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🍽️ Dropropizine (R,S)

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  1. Cough Suppression: Dropropizine acts on the cough reflex center in the brain, reducing the frequency and intensity of coughing. It helps provide relief from both dry, non-productive coughs and coughs associated with excessive mucus production (productive coughs).

  2. Respiratory Infections: Dropropizine is commonly prescribed for cough relief in respiratory infections such as the common cold, flu (influenza), bronchitis, sinusitis, and other upper respiratory tract infections. It helps soothe irritated airways and suppress the urge to cough.

  3. Throat Irritation: Dropropizine may be used to alleviate coughing associated with throat irritation caused by postnasal drip, environmental irritants, or smoking.

  4. Allergic Cough: It can help relieve coughing triggered by allergies or allergic reactions, such as hay fever (allergic rhinitis) or allergic asthma.

  5. Chronic Bronchitis: Dropropizine may be part of the treatment regimen for chronic bronchitis, a long-term inflammation of the airways characterized by persistent coughing.

  6. Acute Pharyngitis: In cases of acute pharyngitis (sore throat), dropropizine can help reduce coughing and throat irritation, providing temporary relief from symptoms.

  7. Preoperative and Postoperative Cough: Dropropizine may be used before or after surgical procedures to suppress coughing, particularly in patients undergoing procedures that may irritate the airways or throat.

  8. Productive Cough: While primarily a cough suppressant, dropropizine may also help loosen and facilitate the removal of mucus from the respiratory tract, especially in cases of productive cough.

  9. Pediatric Use: Dropropizine may be prescribed for children above a certain age for cough relief associated with respiratory infections. However, it is important to use pediatric formulations and follow pediatric dosing guidelines.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of Dropropizine (R,S) On Probiotics

Rank Probiotic Impact

Bacteria Impacted by Dropropizine (R,S)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Odoribacter genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Streptococcus genus Decreases
0 1 Bacteroides genus Decreases
0 1 Coprococcus genus Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Streptococcus salivarius species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Alistipes finegoldii species Decreases
1 0 Bacteroides fragilis species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Streptococcus parasanguinis species Decreases
0 1 Butyricimonas faecalis species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Coprobacter fastidiosus species Decreases
0 1 Alistipes onderdonkii species Decreases
0 1 Alistipes communis species Decreases
0 1 Alistipes senegalensis species Decreases
1 0 Coprococcus comes species Decreases

