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🍽️ Citrus polymethoxyflavone {Nobiletin (oranges and lemons)}

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  1. Antioxidant Activity: Nobiletin exhibits strong antioxidant properties, meaning it can neutralize harmful free radicals in the body. Free radicals are unstable molecules that can damage cells and contribute to aging and various diseases. By scavenging free radicals, nobiletin helps to protect cells from oxidative stress and reduce the risk of oxidative damage to tissues throughout the body.

  2. Anti-inflammatory Effects: Nobiletin has been shown to possess anti-inflammatory properties, meaning it can reduce inflammation in the body. Chronic inflammation is associated with the development and progression of various diseases, including cardiovascular disease, neurodegenerative diseases, and cancer. By inhibiting inflammatory pathways and reducing the production of inflammatory molecules, nobiletin may help to alleviate symptoms and slow the progression of these diseases.

  3. Cardiovascular Health: Nobiletin may have beneficial effects on cardiovascular health. It helps to improve endothelial function, reduce inflammation in blood vessels, and inhibit the formation of blood clots. Nobiletin may also help to lower cholesterol levels and blood pressure, reducing the risk of cardiovascular diseases such as atherosclerosis, hypertension, and heart disease.

  4. Metabolic Health: Nobiletin has been studied for its potential benefits in improving metabolic health and preventing obesity and type 2 diabetes. It helps to regulate glucose metabolism, improve insulin sensitivity, and reduce lipid accumulation in adipose tissue and the liver. Nobiletin may also help to suppress appetite and promote weight loss.

  5. Neuroprotective Effects: Nobiletin has been investigated for its potential neuroprotective effects in the brain. It helps to protect neurons from oxidative damage, reduce inflammation, and modulate signaling pathways involved in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Nobiletin may also help to improve cognitive function and memory.

  6. Cancer Prevention: Nobiletin has been studied for its potential anti-cancer properties. It helps to inhibit the growth of cancer cells, induce apoptosis (programmed cell death), and prevent the spread of cancerous tumors. Nobiletin may also help to reduce the risk of cancer by modulating signaling pathways involved in cell growth, proliferation, and survival. It has been studied in various types of cancer, including breast, prostate, lung, colon, and skin cancer.

  7. Liver Health: Nobiletin has been shown to have hepatoprotective effects, meaning it can protect the liver from damage caused by toxins, alcohol, and other harmful substances. It helps to improve liver function, reduce inflammation, and promote liver regeneration. Nobiletin may also help to prevent or alleviate liver diseases such as fatty liver disease, hepatitis, and liver fibrosis.

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Data Contradictions — Limits of Certainity

Impacted of Citrus polymethoxyflavone {Nobiletin (oranges and lemons)} On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Increases
species Akkermansia muciniphila Increases
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Increases
species Bifidobacterium animalis Increases
species Bifidobacterium bifidum Increases
species Bifidobacterium breve Increases
species Bifidobacterium catenulatum Increases
species Bifidobacterium longum Increases
species Bifidobacterium pseudocatenulatum Increases
species Bifidobacterium pseudolongum Increases
species Lactobacillus acidophilus Increases
species Lactobacillus crispatus Increases
species Lactobacillus gasseri Increases
species Lactobacillus helveticus Increases
species Lactobacillus jensenii Increases
species Lactobacillus johnsonii Increases
species Lactobacillus kefiranofaciens Increases
species Ligilactobacillus salivarius Increases
species Limosilactobacillus reuteri Increases

Bacteria Impacted by Citrus polymethoxyflavone {Nobiletin (oranges and lemons)}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

🧙?

📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
1 0 Oscillospiraceae family Decreases
0 1 Bacteroidaceae family Decreases
0 1 Desulfovibrionaceae family Decreases
0 3 Bifidobacteriaceae family Increases
0 1 Erysipelotrichaceae family Increases
0 2 Lactobacillaceae family Increases
1 1 Lachnospiraceae family Increases
1 1 Akkermansiaceae family Increases
0 1 Faecalibacterium genus Decreases
1 0 Bacteroides genus Decreases
1 0 Desulfovibrio genus Decreases
1 0 Intestinimonas genus Decreases
1 0 Oscillibacter genus Decreases
1 0 Ruminiclostridium genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Vescimonas genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Acetanaerobacterium genus Decreases
0 1 Agathobaculum genus Decreases
0 1 Amygdalobacter genus Decreases
0 1 Anaerobacterium genus Decreases
0 1 Anaerofilum genus Decreases
0 1 Anaeromassilibacillus genus Decreases
0 1 Angelakisella genus Decreases
0 1 Bittarella (ex Durand et al. 2017) genus Decreases
0 1 Cellulosibacter genus Decreases
0 1 Congzhengia genus Decreases
0 1 Drancourtella genus Decreases
0 1 Ercella genus Decreases
0 1 Fournierella genus Decreases
0 1 Fumia genus Decreases
0 1 Gorbachella genus Decreases
0 1 Harryflintia genus Decreases
0 1 Hominenteromicrobium genus Decreases
0 1 Hominicoprocola genus Decreases
0 1 Hominilimicola genus Decreases
0 1 Hydrogeniiclostridium genus Decreases
0 1 Hydrogenoanaerobacterium genus Decreases
0 1 Ligaoa genus Decreases
0 1 Marasmitruncus genus Decreases
0 1 Marseillibacter genus Decreases
0 1 Massiliimalia genus Decreases
0 1 Merdimmobilis genus Decreases
0 1 Neglectibacter genus Decreases
0 1 Neobittarella genus Decreases
0 1 Oscillospira genus Decreases
0 1 Papillibacter genus Decreases
0 1 Provencibacterium genus Decreases
0 1 Pseudobacteroides genus Decreases
0 1 Pseudoflavonifractor genus Decreases
0 1 Pseudoruminococcus genus Decreases
0 1 Pygmaiobacter genus Decreases
0 1 Ructibacterium genus Decreases
0 1 Saccharofermentans genus Decreases
0 1 Shuzhengia genus Decreases
0 1 Sporobacter genus Decreases
0 1 Yanshouia genus Decreases
0 1 Youxingia genus Decreases
0 1 Anaerotruncus genus Decreases
0 1 Dysosmobacter genus Decreases
0 1 Lawsonibacter genus Decreases
0 1 Pusillibacter genus Decreases
0 1 Ruthenibacterium genus Decreases
0 1 Acetivibrio genus Decreases
0 1 Solibaculum genus Decreases
0 1 Monoglobus genus Decreases
0 1 Thermoclostridium genus Decreases
0 1 Acutalibacter genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Flavonifractor genus Decreases
0 1 Pseudoclostridium genus Decreases
0 1 Caproicibacter genus Decreases
0 1 Thermocaproicibacter genus Decreases
0 1 Caproiciproducens genus Decreases
0 1 Caproicibacterium genus Decreases
0 1 Ethanoligenens genus Decreases
0 1 Fastidiosipila genus Decreases
0 1 Petroclostridium genus Decreases
0 1 Anaerotignum genus Increases
0 1 Anaeropeptidivorans genus Increases
0 1 Anaeromicropila genus Increases
0 1 Chordicoccus genus Increases
0 1 Tyzzerella genus Increases
0 1 Anaerocolumna genus Increases
0 1 Enterocloster genus Increases
0 1 Pseudobutyrivibrio genus Increases
0 1 Sporofaciens genus Increases
0 1 Lachnospira genus Increases
0 1 Wujia genus Increases
0 1 Simiaoa genus Increases
0 1 Sellimonas genus Increases
0 1 Herbinix genus Increases
0 1 Qiania genus Increases
