AI Engines For more Details: Perplexity Kagi Labs You
Pain Relief: Hydromorphone is highly effective in managing severe pain, such as that associated with surgery, cancer, or other conditions where milder pain medications are insufficient.
Opioid Analgesia: It works by binding to opioid receptors in the brain and spinal cord, thereby altering the perception of pain and producing analgesia.
Respiratory Depression: Like other opioids, hydromorphone can cause respiratory depression, which is a slowing or cessation of breathing. This effect can be dose-dependent and is more likely to occur at higher doses or in individuals with respiratory conditions.
Sedation and Drowsiness: Hydromorphone can cause sedation and drowsiness, which can impair a person's ability to perform tasks requiring alertness, such as driving or operating machinery.
Nausea and Vomiting: Common side effects of hydromorphone include nausea and vomiting, particularly when first starting the medication or with dose adjustments.
Constipation: Opioids like hydromorphone commonly cause constipation by slowing down the movement of the gastrointestinal tract.
Addiction and Dependence: There is a risk of developing addiction or dependence with prolonged use of hydromorphone, especially in individuals with a history of substance abuse or addiction.
Tolerance: With repeated use, the body may develop tolerance to the effects of hydromorphone, requiring higher doses to achieve the same level of pain relief.
Withdrawal Symptoms: Abrupt discontinuation of hydromorphone can lead to withdrawal symptoms, which may include flu-like symptoms, agitation, anxiety, insomnia, and drug craving.
Overdose: Taking too much hydromorphone can lead to overdose, which can be life-threatening and may result in respiratory failure, coma, or death.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Pseudomonas putida | Increases |
| species group | Pseudomonas putida group | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| 📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
|---|---|---|---|---|
| 0 | 1 | Sphingomonadaceae | family | Decreases |
| 0 | 3 | Pseudomonadaceae | family | Increases |
| 1 | 0 | Sphingomonas | genus | Decreases |
| 3 | 0 | Pseudomonas | genus | Increases |
| 0 | 1 | environmental samples | no rank | Decreases |
| 0 | 1 | unclassified Sphingomonas | no rank | Decreases |
| 0 | 3 | environmental samples | no rank | Increases |
| 0 | 3 | unclassified Pseudomonas | no rank | Increases |
| 0 | 3 | unclassified Pseudomonas | norank | Increases |
| 1 | 0 | Sphingomonas paucimobilis | species | Decreases |
| 0 | 1 | Sphingomonas abaci | species | Decreases |
| 0 | 1 | Sphingomonas adhaesiva | species | Decreases |
| 0 | 1 | Sphingomonas aerophila | species | Decreases |
| 0 | 1 | Sphingomonas aliaeris | species | Decreases |
| 0 | 1 | Sphingomonas alpina | species | Decreases |
| 0 | 1 | Sphingomonas anadarae | species | Decreases |
| 0 | 1 | Sphingomonas asaccharolytica | species | Decreases |
| 0 | 1 | Sphingomonas astaxanthinifaciens | species | Decreases |
| 0 | 1 | Sphingomonas azotifigens | species | Decreases |
| 0 | 1 | Sphingomonas bisphenolicum | species | Decreases |
| 0 | 1 | Sphingomonas cannabina | species | Decreases |
| 0 | 1 | Sphingomonas changbaiensis | species | Decreases |
| 0 | 1 | Sphingomonas changnyeongensis | species | Decreases |
