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🍽️ Trichosanic acid {pomegranate seed oil}

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  1. Anti-inflammatory Effects: Punicic acid exhibits anti-inflammatory properties, which may help reduce inflammation and alleviate symptoms associated with inflammatory conditions such as rheumatoid arthritis, inflammatory bowel disease (IBD), and asthma. Punicic acid can inhibit the production of pro-inflammatory cytokines and mediators, thereby attenuating inflammatory responses and tissue damage.

  2. Cardiovascular Health: Punicic acid has been shown to have beneficial effects on cardiovascular health by reducing risk factors associated with heart disease. It can lower levels of LDL (low-density lipoprotein) cholesterol, commonly referred to as "bad" cholesterol, and increase levels of HDL (high-density lipoprotein) cholesterol, known as "good" cholesterol. Punicic acid may also help improve lipid profiles, reduce triglyceride levels, and prevent the development of atherosclerosis and cardiovascular events.

  3. Antioxidant Activity: Punicic acid possesses antioxidant properties, which help protect cells and tissues from oxidative stress and damage caused by free radicals. Antioxidants play a crucial role in maintaining overall health and reducing the risk of chronic diseases such as cancer, diabetes, and neurodegenerative disorders. Punicic acid's antioxidant activity may contribute to its potential health benefits and protective effects against oxidative damage.

  4. Skin Health: Pomegranate seed oil, rich in punicic acid, is often used in skincare products due to its moisturizing, anti-inflammatory, and antioxidant properties. Punicic acid may help promote skin health by enhancing skin barrier function, reducing inflammation, and protecting against UV-induced damage. It may also stimulate collagen production and improve skin elasticity, leading to a more youthful and radiant complexion.

  5. Anti-cancer Effects: Some research suggests that punicic acid may have anti-cancer properties and inhibit the growth and proliferation of cancer cells. Punicic acid can induce apoptosis (programmed cell death) in cancer cells, suppress tumor cell invasion and metastasis, and modulate signaling pathways involved in cancer development and progression. Pomegranate seed oil and punicic acid derivatives have been investigated for their potential as adjunctive treatments for various types of cancer, including breast, prostate, and colon cancer.

  6. Metabolic Health: Punicic acid may have beneficial effects on metabolic health and glucose metabolism. It can improve insulin sensitivity, reduce insulin resistance, and lower blood glucose levels, which may help prevent or manage type 2 diabetes and metabolic syndrome. Punicic acid's ability to modulate lipid metabolism and adipocyte function may also contribute to its metabolic benefits.

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Data Contradictions — Limits of Certainity

Impacted of Trichosanic acid {pomegranate seed oil} On Probiotics

Rank Probiotic Impact
species Lactobacillus acidophilus Increases
species Lactobacillus crispatus Increases
species Lactobacillus gasseri Increases
species Lactobacillus helveticus Increases
species Lactobacillus jensenii Increases
species Lactobacillus johnsonii Increases
species Lactobacillus kefiranofaciens Increases

