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Cardiovascular Health: Motherwort has been used traditionally to support cardiovascular health and promote circulation. It may help regulate heart rhythm, reduce palpitations, and strengthen the heart muscle. Leonurine, as a bioactive compound found in motherwort, may have vasodilatory effects, helping to relax blood vessels and lower blood pressure. Motherwort may also have mild anticoagulant properties, potentially reducing the risk of blood clots and improving blood flow.
Menstrual Health: Motherwort has been traditionally used to alleviate menstrual cramps, regulate menstrual cycles, and reduce menstrual discomfort. It may help relax the uterine muscles and reduce uterine contractions, easing menstrual pain and promoting a more regular menstrual cycle. Motherwort may also have mild hormonal effects, balancing estrogen levels and alleviating symptoms of menopause such as hot flashes and mood swings.
Anxiety and Stress: Motherwort has been used as a calming herb to promote relaxation and reduce anxiety and stress. It may have mild sedative properties, helping to calm the nervous system and promote a sense of tranquility. Leonurine may act on neurotransmitter systems in the brain, such as GABA (gamma-aminobutyric acid) receptors, which are involved in regulating anxiety and stress responses. Motherwort tea or supplements may be beneficial for individuals experiencing anxiety or nervous tension.
Uterine Health: Motherwort has been used traditionally to support uterine health and tone the uterine muscles. It may help strengthen the uterine wall and improve uterine tone, particularly after childbirth or during the postpartum period. Motherwort may also help regulate menstrual bleeding and reduce the risk of uterine fibroids or other gynecological conditions.
Digestive Health: Motherwort has been used as a digestive tonic to support healthy digestion and alleviate gastrointestinal discomfort. It may help relieve symptoms such as bloating, gas, and indigestion. Motherwort tea or tincture may stimulate digestive secretions, improve bile flow, and soothe digestive inflammation, promoting overall digestive health.
Anti-inflammatory Effects: Motherwort may have mild anti-inflammatory effects, helping to reduce inflammation in the body and alleviate symptoms of inflammatory conditions such as arthritis, rheumatism, and inflammatory bowel disease (IBD). Leonurine may modulate inflammatory pathways and reduce the production of pro-inflammatory cytokines, contributing to its anti-inflammatory properties.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Reduces |
| species | Bifidobacterium adolescentis | Reduces |
| species | Bifidobacterium animalis | Reduces |
| species | Bifidobacterium bifidum | Reduces |
| species | Bifidobacterium breve | Reduces |
| species | Bifidobacterium catenulatum | Reduces |
| species | Bifidobacterium longum | Reduces |
| species | Bifidobacterium pseudocatenulatum | Reduces |
| species | Bifidobacterium pseudolongum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Acne | 0.5 | -0.5 | |
| ADHD | 1.2 | 0.5 | 1.4 |
| Allergic Rhinitis (Hay Fever) | 0.5 | 1.5 | -2 |
| Allergies | 1.5 | 0.7 | 1.14 |
| Allergy to milk products | 0.5 | -0.5 | |
| Alzheimer's disease | 1.1 | 1.1 | 0 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 1.1 | 1.1 | |