Impact of Dropropizine (R,S) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
ADHD 0.7 0 0
Allergic Rhinitis (Hay Fever) 0.3 0.3 0
Allergies 0.4 0.7 -0.75
Allergy to milk products 0.3 0.1 2
Alzheimer's disease 0.7 0.9 -0.29
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.5 0.2 1.5
Ankylosing spondylitis 0.3 0.3 0
Anorexia Nervosa 0.4 0.9 -1.25
Antiphospholipid syndrome (APS) 0.2 0.2
Asthma 1.1 0.3 2.67
Atherosclerosis 0.4 0.6 -0.5
Atrial fibrillation 0.7 0.1 6
Autism 0.9 0.9 0
Autoimmune Disease 0.2 0.2
Barrett esophagus cancer 0.2 -0.2
benign prostatic hyperplasia 0.1 -0.1
Biofilm 0.3 0.3
Bipolar Disorder 0.3 0.3 0
Brain Trauma 0.2 0.3 -0.5
Cancer (General) 0.3 0.3
Carcinoma 0.7 0.6 0.17
Celiac Disease 0.7 0.6 0.17
Cerebral Palsy 0.3 0.3 0
Chronic Fatigue Syndrome 0.9 1.3 -0.44
Chronic Kidney Disease 0.1 0 0
Chronic Lyme 0.1 -0.1
Chronic Obstructive Pulmonary Disease (COPD) 0.9 0.2 3.5
Chronic Urticaria (Hives) 0.2 0.1 1
Coagulation / Micro clot triggering bacteria 0.2 0.4 -1
Cognitive Function 0.5 0.5 0
Colorectal Cancer 1.4 0.1 13
Constipation 0.3 0.3
Coronary artery disease 0.4 0.5 -0.25
COVID-19 1 2 -1
Crohn's Disease 0.9 0.7 0.29
Cushing's Syndrome (hypercortisolism) 0.1 -0.1
cystic fibrosis 0.1 -0.1
deep vein thrombosis 0.2 0.5 -1.5
Denture Wearers Oral Shifts 0.6 0.6
Depression 1.1 0.6 0.83
Dermatomyositis 0.2 0.2
Eczema 0.2 0.7 -2.5
Endometriosis 0.3 0.5 -0.67
Eosinophilic Esophagitis 0.2 -0.2
Epilepsy 0.4 0.1 3
erectile dysfunction 0.1 0.1
Fibromyalgia 0.1 0.2 -1
Functional constipation / chronic idiopathic constipation 0.9 0.6 0.5
gallstone disease (gsd) 0.4 0.4
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.1 0.2 -1
Generalized anxiety disorder 0.3 0.3 0
Glioblastoma 0.2 -0.2
Gout 0.5 0 0
Graves' disease 0.3 0.5 -0.67
Gulf War Syndrome 0.2 0.1 1
Halitosis 0.3 0.2 0.5
Hashimoto's thyroiditis 0.4 0.1 3
Heart Failure 0.5 0.2 1.5
Hidradenitis Suppurativa 0.3 0.3
High Histamine/low DAO 0.2 -0.2
hypercholesterolemia (High Cholesterol) 0.3 0.3
hyperglycemia 0.4 0.1 3
hypertension (High Blood Pressure 0.5 0.9 -0.8
Hypothyroidism 0 0
Hypoxia 0.1 0.1
IgA nephropathy (IgAN) 0.5 0.2 1.5
Inflammatory Bowel Disease 0.8 1.4 -0.75
Insomnia 0.7 0.5 0.4
Intelligence 0.1 0.1
Intracranial aneurysms 0.3 0 0
Irritable Bowel Syndrome 0.6 0.5 0.2
ischemic stroke 0.5 0.1 4
Liver Cirrhosis 1.3 0.5 1.6
Long COVID 0.6 1 -0.67
Low bone mineral density 0 0
Lung Cancer 0.3 -0.3
Mast Cell Issues / mastitis 0.2 0.3 -0.5
ME/CFS with IBS 0.2 0.2 0
ME/CFS without IBS 0.2 0.1 1
membranous nephropathy 0.2 0.2
Menopause 0.2 0.2
Metabolic Syndrome 0.9 0.9 0
Mood Disorders 1.2 0.6 1
multiple chemical sensitivity [MCS] 0.6 0.6
Multiple Sclerosis 1 0.8 0.25
Multiple system atrophy (MSA) 0.2 0.2 0
myasthenia gravis 0.2 0.2
neuropathic pain 0.6 -0.6
Neuropathy (all types) 0.2 0.6 -2
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.7 0.6 0.17
NonCeliac Gluten Sensitivity 0.1 0.1 0
Obesity 1.3 1.3 0
obsessive-compulsive disorder 0.8 0.6 0.33
Osteoarthritis 0.4 0.5 -0.25
Osteoporosis 0.3 0.3 0
pancreatic cancer 0.5 0.2 1.5
Parkinson's Disease 1.6 0.7 1.29
Polycystic ovary syndrome 1.1 1.2 -0.09
Postural orthostatic tachycardia syndrome 0 0
primary biliary cholangitis 0.2 0.2 0
Primary sclerosing cholangitis 0.4 0.3 0.33
Psoriasis 0.5 0.1 4
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0.9 0.5 0.8
Rosacea 0.2 0.2
Schizophrenia 0.9 0.3 2
scoliosis 0 0.2 0
Sjögren syndrome 0.5 0.1 4
Sleep Apnea 0.3 0.1 2
Slow gastric motility / Gastroparesis 0.3 0.3
Small Intestinal Bacterial Overgrowth (SIBO) 0.3 0.3
Stress / posttraumatic stress disorder 0.1 0.1 0
Systemic Lupus Erythematosus 0.7 0.5 0.4
Tic Disorder 0.7 0.7
Tourette syndrome 0.2 0.1 1
Type 1 Diabetes 0.7 0.5 0.4
Type 2 Diabetes 0.9 0.7 0.29
Ulcerative colitis 0.4 0.7 -0.75
Unhealthy Ageing 0.4 0.4 0
Vitiligo 0.6 0.2 2

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