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🍽️ glutathione

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  1. Antioxidant Activity: Glutathione is a potent antioxidant that helps to neutralize harmful free radicals in the body. Free radicals are unstable molecules that can damage cells and contribute to aging and various diseases. Glutathione acts as a first line of defense against oxidative stress, helping to protect cells from damage and maintain cellular integrity.

  2. Detoxification: Glutathione plays a crucial role in the detoxification process by binding to and neutralizing toxins, heavy metals, and other harmful substances in the body. It helps to facilitate the removal of these toxins from cells and tissues, promoting overall detoxification and reducing the risk of toxicity-related diseases.

  3. Immune Function: Glutathione supports immune function by enhancing the activity of immune cells, such as T cells and natural killer cells. It helps to regulate the immune response, modulate inflammation, and protect immune cells from oxidative damage. Adequate glutathione levels are essential for maintaining a healthy immune system and protecting against infections and diseases.

  4. Cellular Repair and Regeneration: Glutathione is involved in various cellular processes, including DNA synthesis, repair, and regeneration. It helps to maintain the integrity of cell membranes, proteins, and other cellular structures, promoting overall cell health and longevity. Glutathione also plays a role in cell signaling pathways that regulate cell growth, proliferation, and apoptosis (programmed cell death).

  5. Neurological Health: Glutathione has been studied for its potential neuroprotective effects in the brain. It helps to protect neurons from oxidative damage, reduce inflammation, and improve mitochondrial function. Glutathione levels are particularly high in the brain, where it plays a crucial role in maintaining neuronal health and function. Dysregulation of glutathione metabolism has been implicated in neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

  6. Respiratory Health: Glutathione has been investigated for its potential therapeutic role in respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. It helps to reduce inflammation in the airways, improve lung function, and protect against oxidative damage caused by environmental pollutants and cigarette smoke.

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Data Contradictions β€” Limits of Certainity

Impacted of glutathione On Probiotics

Rank Probiotic Impact
species Bacteroides uniformis Increases
species Escherichia coli Reduces

Bacteria Impacted by glutathione

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

πŸ§™?