Bacteria Impacted by Trichosanic acid {pomegranate seed oil}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
1 0 Desulfovibrionaceae family Decreases
1 0 Helicobacteraceae family Decreases
0 1 Erysipelotrichaceae family Decreases
0 1 Lactobacillaceae family Increases
0 1 Oscillospiraceae family Increases
0 1 Lachnospiraceae family Increases
2 0 Muribaculaceae family Increases
0 1 Helicobacter genus Decreases
0 1 Bilophila genus Decreases
1 0 Anaerotruncus genus Decreases
1 0 Blautia genus Decreases
1 0 Faecalibaculum genus Decreases
0 1 Desulfobaculum genus Decreases
0 1 Desulfocurvibacter genus Decreases
0 1 Desulfocurvus genus Decreases
0 1 Desulfohalovibrio genus Decreases
0 1 Flexispira genus Decreases
0 1 Fundidesulfovibrio genus Decreases
0 1 Halodesulfovibrio genus Decreases
0 1 Humidesulfovibrio genus Decreases
0 1 Mailhella genus Decreases
0 1 Nitratidesulfovibrio genus Decreases
0 1 Paradesulfovibrio (ex Waite et al. 2020) genus Decreases
0 1 Paucidesulfovibrio genus Decreases
0 1 Salidesulfovibrio genus Decreases
0 1 Wolinella genus Decreases
0 1 Maridesulfovibrio genus Decreases
0 1 Desulfovibrio genus Decreases
0 1 Megalodesulfovibrio genus Decreases
0 1 Desulfolutivibrio genus Decreases
0 1 Solidesulfovibrio genus Decreases
0 1 Oleidesulfovibrio genus Decreases
0 1 Oceanidesulfovibrio genus Decreases
0 1 Lawsonia genus Decreases
0 1 Pseudodesulfovibrio genus Decreases
0 1 Muribaculum genus Increases
0 1 Sodaliphilus genus Increases
0 1 Candidatus Amulumruptor genus Increases
0 1 Candidatus Homeothermus genus Increases
0 1 Paramuribaculum genus Increases
0 1 Duncaniella genus Increases
1 0 Lactobacillus genus Increases
1 0 Oscillibacter genus Increases
1 0 Roseburia genus Increases
0 1 environmental samples no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Anaerotruncus no rank Decreases
0 1 unclassified Desulfovibrionaceae no rank Decreases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 unclassified Lactobacillus no rank Increases
0 1 unclassified Muribaculaceae no rank Increases
0 1 unclassified Oscillibacter no rank Increases
0 1 unclassified Roseburia no rank Increases
0 1 Desulfovibrionales order Decreases
0 1 Campylobacterales order Decreases
0 1 Bacteroidales order Increases
0 1 Anaerotruncus colihominis species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Anaerotruncus massiliensis (ex Liu et al. 2021) species Decreases
0 1 Anaerotruncus massiliensis (ex Togo et al. 2019) species Decreases
0 1 Anaerotruncus rubiinfantis species Decreases
0 1 Lactobacillus ultunensis species Increases
0 1 Lactobacillus helveticus species Increases
0 1 Lactobacillus johnsonii species Increases
0 1 Lactobacillus kefiranofaciens species Increases
0 1 Lactobacillus amylolyticus species Increases
0 1 Lactobacillus acetotolerans species Increases
0 1 Lactobacillus amylovorus species Increases
0 1 Lactobacillus iners species Increases
0 1 Lactobacillus taiwanensis species Increases
0 1 Lactobacillus crispatus species Increases
0 1 Lactobacillus intestinalis species Increases
0 1 Lactobacillus acidophilus species Increases
0 1 Lactobacillus paragasseri species Increases
0 1 Lactobacillus jensenii species Increases
0 1 Lactobacillus gasseri species Increases
0 1 [Lactobacillus] rogosae species Increases
0 1 ATCC 15434 species Increases
0 1 Candidatus Oscillibacter avistercoris species Increases
0 1 Candidatus Oscillibacter excrementavium species Increases
0 1 Candidatus Oscillibacter pullicola species Increases
0 1 Lactobacillus alvei species Increases
0 1 Lactobacillus animata species Increases
0 1 Lactobacillus apis species Increases
0 1 Lactobacillus bombicola species Increases
0 1 Lactobacillus brevisimilis species Increases
0 1 Lactobacillus equicursoris species Increases
0 1 Lactobacillus faeni species Increases
0 1 Lactobacillus fornicalis species Increases
0 1 Lactobacillus gallinarum species Increases
0 1 Lactobacillus gigeriorum species Increases
0 1 Lactobacillus guizhouensis species Increases
0 1 Lactobacillus hamsteri species Increases
0 1 Lactobacillus helsingborgensis species Increases
0 1 Lactobacillus hominis species Increases
0 1 Lactobacillus intermedius species Increases
0 1 Lactobacillus japonicus species Increases
0 1 Lactobacillus kalixensis species Increases
0 1 Lactobacillus kitasatonis species Increases
0 1 Lactobacillus kullabergensis species Increases
0 1 Lactobacillus leichmannii species Increases
0 1 Lactobacillus letivazi species Increases
0 1 Lactobacillus mulieris species Increases
0 1 Lactobacillus panisapium species Increases
0 1 Lactobacillus pasteurii species Increases
0 1 Lactobacillus psittaci species Increases
0 1 Lactobacillus rodentium species Increases
0 1 Lactobacillus selangorensis species Increases
0 1 Lactobacillus sp. 7_1_47FAA species Increases
0 1 Lactobacillus sp. MYMRS/TEN2 species Increases
0 1 Lactobacillus terrae species Increases
0 1 Oscillibacter acetigenes species Increases
0 1 Oscillibacter massiliensis species Increases
0 1 Oscillibacter ruminantium species Increases
0 1 Oscillibacter valericigenes species Increases
0 1 Roseburia cecicola species Increases
0 1 Roseburia difficilis species Increases
0 1 Roseburia faecis species Increases
0 1 Roseburia inulinivorans species Increases
0 1 Roseburia lenta species Increases
0 1 Roseburia porci species Increases
0 1 Roseburia yibonii species Increases
0 1 Roseburia zhanii species Increases
0 1 Lactobacillus delbrueckii species Increases
0 1 Roseburia hominis species Increases
0 1 Roseburia rectibacter species Increases
0 1 Roseburia intestinalis species Increases
0 1 Oscillibacter hominis species Increases
0 1 Lactobacillus casei group species group Increases