0 1 Lacrimispora genus Increases
0 1 Novisyntrophococcus genus Increases
0 1 Lachnoanaerobaculum genus Increases
0 1 Butyrivibrio genus Increases
0 1 Mediterraneibacter genus Increases
0 1 Lachnoclostridium genus Increases
0 1 Wansuia genus Increases
0 1 Acetatifactor genus Increases
0 1 Acetitomaculum genus Increases
0 1 Agathobacter genus Increases
0 1 Anaerobium genus Increases
0 1 Anaerosacchariphilus genus Increases
0 1 Anaerosporobacter genus Increases
0 1 Anaerotaenia genus Increases
0 1 Anthropogastromicrobium genus Increases
0 1 Bariatricus genus Increases
0 1 Brotaphodocola genus Increases
0 1 Butyribacter genus Increases
0 1 Candidatus Epulonipiscium genus Increases
0 1 Catenibacillus genus Increases
0 1 Catonella genus Increases
0 1 Claveliimonas genus Increases
0 1 Cuneatibacter genus Increases
0 1 Diplocloster genus Increases
0 1 Eisenbergiella genus Increases
0 1 Extibacter genus Increases
0 1 Faecalicatena genus Increases
0 1 Faecalimonas genus Increases
0 1 Frisingicoccus genus Increases
0 1 Fusicatenibacter genus Increases
0 1 Gallintestinimicrobium genus Increases
0 1 Gluceribacter genus Increases
0 1 Hespellia genus Increases
0 1 Hominifimenecus genus Increases
0 1 Hominisplanchenecus genus Increases
0 1 Hoministercoradaptatus genus Increases
0 1 Hominiventricola genus Increases
0 1 Jingyaoa genus Increases
0 1 Johnsonella genus Increases
0 1 Jutongia genus Increases
0 1 Kineothrix genus Increases
0 1 Lachnobacterium genus Increases
0 1 Lachnotalea genus Increases
0 1 Lientehia genus Increases
0 1 Limosilactobacillus genus Increases
0 1 Luxibacter genus Increases
0 1 Merdimonas genus Increases
0 1 Mobilitalea genus Increases
0 1 Moryella genus Increases
0 1 Muricomes genus Increases
0 1 Murimonas genus Increases
0 1 Niameybacter genus Increases
0 1 Oliverpabstia genus Increases
0 1 Oribacterium genus Increases
0 1 Parablautia genus Increases
0 1 Pararoseburia genus Increases
0 1 Parasporobacterium genus Increases
0 1 Porcincola genus Increases
0 1 Robinsoniella genus Increases
0 1 Sakamotonia genus Increases
0 1 Schaedlerella genus Increases
0 1 Shuttleworthella genus Increases
0 1 Sporobacterium genus Increases
0 1 Stomatobaculum genus Increases
0 1 Suonthocola genus Increases
0 1 Syntrophococcus genus Increases
0 1 Waltera genus Increases
0 1 Zhenhengia genus Increases
0 1 Marvinbryantia genus Increases
0 1 Coprococcus genus Increases
0 1 Anaerostipes genus Increases
0 1 Dorea genus Increases
0 1 Anaerobutyricum genus Increases
0 1 Blautia genus Increases
1 0 Allobaculum genus Increases
1 0 Ligilactobacillus genus Increases
1 1 Roseburia genus Increases
1 1 Akkermansia genus Increases
2 0 Lactobacillus genus Increases
3 0 Bifidobacterium genus Increases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 Eubacteriales incertae sedis no rank Decreases
0 1 Oscillospiraceae incertae sedis no rank Decreases
0 1 unclassified Bacteroides no rank Decreases
0 1 unclassified Desulfovibrio no rank Decreases
0 1 unclassified Intestinimonas no rank Decreases
0 1 unclassified Oscillibacter no rank Decreases
0 1 unclassified Oscillospiraceae no rank Decreases
0 1 unclassified Ruminiclostridium no rank Decreases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 Lachnospiraceae incertae sedis no rank Increases
0 1 unclassified Akkermansia no rank Increases
0 1 unclassified Allobaculum no rank Increases