πŸ““ Direct Citations πŸ‘ͺπŸ‘Ά Indirect Citations Taxonomy Rank Effect
0 2 Enterobacteriaceae family Decreases
0 1 Bacteroidaceae family Increases
0 1 Selenomonadaceae family Increases
0 1 Veillonellaceae family Increases
1 0 Escherichia genus Decreases
1 0 Plesiomonas genus Decreases
1 0 Shigella genus Decreases
1 0 Bacteroides genus Increases
1 0 Megamonas genus Increases
1 0 Megasphaera genus Increases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Escherichia no rank Decreases
0 1 unclassified Shigella no rank Decreases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 unclassified Bacteroides no rank Increases
0 1 unclassified Megamonas no rank Increases
0 1 unclassified Megasphaera no rank Increases
0 1 Plesiomonas shigelloides species Decreases
0 1 Escherichia coli species Decreases
0 1 Shigella flexneri species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella boydii species Decreases
0 1 Escherichia albertii species Decreases
0 1 Shigella sonnei species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Escherichia ruysiae species Decreases
0 1 Bacteroides zoogleoformans species Increases
0 1 Bacteroides coprosuis species Increases
0 1 Bacteroides heparinolyticus species Increases
0 1 Bacteroides zhangwenhongii species Increases
0 1 Bacteroides nordii species Increases
0 1 Bacteroides stercoris species Increases
0 1 Bacteroides cellulosilyticus species Increases
0 1 Bacteroides intestinalis species Increases
0 1 Bacteroides caccae species Increases
0 1 Bacteroides eggerthii species Increases
0 1 Bacteroides helcogenes species Increases
0 1 Bacteroides faecis species Increases
0 1 Bacteroides salyersiae species Increases
0 1 Bacteroides faecium species Increases
0 1 Bacteroides humanifaecis species Increases
0 1 Megasphaera massiliensis species Increases
0 1 Bacteroides caecimuris species Increases
0 1 Bacteroides thetaiotaomicron species Increases
0 1 Bacteroides xylanisolvens species Increases
0 1 Bacteroides fragilis species Increases
0 1 Bacteroides luhongzhouii species Increases
0 1 Bacteroides uniformis species Increases
0 1 Bacteroides ovatus species Increases
0 1 Megasphaera stantonii species Increases
0 1 Bacteroides acidifaciens species Increases
0 1 Bacteroides caecigallinarum species Increases
0 1 Bacteroides caecimuri species Increases
0 1 Bacteroides chinchillae species Increases
0 1 Bacteroides clarus species Increases
0 1 Bacteroides congonensis species Increases
0 1 Bacteroides cutis species Increases
0 1 Bacteroides denticanum species Increases
0 1 Bacteroides difficilis species Increases
0 1 Bacteroides faecalis species Increases
0 1 Bacteroides faecichinchillae species Increases
0 1 Bacteroides finegoldii species Increases
0 1 Bacteroides fluxus species Increases
0 1 Bacteroides galacturonicus species Increases
0 1 Bacteroides gallinaceum species Increases
0 1 Bacteroides gallinarum species Increases
0 1 Bacteroides graminisolvens species Increases
0 1 Bacteroides ihuae species Increases
0 1 Bacteroides ilei species Increases
0 1 Bacteroides koreensis species Increases
0 1 Bacteroides kribbi species Increases
0 1 Bacteroides luti species Increases
0 1 Bacteroides mediterraneensis species Increases
0 1 Bacteroides muris (ex Fokt et al. 2023) species Increases
0 1 Bacteroides ndongoniae species Increases
0 1 Bacteroides oleiciplenus species Increases
0 1 Bacteroides parvus species Increases
0 1 Bacteroides propionicifaciens species Increases
0 1 Bacteroides propionicigenes species Increases
0 1 Bacteroides pyogenes species Increases
0 1 Bacteroides reticulotermitis species Increases
0 1 Bacteroides rhinocerotis species Increases
0 1 Bacteroides rodentium species Increases
0 1 Bacteroides sp species Increases
0 1 Bacteroides sp. C13EG172 species Increases
0 1 Bacteroides stercorirosoris species Increases
0 1 Bacteroides timonensis species Increases
0 1 Candidatus Bacteroides intestinigallinarum species Increases
0 1 Megamonas rupellensis species Increases
0 1 Megasphaera butyrica species Increases
0 1 Megasphaera cerevisiae species Increases
0 1 Megasphaera genomosp. C1 species Increases
0 1 Megasphaera genomosp. type_1 species Increases
0 1 Megasphaera hominis species Increases
0 1 Megasphaera indica species Increases
0 1 Megasphaera lornae species Increases
0 1 Megasphaera micronuciformis species Increases
0 1 Megasphaera paucivorans species Increases
0 1 Megasphaera sueciensis species Increases
0 1 Megasphaera vaginalis (ex Bordigoni et al. 2020) species Increases
0 1 Megasphaera vaginalis (ex Srinivasan et al. 2021) species Increases
0 1 Megamonas hypermegale species Increases
0 1 Megasphaera hexanoica species Increases
0 1 Megasphaera elsdenii species Increases
0 1 Megamonas funiformis species Increases