Impact of Trichosanic acid {pomegranate seed oil} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.6 0.5 0.2
Acne 1 1
ADHD 1.1 1.5 -0.36
Age-Related Macular Degeneration and Glaucoma 0.5 0.6 -0.2
Allergic Rhinitis (Hay Fever) 2.4 0.3 7
Allergies 3 2.2 0.36
Allergy to milk products 0.3 0.8 -1.67
Alopecia (Hair Loss) 0.5 0.3 0.67
Alzheimer's disease 5.7 2.4 1.38
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.8 1.7 -1.13
Ankylosing spondylitis 1.7 1.5 0.13
Anorexia Nervosa 1.7 0.8 1.13
Antiphospholipid syndrome (APS) 1.1 -1.1
Asthma 3 1.5 1
Atherosclerosis 1.7 0.6 1.83
Atrial fibrillation 1.6 1.2 0.33
Autism 2.5 4 -0.6
Autoimmune Disease 2.1 2.1
Barrett esophagus cancer 0 0
benign prostatic hyperplasia 0.2 0.2
Bipolar Disorder 1.4 0.6 1.33
Brain Trauma 1.7 0.9 0.89
Breast Cancer 0.3 -0.3
Cancer (General) 0.7 0.7
Carcinoma 1.1 1.6 -0.45
Celiac Disease 2 3 -0.5
Cerebral Palsy 0.6 1.1 -0.83
Chronic Fatigue Syndrome 2.2 0.9 1.44
Chronic Kidney Disease 2 1.2 0.67
Chronic Lyme 0.6 0.6
Chronic Obstructive Pulmonary Disease (COPD) 0.8 2 -1.5
Coagulation / Micro clot triggering bacteria 0.6 0.5 0.2
Cognitive Function 1.4 1.3 0.08
Colorectal Cancer 3 3 0
Constipation 0.6 1 -0.67
Coronary artery disease 1.7 0.8 1.13
COVID-19 4.1 1.4 1.93
Crohn's Disease 3.8 3.5 0.09
Cushing's Syndrome (hypercortisolism) 0 0
cystic fibrosis 0.8 0.5 0.6
d-lactic acidosis (one form of brain fog) 1 -1
deep vein thrombosis 1.6 0.6 1.67
Denture Wearers Oral Shifts 0.6 0.6
Depression 5.6 3.9 0.44
Dermatomyositis 0.5 -0.5
Eczema 0.2 0.3 -0.5
Endometriosis 2.8 0.6 3.67
Epilepsy 1.4 0.8 0.75
erectile dysfunction 0.3 0.9 -2
Fibromyalgia 1.4 1.2 0.17
Functional constipation / chronic idiopathic constipation 1.4 1.7 -0.21
gallstone disease (gsd) 2.8 0.2 13
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.5 0.6 -0.2
Generalized anxiety disorder 1.4 0.4 2.5
giant cell arteritis 0.5 -0.5
Glioblastoma 0.5 0.5
Gout 0.5 0.9 -0.8
Graves' disease 1.5 1.4 0.07
Gulf War Syndrome 0.8 0.8
Hashimoto's thyroiditis 1.3 2.5 -0.92
Heart Failure 2.1 1.1 0.91
hemorrhagic stroke 0.3 -0.3
Hidradenitis Suppurativa 0.6 0.6
High Histamine/low DAO 1.2 -1.2
