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🍽️ Cholestyramine,Colesevelam,Colestipol {Bile Acid Sequestrant}

AI Engines For more Details: Perplexity  Kagi Labs  You 

  1. Lowering Cholesterol Levels: Bile acid sequestrants are effective in reducing low-density lipoprotein cholesterol (LDL-C) levels, also known as "bad" cholesterol, which is a major risk factor for cardiovascular disease. By binding to bile acids in the intestine, bile acid sequestrants prevent their reabsorption, leading to increased bile acid excretion in the feces and decreased bile acid pool size. As a compensatory mechanism, the liver utilizes circulating cholesterol to synthesize new bile acids, thereby reducing LDL-C levels in the blood.

  2. Cardiovascular Disease Risk Reduction: Lowering LDL-C levels with bile acid sequestrants has been shown to reduce the risk of cardiovascular events such as heart attack, stroke, and coronary artery disease. By lowering cholesterol levels, bile acid sequestrants help slow the progression of atherosclerosis (hardening and narrowing of arteries) and decrease the likelihood of plaque formation and rupture, which can lead to cardiovascular events.

  3. Treatment of Hyperlipidemia: Bile acid sequestrants are indicated for the treatment of hyperlipidemia, including heterozygous familial hypercholesterolemia and primary hyperlipidemia, particularly in patients who cannot tolerate or do not respond adequately to statin therapy. Bile acid sequestrants may be used as monotherapy or in combination with other cholesterol-lowering medications, such as statins, ezetimibe, or fibrates, to achieve target LDL-C levels and reduce cardiovascular risk.

  4. Gastrointestinal Side Effects: Bile acid sequestrants may cause gastrointestinal side effects such as constipation, bloating, flatulence, abdominal discomfort, and dyspepsia due to their physical binding action in the intestine. These side effects are dose-dependent and may vary among individual patients. Patients should be advised to increase dietary fiber intake, maintain adequate hydration, and engage in regular physical activity to help alleviate gastrointestinal symptoms associated with bile acid sequestrant therapy.

  5. Drug Interactions: Bile acid sequestrants may interact with other medications, including oral medications, by interfering with their absorption in the gastrointestinal tract. To minimize the risk of drug interactions, bile acid sequestrants should be administered at least 1 hour before or 4 hours after other medications, including vitamins, minerals, and fat-soluble medications such as warfarin, digoxin, thyroid hormones, and certain antiepileptic drugs.

  6. Nutrient Absorption: Bile acid sequestrants may impair the absorption of fat-soluble vitamins (A, D, E, K) and other nutrients from the intestine due to their binding action on bile acids. Patients receiving long-term bile acid sequestrant therapy should be monitored for nutritional deficiencies and may require supplementation with fat-soluble vitamins or other nutrients as needed.

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Check for interactions on Supp.AI   |   📚 PubMed Citations

Data Contradictions — Limits of Certainity

Impacted of Cholestyramine,Colesevelam,Colestipol {Bile Acid Sequestrant} On Probiotics

Rank Probiotic Impact
order Rhodospirillales Increases
species Bacteroides uniformis Increases
species Blautia hansenii Increases
species Blautia wexlerae Increases
species Clostridium beijerinckii Increases
species Clostridium butyricum Increases
species Lactobacillus acidophilus Increases
species Lactobacillus crispatus Increases
species Lactobacillus gasseri Increases
species Lactobacillus helveticus Increases
species Lactobacillus jensenii Increases
species Lactobacillus johnsonii Increases
species Lactobacillus kefiranofaciens Increases

Bacteria Impacted by Cholestyramine,Colesevelam,Colestipol {Bile Acid Sequestrant}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
1 0 Fusobacteriia class Increases
0 1 Treponemataceae family Increases
0 1 Atopobiaceae family Increases
0 1 Clostridiaceae family Increases
0 1 Coprobacillaceae family Increases
0 1 Eubacteriaceae family Increases
0 1 Lactobacillaceae family Increases
0 1 Prevotellaceae family Increases
