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🍽️ alexidine dihydrochloride

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  1. Antimicrobial Activity: Alexidine dihydrochloride exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and some viruses. It disrupts the integrity of microbial cell membranes, leading to cell death and inhibition of microbial growth. It is effective against both Gram-positive and Gram-negative bacteria, as well as antibiotic-resistant strains.

  2. Skin Disinfection: Alexidine dihydrochloride is commonly used as a skin disinfectant for preoperative skin preparation, wound cleansing, and general antiseptic purposes. It helps reduce the microbial load on the skin surface, minimizing the risk of surgical site infections and other healthcare-associated infections.

  3. Oral Antiseptic: In dentistry, alexidine dihydrochloride is used as an oral antiseptic for the treatment of gingivitis, periodontitis, and other oral infections. It can help reduce bacterial colonization in the oral cavity, inhibit plaque formation, and promote periodontal health when used as part of a comprehensive oral hygiene regimen.

  4. Ophthalmic Applications: Alexidine dihydrochloride is also utilized in ophthalmic solutions and formulations for the disinfection of contact lenses and the prevention of ocular infections. It helps to eliminate microbial contaminants on contact lenses and lens cases, reducing the risk of eye infections such as bacterial keratitis.

  5. Wound Care: In addition to skin disinfection, alexidine dihydrochloride may be used in wound care products for the management of acute and chronic wounds. It can help prevent wound contamination, reduce bacterial bioburden, and promote wound healing by creating a clean and conducive environment for tissue repair.

  6. Safety and Tolerability: While alexidine dihydrochloride is generally considered safe and well-tolerated when used as directed, some individuals may experience mild irritation or allergic reactions, particularly with prolonged or repeated exposure. It is essential to follow proper usage instructions and precautions provided by healthcare professionals or product labeling.

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Data Contradictions — Limits of Certainity

Impacted of alexidine dihydrochloride On Probiotics

Rank Probiotic Impact
genus Bacillus Reduces
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by alexidine dihydrochloride

