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🍽️ Tosufloxacin hydrochloride

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  1. Bacterial Infections: Tosufloxacin hydrochloride is effective against a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and sexually transmitted infections (STIs). It works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication, transcription, and repair.

  2. Respiratory Tract Infections: Tosufloxacin hydrochloride may be prescribed for the treatment of bacterial pneumonia, bronchitis, and sinusitis caused by susceptible bacteria.

  3. Urinary Tract Infections: It is commonly used to treat urinary tract infections (UTIs), including cystitis and pyelonephritis, caused by susceptible bacteria.

  4. Skin and Soft Tissue Infections: Tosufloxacin hydrochloride may be prescribed for the treatment of bacterial skin infections such as cellulitis, impetigo, and infected wounds.

  5. Sexually Transmitted Infections: It may be used to treat STIs such as gonorrhea and chlamydia when other antibiotics are not suitable or when the bacteria are resistant to other antibiotics.

  6. Dosage and Administration: Tosufloxacin hydrochloride is typically administered orally in the form of tablets or capsules. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's age and renal function.

  7. Adverse Effects: Common side effects of tosufloxacin hydrochloride may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and rash. Less commonly, it may cause tendon rupture, peripheral neuropathy, and central nervous system effects such as confusion or hallucinations. It may also prolong the QT interval on an electrocardiogram (ECG), increasing the risk of arrhythmias.

  8. Drug Interactions: Tosufloxacin hydrochloride may interact with other medications, including antacids containing magnesium or aluminum, iron supplements, and certain anticoagulants. Patients should inform their healthcare provider about all medications they are taking before starting tosufloxacin therapy.

  9. Pregnancy and Lactation: Tosufloxacin hydrochloride should be used with caution during pregnancy and lactation, as its safety profile in pregnant or breastfeeding women has not been well established. The benefits of treatment should be weighed against the potential risks to the fetus or breastfeeding infant.

  10. Resistance: As with other antibiotics, the inappropriate use of tosufloxacin hydrochloride can contribute to the development of bacterial resistance. It is essential to use tosufloxacin judiciously and according to healthcare provider's instructions to minimize the emergence of resistance.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of Tosufloxacin hydrochloride On Probiotics

Rank Probiotic Impact
genus Bacillus Reduces
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by Tosufloxacin hydrochloride