0 1 unclassified Lachnospiraceae no rank Increases
0 1 unclassified Ligilactobacillus no rank Increases
0 1 unclassified Roseburia no rank Increases
0 2 environmental samples no rank Increases
0 2 unclassified Lactobacillus no rank Increases
0 3 environmental samples no rank Increases
0 3 unclassified Bifidobacterium no rank Increases
0 2 Eubacteriales order Decreases
0 1 Verrucomicrobiales order Increases
0 1 Bacteroides togonis QST454 Decreases
0 1 Bacteroides bouchesdurhonensis QSV445 Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Ruminiclostridium cellulolyticum species Decreases
0 1 Ruminiclostridium papyrosolvens species Decreases
0 1 Desulfovibrio piger species Decreases
0 1 Bacteroides acidifaciens species Decreases
0 1 Bacteroides caecigallinarum species Decreases
0 1 Bacteroides clarus species Decreases
0 1 Bacteroides congonensis species Decreases
0 1 Bacteroides cutis species Decreases
0 1 Bacteroides denticanum species Decreases
0 1 Bacteroides difficilis species Decreases
0 1 Bacteroides faecalis species Decreases
0 1 Bacteroides faecichinchillae species Decreases
0 1 Bacteroides finegoldii species Decreases
0 1 Bacteroides fluxus species Decreases
0 1 Bacteroides galacturonicus species Decreases
0 1 Bacteroides gallinaceum species Decreases
0 1 Bacteroides gallinarum species Decreases
0 1 Bacteroides graminisolvens species Decreases
0 1 Bacteroides ihuae species Decreases
0 1 Bacteroides ilei species Decreases
0 1 Bacteroides koreensis species Decreases
0 1 Bacteroides kribbi species Decreases
0 1 Bacteroides luti species Decreases
0 1 Bacteroides mediterraneensis species Decreases
0 1 Bacteroides muris (ex Fokt et al. 2023) species Decreases
0 1 Bacteroides ndongoniae species Decreases
0 1 Bacteroides oleiciplenus species Decreases
0 1 Bacteroides parvus species Decreases
0 1 Bacteroides propionicifaciens species Decreases
0 1 Bacteroides propionicigenes species Decreases
0 1 Bacteroides pyogenes species Decreases
0 1 Bacteroides reticulotermitis species Decreases
0 1 Bacteroides rhinocerotis species Decreases
0 1 Bacteroides rodentium species Decreases
0 1 Bacteroides stercorirosoris species Decreases
0 1 Bacteroides timonensis species Decreases
0 1 Candidatus Bacteroides intestinigallinarum species Decreases
0 1 Candidatus Desulfovibrio faecigallinarum species Decreases
0 1 Candidatus Intestinimonas pullistercoris species Decreases
0 1 Candidatus Intestinimonas stercoravium species Decreases
0 1 Candidatus Intestinimonas stercorigallinarum species Decreases
0 1 Candidatus Oscillibacter avistercoris species Decreases
0 1 Candidatus Oscillibacter excrementavium species Decreases
0 1 Candidatus Oscillibacter pullicola species Decreases
0 1 Desulfovibrio aminophilus species Decreases
0 1 Desulfovibrio biadhensis species Decreases
0 1 Desulfovibrio caledoniensis species Decreases
0 1 Desulfovibrio cuneatus species Decreases
0 1 Desulfovibrio diazotrophicus species Decreases
0 1 Desulfovibrio ferrophilus species Decreases
0 1 Desulfovibrio giganteus species Decreases
0 1 Desulfovibrio inopinatus species Decreases
0 1 Desulfovibrio intestinalis species Decreases
0 1 Desulfovibrio lacusfryxellense species Decreases
0 1 Desulfovibrio legallii species Decreases
0 1 Desulfovibrio litoralis species Decreases
0 1 Desulfovibrio longreachensis species Decreases