| 0 | 1 | Sphingomonas cynarae | species | Decreases |
| 0 | 1 | Sphingomonas daechungensis | species | Decreases |
| 0 | 1 | Sphingomonas desiccabilis | species | Decreases |
| 0 | 1 | Sphingomonas dokdonensis | species | Decreases |
| 0 | 1 | Sphingomonas donggukensis | species | Decreases |
| 0 | 1 | Sphingomonas echinoides | species | Decreases |
| 0 | 1 | Sphingomonas elodea | species | Decreases |
| 0 | 1 | Sphingomonas endophytica | species | Decreases |
| 0 | 1 | Sphingomonas ginsengisoli (ex Hoang et al. 2012) | species | Decreases |
| 0 | 1 | Sphingomonas ginsengisoli An et al. 2013 | species | Decreases |
| 0 | 1 | Sphingomonas ginsenosidimutans | species | Decreases |
| 0 | 1 | Sphingomonas glaciei | species | Decreases |
| 0 | 1 | Sphingomonas guangdongensis | species | Decreases |
| 0 | 1 | Sphingomonas haloaromaticamans | species | Decreases |
| 0 | 1 | Sphingomonas hengshuiensis | species | Decreases |
| 0 | 1 | Sphingomonas humi | species | Decreases |
| 0 | 1 | Sphingomonas hunanensis | species | Decreases |
| 0 | 1 | Sphingomonas insulae | species | Decreases |
| 0 | 1 | Sphingomonas japonica | species | Decreases |
| 0 | 1 | Sphingomonas jaspsi | species | Decreases |
| 0 | 1 | Sphingomonas jinjuensis | species | Decreases |
| 0 | 1 | Sphingomonas koreensis | species | Decreases |
| 0 | 1 | Sphingomonas lacunae | species | Decreases |
| 0 | 1 | Sphingomonas leidyi | species | Decreases |
| 0 | 1 | Sphingomonas lutea | species | Decreases |
| 0 | 1 | Sphingomonas mali | species | Decreases |
| 0 | 1 | Sphingomonas molluscorum | species | Decreases |
| 0 | 1 | Sphingomonas morindae | species | Decreases |
| 0 | 1 | Sphingomonas mucosissima | species | Decreases |
| 0 | 1 | Sphingomonas naphthae | species | Decreases |
| 0 | 1 | Sphingomonas nostoxanthinifaciens | species | Decreases |
| 0 | 1 | Sphingomonas olei | species | Decreases |
| 0 | 1 | Sphingomonas oligophenolica | species | Decreases |
| 0 | 1 | Sphingomonas paeninsulae | species | Decreases |
| 0 | 1 | Sphingomonas panacis | species | Decreases |
| 0 | 1 | Sphingomonas panacisoli | species | Decreases |
| 0 | 1 | Sphingomonas panni | species | Decreases |
| 0 | 1 | Sphingomonas parapaucimobilis | species | Decreases |
| 0 | 1 | Sphingomonas piscis | species | Decreases |
| 0 | 1 | Sphingomonas polyaromaticivorans | species | Decreases |
| 0 | 1 | Sphingomonas profundi | species | Decreases |
| 0 | 1 | Sphingomonas pruni | species | Decreases |
| 0 | 1 | Sphingomonas psychrotolerans | species | Decreases |
| 0 | 1 | Sphingomonas radiodurans | species | Decreases |
| 0 | 1 | Sphingomonas rhizophila | species | Decreases |
| 0 | 1 | Sphingomonas roseiflava | species | Decreases |
| 0 | 1 | Sphingomonas rubra | species | Decreases |
| 0 | 1 | Sphingomonas sabuli | species | Decreases |
| 0 | 1 | Sphingomonas sanguinis | species | Decreases |
| 0 | 1 | Sphingomonas sanxanigenens | species | Decreases |
| 0 | 1 | Sphingomonas sediminicola | species | Decreases |
| 0 | 1 | Sphingomonas sinipercae | species | Decreases |
| 0 | 1 | Sphingomonas soli | species | Decreases |
| 0 | 1 | Sphingomonas suaedae | species | Decreases |
| 0 | 1 | Sphingomonas taxi | species | Decreases |
| 0 | 1 | Sphingomonas xanthus | species | Decreases |
| 0 | 1 | Sphingomonas yabuuchiae | species | Decreases |