0 1 Rikenellaceae family Increases
0 1 Sutterellaceae family Increases
0 2 Bacteroidaceae family Increases
0 2 Oscillospiraceae family Increases
1 1 Lachnospiraceae family Increases
0 1 Clostridioides genus Decreases
0 1 Roseburia genus Decreases
0 1 Bilophila genus Increases
0 1 Pauljensenia genus Increases
0 1 Coprobacter genus Increases
0 1 Hoylesella genus Increases
0 1 Acetatifactor genus Increases
0 1 Acetitomaculum genus Increases
0 1 Agathobacter genus Increases
0 1 Anaerobium genus Increases
0 1 Anaerobutyricum genus Increases
0 1 Anaerocolumna genus Increases
0 1 Anaeromicropila genus Increases
0 1 Anaeropeptidivorans genus Increases
0 1 Anaerosacchariphilus genus Increases
0 1 Anaerosporobacter genus Increases
0 1 Anaerostipes genus Increases
0 1 Anaerotaenia genus Increases
0 1 Anaerotignum genus Increases
0 1 Anthropogastromicrobium genus Increases
0 1 Bariatricus genus Increases
0 1 Brotaphodocola genus Increases
0 1 Butyribacter genus Increases
0 1 Butyrivibrio genus Increases
0 1 Candidatus Epulonipiscium genus Increases
0 1 Catenibacillus genus Increases
0 1 Catonella genus Increases
0 1 Chordicoccus genus Increases
0 1 Claveliimonas genus Increases
0 1 Coprococcus genus Increases
0 1 Cuneatibacter genus Increases
0 1 Diplocloster genus Increases
0 1 Dorea genus Increases
0 1 Eisenbergiella genus Increases
0 1 Enterocloster genus Increases
0 1 Extibacter genus Increases
0 1 Faecalicatena genus Increases
0 1 Faecalimonas genus Increases
0 1 Frisingicoccus genus Increases
0 1 Fusicatenibacter genus Increases
0 1 Gallintestinimicrobium genus Increases
0 1 Gluceribacter genus Increases
0 1 Herbinix genus Increases
0 1 Hespellia genus Increases
0 1 Hominifimenecus genus Increases
0 1 Hominisplanchenecus genus Increases
0 1 Hoministercoradaptatus genus Increases
0 1 Hominiventricola genus Increases
0 1 Jingyaoa genus Increases
0 1 Johnsonella genus Increases
0 1 Jutongia genus Increases
0 1 Kineothrix genus Increases
0 1 Lachnoanaerobaculum genus Increases
0 1 Lachnobacterium genus Increases
0 1 Lachnoclostridium genus Increases
0 1 Lachnospira genus Increases
0 1 Lachnotalea genus Increases
0 1 Lacrimispora genus Increases
0 1 Lientehia genus Increases
0 1 Luxibacter genus Increases
0 1 Marvinbryantia genus Increases
0 1 Mediterraneibacter genus Increases
0 1 Merdimonas genus Increases
0 1 Mobilitalea genus Increases
0 1 Moryella genus Increases
0 1 Muricomes genus Increases
0 1 Murimonas genus Increases
0 1 Niameybacter genus Increases
0 1 Novisyntrophococcus genus Increases
0 1 Oliverpabstia genus Increases
0 1 Oribacterium genus Increases
0 1 Parablautia genus Increases
0 1 Pararoseburia genus Increases
0 1 Parasporobacterium genus Increases
0 1 Porcincola genus Increases
0 1 Pseudobutyrivibrio genus Increases
0 1 Qiania genus Increases
0 1 Robinsoniella genus Increases
0 1 Schaedlerella genus Increases
0 1 Sellimonas genus Increases
0 1 Shuttleworthella genus Increases
0 1 Simiaoa genus Increases
0 1 Sporobacterium genus Increases
0 1 Sporofaciens genus Increases
0 1 Stomatobaculum genus Increases
0 1 Suonthocola genus Increases
0 1 Syntrophococcus genus Increases
0 1 Tyzzerella genus Increases
0 1 Waltera genus Increases
0 1 Wansuia genus Increases
0 1 Wujia genus Increases
0 1 Zhenhengia genus Increases
0 1 Klebsiella genus Increases
0 1 Segatella genus Increases
1 0 Alistipes genus Increases
1 0 Clostridium genus Increases
1 0 Coprobacillus genus Increases
1 0 Eubacterium genus Increases
1 0 Lactobacillus genus Increases
1 0 Olsenella genus Increases
1 0 Oscillospira genus Increases
1 0 Prevotella genus Increases
1 0 Ruminococcus genus Increases
1 0 Sutterella genus Increases
1 1 Blautia genus Increases
2 0 Bacteroides genus Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 environmental samples no rank Increases
0 1 Lachnospiraceae incertae sedis no rank Increases
0 1 unclassified Alistipes no rank Increases
0 1 unclassified Blautia no rank Increases
0 1 unclassified Clostridium no rank Increases
0 1 unclassified Coprobacillus no rank Increases
0 1 unclassified Eubacterium (in: firmicutes) no rank Increases
0 1 unclassified Fusobacteriota no rank Increases
0 1 unclassified Lachnospiraceae no rank Increases
0 1 unclassified Lactobacillus no rank Increases