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Staphylococcaceae family Decreases
1 0 Staphylococcus genus Decreases
0 1 Collinsella genus Decreases
0 1 Clostridium genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Streptococcus genus Decreases
0 1 Bilophila genus Decreases
0 1 Blautia genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Escherichia genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Coprococcus genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Odoribacter genus Decreases
0 1 Veillonella genus Decreases
0 1 Clostridioides genus Decreases
0 1 Dorea genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Eggerthella genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Lachnospira genus Decreases
0 1 Enterocloster genus Decreases
0 1 Segatella genus Decreases
0 1 Roseburia genus Decreases
0 1 Agathobacter genus Decreases
1 0 Akkermansia genus Decreases
0 1 Shigella genus Decreases
0 1 Parolsenella genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Wansuia genus Decreases
0 1 Flavonifractor genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Wujia genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Coprobacter genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Olsenella genus Decreases
0 1 Massilistercora genus Decreases
0 1 Simiaoa genus Decreases
0 1 Anaerostipes genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Qiania genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Christensenella genus Decreases
0 1 Treponema genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Eubacterium genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Faecalibacillus genus Decreases
0 1 Vescimonas genus Decreases
0 1 Longicatena genus Decreases
0 1 Adlercreutzia genus Decreases
0 1 Lactococcus genus Decreases
0 1 Monoglobus genus Decreases
0 1 Fannyhessea genus Decreases
0 1 Leyella genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Prevotella genus Decreases
0 1 Bacillus genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Lachnoclostridium genus Decreases
0 1 Faecalibaculum genus Decreases
0 1 Faecalibacterium genus Decreases
0 1 Parvimonas genus Decreases
0 1 Phoenicibacter genus Decreases
0 1 Gemella genus Decreases
0 1 Intestinimonas genus Decreases
0 1 Acutalibacter genus Decreases
0 1 Hungatella genus Decreases
0 1 Solibaculum genus Decreases
0 1 Flintibacter genus Decreases
0 1 Chordicoccus genus Decreases
0 1 Leuconostoc genus Decreases
0 1 Mogibacterium genus Decreases
0 1 Allocoprobacillus genus Decreases
0 1 Butyricicoccus genus Decreases
0 1 Butyricimonas genus Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Staphylococcus no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Blautia obeum species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Coprococcus comes species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Escherichia coli species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia hominis species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Segatella copri species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Veillonella parvula species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Veillonella rodentium species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Veillonella dispar species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Segatella bryantii species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Shigella boydii species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Veillonella nakazawae species Decreases
0 1 Coprococcus catus species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Parolsenella catena species Decreases
0 1 Dorea longicatena species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Blautia liquoris species Decreases
0 1 Veillonella rogosae species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Staphylococcus agnetis species Decreases
0 1 Staphylococcus argenteus species Decreases
0 1 Staphylococcus arlettae species Decreases
0 1 Staphylococcus aureus species Decreases
0 1 Staphylococcus auricularis species Decreases
0 1 Staphylococcus caeli species Decreases
0 1 Staphylococcus capitis species Decreases
0 1 Staphylococcus caprae species Decreases
0 1 Staphylococcus carnosus species Decreases
0 1 Staphylococcus chromogenes species Decreases
0 1 Staphylococcus coagulans species Decreases
0 1 Staphylococcus cohnii species Decreases
0 1 Staphylococcus condimenti species Decreases
0 1 Staphylococcus debuckii species Decreases
0 1 Staphylococcus devriesei species Decreases