| 0 | 1 | Sphingomonas yunnanensis | species | Decreases |
| 0 | 1 | Sphingomonas aerolata | species | Decreases |
| 0 | 1 | Sphingomonas hankookensis | species | Decreases |
| 0 | 1 | Sphingomonas melonis | species | Decreases |
| 0 | 3 | Pseudomonas psychrophila | species | Increases |
| 0 | 3 | Pseudomonas chengduensis | species | Increases |
| 0 | 3 | Pseudomonas phenolilytica | species | Increases |
| 0 | 3 | Pseudomonas yamanorum | species | Increases |
| 0 | 3 | Pseudomonas extremaustralis | species | Increases |
| 0 | 3 | Pseudomonas psychrotolerans | species | Increases |
| 0 | 3 | [Flavobacterium] lutescens | species | Increases |
| 0 | 3 | Candidatus Pseudomonas adelgestsugas | species | Increases |
| 0 | 3 | Pseudomonas abietaniphila | species | Increases |
| 0 | 3 | Pseudomonas agarici | species | Increases |
| 0 | 3 | Pseudomonas alcaliphila | species | Increases |
| 0 | 3 | Pseudomonas alkylphenolica | species | Increases |
| 0 | 3 | Pseudomonas allokribbensis | species | Increases |
| 0 | 3 | Pseudomonas alvandae | species | Increases |
| 0 | 3 | Pseudomonas antarctica | species | Increases |
| 0 | 3 | Pseudomonas anuradhapurensis | species | Increases |
| 0 | 3 | Pseudomonas argentinensis | species | Increases |
| 0 | 3 | Pseudomonas arsenicoxydans | species | Increases |
| 0 | 3 | Pseudomonas asgharzadehiana | species | Increases |
| 0 | 3 | Pseudomonas asiatica | species | Increases |
| 0 | 3 | Pseudomonas asplenii | species | Increases |
| 0 | 3 | Pseudomonas atacamensis | species | Increases |
| 0 | 3 | Pseudomonas benzenivorans | species | Increases |
| 0 | 3 | Pseudomonas bijieensis | species | Increases |
| 0 | 3 | Pseudomonas brassicacearum | species | Increases |
| 0 | 3 | Pseudomonas campi | species | Increases |
| 0 | 3 | Pseudomonas canavaninivorans | species | Increases |
| 0 | 3 | Pseudomonas cavernae | species | Increases |
| 0 | 3 | Pseudomonas cerasi | species | Increases |
| 0 | 3 | Pseudomonas cinnamophila | species | Increases |
| 0 | 3 | Pseudomonas clemancea | species | Increases |
| 0 | 3 | Pseudomonas collierea | species | Increases |
| 0 | 3 | Pseudomonas cremoricolorata | species | Increases |
| 0 | 3 | Pseudomonas deceptionensis | species | Increases |
| 0 | 3 | Pseudomonas donghuensis | species | Increases |
| 0 | 3 | Pseudomonas entomophila | species | Increases |
| 0 | 3 | Pseudomonas eucalypticola | species | Increases |
| 0 | 3 | Pseudomonas fakonensis | species | Increases |
| 0 | 3 | Pseudomonas fitomaticsae | species | Increases |
| 0 | 3 | Pseudomonas flexibilis | species | Increases |
| 0 | 3 | Pseudomonas frederiksbergensis | species | Increases |
| 0 | 3 | Pseudomonas fulva | species | Increases |
| 0 | 3 | Pseudomonas gingeri | species | Increases |
| 0 | 3 | Pseudomonas glycinae | species | Increases |
| 0 | 3 | Pseudomonas gozinkensis | species | Increases |
| 0 | 3 | Pseudomonas graminis | species | Increases |
| 0 | 3 | Pseudomonas guangdongensis | species | Increases |
| 0 | 3 | Pseudomonas guguanensis | species | Increases |
| 0 | 3 | Pseudomonas guineae | species | Increases |
| 0 | 3 | Pseudomonas hamedanensis | species | Increases |
| 0 | 3 | Pseudomonas helleri | species | Increases |
| 0 | 3 | Pseudomonas humi | species | Increases |
| 0 | 3 | Pseudomonas hydrolytica | species | Increases |
| 0 | 3 | Pseudomonas hygromyciniae | species | Increases |