0 1 unclassified Olsenella no rank Increases
0 1 unclassified Oscillospira no rank Increases
0 1 unclassified Prevotella no rank Increases
0 1 unclassified Ruminococcus no rank Increases
0 1 unclassified Sutterella no rank Increases
0 2 environmental samples no rank Increases
0 2 unclassified Bacteroides no rank Increases
0 1 Spirochaetales order Increases
0 1 Rhodospirillales order Increases
0 1 Fusobacteriales order Increases
0 1 Eubacteriales order Increases
1 0 Fusobacteriota phylum Increases
0 2 Bacteroides bouchesdurhonensis QSV445 Increases
1 0 Clostridioides difficile species Decreases
1 0 Roseburia intestinalis species Decreases
0 1 Klebsiella michiganensis species Increases
0 1 Enterobacter roggenkampii species Increases
0 1 Leyella lascolaii species Increases
0 1 Klebsiella aerogenes species Increases
0 1 Enterobacter cloacae species Increases
0 1 Klebsiella variicola species Increases
0 1 [Butyribacterium] methylotrophicum species Increases
0 1 [Eubacterium] cellulosolvens species Increases
0 1 [Lactobacillus] rogosae species Increases
0 1 Alistipes communis species Increases
0 1 Alistipes dispar species Increases
0 1 Alistipes finegoldii species Increases
0 1 Alistipes hominis species Increases
0 1 Alistipes ihumii species Increases
0 1 Alistipes indistinctus species Increases
0 1 Alistipes inops species Increases
0 1 Alistipes massiliensis species Increases
0 1 Alistipes megaguti species Increases
0 1 Alistipes montrealensis species Increases
0 1 Alistipes obesi species Increases
0 1 Alistipes onderdonkii species Increases
0 1 Alistipes provencensis species Increases
0 1 Alistipes putredinis species Increases
0 1 Alistipes senegalensis species Increases
0 1 Alistipes shahii species Increases
0 1 Alistipes timonensis species Increases
0 1 Blautia argi species Increases
0 1 Blautia caecimuris species Increases
0 1 Blautia coccoides species Increases
0 1 Blautia difficilis species Increases
0 1 Blautia faecicola species Increases
0 1 Blautia faecis species Increases
0 1 Blautia fusiformis species Increases
0 1 Blautia glucerasea species Increases
0 1 Blautia hansenii species Increases
0 1 Blautia hominis species Increases
0 1 Blautia hydrogenotrophica species Increases
0 1 Blautia intestinalis species Increases
0 1 Blautia lenta species Increases
0 1 Blautia liquoris species Increases
0 1 Blautia luti species Increases
0 1 Blautia marasmi species Increases
0 1 Blautia massiliensis (ex Durand et al. 2017) species Increases
0 1 Blautia obeum species Increases
0 1 Blautia producta species Increases
0 1 Blautia provencensis species Increases
0 1 Blautia pseudococcoides species Increases
0 1 Blautia schinkii species Increases
0 1 Blautia segnis species Increases
0 1 Blautia stercoris species Increases
0 1 Blautia tarda species Increases
0 1 Blautia wexlerae species Increases
0 1 Candidatus Alistipes avistercoris species Increases
0 1 Candidatus Alistipes cottocaccae species Increases
0 1 Candidatus Alistipes excrementavium species Increases
0 1 Candidatus Alistipes excrementigallinarum species Increases
0 1 Candidatus Alistipes excrementipullorum species Increases
0 1 Candidatus Alistipes faecigallinarum species Increases
0 1 Candidatus Alistipes intestinigallinarum species Increases
0 1 Candidatus Alistipes merdavium species Increases
0 1 Candidatus Alistipes merdipullorum species Increases
0 1 Candidatus Alistipes pullicola species Increases
0 1 Candidatus Alistipes pullistercoris species Increases
0 1 Candidatus Alistipes stercorigallinarum species Increases
0 1 Candidatus Alistipes stercoripullorum species Increases
0 1 Candidatus Blautia avicola species Increases
0 1 Candidatus Blautia avistercoris species Increases
0 1 Candidatus Blautia gallistercoris species Increases
0 1 Candidatus Blautia intestinavium species Increases
0 1 Candidatus Blautia merdigallinarum species Increases
0 1 Candidatus Blautia ornithocaccae species Increases
0 1 Candidatus Blautia pullicola species Increases
0 1 Candidatus Blautia pullistercoris species Increases
0 1 Candidatus Blautia stercorigallinarum species Increases
0 1 Candidatus Eubacterium faecale species Increases
0 1 Candidatus Eubacterium faecavium species Increases
0 1 Candidatus Eubacterium faecipullorum species Increases
0 1 Candidatus Olsenella avistercoris species Increases
