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🍽️ Homatropine hydrobromide (R,S)

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  1. Ophthalmic Uses:

    • Mydriasis: Homatropine hydrobromide is used to dilate the pupil for various diagnostic procedures and eye surgeries.
    • Cycloplegia: It temporarily paralyzes accommodation, which is useful in assessing refractive errors and determining the appropriate prescription for corrective lenses.

  2. Respiratory Conditions:

    • Cough Suppressant: Homatropine hydrobromide is sometimes combined with other medications, such as hydrocodone, to suppress cough reflexes. It acts as an antitussive by reducing the sensitivity of cough receptors in the airways.

  3. Gastrointestinal Conditions:

    • Antispasmodic: Homatropine hydrobromide can be used to relieve spasms or cramps in the gastrointestinal tract. It works by inhibiting the action of acetylcholine, a neurotransmitter involved in muscle contraction.

  4. Off-Label Uses:

    • Motion Sickness: Due to its anticholinergic properties, homatropine hydrobromide may be used off-label to alleviate symptoms of motion sickness.
    • Prevention of Nausea and Vomiting: In some cases, it may be prescribed to prevent nausea and vomiting, particularly in combination with other medications.

  5. Diagnostic Procedures:

    • Diagnostic Testing: Homatropine hydrobromide may be used in certain diagnostic tests to assess autonomic nervous system function or to induce specific physiological responses.

  6. Side Effects:

    • Cognitive Issues: As mentioned, homatropine hydrobromide can cause cognitive impairment, including confusion, memory problems, and difficulty concentrating, especially at higher doses or with prolonged use.
    • Dry Mouth: Anticholinergic medications like homatropine hydrobromide commonly cause dry mouth (xerostomia).
    • Blurred Vision: Temporary blurring of vision is a common side effect, particularly after ophthalmic use.
    • Increased Intraocular Pressure: Prolonged use of homatropine hydrobromide in the eye can increase intraocular pressure, which may be problematic in individuals with certain eye conditions such as glaucoma.
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Data Contradictions — Limits of Certainity

Impacted of Homatropine hydrobromide (R,S) On Probiotics

Rank Probiotic Impact

Bacteria Impacted by Homatropine hydrobromide (R,S)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Bacteroides genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Streptococcus genus Decreases
0 1 Thomasclavelia genus Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Bacteroides fragilis species Decreases