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Collinsella genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Clostridium genus Decreases
1 0 Akkermansia genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Blautia genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Streptococcus genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Coprococcus genus Decreases
0 1 Dorea genus Decreases
0 1 Odoribacter genus Decreases
0 1 Veillonella genus Decreases
0 1 Eggerthella genus Decreases
0 1 Lachnospira genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Segatella genus Decreases
0 1 Roseburia genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Agathobacter genus Decreases
0 1 Clostridioides genus Decreases
0 1 Escherichia genus Decreases
0 1 Enterocloster genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Shigella genus Decreases
0 1 Bilophila genus Decreases
0 1 Parolsenella genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Wansuia genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Flavonifractor genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Wujia genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Coprobacter genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Olsenella genus Decreases
0 1 Massilistercora genus Decreases
0 1 Simiaoa genus Decreases
0 1 Anaerostipes genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Qiania genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Christensenella genus Decreases
0 1 Treponema genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Eubacterium genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Faecalibacillus genus Decreases
0 1 Longicatena genus Decreases
0 1 Adlercreutzia genus Decreases
0 1 Lactococcus genus Decreases
0 1 Monoglobus genus Decreases
0 1 Fannyhessea genus Decreases
0 1 Leyella genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Prevotella genus Decreases
0 1 Bacillus genus Decreases
0 1 Vescimonas genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Lachnoclostridium genus Decreases
0 1 Faecalibaculum genus Decreases
0 1 Faecalibacterium genus Decreases
0 1 Parvimonas genus Decreases
0 1 Phoenicibacter genus Decreases
0 1 Gemella genus Decreases
0 1 Acutalibacter genus Decreases
0 1 Solibaculum genus Decreases
0 1 Hungatella genus Decreases
0 1 Chordicoccus genus Decreases
0 1 Leuconostoc genus Decreases
0 1 Mogibacterium genus Decreases
0 1 Allocoprobacillus genus Decreases
0 1 Butyricicoccus genus Decreases
0 1 Intestinimonas genus Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Blautia obeum species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Coprococcus comes species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Escherichia coli species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia hominis species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Segatella copri species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Veillonella parvula species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Veillonella rodentium species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Coprococcus catus species Decreases
0 1 Veillonella dispar species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Segatella bryantii species Decreases
0 1 Dorea longicatena species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Shigella boydii species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Veillonella nakazawae species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Parolsenella catena species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Blautia liquoris species Decreases
0 1 Veillonella rogosae species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Christensenella minuta species Decreases
0 1 Flavonifractor plautii species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Bacteroides sp. M10 species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Blautia parvula species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Streptococcus australis species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Blautia argi species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Leyella stercorea species Decreases
0 1 Shigella sonnei species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Bacteroides faecium species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Actinomyces oris species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Streptococcus suis species Decreases
0 1 Veillonella atypica species Decreases
0 1 Treponema peruense species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Parvimonas micra species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Hungatella hathewayi species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Prevotella intermedia species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Bacteroides caecimuris species Decreases
0 1 Coprobacter fastidiosus species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Treponema denticola species Decreases
0 1 Ruminococcus albus species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Leyella lascolaii species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Enterocloster clostridioformis species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Bifidobacterium bifidum species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Alistipes communis species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Butyricimonas faecalis species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Paraprevotella clara species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Prevotella bivia species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Alistipes senegalensis species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Blautia hansenii species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Alistipes dispar species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Alistipes shahii species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Parabacteroides johnsonii species Decreases
