no rank	Increases
1	0	Faecalibacterium prausnitzii	species	Decreases
0	1	Faecalibacterium duncaniae	species	Decreases
0	1	Faecalibacterium hattorii	species	Decreases
0	1	Faecalibacterium hominis (ex Afrizal et al. 2022)	species	Decreases
0	1	Faecalibacterium longum	species	Decreases
0	2	Bifidobacterium saguini	species	Increases
0	1	Lactobacillus ultunensis	species	Increases
0	2	Bifidobacterium pseudolongum	species	Increases
0	2	Bifidobacterium asteroides	species	Increases
0	2	Bifidobacterium subtile	species	Increases
0	2	Bifidobacterium pullorum	species	Increases
0	2	Bifidobacterium animalis	species	Increases
0	1	Weissella koreensis	species	Increases
0	2	Bifidobacterium scardovii	species	Increases
0	2	Bifidobacterium imperatoris	species	Increases
0	2	Bifidobacterium thermophilum	species	Increases
0	2	Bifidobacterium lemurum	species	Increases
0	1	Lactobacillus helveticus	species	Increases
0	2	Bifidobacterium eulemuris	species	Increases
0	1	Lactobacillus johnsonii	species	Increases
0	1	Lactobacillus kefiranofaciens	species	Increases
0	1	Lactobacillus amylolyticus	species	Increases
0	2	Bifidobacterium dentium	species	Increases
0	1	Weissella hellenica	species	Increases
0	1	Lactobacillus acetotolerans	species	Increases
0	1	Lactobacillus amylovorus	species	Increases
0	1	Lactobacillus iners	species	Increases
0	1	Lactobacillus taiwanensis	species	Increases
0	2	Bifidobacterium choerinum	species	Increases
0	1	Lactobacillus crispatus	species	Increases
0	1	Lactobacillus intestinalis	species	Increases
0	1	Weissella paramesenteroides	species	Increases
0	1	Lactobacillus acidophilus	species	Increases
0	1	Weissella viridescens	species	Increases
0	1	Lactobacillus paragasseri	species	Increases
0	1	Weissella jogaejeotgali	species	Increases
0	2	Bifidobacterium pseudocatenulatum	species	Increases
0	1	Lactobacillus jensenii	species	Increases
0	1	Weissella soli	species	Increases
0	1	Lactobacillus gasseri	species	Increases
0	1	[Lactobacillus] rogosae	species	Increases
0	1	ATCC 15434	species	Increases
0	1	Burkholderia glumae	species	Increases
0	1	Burkholderia plantarii	species	Increases
0	1	Burkholderia rinojensis	species	Increases
0	1	Burkholderia sp. Bp5365	species	Increases
0	1	Burkholderia sp. OLGA172	species	Increases
0	1	Lactobacillus alvei	species	Increases
0	1	Lactobacillus animata	species	Increases
0	1	Lactobacillus apis	species	Increases
0	1	Lactobacillus bombicola	species	Increases
0	1	Lactobacillus brevisimilis	species	Increases
0	1	Lactobacillus casei subsp. casei ATCC 393	species	Increases
0	1	Lactobacillus equicursoris	species	Increases
0	1	Lactobacillus faeni	species	Increases
0	1	Lactobacillus fornicalis	species	Increases
0	1	Lactobacillus gallinarum	species	Increases
0	1	Lactobacillus gigeriorum	species	Increases
0	1	Lactobacillus guizhouensis	species	Increases
0	1	Lactobacillus hamsteri	species	Increases
0	1	Lactobacillus helsingborgensis	species	Increases
0	1	Lactobacillus hominis	species	Increases
0	1	Lactobacillus intermedius	species	Increases
0	1	Lactobacillus japonicus	species	Increases
0	1	Lactobacillus kalixensis	species	Increases
0	1	Lactobacillus kitasatonis	species	Increases
0	1	Lactobacillus kullabergensis	species	Increases
0	1	Lactobacillus leichmannii	species	Increases
0	1	Lactobacillus letivazi	species	Increases
0	1	Lactobacillus mulieris	species	Increases
0	1	Lactobacillus panisapium	species	Increases
0	1	Lactobacillus pasteurii	species	Increases
0	1	Lactobacillus psittaci	species	Increases
0	1	Lactobacillus rodentium	species	Increases
0	1	Lactobacillus selangorensis	species	Increases
0	1	Lactobacillus sp. 7_1_47FAA	species	Increases
0	1	Lactobacillus sp. MYMRS/TEN2	species	Increases
0	1	Lactobacillus terrae	species	Increases
0	1	Weissella ceti	species	Increases
0	1	Weissella coleopterorum	species	Increases