Impact of glutathione on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 -0.2
Acne 0.9 -0.9
ADHD 0.6 1.6 -1.67
Allergic Rhinitis (Hay Fever) 0.5 1.2 -1.4
Allergies 3.1 0.5 5.2
Allergy to milk products 1.2 1.1 0.09
Alopecia (Hair Loss) 0.7 -0.7
Alzheimer's disease 1.8 2.8 -0.56
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.9 0.8 1.37
Ankylosing spondylitis 2.5 1.5 0.67
Anorexia Nervosa 0.8 0.8
Antiphospholipid syndrome (APS) 0.6 0.2 2
Asthma 1.2 2 -0.67
Atherosclerosis 0.6 0.8 -0.33
Atrial fibrillation 0.9 1.8 -1
Autism 2.7 4.2 -0.56
Autoimmune Disease 1 1
Barrett esophagus cancer 0.9 0.9
benign prostatic hyperplasia 1.6 1.6
Biofilm 0.6 0.6
Bipolar Disorder 1.6 0.6 1.67
Brain Trauma 0.6 0.6 0
Breast Cancer 0.6 0.6
Cancer (General) 0.1 0.1
Carcinoma 1.1 0.6 0.83
Celiac Disease 1.8 1.7 0.06
Cerebral Palsy 0.6 0.6 0
Chronic Fatigue Syndrome 1.2 1.3 -0.08
Chronic Kidney Disease 1 1.3 -0.3
Chronic Lyme 0.6 0.6
Chronic Obstructive Pulmonary Disease (COPD) 0.6 0.6 0
Chronic Urticaria (Hives) 1.3 1.3
Coagulation / Micro clot triggering bacteria 1.6 1.6
Cognitive Function 1.5 -1.5
Colorectal Cancer 3.3 2.9 0.14
Constipation 2.5 0.9 1.78
Coronary artery disease 2.4 2.4
COVID-19 3.7 1.6 1.31
Crohn's Disease 4.4 2.2 1
Cushing's Syndrome (hypercortisolism) 0.6 0.6
cystic fibrosis 1.7 1.7
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 2.2 0.2 10
Denture Wearers Oral Shifts 0.6 -0.6
Depression 3.5 4 -0.14
Eczema 2.1 0.3 6
Endometriosis 1.6 1.2 0.33
Epilepsy 2.8 2.3 0.22
erectile dysfunction 1.1 1.2 -0.09
Fibromyalgia 0.8 0.8
Functional constipation / chronic idiopathic constipation 3.9 1.9 1.05
gallstone disease (gsd) 1.1 0.2 4.5
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.2 -0.2
Generalized anxiety disorder 2.2 0.6 2.67
Gout 0 1.9 0
Graves' disease 1.8 1.2 0.5
Gulf War Syndrome 0.4 0.3 0.33
Halitosis 1.2 -1.2
Hashimoto's thyroiditis 1.2 0.8 0.5
Heart Failure 1.6 1.2 0.33
Hidradenitis Suppurativa 0.6 -0.6
High Histamine/low DAO 1.2 1.2
hypercholesterolemia (High Cholesterol) 0.6 0.6 0
hyperglycemia 2.2 2.2
hypertension (High Blood Pressure 2 0.6 2.33
Hypoxia 1.6 0.9 0.78
IgA nephropathy (IgAN) 0.9 0.6 0.5
Inflammatory Bowel Disease 3.2 1.8 0.78
Insomnia 1.1 1.2 -0.09
Intelligence 0.6 0.8 -0.33
Intracranial aneurysms 1.5 0.6 1.5
Irritable Bowel Syndrome 2.6 1.6 0.63
ischemic stroke 1.2 3.1 -1.58
Liver Cirrhosis 2.3 2.6 -0.13
Long COVID 2.4 2 0.2
Lung Cancer 1 0.1 9
Lymphoma 1 1
Mast Cell Issues / mastitis 1 1
ME/CFS with IBS 0.6 0.6
ME/CFS without IBS 0.6 0.6
Menopause 0.2 -0.2
Metabolic Syndrome 3.2 2.4 0.33
Mood Disorders 2.9 3.7 -0.28
Multiple Sclerosis 2.4 2.4
Multiple system atrophy (MSA) 1.2 1.2
myasthenia gravis 1 0 0
neuropathic pain 0.6 0.6
Neuropathy (all types) 1.1 -1.1
neuropsychiatric disorders (PANDAS, PANS) 0.6 0.3 1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.2 1.1 1
NonCeliac Gluten Sensitivity 0.6 0.6 0
Obesity 2.7 1.5 0.8
obsessive-compulsive disorder 1.7 1.2 0.42
Osteoarthritis 1.1 0.8 0.38
Osteoporosis 2.2 1.2 0.83
pancreatic cancer 0 0.3 0
Parkinson's Disease 2.4 2.8 -0.17
Polycystic ovary syndrome 1.9 1.1 0.73
Postural orthostatic tachycardia syndrome 0 0
Premenstrual dysphoric disorder 0.6 0.6
primary biliary cholangitis 0.2 0.3 -0.5
Primary sclerosing cholangitis 0.6 -0.6
Psoriasis 1.2 1.1 0.09
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2.7 2.2 0.23
Rosacea 0.6 0.3 1
Schizophrenia 0.9 2 -1.22
scoliosis 0.6 0.6
Sjögren syndrome 1.8 0.6 2
Sleep Apnea 1.1 0.9 0.22
Slow gastric motility / Gastroparesis 0.6 0.6 0
Small Intestinal Bacterial Overgrowth (SIBO) 0.6 0.6 0
Stress / posttraumatic stress disorder 1.8 0.6 2
Systemic Lupus Erythematosus 1 1.7 -0.7
Tourette syndrome 0.6 0.6
Type 1 Diabetes 2.2 1 1.2
Type 2 Diabetes 3.4 3 0.13
Ulcerative colitis 3.9 1.1 2.55
Unhealthy Ageing 0 1.4 0
Vitiligo 1.4 -1.4

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