0 1 Romboutsia sp. 13368 species Decreases
0 1 Blautia producta species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Streptococcus sp. A12 species Decreases
0 1 Enterocloster asparagiformis species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Prevotella dentalis species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of alexidine dihydrochloride on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 1 1
Acne 0.6 -0.6
ADHD 6.5 1.7 2.82
Age-Related Macular Degeneration and Glaucoma 1.2 0.5 1.4
Allergic Rhinitis (Hay Fever) 5 4.5 0.11
Allergies 10.7 6 0.78
Allergy to milk products 4.2 2.2 0.91
Alopecia (Hair Loss) 2.6 0.1 25
Alzheimer's disease 11.2 12.2 -0.09
Amyotrophic lateral sclerosis (ALS) Motor Neuron 5.7 1.9 2
Ankylosing spondylitis 7.8 2.8 1.79
Anorexia Nervosa 3 5.6 -0.87
Antiphospholipid syndrome (APS) 2.3 0.2 10.5
Asthma 9 4.8 0.88
Atherosclerosis 4.4 2.9 0.52
Atrial fibrillation 6.6 4.4 0.5
Autism 16.3 15.8 0.03
Autoimmune Disease 1.9 1.6 0.19
Barrett esophagus cancer 1 0.5 1
benign prostatic hyperplasia 0.8 0.6 0.33
Biofilm 3.7 3.7
Bipolar Disorder 4.3 2.7 0.59
Brain Trauma 1.8 2.5 -0.39
Breast Cancer 1.4 1.4
Cancer (General) 1.6 3.7 -1.31
Carcinoma 7.9 4.7 0.68
Celiac Disease 5.3 6.5 -0.23
Cerebral Palsy 3.2 2.4 0.33
Chronic Fatigue Syndrome 10.5 9.9 0.06
Chronic Kidney Disease 7 4.7 0.49
Chronic Lyme 0.6 1 -0.67
Chronic Obstructive Pulmonary Disease (COPD) 4.5 3.5 0.29
Chronic Urticaria (Hives) 2.6 2.1 0.24
Coagulation / Micro clot triggering bacteria 2.7 2.8 -0.04
Cognitive Function 4 3 0.33
Colorectal Cancer 12.6 4.8 1.63
Constipation 2.9 1.2 1.42
Coronary artery disease 4.8 5.3 -0.1
COVID-19 16.8 20 -0.19
Crohn's Disease 15.7 11.3 0.39
Cushing's Syndrome (hypercortisolism) 1.1 -1.1
cystic fibrosis 1.1 2.7 -1.45
d-lactic acidosis (one form of brain fog) 0.8 0.8
deep vein thrombosis 4 2.8 0.43
Denture Wearers Oral Shifts 2.5 2.5
Depression 19.4 16 0.21
Dermatomyositis 0.6 0.5 0.2
Eczema 3.6 3.4 0.06
Endometriosis 5.6 3.7 0.51
Eosinophilic Esophagitis 0.6 1.1 -0.83
Epilepsy 7.1 4.1 0.73
erectile dysfunction 2.5 0.6 3.17
Fibromyalgia 5.5 3.8 0.45
Functional constipation / chronic idiopathic constipation 9.7 7.2 0.35
gallstone disease (gsd) 5.7 2.2 1.59
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 3.1 2.6 0.19
Generalized anxiety disorder 5.8 3.8 0.53
giant cell arteritis 0.5 -0.5
Glioblastoma 0.1 0.9 -8
Gout 3.3 1.9 0.74
Graves' disease 3.2 4.9 -0.53
Gulf War Syndrome 2 2.8 -0.4
Halitosis 3.1 0.6 4.17
Hashimoto's thyroiditis 6.5 3.4 0.91
Heart Failure 7.9 4.3 0.84
hemorrhagic stroke 1.7 1.7
Hidradenitis Suppurativa 2.4 0.5 3.8
High Histamine/low DAO 2.2 1.1 1
hypercholesterolemia (High Cholesterol) 1.7 0.8 1.13
hyperglycemia 3.1 3.2 -0.03
Hyperlipidemia (High Blood Fats) 2 0.7 1.86
hypersomnia 0.3 1.4 -3.67
hypertension (High Blood Pressure 8.8 9.9 -0.13
Hypothyroidism 1.3 2.7 -1.08
Hypoxia 3.8 0.1 37
IgA nephropathy (IgAN) 3.4 7.1 -1.09
Inflammatory Bowel Disease 15.3 16.2 -0.06
Insomnia 4.2 5.9 -0.4
Intelligence 3 1.2 1.5
Intracranial aneurysms 2.6 1.4 0.86
Irritable Bowel Syndrome 12.4 9.6 0.29
ischemic stroke 4.8 2.8 0.71
Juvenile idiopathic arthritis 0.1 0.1 0
Liver Cirrhosis 13 8.7 0.49
Long COVID 13.1 13.7 -0.05
Low bone mineral density 0.1 2 -19
Lung Cancer 1.7 2.4 -0.41
Lymphoma 0.8 0.1 7
Mast Cell Issues / mastitis 1.9 1.6 0.19
ME/CFS with IBS 1.7 3.7 -1.18
ME/CFS without IBS 3 2.9 0.03
membranous nephropathy 0.6 0.6
Menopause 2.9 1.2 1.42
Metabolic Syndrome 14.1 14 0.01
Mood Disorders 19.3 13.7 0.41
multiple chemical sensitivity [MCS] 2.2 0.6 2.67
Multiple Sclerosis 11.5 9.8 0.17
Multiple system atrophy (MSA) 2.3 1.5 0.53
myasthenia gravis 1.5 1.2 0.25
neuropathic pain 0.5 4.1 -7.2
Neuropathy (all types) 2.1 2.2 -0.05
neuropsychiatric disorders (PANDAS, PANS) 1.6 0.2 7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 9.4 9 0.04
NonCeliac Gluten Sensitivity 3.1 1.1 1.82
Obesity 18.2 15.3 0.19
obsessive-compulsive disorder 8.5 6.9 0.23
Osteoarthritis 4.9 3.1 0.58
Osteoporosis 3.9 3.4 0.15
pancreatic cancer 1.6 0.5 2.2
Parkinson's Disease 14.5 12.7 0.14
Polycystic ovary syndrome 10.6 5.4 0.96
Postural orthostatic tachycardia syndrome 0.6 1.1 -0.83
Premenstrual dysphoric disorder 1.5 0.6 1.5
primary biliary cholangitis 1.7 2.7 -0.59
Primary sclerosing cholangitis 4.5 5.2 -0.16
Psoriasis 6.1 4.8 0.27
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 12.9 7.6 0.7
Rosacea 1.8 1.1 0.64
Schizophrenia 11.9 6.2 0.92
scoliosis 1.4 1.4 0
sensorineural hearing loss 0.4 0.1 3
Sjögren syndrome 5.2 4.7 0.11
Sleep Apnea 3.7 2.7 0.37
Slow gastric motility / Gastroparesis 2.3 0.7 2.29
Small Intestinal Bacterial Overgrowth (SIBO) 4 0.6 5.67
Stress / posttraumatic stress disorder 5.2 4.5 0.16
Systemic Lupus Erythematosus 7.7 4.1 0.88
Tic Disorder 2.3 2.9 -0.26
Tourette syndrome 1.5 0.5 2
Type 1 Diabetes 7.4 6.4 0.16
Type 2 Diabetes 15.5 13.1 0.18
Ulcerative colitis 11.4 11.9 -0.04
Unhealthy Ageing 8 4.2 0.9
Vitiligo 3.9 2.8 0.39

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