0 1 Desulfovibrio mangrovi species Decreases
0 1 Desulfovibrio oryzae species Decreases
0 1 Desulfovibrio oviles species Decreases
0 1 Desulfovibrio oxyclinae species Decreases
0 1 Desulfovibrio porci species Decreases
0 1 Desulfovibrio psychrotolerans species Decreases
0 1 Desulfovibrio simplex species Decreases
0 1 Desulfovibrio subterraneus species Decreases
0 1 Intestinimonas aquisgranensis species Decreases
0 1 Intestinimonas gabonensis species Decreases
0 1 Intestinimonas massiliensis (ex Afouda et al. 2020) species Decreases
0 1 Intestinimonas timonensis species Decreases
0 1 Oscillibacter acetigenes species Decreases
0 1 Oscillibacter massiliensis species Decreases
0 1 Oscillibacter ruminantium species Decreases
0 1 Oscillibacter valericigenes species Decreases
0 1 Ruminiclostridium cellobioparum species Decreases
0 1 Ruminiclostridium hungatei species Decreases
0 1 Ruminiclostridium josui species Decreases
0 1 Ruminiclostridium sufflavum species Decreases
0 1 Bacteroides ovatus species Decreases
0 1 Bacteroides uniformis species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Bacteroides fragilis species Decreases
0 1 Bacteroides xylanisolvens species Decreases
0 1 Bacteroides thetaiotaomicron species Decreases
0 1 Bacteroides caecimuris species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Bacteroides faecium species Decreases
0 1 Desulfovibrio fairfieldensis species Decreases
0 1 Ruminiclostridium herbifermentans species Decreases
0 1 Bacteroides salyersiae species Decreases
0 1 Bacteroides faecis species Decreases
0 1 Bacteroides helcogenes species Decreases
0 1 Desulfovibrio desulfuricans species Decreases
0 1 Bacteroides eggerthii species Decreases
0 1 Nitratidesulfovibrio vulgaris species Decreases
0 1 Bacteroides caccae species Decreases
0 1 Bacteroides intestinalis species Decreases
0 1 Bacteroides cellulosilyticus species Decreases
0 1 Bacteroides stercoris species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Bacteroides zhangwenhongii species Decreases
0 1 Candidatus Desulfovibrio trichonymphae species Decreases
0 1 Bacteroides heparinolyticus species Decreases
0 1 Bacteroides coprosuis species Decreases
0 1 Bacteroides zoogleoformans species Decreases
0 3 Bifidobacterium saguini species Increases
0 2 Lactobacillus ultunensis species Increases
0 3 Bifidobacterium pseudolongum species Increases
0 3 Bifidobacterium asteroides species Increases
0 3 Bifidobacterium subtile species Increases
0 3 Bifidobacterium pullorum species Increases
0 1 Akkermansia glycaniphila species Increases
0 3 Bifidobacterium animalis species Increases
0 1 Ligilactobacillus murinus species Increases
0 3 Bifidobacterium scardovii species Increases
0 3 Bifidobacterium imperatoris species Increases
0 3 Bifidobacterium thermophilum species Increases
0 1 Ligilactobacillus agilis species Increases
0 3 Bifidobacterium lemurum species Increases
0 2 Lactobacillus helveticus species Increases
0 3 Bifidobacterium eulemuris species Increases
0 2 Lactobacillus johnsonii species Increases
0 2 Lactobacillus kefiranofaciens species Increases
0 1 Ligilactobacillus salivarius species Increases
0 1 Ligilactobacillus animalis species Increases
0 2 Lactobacillus amylolyticus species Increases
0 3 Bifidobacterium dentium species Increases
0 1 Ligilactobacillus saerimneri species Increases