Impact of Homatropine hydrobromide (R,S) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.3 0.3
ADHD 0.3 0.3
Allergic Rhinitis (Hay Fever) 0.6 0.3 1
Allergies 0 0.3 0
Allergy to milk products 0.3 0.3 0
Alzheimer's disease 0.3 0.6 -1
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0 0
Ankylosing spondylitis 0.6 0.3 1
Anorexia Nervosa 0.3 0.6 -1
Antiphospholipid syndrome (APS) 0.3 0.3
Asthma 0.9 0.6 0.5
Atherosclerosis 0.3 0.3
Atrial fibrillation 0.6 0.3 1
Autism 0.6 0.6 0
Autoimmune Disease 0.3 0.3
Barrett esophagus cancer 0.3 -0.3
benign prostatic hyperplasia 0.3 -0.3
Biofilm 0.3 0.3
Bipolar Disorder 0.3 0.3
Brain Trauma 0.3 0.3 0
Carcinoma 0.6 0.3 1
Celiac Disease 0.6 0.3 1
Cerebral Palsy 0.6 0.3 1
Chronic Fatigue Syndrome 0.6 0.6 0
Chronic Kidney Disease 0.3 0.3
Chronic Lyme 0.3 -0.3
Chronic Obstructive Pulmonary Disease (COPD) 0.5 0.3 0.67
Chronic Urticaria (Hives) 0.3 0 0
Coagulation / Micro clot triggering bacteria 0.3 0.3 0
Cognitive Function 0.6 0.3 1
Colorectal Cancer 0.9 0.3 2
Constipation 0.3 0.3
Coronary artery disease 0.3 0.3 0
COVID-19 0.7 0.9 -0.29
Crohn's Disease 0.6 0.3 1
Cushing's Syndrome (hypercortisolism) 0.3 -0.3
cystic fibrosis 0.3 -0.3
deep vein thrombosis 0 0.6 0
Denture Wearers Oral Shifts 0.5 0.5
Depression 0.7 0.6 0.17
Dermatomyositis 0.3 0.3
Eczema 0.3 0.6 -1
Endometriosis 0.6 0.6
Eosinophilic Esophagitis 0.3 -0.3
Epilepsy 0.6 0.3 1
erectile dysfunction 0.4 0.4
Fibromyalgia 0.1 0.3 -2
Functional constipation / chronic idiopathic constipation 0.6 0.3 1
gallstone disease (gsd) 0 0
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0 0.3 0
Generalized anxiety disorder 0.6 0.6 0
Glioblastoma 0.3 -0.3
Gout 0.6 0.6
Graves' disease 0.3 0.6 -1
Gulf War Syndrome 0.3 0 0
Halitosis 0.6 0.3 1
Hashimoto's thyroiditis 0.3 0.3 0
Heart Failure 0.6 0.6
Hidradenitis Suppurativa 0.6 0.6
hyperglycemia 0.3 0.3 0
hypertension (High Blood Pressure 0.6 0.6 0
Hypoxia 0.3 0.3
IgA nephropathy (IgAN) 0.6 0.6
Inflammatory Bowel Disease 1 0.6 0.67
Insomnia 0.8 0.6 0.33
Intelligence 0.3 0.3
Intracranial aneurysms 0.3 0.3
Irritable Bowel Syndrome 0.6 0.6 0
ischemic stroke 0.6 0.3 1
Liver Cirrhosis 0.9 0.6 0.5
Long COVID 0.7 0.3 1.33
Mast Cell Issues / mastitis 0.3 0.3
ME/CFS with IBS 0.3 0.3 0
ME/CFS without IBS 0.3 0.3 0
membranous nephropathy 0.3 0.3
Menopause 0.3 0.3
Metabolic Syndrome 0.6 0.6 0
Mood Disorders 0.6 0.6 0
multiple chemical sensitivity [MCS] 0.5 0.5
Multiple Sclerosis 0.5 0.6 -0.2
myasthenia gravis 0.3 0.3
neuropathic pain 0.3 -0.3
Neuropathy (all types) 0.3 0.3
neuropsychiatric disorders (PANDAS, PANS) 0.3 0.3
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.7 0.3 1.33
NonCeliac Gluten Sensitivity 0.3 0.3 0
Obesity 0.6 0.9 -0.5
obsessive-compulsive disorder 0.6 0.6 0
Osteoarthritis 0.7 0.6 0.17
Osteoporosis 0.3 0.6 -1
pancreatic cancer 0.3 0.3 0
Parkinson's Disease 0.9 0.9 0
Polycystic ovary syndrome 0.6 0.6 0
primary biliary cholangitis 0.3 0.3 0
Primary sclerosing cholangitis 0.6 0.6
Psoriasis 0.3 0.3 0
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0.6 0.3 1
Schizophrenia 0.6 0.3 1
Sjögren syndrome 0.3 0.3 0
Sleep Apnea 0.3 -0.3
Slow gastric motility / Gastroparesis 0.3 0.3
Small Intestinal Bacterial Overgrowth (SIBO) 0.6 0.6
Stress / posttraumatic stress disorder 0.3 0.3 0
Systemic Lupus Erythematosus 0.6 0.2 2
Tic Disorder 0.3 0.3
Tourette syndrome 0.3 0.3 0
Type 1 Diabetes 0.6 0.6 0
Type 2 Diabetes 0.6 0.6 0
Ulcerative colitis 0.7 0.3 1.33
Unhealthy Ageing 0.6 0.6
Vitiligo 0.6 0.6

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