| Ankylosing spondylitis | 1.1 | 1.1 | |
| Anorexia Nervosa | 0.5 | 0.5 | |
| Asthma | 1 | 0.7 | 0.43 |
| Atherosclerosis | 0.5 | 0.5 | |
| Atrial fibrillation | 0.5 | 0.5 | 0 |
| Autism | 1.1 | 1.6 | -0.45 |
| Autoimmune Disease | 0.5 | 0.5 | 0 |
| Biofilm | 0.2 | 0.2 | |
| Bipolar Disorder | 0.6 | 0.6 | |
| Brain Trauma | 0.5 | 0.5 | 0 |
| Cancer (General) | 0.7 | -0.7 | |
| Carcinoma | 0.5 | 0.5 | 0 |
| Celiac Disease | 0.8 | 1.1 | -0.38 |
| Cerebral Palsy | 1.1 | 1.1 | |
| Chronic Fatigue Syndrome | 0.5 | 0.5 | 0 |
| Cognitive Function | 0.5 | 0.5 | 0 |
| Colorectal Cancer | 0.5 | 1.1 | -1.2 |
| COVID-19 | 1.5 | 1.7 | -0.13 |
| Crohn's Disease | 1.1 | 1.1 | 0 |
| cystic fibrosis | 0.7 | -0.7 | |
| Denture Wearers Oral Shifts | 0 | 0 | |
| Depression | 1.9 | 1.9 | 0 |
| Dermatomyositis | 0.5 | -0.5 | |
| Eczema | 0.1 | 0.7 | -6 |
| Endometriosis | 0.5 | 0.5 | |
| Epilepsy | 0.5 | 0.5 | 0 |
| erectile dysfunction | 0.5 | -0.5 | |
| Fibromyalgia | 0.5 | 0.5 | 0 |
| Functional constipation / chronic idiopathic constipation | 1 | 0.5 | 1 |
| gallstone disease (gsd) | 0.5 | -0.5 | |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0 | 0 | |
| Generalized anxiety disorder | 0.9 | 1 | -0.11 |
| Gout | 0 | 0 | |
| Graves' disease | 0.5 | 0.5 | 0 |
| Gulf War Syndrome | 0 | 0.5 | 0 |
| Hashimoto's thyroiditis | 0.5 | 0.5 | 0 |
| Heart Failure | 1.1 | -1.1 | |
| High Histamine/low DAO | 0.5 | -0.5 | |
| hyperglycemia | 0.5 | -0.5 | |
| Hyperlipidemia (High Blood Fats) | 1.6 | 1.6 | |
| hypertension (High Blood Pressure | 1.1 | 1.4 | -0.27 |
| Hypothyroidism | 0.5 | -0.5 | |
| Hypoxia | 0.5 | 0.5 | 0 |
| IgA nephropathy (IgAN) | 1 | -1 | |
| Inflammatory Bowel Disease | 0.5 | 1.2 | -1.4 |
| Irritable Bowel Syndrome | 1.1 | 1 | 0.1 |
| ischemic stroke | 1 | 1 | |
| Liver Cirrhosis | 0.5 | 0.5 | 0 |
| Long COVID | 0.5 | 2.4 | -3.8 |
| Mast Cell Issues / mastitis | 0.5 | -0.5 | |
| ME/CFS with IBS | 0.5 | -0.5 | |
| ME/CFS without IBS | 0.5 | -0.5 | |
| Menopause | 0.7 | 0 | 0 |
| Metabolic Syndrome | 1.3 | 1.4 | -0.08 |
| Mood Disorders | 2.5 | 1.9 | 0.32 |
| Multiple Sclerosis | 1 | 0.5 | 1 |
| Multiple system atrophy (MSA) | 0.6 | -0.6 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.6 | 1.4 | -1.33 |
| NonCeliac Gluten Sensitivity | 0.5 | 0.5 | 0 |
| Obesity | 0.8 | 1.6 | -1 |
| obsessive-compulsive disorder | 0.6 | 0.5 | 0.2 |
| Osteoarthritis | 0.6 | -0.6 | |
| Osteoporosis | 0 | 0.3 | 0 |
| Parkinson's Disease | 0.5 | 1.2 | -1.4 |
| Polycystic ovary syndrome | 0.5 | 1.1 | -1.2 |
| Postural orthostatic tachycardia syndrome | 0.5 | -0.5 | |
| Premenstrual dysphoric disorder | 0.5 | 0.5 | |
| primary biliary cholangitis | 0 | 0 | |
| Psoriasis | 0.5 | 0.5 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1 | 0.5 | 1 |
| Rosacea | 0.5 | 0.5 | |
| Schizophrenia | 1.2 | 0.5 | 1.4 |
| Sjögren syndrome | 0.7 | -0.7 | |
| Sleep Apnea | 0.5 | 0.5 | |
| Slow gastric motility / Gastroparesis | 0.5 | -0.5 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.5 | -0.5 | |
| Stress / posttraumatic stress disorder | 0.5 | 0.5 | 0 |
| Systemic Lupus Erythematosus | 0.5 | -0.5 | |
| Tic Disorder | 0.5 | -0.5 | |
| Type 1 Diabetes | 0.6 | 1.3 | -1.17 |
| Type 2 Diabetes | 1.3 | 0.7 | 0.86 |
| Ulcerative colitis | 0.5 | 0.7 | -0.4 |
| Unhealthy Ageing | 0.6 | -0.6 | |
| Vitiligo | 0.5 | 0.5 | 0 |
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