0 3 Bifidobacterium choerinum species Increases
0 2 Lactobacillus acetotolerans species Increases
0 1 Allobaculum mucilyticum species Increases
0 2 Lactobacillus amylovorus species Increases
0 2 Lactobacillus iners species Increases
0 2 Lactobacillus taiwanensis species Increases
0 1 Akkermansia massiliensis species Increases
0 1 Allobaculum stercoricanis species Increases
0 1 Bifidobacterium stercoris species Increases
0 1 Candidatus Akkermansia intestinavium species Increases
0 1 Ligilactobacillus acidipiscis species Increases
0 1 Ligilactobacillus apodemi species Increases
0 1 Ligilactobacillus araffinosus species Increases
0 1 Ligilactobacillus aviarius species Increases
0 1 Ligilactobacillus ceti species Increases
0 1 Ligilactobacillus equi species Increases
0 1 Ligilactobacillus faecis species Increases
0 1 Ligilactobacillus hayakitensis species Increases
0 1 Ligilactobacillus pobuzihii species Increases
0 1 Roseburia cecicola species Increases
0 1 Roseburia difficilis species Increases
0 1 Roseburia faecis species Increases
0 1 Roseburia inulinivorans species Increases
0 1 Roseburia lenta species Increases
0 1 Roseburia porci species Increases
0 1 Roseburia yibonii species Increases
0 1 Roseburia zhanii species Increases
0 2 Lactobacillus crispatus species Increases
0 2 Lactobacillus intestinalis species Increases
0 3 Bifidobacterium pseudocatenulatum species Increases
0 1 Roseburia hominis species Increases
0 2 Lactobacillus acidophilus species Increases
0 1 Roseburia rectibacter species Increases
0 2 Lactobacillus paragasseri species Increases
0 2 Lactobacillus jensenii species Increases
0 1 Ligilactobacillus ruminis species Increases
0 2 Lactobacillus gasseri species Increases
0 1 Roseburia intestinalis species Increases
0 2 [Lactobacillus] rogosae species Increases
0 2 Lactobacillus alvei species Increases
0 2 Lactobacillus animata species Increases
0 2 Lactobacillus apis species Increases
0 2 Lactobacillus bombicola species Increases
0 2 Lactobacillus brevisimilis species Increases
0 2 Lactobacillus equicursoris species Increases
0 2 Lactobacillus faeni species Increases
0 2 Lactobacillus fornicalis species Increases
0 2 Lactobacillus gallinarum species Increases
0 2 Lactobacillus gigeriorum species Increases
0 2 Lactobacillus guizhouensis species Increases
0 2 Lactobacillus hamsteri species Increases
0 2 Lactobacillus helsingborgensis species Increases
0 2 Lactobacillus hominis species Increases
0 2 Lactobacillus intermedius species Increases
0 2 Lactobacillus japonicus species Increases
0 2 Lactobacillus kalixensis species Increases
0 2 Lactobacillus kitasatonis species Increases
0 2 Lactobacillus kullabergensis species Increases
0 2 Lactobacillus leichmannii species Increases
0 2 Lactobacillus letivazi species Increases
0 2 Lactobacillus mulieris species Increases
0 2 Lactobacillus panisapium species Increases
0 2 Lactobacillus pasteurii species Increases
0 2 Lactobacillus psittaci species Increases
0 2 Lactobacillus rodentium species Increases
0 2 Lactobacillus selangorensis species Increases
0 2 Lactobacillus terrae species Increases
0 1 Akkermansia muciniphila species Increases
0 2 Lactobacillus delbrueckii species Increases
0 3 Bifidobacterium angulatum species Increases
1 0 Limosilactobacillus reuteri species Increases