0 1 Candidatus Olsenella excrementigallinarum species Increases
0 1 Candidatus Prevotella avicola species Increases
0 1 Candidatus Prevotella stercoripullorum species Increases
0 1 Clostridium aceticum species Increases
0 1 Clostridium acetireducens species Increases
0 1 Clostridium acetobutylicum species Increases
0 1 Clostridium acidisoli species Increases
0 1 Clostridium aestuarii species Increases
0 1 Clostridium akagii species Increases
0 1 Clostridium algidicarnis species Increases
0 1 Clostridium algifaecis species Increases
0 1 Clostridium aminobutyricum species Increases
0 1 Clostridium amylolyticum species Increases
0 1 Clostridium argentinense species Increases
0 1 Clostridium aurantibutyricum species Increases
0 1 Clostridium autoethanogenum species Increases
0 1 Clostridium baratii species Increases
0 1 Clostridium beijerinckii species Increases
0 1 Clostridium boliviensis species Increases
0 1 Clostridium bornimense species Increases
0 1 Clostridium botulinum species Increases
0 1 Clostridium bovifaecis species Increases
0 1 Clostridium bovipellis species Increases
0 1 Clostridium bowmanii species Increases
0 1 Clostridium butyricum species Increases
0 1 Clostridium cadaveris species Increases
0 1 Clostridium caliptrosporum species Increases
0 1 Clostridium carboxidivorans species Increases
0 1 Clostridium carnis species Increases
0 1 Clostridium cavendishii species Increases
0 1 Clostridium celatum species Increases
0 1 Clostridium cellulovorans species Increases
0 1 Clostridium chartatabidum species Increases
0 1 Clostridium chauvoei species Increases
0 1 Clostridium chromiireducens species Increases
0 1 Clostridium cochlearium species Increases
0 1 Clostridium colicanis species Increases
0 1 Clostridium collagenovorans species Increases
0 1 Clostridium combesii species Increases
0 1 Clostridium culturomicium species Increases
0 1 Clostridium cuniculi species Increases
0 1 Clostridium cylindrosporum species Increases
0 1 Clostridium diolis species Increases
0 1 Clostridium disporicum species Increases
0 1 Clostridium drakei species Increases
0 1 Clostridium estertheticum species Increases
0 1 Clostridium facile species Increases
0 1 Clostridium fallax species Increases
0 1 Clostridium felsineum species Increases
0 1 Clostridium fermenticellae species Increases
0 1 Clostridium fessum species Increases
0 1 Clostridium formicaceticum species Increases
0 1 Clostridium frigidicarnis species Increases
0 1 Clostridium frigoris species Increases
0 1 Clostridium fungisolvens species Increases
0 1 Clostridium fusiformis species Increases
0 1 Clostridium ganghwense species Increases
0 1 Clostridium gasigenes species Increases
0 1 Clostridium gelidum species Increases
0 1 Clostridium grantii species Increases
0 1 Clostridium haemolyticum species Increases
0 1 Clostridium homopropionicum species Increases
0 1 Clostridium hveragerdense species Increases
0 1 Clostridium hydrogeniformans species Increases
0 1 Clostridium intestinale species Increases
0 1 Clostridium isatidis species Increases
0 1 Clostridium jeddahitimonense species Increases
0 1 Clostridium kluyveri species Increases
0 1 Clostridium kogasense species Increases
0 1 Clostridium lacusfryxellense species Increases
0 1 Clostridium lentum species Increases
0 1 Clostridium liquoris species Increases
0 1 Clostridium ljungdahlii species Increases
0 1 Clostridium longisporum species Increases
0 1 Clostridium lundense species Increases
0 1 Clostridium magnum species Increases
0 1 Clostridium malenominatum species Increases
0 1 Clostridium manihotivorum species Increases
0 1 Clostridium massiliamazoniense species Increases
0 1 Clostridium merdae species Increases
0 1 Clostridium minihomine species Increases
0 1 Clostridium moniliforme species Increases
0 1 Clostridium neonatale species Increases
0 1 Clostridium nigeriense species Increases
0 1 Clostridium nitrophenolicum species Increases
0 1 Clostridium novyi species Increases
0 1 Clostridium oceanicum species Increases
0 1 Clostridium oryzae species Increases
0 1 Clostridium paraputrificum species Increases
0 1 Clostridium paridis species Increases
0 1 Clostridium pasteurianum species Increases
0 1 Clostridium perfringens species Increases
0 1 Clostridium phoceensis species Increases