| 0 | 3 | Pseudomonas indoloxydans | species | Increases |
| 0 | 3 | Pseudomonas insulae | species | Increases |
| 0 | 3 | Pseudomonas izuensis | species | Increases |
| 0 | 3 | Pseudomonas japonica | species | Increases |
| 0 | 3 | Pseudomonas jessenii | species | Increases |
| 0 | 3 | Pseudomonas juntendi | species | Increases |
| 0 | 3 | Pseudomonas kermanshahensis | species | Increases |
| 0 | 3 | Pseudomonas khazarica | species | Increases |
| 0 | 3 | Pseudomonas kielensis | species | Increases |
| 0 | 3 | Pseudomonas knackmussii | species | Increases |
| 0 | 3 | Pseudomonas kribbensis | species | Increases |
| 0 | 3 | Pseudomonas lalkuanensis | species | Increases |
| 0 | 3 | Pseudomonas laurylsulfatiphila | species | Increases |
| 0 | 3 | Pseudomonas lini | species | Increases |
| 0 | 3 | Pseudomonas lurida | species | Increases |
| 0 | 3 | Pseudomonas lutea | species | Increases |
| 0 | 3 | Pseudomonas luteola | species | Increases |
| 0 | 3 | Pseudomonas marincola | species | Increases |
| 0 | 3 | Pseudomonas massiliensis | species | Increases |
| 0 | 3 | Pseudomonas metavorans | species | Increases |
| 0 | 3 | Pseudomonas monsensis | species | Increases |
| 0 | 3 | Pseudomonas monteilii | species | Increases |
| 0 | 3 | Pseudomonas mosselii | species | Increases |
| 0 | 3 | Pseudomonas muyukensis | species | Increases |
| 0 | 3 | Pseudomonas nitritireducens | species | Increases |
| 0 | 3 | Pseudomonas nunensis | species | Increases |
| 0 | 3 | Pseudomonas oryzae | species | Increases |
| 0 | 3 | Pseudomonas oryzihabitans | species | Increases |
| 0 | 3 | Pseudomonas otitidis | species | Increases |
| 0 | 3 | Pseudomonas palleroniana | species | Increases |
| 0 | 3 | Pseudomonas palmensis | species | Increases |
| 0 | 3 | Pseudomonas panacis | species | Increases |
| 0 | 3 | Pseudomonas panipatensis | species | Increases |
| 0 | 3 | Pseudomonas parafulva | species | Increases |
| 0 | 3 | Pseudomonas plecoglossicida | species | Increases |
| 0 | 3 | Pseudomonas pohangensis | species | Increases |
| 0 | 3 | Pseudomonas promysalinigenes | species | Increases |
| 0 | 3 | Pseudomonas prosekii | species | Increases |
| 0 | 3 | Pseudomonas qingdaonensis | species | Increases |
| 0 | 3 | Pseudomonas reidholzensis | species | Increases |
| 0 | 3 | Pseudomonas reinekei | species | Increases |
| 0 | 3 | Pseudomonas rhizophila | species | Increases |
| 0 | 3 | Pseudomonas rhizosphaerae | species | Increases |
| 0 | 3 | Pseudomonas saudimassiliensis | species | Increases |
| 0 | 3 | Pseudomonas saudiphocaensis | species | Increases |
| 0 | 3 | Pseudomonas sediminis | species | Increases |
| 0 | 3 | Pseudomonas seleniipraecipitans | species | Increases |
| 0 | 3 | Pseudomonas shirazica | species | Increases |
| 0 | 3 | Pseudomonas sichuanensis | species | Increases |
| 0 | 3 | Pseudomonas sihuiensis | species | Increases |
| 0 | 3 | Pseudomonas silesiensis | species | Increases |
| 0 | 3 | Pseudomonas siliginis | species | Increases |
| 0 | 3 | Pseudomonas simiae | species | Increases |
| 0 | 3 | Pseudomonas soli | species | Increases |
| 0 | 3 | Pseudomonas sp. R2A2 | species | Increases |
| 0 | 3 | Pseudomonas sp. SGAir0191 | species | Increases |
| 0 | 3 | Pseudomonas syncyanea | species | Increases |
| 0 | 3 | Pseudomonas taetrolens | species | Increases |