0 3 Bifidobacterium bifidum species Increases
0 3 Bifidobacterium adolescentis species Increases
0 3 Bifidobacterium catenulatum species Increases
0 3 Bifidobacterium actinocoloniiforme species Increases
0 3 Bifidobacterium aesculapii species Increases
0 3 Bifidobacterium avesanii species Increases
0 3 Bifidobacterium biavatii species Increases
0 3 Bifidobacterium bohemicum species Increases
0 3 Bifidobacterium bombi species Increases
0 3 Bifidobacterium boum species Increases
0 3 Bifidobacterium callitrichidarum species Increases
0 3 Bifidobacterium callitrichos species Increases
0 3 Bifidobacterium commune species Increases
0 3 Bifidobacterium coryneforme species Increases
0 3 Bifidobacterium cuniculi species Increases
0 3 Bifidobacterium faecale species Increases
0 3 Bifidobacterium gallicum species Increases
0 3 Bifidobacterium indicum species Increases
0 3 Bifidobacterium magnum species Increases
0 3 Bifidobacterium merycicum species Increases
0 3 Bifidobacterium minimum species Increases
0 3 Bifidobacterium mongoliense species Increases
0 3 Bifidobacterium moukalabense species Increases
0 3 Bifidobacterium myosotis species Increases
0 3 Bifidobacterium porcinum species Increases
0 3 Bifidobacterium psychraerophilum species Increases
0 3 Bifidobacterium reuteri species Increases
0 3 Bifidobacterium ruminantium species Increases
0 3 Bifidobacterium simiae species Increases
0 3 Bifidobacterium stellenboschense species Increases
0 3 Bifidobacterium thermacidophilum species Increases
0 3 Bifidobacterium tissieri species Increases
0 3 Bifidobacterium tsurumiense species Increases
0 3 Bifidobacterium breve species Increases
0 3 Bifidobacterium longum species Increases
0 2 Lactobacillus casei group species group Increases
0 1 Limosilactobacillus reuteri subsp. murium subspecies Increases
0 1 Limosilactobacillus reuteri subsp. reuteri subspecies Increases
0 1 Limosilactobacillus reuteri subsp. rodentium subspecies Increases
0 1 Limosilactobacillus reuteri subsp. suis subspecies Increases

Impact of Citrus polymethoxyflavone {Nobiletin (oranges and lemons)} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2 0
Acne 3.5 0.3 10.67
ADHD 3.5 3.5 0
Age-Related Macular Degeneration and Glaucoma 0.4 1.3 -2.25
Allergic Rhinitis (Hay Fever) 3.8 3.1 0.23
Allergies 7.8 7.9 -0.01
Allergy to milk products 3.5 1.8 0.94
Alopecia (Hair Loss) 0.1 2.4 -23
Alzheimer's disease 9 10.2 -0.13
Amyotrophic lateral sclerosis (ALS) Motor Neuron 3.5 5.5 -0.57
Ankylosing spondylitis 4.5 4.5 0
Anorexia Nervosa 2.7 3 -0.11
Antiphospholipid syndrome (APS) 0.2 0.5 -1.5
Asthma 5.5 4.5 0.22
Atherosclerosis 3.1 2.2 0.41
Atrial fibrillation 3.1 5 -0.61
Autism 11.9 7.9 0.51
Autoimmune Disease 2.2 1.2 0.83
Barrett esophagus cancer 0 0
benign prostatic hyperplasia 0.3 1.5 -4
Biofilm 0.2 -0.2
Bipolar Disorder 3.1 1.1 1.82
Brain Trauma 2.6 2.4 0.08
Breast Cancer 2.2 -2.2
Cancer (General) 2.5 0.1 24
Carcinoma 3.2 3.8 -0.19
Celiac Disease 5.5 5 0.1
Cerebral Palsy 2.2 2.5 -0.14
Chronic Fatigue Syndrome 5.3 2.8 0.89
Chronic Kidney Disease 5.1 0.7 6.29
Chronic Lyme 0.4 0.5 -0.25
Chronic Obstructive Pulmonary Disease (COPD) 2.3 2.6 -0.13
Chronic Urticaria (Hives) 0.9 0.7 0.29
Coagulation / Micro clot triggering bacteria 2.1 0.6 2.5
Cognitive Function 4.5 3.8 0.18
Colorectal Cancer 5.7 7.8 -0.37
Constipation 2.5 1.1 1.27
Coronary artery disease 3.9 3 0.3