0 1 Clostridium polyendosporum species Increases
0 1 Clostridium porci species Increases
0 1 Clostridium putrefaciens species Increases
0 1 Clostridium quinii species Increases
0 1 Clostridium rhizosphaerae species Increases
0 1 Clostridium ruminantium species Increases
0 1 Clostridium saccharobutylicum species Increases
0 1 Clostridium saccharoperbutylacetonicum species Increases
0 1 Clostridium sardiniense species Increases
0 1 Clostridium sartagoforme species Increases
0 1 Clostridium saudiense species Increases
0 1 Clostridium scatologenes species Increases
0 1 Clostridium schirmacherense species Increases
0 1 Clostridium segne species Increases
0 1 Clostridium senegalense species Increases
0 1 Clostridium septicum species Increases
0 1 Clostridium sp. AP-15 species Increases
0 1 Clostridium sp. TF01-11 species Increases
0 1 Clostridium sporogenes species Increases
0 1 Clostridium subterminale species Increases
0 1 Clostridium sulfidigenes species Increases
0 1 Clostridium swellfunianum species Increases
0 1 Clostridium taeniosporum species Increases
0 1 Clostridium tagluense species Increases
0 1 Clostridium tarantellae species Increases
0 1 Clostridium tepidiprofundi species Increases
0 1 Clostridium tepidum species Increases
0 1 Clostridium tertium species Increases
0 1 Clostridium tetani species Increases
0 1 Clostridium tetanomorphum species Increases
0 1 Clostridium thermarum species Increases
0 1 Clostridium thermoamylolyticum species Increases
0 1 Clostridium thermobutyricum species Increases
0 1 Clostridium thermopalmarium species Increases
0 1 Clostridium thiosulfatireducens species Increases
0 1 Clostridium tunisiense species Increases
0 1 Clostridium tyrobutyricum species Increases
0 1 Clostridium uliginosum species Increases
0 1 Clostridium vincentii species Increases
0 1 Clostridium vulturis species Increases
0 1 Coprobacillus cateniformis species Increases
0 1 Coprobacillus sp. D6 species Increases
0 1 Eubacterium barkeri species Increases
0 1 Eubacterium callanderi species Increases
0 1 Eubacterium coprostanoligenes species Increases
0 1 Eubacterium limosum species Increases
0 1 Eubacterium maltosivorans species Increases
0 1 Eubacterium multiforme species Increases
0 1 Eubacterium oxidoreducens species Increases
0 1 Eubacterium plexicaudatum species Increases
0 1 Eubacterium pyruvativorans species Increases
0 1 Eubacterium ramulus species Increases
0 1 Eubacterium rangiferina species Increases
0 1 Eubacterium ruminantium species Increases
0 1 Eubacterium segne species Increases
0 1 Eubacterium uniforme species Increases
0 1 Eubacterium ventriosum species Increases
0 1 Eubacterium xylanophilum species Increases
0 1 Faecalispora jeddahensis species Increases
0 1 Lactobacillus acetotolerans species Increases
0 1 Lactobacillus acidophilus species Increases
0 1 Lactobacillus alvei species Increases
0 1 Lactobacillus amylolyticus species Increases
0 1 Lactobacillus amylovorus species Increases
0 1 Lactobacillus animata species Increases
0 1 Lactobacillus apis species Increases
0 1 Lactobacillus bombicola species Increases
0 1 Lactobacillus brevisimilis species Increases
0 1 Lactobacillus crispatus species Increases
0 1 Lactobacillus delbrueckii species Increases
0 1 Lactobacillus equicursoris species Increases
0 1 Lactobacillus faeni species Increases
0 1 Lactobacillus fornicalis species Increases
0 1 Lactobacillus gallinarum species Increases
0 1 Lactobacillus gasseri species Increases
0 1 Lactobacillus gigeriorum species Increases
0 1 Lactobacillus guizhouensis species Increases
0 1 Lactobacillus hamsteri species Increases
0 1 Lactobacillus helsingborgensis species Increases
0 1 Lactobacillus helveticus species Increases
0 1 Lactobacillus hominis species Increases
0 1 Lactobacillus iners species Increases
0 1 Lactobacillus intermedius species Increases
0 1 Lactobacillus intestinalis species Increases
0 1 Lactobacillus japonicus species Increases
0 1 Lactobacillus jensenii species Increases
0 1 Lactobacillus johnsonii species Increases
0 1 Lactobacillus kalixensis species Increases
0 1 Lactobacillus kefiranofaciens species Increases
0 1 Lactobacillus kitasatonis species Increases
0 1 Lactobacillus kullabergensis species Increases
0 1 Lactobacillus leichmannii species Increases
