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Digestive Health: NSPs play a crucial role in maintaining digestive health by promoting bowel regularity, preventing constipation, and supporting overall gut function. The fermentation of NSPs by gut bacteria produces short-chain fatty acids (SCFAs), which provide energy for colon cells and help maintain a healthy gut environment. Additionally, NSPs add bulk to stool, soften it, and increase fecal bulk, which promotes regularity and prevents constipation.
Blood Sugar Control: Soluble NSPs, such as pectins, gums, and mucilages, can slow down the absorption of glucose from the digestive tract into the bloodstream. This helps regulate blood sugar levels, preventing rapid spikes and crashes in blood glucose after meals. By improving glycemic control, NSPs may help reduce the risk of insulin resistance, type 2 diabetes, and metabolic syndrome.
Weight Management: NSPs contribute to feelings of fullness and satiety when consumed as part of a meal or snack. By increasing the bulk and viscosity of food in the digestive tract, NSPs can delay gastric emptying and promote satiety, leading to reduced hunger and calorie intake. Including NSP-rich foods in the diet may aid in weight management by promoting a lower energy intake and supporting healthy weight loss.
Cholesterol Levels: Some NSPs, particularly soluble fibers like beta-glucans, psyllium, and oat bran, have cholesterol-lowering effects. These fibers bind to bile acids in the digestive tract and promote their excretion, leading to a reduction in LDL cholesterol levels. Consuming NSP-rich foods or supplements may help improve lipid profiles and reduce the risk of cardiovascular disease.
Gut Microbiota Composition: NSPs serve as a substrate for beneficial bacteria in the colon, promoting the growth and activity of these microbes. By nourishing the gut microbiota, NSPs support a diverse and balanced microbial community, which is essential for optimal gut health and immune function. A healthy gut microbiota is associated with reduced inflammation, improved digestion, and enhanced immune response.
Rank | Probiotic | Impact |
---|---|---|
genus | Bifidobacterium | Increases |
order | Micrococcales | Increases |
species | Akkermansia muciniphila | Increases |
species | Bacteroides uniformis | Increases |
species | Bifidobacterium adolescentis | Increases |
species | Bifidobacterium animalis | Increases |
species | Bifidobacterium bifidum | Increases |
species | Bifidobacterium breve | Increases |
species | Bifidobacterium catenulatum | Increases |
species | Bifidobacterium longum | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
3 | 0 | Bacteroides | genus | Increases |
2 | 0 | Enterobacteriaceae | family | Increases |
2 | 0 | Prevotellaceae | family | Increases |
2 | 0 | Lactobacillus | genus | Increases |
2 | 0 | Prevotella | genus | Increases |
2 | 0 | Salmonella enterica subsp. enterica serovar Typhi | no rank | Decreases |
2 | 0 | Actinomycetota | phylum | Increases |
1 | 2 | Bacteroidaceae | family | Increases |
1 | 1 | Actinomycetes | class | Increases |
1 | 1 | Lachnospiraceae | family | Increases |
1 | 1 | Clostridium | genus | Increases |
1 | 1 | Roseburia | genus | Increases |
1 | 1 | Clostridium perfringens | species | Decreases |
1 | 1 | Phocaeicola vulgatus | species | Increases |
1 | 0 | Bacilli | class | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.7 | -0.7 | |
Acne | 3.5 | 2.8 | 0.25 |
ADHD | 3.9 | 7.3 | -0.87 |
Age-Related Macular Degeneration and Glaucoma | 0.7 | 0.8 | -0.14 |
Allergic Rhinitis (Hay Fever) | 6.5 | 4.5 | 0.44 |
Allergies | 11 | 12 | -0.09 |
Allergy to milk products | 3.1 | 6.1 | -0.97 |
Alopecia (Hair Loss) | 1.3 | 2.5 | -0.92 |
Alzheimer's disease | 12.4 | 13.4 | -0.08 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2.2 | 8.5 | -2.86 |
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