COVID-19 11.2 7.6 0.47
Crohn's Disease 9.4 8.9 0.06
Cushing's Syndrome (hypercortisolism) 0.5 -0.5
cystic fibrosis 1.7 1.5 0.13
d-lactic acidosis (one form of brain fog) 1.7 -1.7
deep vein thrombosis 2.1 3.5 -0.67
Denture Wearers Oral Shifts 0.7 0.3 1.33
Depression 15.2 11.6 0.31
Dermatomyositis 0.6 0.6 0
Eczema 2.5 0.3 7.33
Endometriosis 3.4 2.6 0.31
Eosinophilic Esophagitis
Epilepsy 5.3 3.7 0.43
erectile dysfunction 1.6 1.4 0.14
Fibromyalgia 2.9 3.9 -0.34
Functional constipation / chronic idiopathic constipation 6.6 5.4 0.22
gallstone disease (gsd) 3.8 1.8 1.11
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 2 0.3 5.67
Generalized anxiety disorder 4 3.2 0.25
giant cell arteritis 0.5 -0.5
Glioblastoma 0.8 1 -0.25
Gout 3.5 0.9 2.89
Graves' disease 4.3 2.6 0.65
Gulf War Syndrome 2.5 1.4 0.79
Halitosis 1.1 1.1
Hashimoto's thyroiditis 5 5 0
Heart Failure 5.8 3.8 0.53
hemorrhagic stroke 1.1 -1.1
Hemorrhoidal disease, Hemorrhoids, Piles 0.3 0.3
Hidradenitis Suppurativa 1.1 0.1 10
High Histamine/low DAO 0.9 1.9 -1.11
hypercholesterolemia (High Cholesterol) 1.2 1.1 0.09
hyperglycemia 3.9 2 0.95
Hyperlipidemia (High Blood Fats) 2.3 2.3 0
hypersomnia 1 0.5 1
hypertension (High Blood Pressure 8 9.1 -0.14
Hypothyroidism 4.3 2.7 0.59
Hypoxia 2.2 2.1 0.05
IgA nephropathy (IgAN) 3.2 1.7 0.88
Inflammatory Bowel Disease 9.8 5.3 0.85
Insomnia 3.9 5.8 -0.49
Intelligence 1.5 1.9 -0.27
Intracranial aneurysms 3.6 1.2 2
Irritable Bowel Syndrome 7.7 7.9 -0.03
ischemic stroke 3.1 4.6 -0.48
Liver Cirrhosis 7.4 7.2 0.03
Long COVID 9.3 9.6 -0.03
Low bone mineral density 1.3 1.3 0
Lung Cancer 2.1 0.8 1.63
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 1.7 0.3 4.67
ME/CFS with IBS 0.9 1 -0.11
ME/CFS without IBS 1.2 0.5 1.4
Menopause 2 1.7 0.18
Metabolic Syndrome 11.4 9.9 0.15
Mood Disorders 11 11.3 -0.03
multiple chemical sensitivity [MCS] 0.5 1.2 -1.4
Multiple Sclerosis 5.9 5.4 0.09
Multiple system atrophy (MSA) 1.1 2.5 -1.27
myasthenia gravis 1 1.3 -0.3
neuropathic pain 2.6 1.2 1.17
Neuropathy (all types) 0.9 2.6 -1.89
neuropsychiatric disorders (PANDAS, PANS) 0.8 0.5 0.6
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 9.2 6.6 0.39
NonCeliac Gluten Sensitivity 2.2 2.6 -0.18
Obesity 12.1 12.6 -0.04
obsessive-compulsive disorder 6.2 2.3 1.7
Osteoarthritis 2.3 2.5 -0.09
Osteoporosis 4.6 3.4 0.35
pancreatic cancer 1.4 0.5 1.8
Parkinson's Disease 10.5 8.3 0.27
Peanut Allergy 0.4 0.4
Polycystic ovary syndrome 7.4 6.1 0.21
Postural orthostatic tachycardia syndrome 0.9 0.3 2
Premenstrual dysphoric disorder 0.3 1.3 -3.33
primary biliary cholangitis 2.6 -2.6
Primary sclerosing cholangitis 2.3 1.9 0.21
Psoriasis 3.7 3.2 0.16
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 8.5 7.6 0.12
Rosacea 1.9 1 0.9
Schizophrenia 6.9 6.6 0.05
scoliosis 1 1.1 -0.1
sensorineural hearing loss 0.4 0.5 -0.25
Sjögren syndrome 2.9 2.3 0.26
Sleep Apnea 3.1 3.6 -0.16
Slow gastric motility / Gastroparesis 2 2
Small Intestinal Bacterial Overgrowth (SIBO) 2 1.2 0.67
Stress / posttraumatic stress disorder 2.9 4.4 -0.52
Systemic Lupus Erythematosus 5.2 3.4 0.53
Tic Disorder 2.6 2.6
Tourette syndrome 0.6 1.9 -2.17
Type 1 Diabetes 4.9 5.5 -0.12
Type 2 Diabetes 8.9 10 -0.12
Ulcerative colitis 8.4 7.4 0.14
Unhealthy Ageing 4.4 2.4 0.83
Vitiligo 2.5 1.5 0.67

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