0 1 Staphylococcus edaphicus species Decreases
0 1 Staphylococcus epidermidis species Decreases
0 1 Staphylococcus equorum species Decreases
0 1 Staphylococcus felis species Decreases
0 1 Staphylococcus gallinarum species Decreases
0 1 Staphylococcus haemolyticus species Decreases
0 1 Staphylococcus hominis species Decreases
0 1 Staphylococcus hyicus species Decreases
0 1 Staphylococcus kloosii species Decreases
0 1 Staphylococcus lloydii species Decreases
0 1 Staphylococcus lugdunensis species Decreases
0 1 Staphylococcus lutrae species Decreases
0 1 Staphylococcus massiliensis species Decreases
0 1 Staphylococcus muscae species Decreases
0 1 Staphylococcus nepalensis species Decreases
0 1 Staphylococcus pasteuri species Decreases
0 1 Staphylococcus pasteuri_A species Decreases
0 1 Staphylococcus petrasii species Decreases
0 1 Staphylococcus pettenkoferi species Decreases
0 1 Staphylococcus piscifermentans species Decreases
0 1 Staphylococcus pragensis species Decreases
0 1 Staphylococcus pseudolugdunensis species Decreases
0 1 Staphylococcus pseudoxylosus species Decreases
0 1 Staphylococcus ratti species Decreases
0 1 Staphylococcus saccharolyticus species Decreases
0 1 Staphylococcus saprophyticus species Decreases
0 1 Staphylococcus schleiferi species Decreases
0 1 Staphylococcus schweitzeri species Decreases
0 1 Staphylococcus simiae species Decreases
0 1 Staphylococcus simulans species Decreases
0 1 Staphylococcus succinus species Decreases
0 1 Staphylococcus ureilyticus species Decreases
0 1 Staphylococcus warneri species Decreases
0 1 Staphylococcus xylosus species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Christensenella minuta species Decreases
0 1 Flavonifractor plautii species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Bacteroides sp. M10 species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Blautia parvula species Decreases
0 1 Streptococcus australis species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Blautia argi species Decreases
0 1 Leyella stercorea species Decreases
0 1 Shigella sonnei species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Bacteroides faecium species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Actinomyces oris species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Streptococcus suis species Decreases
0 1 Veillonella atypica species Decreases
0 1 Treponema peruense species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Parvimonas micra species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Hungatella hathewayi species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Prevotella intermedia species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Bacteroides caecimuris species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Coprobacter fastidiosus species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Treponema denticola species Decreases
0 1 Ruminococcus albus species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Leyella lascolaii species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Enterocloster clostridioformis species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Alistipes communis species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Bifidobacterium bifidum species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Alistipes senegalensis species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Alistipes shahii species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Butyricimonas faecalis species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Paraprevotella clara species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Prevotella bivia species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Blautia hansenii species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Alistipes dispar species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Parabacteroides johnsonii species Decreases
0 1 Blautia producta species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Alistipes finegoldii species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Streptococcus sp. A12 species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Alistipes indistinctus species Decreases
0 1 Alistipes onderdonkii species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Prevotella dentalis species Decreases
0 1 Staphylococcus intermedius group species group Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of Tosufloxacin hydrochloride on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 1.4 1.4
Acne 0.3 0.6 -1
ADHD 6.7 1.6 3.19