| 0 | 3 | Pseudomonas teessidea | species | Increases |
| 0 | 3 | Pseudomonas tensinigenes | species | Increases |
| 0 | 3 | Pseudomonas thermotolerans | species | Increases |
| 0 | 3 | Pseudomonas thivervalensis | species | Increases |
| 0 | 3 | Pseudomonas tohonis | species | Increases |
| 0 | 3 | Pseudomonas toyotomiensis | species | Increases |
| 0 | 3 | Pseudomonas tritici | species | Increases |
| 0 | 3 | Pseudomonas tropicalis | species | Increases |
| 0 | 3 | Pseudomonas tructae | species | Increases |
| 0 | 3 | Pseudomonas umsongensis | species | Increases |
| 0 | 3 | Pseudomonas uvaldensis | species | Increases |
| 0 | 3 | Pseudomonas vancouverensis | species | Increases |
| 0 | 3 | Pseudomonas vanderleydeniana | species | Increases |
| 0 | 3 | Pseudomonas versuta | species | Increases |
| 0 | 3 | Pseudomonas viciae | species | Increases |
| 0 | 3 | Pseudomonas wadenswilerensis | species | Increases |
| 0 | 3 | Pseudomonas wenzhouensis | species | Increases |
| 0 | 3 | Pseudomonas xantholysinigenes | species | Increases |
| 0 | 3 | Pseudomonas xanthosomatis | species | Increases |
| 0 | 3 | Pseudomonas zarinae | species | Increases |
| 0 | 3 | Pseudomonas zeae | species | Increases |
| 3 | 0 | Pseudomonas putida | species | Increases |
| 0 | 3 | Pseudomonas aeruginosa group | species group | Increases |
| 0 | 3 | Pseudomonas chlororaphis group | species group | Increases |
| 0 | 3 | Pseudomonas fluorescens group | species group | Increases |
| 0 | 3 | Pseudomonas syringae group | species group | Increases |
| 3 | 0 | Pseudomonas putida group | species group | Increases |
| 0 | 3 | Pseudomonas putida HB3267 | strain | Increases |
| 0 | 3 | Pseudomonas putida ND6 | strain | Increases |
| 0 | 3 | Pseudomonas putida S13.1.2 | strain | Increases |
| 0 | 3 | Pseudomonas putida W619 | strain | Increases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergic Rhinitis (Hay Fever) | 0.6 | 0.6 | |
| Allergies | 0.3 | 0.3 | |
| Alopecia (Hair Loss) | 0.5 | 0.6 | -0.2 |
| Alzheimer's disease | 0.5 | 0.6 | -0.2 |
| Autism | 0.6 | 0.6 | |
| Biofilm | 1.2 | -1.2 | |
| Bipolar Disorder | 0.6 | 0.6 | |
| Chronic Fatigue Syndrome | 0.9 | -0.9 | |
| Chronic Kidney Disease | 0.3 | -0.3 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.6 | -0.6 | |
| Colorectal Cancer | 0.6 | -0.6 | |
| Constipation | 0.6 | -0.6 | |
| COVID-19 | 0.6 | -0.6 | |
| Crohn's Disease | 0.6 | 0.6 | 0 |
| cystic fibrosis | 0.9 | -0.9 | |
| Denture Wearers Oral Shifts | 0.6 | 0.6 | 0 |
| Endometriosis | 0.6 | -0.6 | |
| Hidradenitis Suppurativa | 0.6 | -0.6 | |
| Hypothyroidism | 0.6 | -0.6 | |
| IgA nephropathy (IgAN) | 0.5 | 0.5 | |
| Inflammatory Bowel Disease | 0.6 | -0.6 | |
| Irritable Bowel Syndrome | 0.9 | -0.9 | |
| ME/CFS without IBS | 0.9 | -0.9 | |
| Mood Disorders | 0.9 | 0.9 | |
| Multiple Sclerosis | 0.6 | -0.6 | |
| obsessive-compulsive disorder | 0.6 | 0.6 | |
| pancreatic cancer | 0.5 | -0.5 | |
| Parkinson's Disease | 0.5 | 0.5 | |
| primary biliary cholangitis | 0.3 | 0.6 | -1 |
| Primary sclerosing cholangitis | 0.3 | 0.3 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.9 | -0.9 | |
| Schizophrenia | 0.3 | 0.3 | |
| Stress / posttraumatic stress disorder | 0.5 | 0.5 | |
| Systemic Lupus Erythematosus | 0.6 | 0.6 | |
| Ulcerative colitis | 0.6 | 0.6 |
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