hypercholesterolemia (High Cholesterol) 0 0
hyperglycemia 1.2 1 0.2
Hyperlipidemia (High Blood Fats) 3.4 0.6 4.67
hypersomnia 0.3 1.1 -2.67
hypertension (High Blood Pressure 4.2 2.3 0.83
Hypothyroidism 0.5 0.7 -0.4
Hypoxia 0.6 1.2 -1
IgA nephropathy (IgAN) 1.5 0.3 4
Inflammatory Bowel Disease 3.5 1.5 1.33
Insomnia 1.5 2.7 -0.8
Intelligence 0.6 0.5 0.2
Intracranial aneurysms 1.6 0.2 7
Irritable Bowel Syndrome 2.7 2.3 0.17
ischemic stroke 2 0.6 2.33
Liver Cirrhosis 3.2 3 0.07
Long COVID 4.3 2.8 0.54
Low bone mineral density 1.1 1.1
Lung Cancer 1.6 0.5 2.2
Lymphoma 0 0
Mast Cell Issues / mastitis 0.6 0.6
ME/CFS with IBS 0.3 0.3
ME/CFS without IBS
Menopause 1.3 1.3
Metabolic Syndrome 5 3.3 0.52
Mood Disorders 5.2 3.6 0.44
multiple chemical sensitivity [MCS] 1.1 -1.1
Multiple Sclerosis 4.4 1.4 2.14
Multiple system atrophy (MSA) 1.5 -1.5
myasthenia gravis 0.6 0.3 1
neuropathic pain 1.3 0.5 1.6
Neuropathy (all types) 2 0.9 1.22
neuropsychiatric disorders (PANDAS, PANS) 0.3 0 0
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4.5 2.7 0.67
NonCeliac Gluten Sensitivity 1.1 0.2 4.5
Obesity 6.4 5 0.28
obsessive-compulsive disorder 0.9 0.5 0.8
Osteoarthritis 0.8 0.3 1.67
Osteoporosis 1.2 2.5 -1.08
pancreatic cancer 0.3 0.2 0.5
Parkinson's Disease 4.3 3.3 0.3
Peanut Allergy 0.3 0.6 -1
Polycystic ovary syndrome 3 3.1 -0.03
Premenstrual dysphoric disorder 0.5 0.5
primary biliary cholangitis 0.2 1.5 -6.5
Primary sclerosing cholangitis 0.3 1.3 -3.33
Psoriasis 1.7 0.6 1.83
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 5.4 3.6 0.5
Rosacea 1.8 0.3 5
Schizophrenia 3.9 2.3 0.7
scoliosis 1.1 -1.1
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 0.8 0.7 0.14
Sleep Apnea 1.1 1.3 -0.18
Slow gastric motility / Gastroparesis 0.6 0.6
Small Intestinal Bacterial Overgrowth (SIBO) 0.2 0.8 -3
Stress / posttraumatic stress disorder 0.9 1.2 -0.33
Systemic Lupus Erythematosus 2.8 1.3 1.15
Tic Disorder 0.3 0.2 0.5
Tourette syndrome 0.8 0.8
Type 1 Diabetes 2.5 0.9 1.78
Type 2 Diabetes 3.6 2.4 0.5
Ulcerative colitis 3.6 3 0.2
Unhealthy Ageing 2 0.6 2.33
Vitiligo 0.3 0.3 0

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