Age-Related Macular Degeneration and Glaucoma 1.2 0.5 1.4
Allergic Rhinitis (Hay Fever) 5.5 4.4 0.25
Allergies 11.3 6.1 0.85
Allergy to milk products 4.7 2.2 1.14
Alopecia (Hair Loss) 2.6 0.2 12
Alzheimer's disease 11.7 12.5 -0.07
Amyotrophic lateral sclerosis (ALS) Motor Neuron 5.6 1.9 1.95
Ankylosing spondylitis 8 2.8 1.86
Anorexia Nervosa 3 5.5 -0.83
Antiphospholipid syndrome (APS) 2.8 0.6 3.67
Asthma 9.9 4.8 1.06
Atherosclerosis 4.3 2.9 0.48
Atrial fibrillation 6.6 4.7 0.4
Autism 16.8 16 0.05
Autoimmune Disease 1.9 1.6 0.19
Barrett esophagus cancer 1 0.5 1
benign prostatic hyperplasia 1.3 0.6 1.17
Biofilm 4.9 4.9
Bipolar Disorder 4.6 2.7 0.7
Brain Trauma 1.9 2.9 -0.53
Breast Cancer 1.4 1.4
Cancer (General) 1.6 4.2 -1.63
Carcinoma 8.2 4.7 0.74
Celiac Disease 6.3 7.1 -0.13
Cerebral Palsy 3.2 2.4 0.33
Chronic Fatigue Syndrome 10.6 10 0.06
Chronic Kidney Disease 6.9 4.9 0.41
Chronic Lyme 0.6 1 -0.67
Chronic Obstructive Pulmonary Disease (COPD) 4.8 3.6 0.33
Chronic Urticaria (Hives) 2.6 2 0.3
Coagulation / Micro clot triggering bacteria 2.8 2.8 0
Cognitive Function 4 3 0.33
Colorectal Cancer 12.6 4.7 1.68
Constipation 2.9 1.2 1.42
Coronary artery disease 5.2 5.2 0
COVID-19 18 19.9 -0.11
Crohn's Disease 16.4 11.1 0.48
Cushing's Syndrome (hypercortisolism) 0.2 1.1 -4.5
cystic fibrosis 1.3 2.7 -1.08
d-lactic acidosis (one form of brain fog) 1 1
deep vein thrombosis 4.2 2.8 0.5
Denture Wearers Oral Shifts 2.9 2.9
Depression 19.8 16 0.24
Dermatomyositis 0.8 0.5 0.6
Eczema 4.4 3.4 0.29
Endometriosis 5.7 3.7 0.54
Eosinophilic Esophagitis 0.6 1.1 -0.83
Epilepsy 7 4.1 0.71
erectile dysfunction 2.6 0.6 3.33
Fibromyalgia 5.7 3.7 0.54
Functional constipation / chronic idiopathic constipation 9.9 7.4 0.34
gallstone disease (gsd) 5.7 2.2 1.59
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 3 2.5 0.2
Generalized anxiety disorder 5.8 3.8 0.53
giant cell arteritis 0.5 -0.5
Glioblastoma 0.1 0.9 -8
Gout 3.5 1.9 0.84
Graves' disease 3.2 4.9 -0.53
Gulf War Syndrome 2 2.8 -0.4
Halitosis 3.1 0.6 4.17
Hashimoto's thyroiditis 6.5 3.6 0.81
Heart Failure 8.2 4.1 1
hemorrhagic stroke 1.7 1.7
Hidradenitis Suppurativa 3.4 0.5 5.8
High Histamine/low DAO 2.9 1.2 1.42
hypercholesterolemia (High Cholesterol) 1.7 0.8 1.13
hyperglycemia 3.6 3.2 0.13
Hyperlipidemia (High Blood Fats) 2.4 0.7 2.43
hypersomnia 0.3 1.7 -4.67
hypertension (High Blood Pressure 9.3 10.7 -0.15
Hypothyroidism 1.4 2.8 -1
Hypoxia 3.9 0.1 38
IgA nephropathy (IgAN) 3.6 7.1 -0.97
Inflammatory Bowel Disease 15.8 16.3 -0.03
Insomnia 4.8 5.9 -0.23
Intelligence 3 1.1 1.73
Intracranial aneurysms 2.6 1.4 0.86
Irritable Bowel Syndrome 12.6 9.6 0.31
ischemic stroke 4.8 2.8 0.71
Juvenile idiopathic arthritis 0.1 0.1 0
Liver Cirrhosis 14 9.6 0.46
Long COVID 13 14 -0.08
Low bone mineral density 0.1 2 -19
Lung Cancer 2 2.5 -0.25
Lymphoma 0.8 0.1 7
Mast Cell Issues / mastitis 2.6 1.6 0.63
ME/CFS with IBS 1.7 3.5 -1.06
ME/CFS without IBS 3 2.9 0.03
membranous nephropathy 0.6 0.6
Menopause 2.8 1.2 1.33
Metabolic Syndrome 15.2 14.8 0.03
Mood Disorders 19.6 13.7 0.43
multiple chemical sensitivity [MCS] 2.2 0.5 3.4
Multiple Sclerosis 12.2 9.8 0.24
Multiple system atrophy (MSA) 2.6 1.5 0.73
myasthenia gravis 1.5 1.2 0.25
neuropathic pain 0.5 4 -7
Neuropathy (all types) 2.1 2.2 -0.05
neuropsychiatric disorders (PANDAS, PANS) 1.6 0.2 7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 9.4 8.9 0.06
NonCeliac Gluten Sensitivity 3.1 1.1 1.82
Obesity 19 15.6 0.22
obsessive-compulsive disorder 8.9 6.9 0.29
Osteoarthritis 5.1 2.9 0.76
Osteoporosis 4.3 3.4 0.26
pancreatic cancer 2.1 0.5 3.2
Parkinson's Disease 15.4 12.5 0.23
Polycystic ovary syndrome 10.5 5.8 0.81
Postural orthostatic tachycardia syndrome 0.6 1.1 -0.83
Premenstrual dysphoric disorder 1.5 0.6 1.5
primary biliary cholangitis 1.7 2.7 -0.59
Primary sclerosing cholangitis 4.6 5 -0.09
Psoriasis 6.8 4.8 0.42
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 13.9 7.5 0.85
Rosacea 2.4 1 1.4
Schizophrenia 12.7 6.2 1.05
scoliosis 1.6 1.7 -0.06
sensorineural hearing loss 0.5 0.1 4
Sjögren syndrome 5.1 4.6 0.11
Sleep Apnea 3.7 2.7 0.37
Slow gastric motility / Gastroparesis 2.3 0.7 2.29
Small Intestinal Bacterial Overgrowth (SIBO) 4.5 0.6 6.5
Stress / posttraumatic stress disorder 5.7 4.4 0.3
Systemic Lupus Erythematosus 8.4 4.1 1.05
Tic Disorder 2.3 2.8 -0.22
Tourette syndrome 1.5 0.5 2
Type 1 Diabetes 7.9 6.8 0.16
Type 2 Diabetes 16.4 13.5 0.21
Ulcerative colitis 11.8 12.1 -0.03
Unhealthy Ageing 8.3 4.3 0.93
Vitiligo 3.9 2.8 0.39

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