0 1 Lactobacillus letivazi species Increases
0 1 Lactobacillus mulieris species Increases
0 1 Lactobacillus panisapium species Increases
0 1 Lactobacillus paragasseri species Increases
0 1 Lactobacillus pasteurii species Increases
0 1 Lactobacillus psittaci species Increases
0 1 Lactobacillus rodentium species Increases
0 1 Lactobacillus selangorensis species Increases
0 1 Lactobacillus taiwanensis species Increases
0 1 Lactobacillus terrae species Increases
0 1 Lactobacillus ultunensis species Increases
0 1 Olsenella phocaeensis species Increases
0 1 Olsenella profusa species Increases
0 1 Olsenella timonensis species Increases
0 1 Olsenella uli species Increases
0 1 Olsenella urininfantis species Increases
0 1 Oscillospira guilliermondii species Increases
0 1 Prevotella amnii species Increases
0 1 Prevotella aurantiaca species Increases
0 1 Prevotella bivia species Increases
0 1 Prevotella brunnea species Increases
0 1 Prevotella communis species Increases
0 1 Prevotella conceptionensis species Increases
0 1 Prevotella corporis species Increases
0 1 Prevotella dentalis species Increases
0 1 Prevotella dentasini species Increases
0 1 Prevotella denticola species Increases
0 1 Prevotella disiens species Increases
0 1 Prevotella falsenii species Increases
0 1 Prevotella fusca species Increases
0 1 Prevotella herbatica species Increases
0 1 Prevotella histicola species Increases
0 1 Prevotella intermedia species Increases
0 1 Prevotella jejuni species Increases
0 1 Prevotella marseillensis species Increases
0 1 Prevotella melaninogenica species Increases
0 1 Prevotella merdae species Increases
0 1 Prevotella micans species Increases
0 1 Prevotella multiformis species Increases
0 1 Prevotella nigrescens species Increases
0 1 Prevotella pallens species Increases
0 1 Prevotella pectinovora species Increases
0 1 Prevotella phocaeensis species Increases
0 1 Prevotella scopos species Increases
0 1 Prevotella sp. P5-119 species Increases
0 1 Prevotella veroralis species Increases
0 1 Ruminococcus albus species Increases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Increases
0 1 Ruminococcus bovis species Increases
0 1 Ruminococcus bromii species Increases
0 1 Ruminococcus callidus species Increases
0 1 Ruminococcus champanellensis species Increases
0 1 Ruminococcus difficilis species Increases
0 1 Ruminococcus flavefaciens species Increases
0 1 Ruminococcus gauvreauii species Increases
0 1 Ruminococcus hominis species Increases
0 1 Ruminococcus intestinalis species Increases
0 1 Ruminococcus turbiniformis species Increases
0 1 Sutterella faecalis species Increases
0 1 Sutterella massiliensis species Increases
0 1 Sutterella megalosphaeroides species Increases
0 1 Sutterella parvirubra species Increases
0 1 Sutterella sanguinus species Increases
0 1 Sutterella seckii species Increases
0 1 Sutterella stercoricanis species Increases
0 1 Sutterella wadsworthensis species Increases
0 1 Xylanibacter brevis species Increases
0 1 Xylanibacter oryzae species Increases
0 1 Xylanibacter rarus species Increases
0 1 Xylanibacter ruminicola species Increases
0 1 Klebsiella quasipneumoniae species Increases
0 2 Bacteroides acidifaciens species Increases
0 2 Bacteroides caccae species Increases
0 2 Bacteroides caecigallinarum species Increases
0 2 Bacteroides caecimuri species Increases
0 2 Bacteroides caecimuris species Increases
0 2 Bacteroides cellulosilyticus species Increases
0 2 Bacteroides chinchillae species Increases
0 2 Bacteroides clarus species Increases
0 2 Bacteroides congonensis species Increases
0 2 Bacteroides coprosuis species Increases
0 2 Bacteroides cutis species Increases
0 2 Bacteroides denticanum species Increases
0 2 Bacteroides difficilis species Increases
0 2 Bacteroides eggerthii species Increases
0 2 Bacteroides faecalis species Increases
0 2 Bacteroides faecichinchillae species Increases
0 2 Bacteroides faecis species Increases
0 2 Bacteroides faecium species Increases
0 2 Bacteroides finegoldii species Increases
0 2 Bacteroides fluxus species Increases
0 2 Bacteroides fragilis species Increases
0 2 Bacteroides galacturonicus species Increases
0 2 Bacteroides gallinaceum species Increases
0 2 Bacteroides gallinarum species Increases
0 2 Bacteroides graminisolvens species Increases
