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Anti-inflammatory Effects: Auranofin belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It works by exerting anti-inflammatory effects, helping to reduce joint inflammation, swelling, and pain associated with rheumatoid arthritis.
Disease Modification: Auranofin is considered a disease-modifying agent because it can slow down the progression of rheumatoid arthritis, prevent joint damage, and preserve joint function when used consistently over time.
Gold Therapy: Auranofin is a gold-containing compound and is classified as a disease-modifying antirheumatic drug (DMARD). Historically, gold-based compounds were commonly used in the treatment of rheumatoid arthritis, but their use has decreased with the advent of newer DMARDs such as methotrexate and biologic agents.
Oral Administration: Auranofin is typically administered orally in the form of tablets. The dosage and frequency of administration may vary depending on the severity of the rheumatoid arthritis and individual patient response.
Side Effects: Like all medications, auranofin can cause side effects. Common side effects may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, or abdominal pain. Some individuals may experience skin rash, itching, or mucocutaneous reactions. A rare but serious side effect is bone marrow suppression, which can lead to decreased production of blood cells (anemia, leukopenia, thrombocytopenia).
Monitoring: Patients taking auranofin require regular monitoring by their healthcare provider to assess treatment response and monitor for potential side effects. Blood tests may be performed to monitor liver function, kidney function, and blood cell counts.
Contraindications: Auranofin is contraindicated in individuals with known hypersensitivity to gold or any other component of the medication. It should be used with caution in patients with a history of significant gastrointestinal disorders or hematologic abnormalities.
Pregnancy and Lactation: Auranofin is not recommended for use during pregnancy or lactation unless the potential benefits outweigh the risks. Women of childbearing age should use effective contraception while taking auranofin.
Drug Interactions: Auranofin may interact with other medications, including certain antibiotics, anticoagulants, and immunosuppressants. Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential drug interactions.
Long-Term Use: Auranofin is generally used for the long-term management of rheumatoid arthritis. It may take several weeks to months to achieve maximum therapeutic benefit. Patients should continue taking the medication as directed by their healthcare provider, even if they start to feel better.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Explanations /Info /Descriptions are influenced by Large Language Models and may not be accurate and include some hallucinations.Please report any to us for correction.
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