0	1	Weissella diestrammenae	species	Increases
0	1	Weissella halotolerans	species	Increases
0	1	Weissella hanii	species	Increases
0	1	Weissella kandleri	species	Increases
0	1	Weissella minor	species	Increases
0	1	Weissella oryzae	species	Increases
0	1	Weissella salipiscis	species	Increases
0	1	Weissella thailandensis	species	Increases
0	1	Weissella tructae	species	Increases
0	1	Weissella uvarum	species	Increases
0	1	Lactobacillus delbrueckii	species	Increases
0	2	Bifidobacterium angulatum	species	Increases
0	1	Burkholderia gladioli	species	Increases
0	2	Bifidobacterium bifidum	species	Increases
0	2	Bifidobacterium adolescentis	species	Increases
0	1	Weissella confusa	species	Increases
0	2	Bifidobacterium catenulatum	species	Increases
0	2	Bifidobacterium actinocoloniiforme	species	Increases
0	2	Bifidobacterium aesculapii	species	Increases
0	2	Bifidobacterium avesanii	species	Increases
0	2	Bifidobacterium biavatii	species	Increases
0	2	Bifidobacterium bohemicum	species	Increases
0	2	Bifidobacterium bombi	species	Increases
0	2	Bifidobacterium boum	species	Increases
0	2	Bifidobacterium callitrichidarum	species	Increases
0	2	Bifidobacterium callitrichos	species	Increases
0	2	Bifidobacterium commune	species	Increases
0	2	Bifidobacterium coryneforme	species	Increases
0	2	Bifidobacterium cuniculi	species	Increases
0	2	Bifidobacterium faecale	species	Increases
0	2	Bifidobacterium gallicum	species	Increases
0	2	Bifidobacterium indicum	species	Increases
0	2	Bifidobacterium magnum	species	Increases
0	2	Bifidobacterium merycicum	species	Increases
0	2	Bifidobacterium minimum	species	Increases
0	2	Bifidobacterium mongoliense	species	Increases
0	2	Bifidobacterium moukalabense	species	Increases
0	2	Bifidobacterium myosotis	species	Increases
0	2	Bifidobacterium porcinum	species	Increases
0	2	Bifidobacterium psychraerophilum	species	Increases
0	2	Bifidobacterium reuteri	species	Increases
0	2	Bifidobacterium ruminantium	species	Increases
0	2	Bifidobacterium simiae	species	Increases
0	2	Bifidobacterium stellenboschense	species	Increases
0	2	Bifidobacterium stercoris	species	Increases
0	2	Bifidobacterium thermacidophilum	species	Increases
0	2	Bifidobacterium tissieri	species	Increases
0	2	Bifidobacterium tsurumiense	species	Increases
1	0	Lacticaseibacillus casei	species	Increases
1	0	Lactiplantibacillus pentosus	species	Increases
1	0	Lactiplantibacillus plantarum	species	Increases
1	0	Saccharomyces cerevisiae	species	Increases
1	0	Weissella cibaria	species	Increases
0	2	Bifidobacterium breve	species	Increases
0	2	Bifidobacterium longum	species	Increases
0	1	Burkholderia cepacia complex	species group	Increases
0	1	pseudomallei group	species group	Increases
1	0	Lactobacillus casei group	species group	Increases
0	1	Faecalibacterium prausnitzii L2-6	strain	Decreases
0	1	Faecalibacterium cf. prausnitzii KLE1255	strain	Decreases
0	1	Faecalibacterium prausnitzii M21/2	strain	Decreases
0	1	Faecalibacterium prausnitzii SL3/3	strain	Decreases
0	1	Lacticaseibacillus casei 12A	strain	Increases
0	1	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	strain	Increases
0	1	Lacticaseibacillus casei Lpc-37	strain	Increases
0	1	Lacticaseibacillus casei UW4	strain	Increases
0	1	Lacticaseibacillus casei W56	strain	Increases
0	1	Lactiplantibacillus plantarum 16	strain	Increases
0	1	Lactiplantibacillus plantarum UCMA 3037	strain	Increases
0	1	Lactiplantibacillus plantarum WCFS1	strain	Increases
0	1	Weissella cibaria KACC 11862	strain	Increases
0	1	Lactiplantibacillus plantarum subsp. plantarum	subspecies	Increases

Impact of a-Gluco-oligosaccharides {GOS} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition	Positive Impact	Negative Impact	Benefit Ratio Impact
Acne	1.4		1.4
ADHD	1.2	1.8	-0.5
Age-Related Macular Degeneration and Glaucoma		0.2	-0.2
Allergic Rhinitis (Hay Fever)	2.3	1.1	1.09