0 2 Bacteroides helcogenes species Increases
0 2 Bacteroides heparinolyticus species Increases
0 2 Bacteroides humanifaecis species Increases
0 2 Bacteroides ihuae species Increases
0 2 Bacteroides ilei species Increases
0 2 Bacteroides intestinalis species Increases
0 2 Bacteroides koreensis species Increases
0 2 Bacteroides kribbi species Increases
0 2 Bacteroides luhongzhouii species Increases
0 2 Bacteroides luti species Increases
0 2 Bacteroides mediterraneensis species Increases
0 2 Bacteroides muris (ex Fokt et al. 2023) species Increases
0 2 Bacteroides ndongoniae species Increases
0 2 Bacteroides nordii species Increases
0 2 Bacteroides oleiciplenus species Increases
0 2 Bacteroides ovatus species Increases
0 2 Bacteroides parvus species Increases
0 2 Bacteroides propionicifaciens species Increases
0 2 Bacteroides propionicigenes species Increases
0 2 Bacteroides pyogenes species Increases
0 2 Bacteroides reticulotermitis species Increases
0 2 Bacteroides rhinocerotis species Increases
0 2 Bacteroides rodentium species Increases
0 2 Bacteroides salyersiae species Increases
0 2 Bacteroides sp species Increases
0 2 Bacteroides sp. C13EG172 species Increases
0 2 Bacteroides stercorirosoris species Increases
0 2 Bacteroides stercoris species Increases
0 2 Bacteroides thetaiotaomicron species Increases
0 2 Bacteroides timonensis species Increases
0 2 Bacteroides uniformis species Increases
0 2 Bacteroides xylanisolvens species Increases
0 2 Bacteroides zhangwenhongii species Increases
0 2 Bacteroides zoogleoformans species Increases
0 2 Candidatus Bacteroides intestinigallinarum species Increases
1 0 Klebsiella pneumoniae species Increases
1 0 Segatella copri species Increases
0 1 Lactobacillus casei group species group Increases
0 1 Clostridioides difficile 002-P50-2011 strain Decreases
0 1 Clostridioides difficile 2007855 strain Decreases
0 1 Clostridioides difficile 342 strain Decreases
0 1 Clostridioides difficile 6041 strain Decreases
0 1 Clostridioides difficile 630 strain Decreases
0 1 Clostridioides difficile ATCC 43255 strain Decreases
0 1 Clostridioides difficile ATCC 9689 = DSM 1296 strain Decreases
0 1 Clostridioides difficile BI9 strain Decreases
0 1 Clostridioides difficile BJ08 strain Decreases
0 1 Clostridioides difficile CD196 strain Decreases
0 1 Clostridioides difficile CD40 strain Decreases
0 1 Clostridioides difficile DA00195 strain Decreases
0 1 Clostridioides difficile E85 strain Decreases
0 1 Clostridioides difficile F321 strain Decreases
0 1 Clostridioides difficile F501 strain Decreases
0 1 Clostridioides difficile genomovar ribotype_087 strain Decreases
0 1 Clostridioides difficile M120 strain Decreases
0 1 Clostridioides difficile NAP08 strain Decreases
0 1 Clostridioides difficile P28 strain Decreases
0 1 Clostridioides difficile P29 strain Decreases
0 1 Clostridioides difficile P38 strain Decreases
0 1 Clostridioides difficile P51 strain Decreases
0 1 Clostridioides difficile QCD-23m63 strain Decreases
0 1 Clostridioides difficile QCD-37x79 strain Decreases
0 1 Clostridioides difficile QCD-63q42 strain Decreases
0 1 Clostridioides difficile QCD-76w55 strain Decreases
0 1 Roseburia intestinalis L1-82 strain Decreases
0 1 Roseburia intestinalis M50/1 strain Decreases
0 1 Roseburia intestinalis XB6B4 strain Decreases
0 1 Clostridium sp. ASF502 strain Increases
0 1 Klebsiella pneumoniae JM45 strain Increases
0 1 Klebsiella pneumoniae KCTC 2242 strain Increases
0 1 Klebsiella pneumoniae KP-1 strain Increases
0 1 Segatella copri DSM 18205 strain Increases
0 1 Klebsiella pneumoniae subsp. ozaenae subspecies Increases
0 1 Klebsiella pneumoniae subsp. pneumoniae subspecies Increases
0 1 Klebsiella pneumoniae subsp. rhinoscleromatis subspecies Increases

Impact of Cholestyramine,Colesevelam,Colestipol {Bile Acid Sequestrant} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.9 -0.9
Acne 1.9 0.3 5.33
Addison's Disease (hypocortisolism) 0.6 -0.6
ADHD 2.3 3.6 -0.57
Age-Related Macular Degeneration and Glaucoma 1.2 0.4 2
Allergic Rhinitis (Hay Fever) 1.8 2.4 -0.33
Allergies 7.3 5.7 0.28
Allergy to milk products 1.3 3.9 -2
Alopecia (Hair Loss) 0.4 2.6 -5.5
Alzheimer's disease 8 7.8 0.03
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.6 2.8 -0.75
Ankylosing spondylitis 5.1 5.4 -0.06
Anorexia Nervosa 4.4 3.2 0.38
Antiphospholipid syndrome (APS) 0.6 0.5 0.2
Asthma 4 6.4 -0.6
Atherosclerosis 1.6 3.6 -1.25
Atrial fibrillation 3.9 5.5 -0.41
Autism 11.1 11.5 -0.04
Autoimmune Disease 1.4 1.1 0.27
benign prostatic hyperplasia 1.1 1.1
Biofilm 1.1 -1.1
Bipolar Disorder 1.8 3.9 -1.17
Brain Trauma 3.3 1.8 0.83
Breast Cancer 0.4 -0.4
Cancer (General) 1.4 0.6 1.33
Carcinoma 3.2 5 -0.56
Celiac Disease 6.7 3.7 0.81
Cerebral Palsy 2.4 2 0.2
Chronic Fatigue Syndrome 4.4 6.5 -0.48
Chronic Kidney Disease 3.3 2.6 0.27
Chronic Lyme 1.1 0.3 2.67
Chronic Obstructive Pulmonary Disease (COPD) 2.5 3.1 -0.24
Chronic Urticaria (Hives) 1.6 1.2 0.33
Coagulation / Micro clot triggering bacteria 2.6 0.8 2.25
Cognitive Function 2.6 5.7 -1.19
Colorectal Cancer 4.1 9.7 -1.37
Constipation 1.3 3.1 -1.38
Coronary artery disease 4.5 2.9 0.55
COVID-19 13.2 9.9 0.33
Crohn's Disease 8.7 10 -0.15
Cushing's Syndrome (hypercortisolism) 0.6 0.1 5
cystic fibrosis 1.3 1.1 0.18
d-lactic acidosis (one form of brain fog) 1 -1
deep vein thrombosis 2.8 2.3 0.22
Denture Wearers Oral Shifts 0.6 0.2 2
Depression 11.9 12.3 -0.03
Dermatomyositis 1 -1
Eczema 2 1.8 0.11
Endometriosis 2.6 5.1 -0.96
Eosinophilic Esophagitis 0.3 0.6 -1
Epilepsy 2.6 5.8 -1.23
erectile dysfunction 0.9 2 -1.22
Fibromyalgia 4.7 3.5 0.34
Functional constipation / chronic idiopathic constipation 6 8 -0.33
gallstone disease (gsd) 1.8 4 -1.22
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 2.4 2.6 -0.08
Generalized anxiety disorder 2.8 2.3 0.22
giant cell arteritis 0.6 0.3 1
Glioblastoma 1.5 0.6 1.5
Gout 1.5 2.8 -0.87
Graves' disease 4.8 3.1 0.55
Gulf War Syndrome 0.8 2 -1.5
Halitosis 0.4 2.5 -5.25
Hashimoto's thyroiditis 3.4 5.5 -0.62
Heart Failure 4.4 5.2 -0.18
hemorrhagic stroke 0.6 2.2 -2.67
Hemorrhoidal disease, Hemorrhoids, Piles 0.6 -0.6
Hidradenitis Suppurativa 0.4 1.5 -2.75
High Histamine/low DAO 1.3 2.4 -0.85
hypercholesterolemia (High Cholesterol) 1.5 -1.5
hyperglycemia 1.6 0.6 1.67
Hyperlipidemia (High Blood Fats) 2.4 0.7 2.43
hypersomnia 1 0.9 0.11
hypertension (High Blood Pressure 6.9 8.5 -0.23
Hypothyroidism 1.9 1.3 0.46
Hypoxia 0.9 2.4 -1.67
IgA nephropathy (IgAN) 6.1 3.1 0.97
Inflammatory Bowel Disease 10.5 6.5 0.62
Insomnia 5 4.9 0.02
Intelligence 2.1 3.3 -0.57
Intracranial aneurysms 2.7 2.7 0
Irritable Bowel Syndrome 7.8 8.6 -0.1
ischemic stroke 2.6 4.7 -0.81
Juvenile idiopathic arthritis 1.5 -1.5
Liver Cirrhosis 5.6 9.2 -0.64
Long COVID 10.1 8.2 0.23
Low bone mineral density 2.4 0.8 2
Lung Cancer 2.6 0.5 4.2
Lymphoma 0.7 0.7
Mast Cell Issues / mastitis 2.9 0.4 6.25
ME/CFS with IBS 0.8 1.2 -0.5
ME/CFS without IBS 0.8 1.5 -0.88
membranous nephropathy 0.6 -0.6
Menopause 1.2 1.1 0.09
Metabolic Syndrome 9.7 11.3 -0.16
Mood Disorders 10.8 11.7 -0.08
multiple chemical sensitivity [MCS] 0.4 0.6 -0.5
Multiple Sclerosis 7.6 5.6 0.36
Multiple system atrophy (MSA) 1 0.8 0.25
myasthenia gravis 0.9 1.5 -0.67
neuropathic pain 1.4 0.3 3.67
Neuropathy (all types) 0.4 2 -4
neuropsychiatric disorders (PANDAS, PANS) 0.4 0.6 -0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 7.3 10 -0.37
NonCeliac Gluten Sensitivity 1.2 1.3 -0.08
Obesity 11.3 11.7 -0.04
obsessive-compulsive disorder 6 4.9 0.22
Osteoarthritis 1.2 4.3 -2.58
Osteoporosis 3.1 4 -0.29
pancreatic cancer 0.4 0.3 0.33
Parkinson's Disease 9.9 10.6 -0.07
Peanut Allergy 1.4 1.4
Polycystic ovary syndrome 6.2 6.6 -0.06
Postural orthostatic tachycardia syndrome 0.3 0.8 -1.67
Premenstrual dysphoric disorder 0.2 0.6 -2
primary biliary cholangitis 1.3 2.5 -0.92
Primary sclerosing cholangitis 3.1 3.6 -0.16
Psoriasis 3.4 3.3 0.03
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 7.2 9.5 -0.32
Rosacea 1.2 0.8 0.5
Schizophrenia 5.9 9.1 -0.54
scoliosis 1.3 1.3 0
sensorineural hearing loss 0.4 0.9 -1.25
Sjögren syndrome 3.3 2.6 0.27
Sleep Apnea 2.5 1.9 0.32
Slow gastric motility / Gastroparesis 1.2 2.4 -1
Small Intestinal Bacterial Overgrowth (SIBO) 4 -4
Stress / posttraumatic stress disorder 2.3 3.1 -0.35
Systemic Lupus Erythematosus 5.4 5.6 -0.04
Tic Disorder 1.7 2.1 -0.24
Tourette syndrome 1.5 0.2 6.5
Type 1 Diabetes 4 6.6 -0.65
Type 2 Diabetes 8.5 10.6 -0.25
Ulcerative colitis 8.4 9 -0.07
Unhealthy Ageing 3.3 3.1 0.06
Vitiligo 1 2 -1

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