Allergies	2.1	3.8	-0.81
Allergy to milk products	1.3	0.1	12
Alzheimer's disease	1.8	2.4	-0.33
Amyotrophic lateral sclerosis (ALS) Motor Neuron	0.5	1.2	-1.4
Ankylosing spondylitis	1.4	0.6	1.33
Anorexia Nervosa	0.6	1.6	-1.67
Asthma	2.1	2.7	-0.29
Atherosclerosis	1	1.7	-0.7
Atrial fibrillation	1.1	1.7	-0.55
Autism	4.3	2.9	0.48
Autoimmune Disease	1.3	1.1	0.18
benign prostatic hyperplasia		0.7	-0.7
Biofilm		0.8	-0.8
Bipolar Disorder	1	1.1	-0.1
Brain Trauma	1.2	1.6	-0.33
Breast Cancer		0.6	-0.6
Cancer (General)	3.1		3.1
Carcinoma	0.6	0.6	0
Celiac Disease	1.8	2.5	-0.39
Cerebral Palsy		1.1	-1.1
Chronic Fatigue Syndrome	1.2	1.6	-0.33
Chronic Kidney Disease	0.8	1.1	-0.38
Chronic Obstructive Pulmonary Disease (COPD)		0.8	-0.8
Chronic Urticaria (Hives)		1	-1
Cognitive Function	1.9	1.3	0.46
Colorectal Cancer	1.4	1.9	-0.36
Constipation	0.2	0.5	-1.5
Coronary artery disease	0.6	1	-0.67
COVID-19	2.3	3.7	-0.61
Crohn's Disease	2.2	3.1	-0.41
cystic fibrosis	0.8	0.7	0.14
d-lactic acidosis (one form of brain fog)		3	-3
deep vein thrombosis	0.6		0.6
Denture Wearers Oral Shifts	0.6	0	0
Depression	3.3	4.7	-0.42
Dermatomyositis	0.6		0.6
Eczema	2	0.1	19
Endometriosis	1.9	1.2	0.58
Epilepsy	2.2	1.1	1
erectile dysfunction	0.6	0.2	2
Fibromyalgia	1.2	2.2	-0.83
Functional constipation / chronic idiopathic constipation	2.1	1.6	0.31
gallstone disease (gsd)	1.7	0.7	1.43
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	0.7		0.7
Generalized anxiety disorder	1.3	0.5	1.6
Glioblastoma		0.7	-0.7
Gout	0		0
Graves' disease	1.2	1.7	-0.42
Gulf War Syndrome	0.6	0	0
Hashimoto's thyroiditis	1.4	1.6	-0.14
Heart Failure	1.7	1.6	0.06
High Histamine/low DAO	0.6	1.7	-1.83
hypercholesterolemia (High Cholesterol)	0.6	0.5	0.2
hyperglycemia	2.3	0.5	3.6
Hyperlipidemia (High Blood Fats)	0.8	1.1	-0.38
hypertension (High Blood Pressure	2.1	3	-0.43
Hypothyroidism	0.8	0.7	0.14
Hypoxia	1.2	1.2	0
IgA nephropathy (IgAN)	1.2		1.2
Inflammatory Bowel Disease	2.9	2.2	0.32
Insomnia	0.2	1.5	-6.5
Intelligence	0.2	0.6	-2
Intracranial aneurysms	1.4	0.5	1.8
Irritable Bowel Syndrome	2.5	2.2	0.14
ischemic stroke		2.7	-2.7
Liver Cirrhosis	1.9	1.7	0.12
Long COVID	3.1	2.6	0.19
Low bone mineral density		0.2	-0.2
Lung Cancer		0.7	-0.7
Mast Cell Issues / mastitis	0.6		0.6
ME/CFS with IBS	0.6	1	-0.67
ME/CFS without IBS	0.6		0.6
Menopause	0.7	1.2	-0.71
Metabolic Syndrome	2.7	3.4	-0.26
Mood Disorders	3.8	4.5	-0.18
multiple chemical sensitivity [MCS]		1.1	-1.1
Multiple Sclerosis	2.2	2.9	-0.32
Multiple system atrophy (MSA)	0.7	0.6	0.17
myasthenia gravis	0.5	0.5	0
neuropathic pain		1	-1
Neuropathy (all types)		1.6	-1.6
neuropsychiatric disorders (PANDAS, PANS)		0.5	-0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	2.1	1.8	0.17
NonCeliac Gluten Sensitivity	1.4	1.1	0.27
Obesity	4	2.9	0.38
obsessive-compulsive disorder	1.7	0.5	2.4
Osteoarthritis	0.7	1	-0.43
Osteoporosis	1.4	1.7	-0.21
pancreatic cancer	0.2		0.2
Parkinson's Disease	2.4	3.5	-0.46
Polycystic ovary syndrome	1.7	1.9	-0.12
Postural orthostatic tachycardia syndrome	0.6		0.6
Premenstrual dysphoric disorder		0.6	-0.6
primary biliary cholangitis		1.3	-1.3
Primary sclerosing cholangitis		1.6	-1.6
Psoriasis	0.5	1.2	-1.4
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	2.1	2.8	-0.33
Rosacea	1.2	1.1	0.09
Schizophrenia	1.6	3.4	-1.13
scoliosis	0.2		0.2
Sjögren syndrome	1.8	1.2	0.5
Sleep Apnea	0.2	1.1	-4.5
Slow gastric motility / Gastroparesis	1.2		1.2
Small Intestinal Bacterial Overgrowth (SIBO)	0.7	0.6	0.17
Stress / posttraumatic stress disorder	1.2	2.2	-0.83
Systemic Lupus Erythematosus	1.4	1.1	0.27
Tic Disorder	1.3		1.3
Tourette syndrome	0.6	0.2	2
Type 1 Diabetes	2.5	1.6	0.56
Type 2 Diabetes	2	3.2	-0.6
Ulcerative colitis	3.3	3.6	-0.09
Unhealthy Ageing	1.4	1.1	0.27
Vitiligo	0.6	0.6	0

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